<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation L63T
Rx PI-naive
IncludeMixtures No
References 41
Patients 63
Isolates 63
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Toni (2003)TTDdp55TTDdp55AY207699None   I13V, K14KR, I15V, K20I, M36I, N37T, P39S, R41K, L63T, I64M, H69K, L89MCRF02_AG
Lawrence (2006)04FR1104FR11DQ251607None   T12Q, I13L, K14R, G16X, K20I, M36I, L38I, L63T, H69K, L89MCRF02_AG
 00FR1400FR14DQ251610None   T12K, I13V, K14R, I15IV, G16GE, K20I, M36I, R41K, K45R, L63T, H69K, K70R, V82I, L89MCRF02_AG
 04FR1504FR15DQ251611None   L10I, T12K, I13V, G16E, K20I, E21D, M36I, P39L, L63T, H69K, V82I, L89M, F99LCRF02_AG
Tebit (2006)A461A461DQ682720None   V11D, I13V, K20I, M36I, N37M, R41K, L63T, H69R, L89MCRF02_AG
Caron (2008)1245Gab1245PEU556455None   T12K, I13V, G16E, G17E, K20I, M36I, N37D, K43R, L63T, I64L, H69K, L89MCRF02_AG
Delgado (2008)GH_205GH_205EU178036None   I13V, G16E, K20I, E35D, M36I, R41K, L63T, I64M, H69K, K70R, L89MCRF02_AG
Derache (2008)BKO-1059BKO-1059EU330735None   I13V, G16E, K20I, M36I, L63T, I64M, H69K, K70Q, L89I, I93MCRF02_AG
 SGO-42SGO-42EU330786None   L10I, I13V, K14R, K20I, M36I, R41K, L63T, H69Q, L89MCRF02_AG
Ayouba (2009)RES634RES634PRGQ351724None   I13V, K14R, I15T, K20I, M36I, R41K, L63T, I64M, H69K, L89MCRF02_AG
 0.6180.618-EPRGQ351830None   I13A, K14R, K20I, M36I, R41K, L63T, H69K, L89MCRF02_AG
Bartolo (2009)SNS10701AOSNS107EU068288None   L10I, I13V, K14R, G16E, K20I, M36I, R41K, L63T, H69A, L89MCRF02_AG
Hawkins (2009)R51ZZR51FJ931296None   I13V, K14R, I15V, K20I, M36I, R41K, L63T, I64M, H69K, L89MCRF02_AG
 R119ZZR119FJ931315None   L10I, I13V, K14R, G16E, L19P, K20I, M36I, R41K, L63T, H69K, K70R, L89MCRF02_AG
 R109ZZR109FJ931359None   I13A, K14R, K20M, A22V, E35D, M36I, R41K, L63T, I64V, H69K, K70R, L89MCRF02_AG
 R351ZZR351FJ931378None   I13V, K14R, G17E, K20I, M36L, R41K, K43R, L63T, I64M, H69K, K70R, L89MCRF02_AG
 R236ZZR236FJ931431None   L10V, T12S, I13A, K14R, K20I, E35D, M36I, R41K, L63T, H69K, L89MCRF02_AG
Tebit (2009)TR214TR214FJ577337None   I13V, K14R, G16E, K20I, M36I, R41K, L63T, H69K, K70R, L89MCRF02_AG
Vercauteren (2009)pt10177118950593GQ400007None   I13V, I15IV, G17E, K20I, M36I, P39M, R41RK, L63T, I64M, H69K, L89MCRF02_AG
Yebra (2009)SP78-400723SP78-400723EU362928None   I13V, K20I, E35D, M36I, R41K, L63T, I64M, H69K, L89MCRF02_AG
Djoko (2010)668CD3746FR666668None   I13V, K14R, K20I, E35K, M36I, N37E, R41K, L63T, I64M, H69K, L89MCRF02_AG
Yebra (2010)40072307SP400723FJ481668None   I13V, K20I, E35D, M36I, P39PL, R41K, L63T, I64M, H69K, L89MCRF02_AG
Aghokeng (2011)SK5015-PISK5015-PIHQ864442None   I13V, K14R, G17E, K20I, M36I, N37D, L63T, I64M, H69K, K70KR, L89MCRF02_AG
Charpentier (2011)CR-21CR-21FJ688227None   I13AV, K14R, K20I, M36I, R41K, L63T, H69K, L89MCRF02_AG
Dagnra (2011)08TG.E504408TG.E5044FR715280None  L33FI13V, K14R, L19P, K20R, M36I, N37D, R41RK, L63T, H69K, K70R, L89MCRF02_AG
 08TG.E506808TG.E5068FR715285None   T12S, I13V, I15L, K20I, M36I, R41K, L63T, I64M, H69K, K70R, L89MCRF02_AG
Hamers (2011)CP076303509CP076303509HQ993992None   I13V, K14R, K20I, M36I, R41K, L63T, I64IL, H69K, L89MCRF02_AG
 CP076303594CP076303594HQ994058None   I13V, K14R, K20I, M36I, R41K, K43R, L63T, I64M, H69K, L89MCRF02_AG
Afonso (2012)ANG40ANG40JN937053None   E35K, M36I, N37D, R41K, R57K, L63T, H69K, V82I, L89MCRF02_AG
 ANG46ANG46JN937059None   M36I, R41K, I62V, L63T, H69*, V77I, L89MCRF02_AG
 ANG47ANG47JN937060None   M36I, N37D, R41K, L63T, H69S, L89MCRF02_AG
Caron (2012)Gab013176Gab013176HQ541887None   I13A, K14R, G16E, K20I, M36I, R41K, L63T, H69K, L89MCRF02_AG
De Gascun (2012)IRL58518IRL58518JN622363None  V11IT12KN, I13V, K14R, K20I, M36I, N37ND, R41K, L63T, I64IM, H69KR, I72IT, L89MCRF02_AG
Ndase (2012)5501055255010552KC900645None   I13V, K20R, E35D, M36I, R41K, L63T, H69K, L89MCRF02_AG
Avi (2013)105105JX431692None   I13V, K14R, G16E, K20I, M36I, P39L, R41K, L63T, I64M, H69K, L89MCRF02_AG
Billong (2013)MR028MR028KF192147None   I13V, K14KR, G17E, K20I, E35D, M36I, R41K, L63T, I64M, H69K, K70KR, L89MCRF02_AG
Frentz (2013)EHR-606204EHR-606204JX300549None   I13V, K14R, I15V, M36I, N37D, R41K, K43R, L63T, I64M, H69K, L89MCRF02_AG
 EHR-75605EHR-75605JX300826None   I13V, I15IV, G17E, K20I, M36I, P39M, L63T, I64M, H69K, L89MCRF02_AG
Hassan (2013)RS09000982RS09000982HQ441717None   L10V, L19P, E35D, M36I, N37D, R57K, L63T, H69K, L89MCRF02_AG
Pircher (2013)B1111B1111JX110298None  V11IL10M, T12K, I13V, K14R, G16E, L19P, K20I, E35D, M36I, P39T, R41K, L63T, H69K, V77I, L89MCRF02_AG
Theys (2013)48174817KY386674None  V11IL10V, T12A, I13V, K14R, I15V, G16E, K20V, E35D, M36I, R41K, K45R, L63T, I64M, H69K, K70R, I72V, L89MCRF02_AG
 134781134781 None   I13V, K14R, K20I, E35D, M36I, R41K, L63T, I64M, H69K, I72T, L89MCRF02_AG
 139007139007 None   I13V, K14R, K20I, E35D, M36I, R41K, L63T, I64M, H69K, I72T, L89MCRF02_AG
Thiam (2013)2750-HALD2750-HALDJN673612None   I13A, K14R, K20I, M36I, R41K, L63T, I64M, H69K, L89MCRF02_AG
Aghokeng (2014)TG-2-267TG-2-267KC350033None   L10I, I13V, L19P, K20I, M36I, N37D, R41K, L63T, I64L, C67Y, H69K, K70R, L89MCRF02_AG
 TG-2-417TG-2-417KC350078None   L10I, I13V, I15IV, L19P, K20I, M36I, R41K, L63T, H69HKNQ, K70R, V82I, L89MCRF02_AG
 CM-3-174CM-3-174KC350357None  V11IL10V, T12K, I13V, G16E, K20I, M36I, R41K, L63T, I64L, H69K, K70R, L89MCRF02_AG
 TG-1-378TG-1-378KC350119None   L10I, I13V, K14R, L19P, K20I, M36I, N37S, R41K, L63T, H69K, K70R, L89MCRF02_AG
 CM-1-150CM-1-150KC350323None   I13V, K14R, I15IV, K20I, M36I, N37D, R41K, L63T, I64M, G68E, H69R, L89MCRF02_AG
Loubet (2014)LILX011386LILX011386KJ467996None  V11IL10V, I13V, I15IV, K20R, M36I, N37D, R41K, L63T, H69K, L89MCRF02_AG
Bruzzone (2015)HM1433FHM1433FKP889079None   L10I, V11T, I13V, G16E, L19I, K20I, E35Q, M36I, N37S, R41K, L63T, H69K, K70R, L89MCRF02_AG
 MB0170FMB0170FEU914177None   L10I, I13V, G17GE, M36I, N37S, R41K, L63T, I64L, L89MCRF02_AG
Carvalho (2015)2020KM206058None   I13V, K14R, K20I, M36I, R41K, L63T, I64M, H69K, L89MCRF02_AG
Dauwe (2015)NA_21812NA_21812KT863941None  V11IL10I, T12TA, I13V, K14R, I15V, G16E, K20I, E35D, M36I, R41K, L63T, H69Q, L89MCRF02_AG
 AG_09081AG_09081KT863738None  V11II13A, K14R, G16E, L19P, K20I, M36I, R41K, K43R, L63T, H69K, K70R, L89ICRF02_AG
Diallo (2015)1-1-1791-1-179JX084116None   K20I, E35ED, M36I, P39Q, R41K, K43R, L63T, I64M, H69K, A71V, I72TCRF02_AG
 2-1-1272-1-127JX084241None   G17E, K20I, M36I, N37D, K43KR, R57K, D60E, L63T, H69K, I72IM, T74A, L89MCRF02_AG
Abdellaziz (2016)18003HA18003HAKT339009None   L10V, T12A, I13V, I15L, K20I, M36I, N37ND, R41K, L63T, H69K, K70KR, I72IT, L89MCRF02_AG
Castley (2016)P127215188P127215188KT228833None   L10I, I13V, I15V, L19P, K20I, E35D, M36I, R41K, K43R, L63T, H69K, K70R, L89MCRF02_AG
Fokam (2016)CIRCB-41AHCIRCB-41AHKR229789None   L10I, I13V, K14KR, G16E, K20I, M36I, R41RK, L63T, H69K, K70R, L89MCRF02_AG
Gashnikova (2016)31PRRT_31KX574397None   I13V, K14R, I15L, G16E, K20I, E35D, M36I, R41K, L63T, I64M, H69K, L89MCRF02_AG
Hattori (2016)A09_1089A09-201089-1AB863820None   I13V, K14R, K20I, M36I, R41K, L63T, I64L, H69K, K70KR, V82I, L89MCRF02_AG
Zeh (2016)3005280_053005280_05KU248517None   E35D, M36I, R41K, K43R, L63T, H69K, L89MCRF02_AG