<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation L63T
Rx PI-naive
IncludeMixtures No
References 34
Patients 56
Isolates 56
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Pandrea (2002)IP_97CIRMF5897CIRMF58AY140641None   I13V, K20R, E35D, M36I, N37D, R41K, L63T, I64M, H69K, I72T, L89MCRF02_AG
Arien (2005)VI2641VI2641DQ177226None   L10I, I13V, I15V, L19P, K20I, M36I, R41K, L63T, C67S, V82I, L89MCRF02_AG
Zeh (2005)99NG79599NG795AY103406None   L10I, I13V, K14R, G16E, E35D, M36I, R41K, L63T, H69Q, L89M, I93LCRF02_AG
Lawrence (2006)04FR1104FR11DQ251607None   T12Q, I13L, K14R, G16X, K20I, M36I, L38I, L63T, H69K, L89MCRF02_AG
 00FR1400FR14DQ251610None   T12K, I13V, K14R, I15IV, G16GE, K20I, M36I, R41K, K45R, L63T, H69K, K70R, V82I, L89MCRF02_AG
 04FR1504FR15DQ251611None   L10I, T12K, I13V, G16E, K20I, E21D, M36I, P39L, L63T, H69K, V82I, L89MCRF02_AG
Tebit (2006)A461A461DQ682720None   V11D, I13V, K20I, M36I, N37M, R41K, L63T, H69R, L89MCRF02_AG
Vidal (2006)NV_KS07202.KS072AM041010None   G16E, K20R, E35D, M36I, P39S, R41K, K45R, I62V, L63T, E65D, H69K, I72T, L89MCRF02_AG
Derache (2007)13201320EF064534None   L10I, I13V, K14R, G16E, E35D, M36I, L63T, H69K, K70R, L89MCRF02_AG
Caron (2008)1245Gab1245PEU556455None   T12K, I13V, G16E, G17E, K20I, M36I, N37D, K43R, L63T, I64L, H69K, L89MCRF02_AG
Delgado (2008)GH_205GH_205EU178036None   I13V, G16E, K20I, E35D, M36I, R41K, L63T, I64M, H69K, K70R, L89MCRF02_AG
Derache (2008)BKO-1059BKO-1059EU330735None   I13V, G16E, K20I, M36I, L63T, I64M, H69K, K70Q, L89I, I93MCRF02_AG
 SGO-42SGO-42EU330786None   L10I, I13V, K14R, K20I, M36I, R41K, L63T, H69Q, L89MCRF02_AG
Holguin (2008)SP94-246975SP94-246975EU342781None   L10V, I13V, G16E, K20R, E35D, M36I, P39S, R41K, K45R, L63T, E65D, H69K, L89MCRF02_AG
Ayouba (2009)RES634RES634PRGQ351724None   I13V, K14R, I15T, K20I, M36I, R41K, L63T, I64M, H69K, L89MCRF02_AG
 0.6180.618-EPRGQ351830None   I13A, K14R, K20I, M36I, R41K, L63T, H69K, L89MCRF02_AG
Bartolo (2009)CSE11801AOCSE118EU068201None  V11IL10I, I13V, I15V, G16E, K20I, E35D, M36I, N37K, R41K, L63T, H69Q, L89M, I93LCRF02_AG
Hawkins (2009)R51ZZR51FJ931296None   I13V, K14R, I15V, K20I, M36I, R41K, L63T, I64M, H69K, L89MCRF02_AG
 R119ZZR119FJ931315None   L10I, I13V, K14R, G16E, L19P, K20I, M36I, R41K, L63T, H69K, K70R, L89MCRF02_AG
 R109ZZR109FJ931359None   I13A, K14R, K20M, A22V, E35D, M36I, R41K, L63T, I64V, H69K, K70R, L89MCRF02_AG
 R351ZZR351FJ931378None   I13V, K14R, G17E, K20I, M36L, R41K, K43R, L63T, I64M, H69K, K70R, L89MCRF02_AG
 R236ZZR236FJ931431None   L10V, T12S, I13A, K14R, K20I, E35D, M36I, R41K, L63T, H69K, L89MCRF02_AG
Vercauteren (2009)pt10177118950593GQ400007None   I13V, I15IV, G17E, K20I, M36I, P39M, R41RK, L63T, I64M, H69K, L89MCRF02_AG
Yebra (2009)SP78-400723SP78-400723EU362928None   I13V, K20I, E35D, M36I, R41K, L63T, I64M, H69K, L89MCRF02_AG
Djoko (2010)668CD3746FR666668None   I13V, K14R, K20I, E35K, M36I, N37E, R41K, L63T, I64M, H69K, L89MCRF02_AG
Yang (2010)20106934742010693474JQ616900None  V11IL10I, T12Q, I13V, K14KR, I15V, L19P, K20I, E35D, M36I, R41K, L63T, H69K, L89MCRF02_AG
Aghokeng (2011)SK5015-PISK5015-PIHQ864442None   I13V, K14R, G17E, K20I, M36I, N37D, L63T, I64M, H69K, K70KR, L89MCRF02_AG
Charpentier (2011)CR-21CR-21FJ688227None   I13AV, K14R, K20I, M36I, R41K, L63T, H69K, L89MCRF02_AG
Dagnra (2011)08TG.E504408TG.E5044FR715280None  L33FI13V, K14R, L19P, K20R, M36I, N37D, R41RK, L63T, H69K, K70R, L89MCRF02_AG
 08TG.E506808TG.E5068FR715285None   T12S, I13V, I15L, K20I, M36I, R41K, L63T, I64M, H69K, K70R, L89MCRF02_AG
Hamers (2011)CP076301586CP076301586HQ993624None   K20R, E35D, M36I, R41K, L63T, H69K, L89M, T91V, I93LCRF02_AG
 CP076301629CP076301629HQ993778None   I13V, K14R, G16E, K20R, E35D, M36I, R41K, L63T, G68E, H69K, L89IM, T91V, I93LCRF02_AG
 CP076303509CP076303509HQ993992None   I13V, K14R, K20I, M36I, R41K, L63T, I64IL, H69K, L89MCRF02_AG
 CP076303594CP076303594HQ994058None   I13V, K14R, K20I, M36I, R41K, K43R, L63T, I64M, H69K, L89MCRF02_AG
Afonso (2012)ANG31ANG31JN937044None  I50FE35D, M36I, P39S, R41K, L63T, E65D, H69Q, I72T, L89MCRF02_AG
 ANG25ANG25JN937039None   E35D, M36I, P39S, R41K, L63T, E65D, I72T, L89MCRF02_AG
 ANG46ANG46JN937059None   M36I, R41K, I62V, L63T, H69*, V77I, L89MCRF02_AG
 ANG47ANG47JN937060None   M36I, N37D, R41K, L63T, H69S, L89MCRF02_AG
 ANG106ANG106JN937111None   E35D, M36I, R41K, R57K, L63T, E65D, H69N, I72T, R87E, L89MCRF02_AG
Caron (2012)Gab013176Gab013176HQ541887None   I13A, K14R, G16E, K20I, M36I, R41K, L63T, H69K, L89MCRF02_AG
De Gascun (2012)IRL36116IRL36116JN622355None   I13V, K20I, E34T, M36I, P39I, R41K, Q61N, I62M, L63T, C67E, H69R, K70MR, I72T, V77I, L89MCRF02_AG
 IRL58518IRL58518JN622363None  V11IT12KN, I13V, K14R, K20I, M36I, N37ND, R41K, L63T, I64IM, H69KR, I72IT, L89MCRF02_AG
Hingankar (2012)IN-NARI-4-031IN-NARI-4-031JN314920None   T12S, K14R, E35D, M36I, N37D, R41K, R57K, L63T, H69K, V82I, L89MCRF02_AG
Ugbena (2012)1-1-0751-1-075JX084015None   G16E, E35D, M36I, R41K, L63T, H69K, L89MCRF02_AG
 1-1-1791-1-179JX084116None   K20I, E35ED, M36I, P39Q, R41K, K43R, L63T, I64M, H69K, A71V, I72TCRF02_AG
 2-1-1272-1-127JX084241None   G17E, K20I, M36I, N37D, K43KR, R57K, D60E, L63T, H69K, I72IM, T74A, L89MCRF02_AG
Billong (2013)MR028MR028KF192147None   I13V, K14KR, G17E, K20I, E35D, M36I, R41K, L63T, I64M, H69K, K70KR, L89MCRF02_AG
 MR084MR084KF192250None  V11VIL10I, I13V, K14R, K20I, M36I, N37S, R41K, K43KR, R57K, D60E, Q61G, L63T, C67E, H69R, L89MCRF02_AG
Frentz (2013)EHR-75605EHR-75605JX300826None   I13V, I15IV, G17E, K20I, M36I, P39M, L63T, I64M, H69K, L89MCRF02_AG
Hassan (2013)RS09000931RS09000931HQ441673None   I13V, G16E, K20R, E35D, M36I, R41K, L63T, G68E, H69K, K70R, V82I, L89M, T91V, I93LCRF02_AG
Pircher (2013)B1111B1111JX110298None  V11IL10M, T12K, I13V, K14R, G16E, L19P, K20I, E35D, M36I, P39T, R41K, L63T, H69K, V77I, L89MCRF02_AG
 B1145B1145JX110331None   L10I, I13V, K14R, K20L, D29DN, E34T, E35D, M36I, N37E, P39A, K43R, Q61N, I62M, L63T, C67E, H69K, K70R, I72T, V77I, L89MCRF02_AG
 B1114B1114JX110301None   L10I, I13V, I15V, G16E, L19I, E35D, M36I, W42WG, L63T, H69K, K70R, L89MCRF02_AG
Thiam (2013)2750-HALD2750-HALDJN673612None   I13A, K14R, K20I, M36I, R41K, L63T, I64M, H69K, L89MCRF02_AG
Van Zyl (2013)10292136KC423643None   L10I, I13V, K14R, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, H69K, L89MCRF02_AG
Bartolo (2014)09AOHDP21609AOHDP216KF853801None   L10I, I13V, G16E, L19P, K20R, E35D, M36I, R41K, R57K, L63T, E65D, H69HNY, K70KR, L89MCRF02_AG