<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation L63P
Rx >= 1 PI
IncludeMixtures No
References 24
Patients 54
Isolates 61
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Si-Mohamed (2000)AS_FANAS_FANAF199275IDV I84V, L90ML89VL10I, I13V, L19P, K20I, M36I, N37S, R41K, L63P, H69K, K70R, A71V, I72MCRF02_AG
Papa (2002)63GR63AF385364RTV V82A I13V, K20R, E35D, M36I, N37D, R41K, L63P, H69K, L89M, I93LCRF02_AG
Venturi (2002)GV-29GV-29.1AF517281SQV134 V11VII13V, K14R, L19LP, K20I, M36I, R41K, K43R, Q61H, L63P, H69K, V82VI, L89ICRF02_AG
Montes (2004)MB_patMAS D01_MASD709AJ577944NFV8  L10I, I13V, K14Q, L19P, K20I, M36I, R41K, L63P, C67Y, H69K, L89MCRF02_AG
 MB_patALC02_ALC723AJ577727NFV, SQV, RTV91I84V, L90M L10I, I13V, K20I, E35D, M36I, R41K, K43R, L63P, H69K, A71V, L89ICRF02_AG
 MB_patALI01_ALI708AJ577728NFV14  T12E, I13V, K14R, G17E, K20I, M36I, L63P, I64L, H69K, L89MCRF02_AG
  02_ALI705AJ577729NFV16  T12E, I13V, K14R, G17E, K20I, M36I, L63P, I64L, H69K, L89MCRF02_AG
Non-B Workgroup (2005)PL1692558358AY900968NFV M46I, L90ML89VL10V, I13V, K20V, M36I, R41K, L63P, H69K, K70RCRF02_AG
  71340 NFV, UnknownNAM46I, I84V, L90ML33LI, L89VL10V, I13A, K14KR, K20IV, A22AV, E35EG, M36I, R41RK, K55KR, L63P, I66FV, H69K, K70R, P79PACRF02_AG
 IL32IL32b NFV22M46I, N88SL10LFI13V, K20I, M36I, P39L, R41K, I62V, L63P, H69K, L89MCRF02_AG
  IL32cAY901181NFV67M46I, N88S L10V, I13V, K20I, M36I, P39L, R41K, I62V, L63P, H69K, L89MCRF02_AG
 TK2008TK2008 RTV, IDV, NFV73  L10I, I13V, K20I, M36I, R41K, L63P, C67S, H69K, K70R, L89MCRF02_AG
 PL8155102969 IDV190  I13V, K14R, K20I, E35D, M36I, R41K, L63P, I64L, H69K, K70R, L89MCRF02_AG
Weber (2005)M64940M64940AY677452IDV, NFV, LPV293G48A, I54V, V82S, L90ML89VL10I, I13A, K14R, K20I, M36I, N37D, R41K, L63P, H69K, A71VCRF02_AG
 M86254M86254AY714445LPV, NFV143N88NS L10LV, I13V, K14N, K20I, L33LV, M36I, N37ND, L63P, I66IF, H69K, K70KR, A71AT, T74TS, L89IMCRF02_AG
 M64940M64940AY714453IDV, NFV195G48A, I54V, V82S, L90ML89VL10I, I13A, K14R, K20I, M36I, N37D, R41K, L63P, H69K, K70KR, A71VCRF02_AG
Baxter (2006)48-32243224-30624DQ878131PINAM46I, I47IV, L76V, I84VL33LI, Q58EL10I, I13A, K20I, A22V, M36I, R41K, L63P, I66F, H69K, K70R, L89I, T91SCRF02_AG
 48-71247124-30902DQ878967PINAM46I, I47V, L76V, I84VQ58EL10I, I13A, K14IR, L19P, K20I, M36I, N37D, R41K, K55KR, L63P, H69K, K70R, L89ICRF02_AG
Laurent (2006)CK2-5902CM-59AM279443IDV61  I13V, K14R, I15V, K20I, M36I, R41K, L63P, H69K, L89MCRF02_AG
Seyler (2007)239CS_239 IDV71  I13AV, K14R, K20I, M36I, R41K, L63P, H69K, L89MCRF02_AG
 282CS_282 NFV, IDV150L90ML89VL10V, T12TK, I13V, L19P, K20I, E35G, M36I, N37ND, Y59YC, L63P, E65EK, H69K, K70R, A71TCRF02_AG
 545CS_545 IDV170I84VL33I, L89VL10I, I13V, K14R, L19P, K20I, A22V, M36I, N37D, L38I, R41K, L63P, H69K, A71V, T74SCRF02_AG
 547CS_547 NFV268 G48GR, V82VDI13V, K14R, G16GR, K20I, M36IT, R41K, L63P, H69K, L89MCRF02_AG
von Wyl (2007)1205327019EF449829PINAL90M L10V, I13V, K14R, I15V, K20I, E35G, M36I, R41K, L63P, G68E, H69R, A71T, L89ICRF02_AG
Riddler (2008)RG60650RG60650w114 LPV114  I13V, G17E, K20I, E35K, M36I, R41K, L63P, H69K, L89MCRF02_AG
Sylla (2008)A2840A2840_C1DQ991637IDV   T12A, I13V, K14R, K20I, M36I, R41K, L63P, H69K, L89MCRF02_AG
  A2840_C2DQ991638IDV   T12A, I13V, K14R, K20I, M36I, R41K, L63P, H69K, L89MCRF02_AG
 B202B202_C1EF525647IDV M46I, L76V I13V, K20I, E35N, M36I, R41K, L63P, H69K, L89MCRF02_AG
  B202_C2EF525648IDV M46I, L76V L10V, I13V, K20I, E35N, M36I, R41K, L63P, I66F, H69K, L89MCRF02_AG
 C1055C10559_C1EF525666IDV I54V, V82T L10I, I13V, I15V, K20I, E35D, M36I, R41K, L63P, H69K, T74S, L89MCRF02_AG
Jallow (2009)TTT19Pat19 HIV1FM877574LPV   L10I, T12A, I13V, K14R, I15V, G16E, K20I, M36I, P39S, L63P, H69K, L89MCRF02_AG
Charpentier (2011)2CP001-032 Unknown, LPVNA L89VL10V, I13V, I15V, L19KR, K20I, E35G, M36I, N37ND, R41K, I62IV, L63P, H69K, K70N, A71T, T74TSCRF02_AG
Charpentier (2011)CR-22CR-22FJ688228PINA N83DL10I, I13V, I15IV, K20I, E35KN, M36I, N37E, P39PQ, R41K, K45R, I62V, L63P, H69Q, I72IV, L89ICRF02_AG
 CR-24CR-24FJ688230PINAM46I, N88NSL89VI13V, K14R, K20I, M36I, P39S, R41K, I62V, L63P, H69K, A71TCRF02_AG
 CR-17CR-17FJ688223PINAM46LL89VT4TP, L10V, I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, I64M, I66F, H69K, K70R, A71T, I72VCRF02_AG
 CR-25CR-25FJ688231PINAM46I, L76V, I84IV L10I, I13V, K20I, M36I, R41K, L63P, I66F, H69K, L89MCRF02_AG
Kouri (2012)CU294-10CU294-10JQ585376PINAM46L, I54V, I84VQ58E, L89VI13A, L19P, K20I, A22V, L33V, E35D, M36I, N37D, I62IV, L63P, I66F, H69K, A71V, T74A, Q92K, I93IVCRF02_AG
Kim (2013)Tx11259KC120863LPV   T12TK, I13AV, K14R, I15IV, G16GE, K20I, M36I, P39S, R41RK, L63P, H69K, V82VI, L89IMCRF02_AG
Rawizza (2013)PJ9681PJ9681KF241511LPV I54V, V82AL89VL10V, I13A, K14R, I15V, K20I, A22V, E35D, M36I, R41K, Q61H, L63P, H69KCRF02_AG
 LL5290LL5290KF241477LPV   T12A, I13V, K14R, I15V, K20I, E35D, M36I, N37D, R41K, K43R, L63P, H69K, L89MCRF02_AG
 PJ0771PJ0771KF241503LPV   I13A, K14R, I15IV, K20I, M36I, N37E, R41K, K43R, L63P, H69K, K70R, L89MCRF02_AG
 OU9780OU9780KF241513LPV   T12TK, I13V, I15IV, K20I, M36I, R41K, L63P, E65D, H69K, L89MCRF02_AG
 LN3979LN3979KF241473LPV   I13V, K14R, K20I, M36I, R41K, L63P, H69K, L89MCRF02_AG
Thiam (2013)674-HALD674-HALDJN673677LPV M46I, L76V I13V, K14R, K20I, M36I, N37E, L63P, I64L, H69K, K70R, L89IMCRF02_AG
Agyingi (2014)LB084LB084KF576443PINA  K20I, M36I, R41K, L63P, H69K, K70R, L89MCRF02_AG
 LB046LB046KF576475PINA  K20I, E35Q, M36I, N37D, R41K, R57K, L63P, H69K, L89MCRF02_AG
 LB083LB083KF576444PINA  K20I, E35N, M36I, N37D, R41K, L63P, H69K, L89MCRF02_AG
Grossman (2014)554554 LPV52M46I, I54V, V82AL10FI13V, G16Q, K20I, M36I, P39L, I62V, L63P, H69K, L89MCRF02_AG
  554KF135101LPV65M46I, I54V, V82AL10FI13V, G16Q, K20I, M36I, P39L, I62V, L63P, H69K, L89MCRF02_AG
Diaz (2015)RenG17164RenG17164KT748192PINAI54IL, L90LML23I, L33LII13V, G17E, K20IV, E35DGNS, M36I, K45R, L63P, H69K, A71IV, L89TCRF02_AG
Jenabian (2015)DR43DR43KF735847PINA  I13V, K14R, K20I, M36I, N37ND, R41K, L63P, I64L, H69K, K70R, L89MCRF02_AG
 DR42DR42KF735846PINA  I13V, K14R, I15L, K20I, M36I, R41K, L63P, H69K, L89MCRF02_AG
 DR27DR27KF735833PINA  I13V, K14R, Q18K, K20I, M36I, N37D, R41K, L63P, G68E, H69R, K70R, L89MCRF02_AG
 DR25DR25KF735831PINAM46I, L76V I13V, G16E, K20I, E35G, M36I, N37S, R41K, Q61H, L63P, H69K, L89MCRF02_AG
 DR24DR24KF735830PINA  I13V, K14R, G17E, K20I, M36I, R41K, L63P, H69K, K70Q, L89MCRF02_AG
 DR18DR18KF735826PINAM46I, L76V L10LV, I13V, K14R, G17E, K20I, E35ED, M36I, R41K, R57RK, Q61H, L63P, H69K, L89ICRF02_AG
 DR11DR11KF735822PINA  I13V, K14R, K20I, E35K, M36I, R41T, L63P, H69K, I72V, L89MCRF02_AG
 DR07DR07KF735818PINAI54V, V82FM46V, G73GA, L89VL10V, I13V, L19LI, K20I, E35N, M36I, R41K, I62V, L63P, I64M, I66F, H69K, K70R, A71AT, I72V, T74SCRF02_AG
 DR04DR04KF735815PINAM46I, I47V, L76V, I84V L10V, I13A, K20I, E35EG, M36I, I62V, L63P, I66F, H69K, L89I, T91SCRF02_AG
Abdellaziz (2016)1418914189KT339049PINA  T12S, I13V, I15V, L19I, K20I, M36T, R41K, L63P, H69K, I72V, L89MCRF02_AG
 1631716317KT339019PINA  T12A, I13V, K14R, I15V, G16E, K20I, E35DN, M36I, R41K, L63P, H69K, L89MCRF02_AG