<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation L63H
Rx PI-naive
IncludeMixtures No
References 37
Patients 76
Isolates 76
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Tebit (2002)99CMLB3199CMLB31AF355312None   L10V, I13V, K14R, G16E, L19P, K20I, T31S, M36I, R41K, K43R, L63H, H69K, I72V, L89MCRF02_AG
Vergne (2002)LVLBV03_09LVLBV03_09AJ313392None   I13V, K14R, G16E, K20I, M36I, R41K, L63H, H69K, L89MCRF02_AG
Toni (2003)TTDdp12TTDdp12AY207664None   I13V, G16E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MCRF02_AG
 TTDpci135TTDpci135AY207740None   I13V, K14RT, G16E, K20I, M36V, P39S, R41K, L63H, I64L, H69K, K70KR, L89MCRF02_AG
 TTDdp17TTDdp17AY207669None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63H, H69K, L89MCRF02_AG
Konings (2004)KF_Pat8200CM2140AY359764None   I13V, K20I, E35G, M36I, N37D, L63H, H69K, I72T, L89MCRF02_AG
Holguin (2005)SP_22158SP_22158AF455665None   I13V, K14R, G17E, K20I, M36I, L63H, H69K, K70R, L89MCRF02_AG
Holguin (2005)60602-0202_60602-2AY248322None   I13V, K20I, L33V, E34A, R41K, I62V, L63H, G68E, H69R, L89MCRF02_AG
Zeh (2005)99NG76199NG761AY103348None   T12K, I13V, K14R, G17E, K20I, M36I, R41K, L63H, H69K, L89M, I93LCRF02_AG
Babic (2006)DB_SI7658-01SI7658-01AJ971270None   I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, K43R, L63H, I64L, H69K, K70R, L89MCRF02_AG
Koizumi (2006)YK_04CM012YK_04CM012DQ461830None   I13V, K14R, K20I, M36I, R41K, L63H, H69K, K70E, L89MCRF02_AG
 YK_04CM015YK_04CM015DQ461831None   Q2P, I13A, K14R, K20I, M36I, L63H, H69K, K70E, L89MCRF02_AG
 YK_04CM039YK_04CM039DQ461843None   I13V, K14R, L19I, K20I, M36I, R41K, L63H, H69K, K70E, L89ICRF02_AG
Razafindratsimandresy (2006)RR_MAD-GP099MAD-GP099DQ345015None  V11IL10V, I13V, L19P, K20I, M36I, N37D, R41K, Q61N, L63H, H69K, V75VI, L89MCRF02_AG
Vergne (2006)LV_00GB-LBV03_0900GB-03_09AM181801None   I13V, K14R, G16E, K20I, M36I, R41K, L63H, H69K, L89MCRF02_AG
Derache (2007)12261226EF064485None   I13A, K14R, G16E, K20I, A22V, M36I, R41K, L63H, H69K, K70I, L89ICRF02_AG
 12521252EF064500None   I13A, G16E, K20I, A22V, M36I, R41K, L63H, H69K, K70I, L89ICRF02_AG
 13101310EF064529None   I13A, K14R, I15V, K20I, M36I, R41K, L63H, H69K, I72L, L89ICRF02_AG
Holguin (2007)571213571213EF583183None   I13V, K14R, G16GE, K20I, E35D, M36I, R41K, L63H, H69K, K70R, L89MCRF02_AG
Delgado (2008)GH_214GH_214EU178043None   I13V, K20I, M36I, L63H, H69K, V82I, L89MCRF02_AG
Derache (2008)SGO-51SGO-51EU330795None   T12P, I13A, K14R, L19P, K20I, M36I, R41K, L63H, I64V, H69K, L89ICRF02_AG
Ndembi (2008)CMYD-5204CMYD-52DQ990418None   I13V, K20I, M36I, N37D, R41K, L63H, H69K, K70R, I72M, L89MCRF02_AG
Aghokeng (2009)CDF0011CDF0011GU191622None   T12I, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63H, C67CW, H69K, L89MCRF02_AG
 CDE0042CDE0042GU191631None   L10M, V11T, I13V, L19I, K20I, E35D, M36I, R41K, L63H, H69K, K70P, I72V, L89MCRF02_AG
Ayouba (2009)0.0130.013-FPRGQ351799None   I13V, K14R, K20V, M36I, R41K, L63H, H69K, L89MCRF02_AG
 27312731HALDPRGQ351975None   I13A, K20I, M36I, R41K, L63H, H69K, K70R, L89ICRF02_AG
Hawkins (2009)R235ZZR235FJ931430None   I13V, K14R, G16GE, K20I, M36I, R41K, L63H, H69K, L89MCRF02_AG
 R448ZZR448FJ931458None   T12TA, I13V, G16GE, K20I, E35K, M36IL, N37D, R41K, K45KR, R57K, Q61QE, L63H, H69K, K70R, L89MCRF02_AG
Tebit (2009)TR146TR146FJ577300None   I13V, K14R, Q18P, K20I, E21K, E35D, M36I, R41K, I62V, L63H, G68E, H69N, L89ICRF02_AG
 TR172TR172FJ577318None   I13V, I15V, K20I, M36I, N37D, L63H, H69K, L89MCRF02_AG
 TR241TR241FJ577353None   I13V, K14R, G16E, L19P, K20I, E35D, M36I, N37S, R41K, L63H, H69K, L89ICRF02_AG
Vercauteren (2009)pt2140392038275GQ398884None   I13A, K14R, G16E, K20I, M36I, P39S, R41K, L63H, H69K, L89MCRF02_AG
 pt7768520746380GQ400248None   T12P, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63H, G68E, H69R, L89MCRF02_AG
 pt204PIm10DugrtGQ400820None   I13V, G17E, K20I, M36I, L63H, H69K, K70GR, L89ICRF02_AG
 pt116tYaF4lfcPBGQ400908None   I13V, K14R, K20I, M36I, N37D, R41K, I62V, L63H, H69K, I72M, T74S, L89MCRF02_AG
 pt98UZmUAk8dzsGQ400926None   I13V, K14R, K20I, M36I, R41K, L63H, H69K, L89MCRF02_AG
Yaotse (2009)HT05006TG.HT050FM955689None   I13A, K14R, L19S, K20I, A22V, E35D, M36I, R41K, L63H, H69K, K70R, L89ICRF02_AG
 HT24706TG.HT247FM955755None   T4P, Q7D, L10V, T12A, I13V, K14R, G16E, K20I, E35G, M36I, R41K, R57K, L63H, H69K, P79S, L89MCRF02_AG
Bonura (2010)1225_1221225_122GU969561None   I13V, K14R, K20I, M36I, N37D, R41K, K43KR, L63H, H69K, K70KR, L89MCRF02_AG
Diop-Ndiaye (2010)488HALD488HALDFN599738None   T12Q, I13A, K20V, A22V, M36I, R41K, L63H, H69K, L89ICRF02_AG
Yang (2010)20106934432010693443JQ616883None   T12D, I13V, K14R, G16E, K20I, E35D, M36I, L63H, I64V, H69K, V77I, L89MCRF02_AG
 20106934472010693447JQ616907None   I13V, G16E, L19Q, K20I, E35D, M36I, R41K, L63H, H69K, K70R, I72M, V77I, L89MCRF02_AG
Aghokeng (2011)SK9004-PISK9004-PIHQ864415None   I13V, K14R, G16E, L19T, K20I, M36I, K43R, L63H, I64M, H69K, L89MCRF02_AG
 SK3023-PISK3023-PIHQ864433None   I13V, K14R, G17E, K20I, M36I, N37H, R41K, L63H, I64M, H69K, K70E, L89MCRF02_AG
 SK3006-PISK3006-PIHQ864449None   I13A, K14R, I15IV, K20I, M36I, R41K, K43KR, L63H, I64IV, H69K, L89IMCRF02_AG
Dagnra (2011)08TG.T301708TG.T3017FR715254None  V11IT12A, I13A, K14R, I15IV, G16GE, K20I, M36I, R41K, I62V, L63H, H69K, L89ICRF02_AG
 08TG.T304208TG.T3042FR715259None   I13V, K20I, M36I, R41K, L63H, I64M, H69K, L89MCRF02_AG
 08TG.E501608TG.E5016FR715272None   T12S, I13V, K20I, M36I, R41K, K43R, L63H, H69K, L89MCRF02_AG
 08TG.E502008TG.E5020FR715274None   L10V, I13V, K14R, I15V, G16E, L19P, K20I, E35D, M36I, P39Q, R41K, L63H, H69K, L89MCRF02_AG
Hamers (2011)CP076303589CP076303589HQ994053None   T12A, I13V, K14R, G16E, K20I, E35D, M36I, N37ND, P39PS, R41K, K43R, L63H, H69K, V77VI, L89ICRF02_AG
 CP076303605CP076303605HQ994067None   I13V, I15IL, L19Q, K20I, M36I, N37D, R41K, K43R, L63H, H69K, I72IT, L89MCRF02_AG
 CP076303620CP076303620HQ994080None   E35D, M36I, R41K, R57K, L63H, H69K, I72IM, V77VI, V82I, L89MCRF02_AG
 CP076305144CP076305144HQ994100None   I13A, K14KR, K20I, M36I, R41K, L63H, H69K, L89IMCRF02_AG
 CP076305213CP076305213HQ994147None   I13A, G16E, L19P, K20I, A22V, E35D, M36I, R41K, L63H, H69K, K70KR, L89MCRF02_AG
Caron (2012)Gab031177Gab031177HQ541906None   I13V, K14R, G16E, K20I, M36I, R41K, L63H, H69K, L89MCRF02_AG
 Gab082254Gab082254HQ541938None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63H, H69K, V77I, L89ICRF02_AG
Chamberland (2012)C434SC434SHQ267558None   I13A, K14R, K20I, M36I, R41K, L63H, H69K, K70R, L89I, I93IMCRF02_AG
 C441SC441SHQ267566None   I13V, K14R, K20I, M36I, P39L, R41K, I62V, L63H, H69K, L89MCRF02_AG
 D305TD305THQ267609None   I13V, G16E, G17E, K20I, E35D, M36I, L63H, H69K, L89MCRF02_AG
 D338TD338THQ267632None   I13V, K14R, K20X, M36I, R41K, K43KR, L63H, H69K, L89ICRF02_AG
Karlsson (2012)SE_164SE_164JQ698781None   I13V, K14R, I15IV, K20I, M36I, N37ND, L63H, H69K, K70EQ, L89MCRF02_AG
Machado (2012)CUPL1092CUPL1092JN000064None   I13V, K14R, G16E, K20I, E35D, M36I, L63H, H69K, L89M, T91ACRF02_AG
Ugbena (2012)2-1-0732-1-073JX084188None   G16E, K20I, E35Q, M36I, N37D, R41K, L63H, H69K, L89IMCRF02_AG
 1-1-0111-1-011JX083996None   I15V, G17E, K20I, M36I, N37ND, R41K, L63H, I64IM, H69K, L89MCRF02_AG
 1-1-1581-1-158JX084095None   G16E, Q18H, K20I, M36I, R41RK, L63H, H69K, K70E, L89MCRF02_AG
Aghokeng (2013)HJ3133HJ3133JX983025None   L10LV, T12A, I13V, K14R, G16GE, K20I, E35D, M36I, R41K, L63H, H69K, L89MCRF02_AG
Frentz (2013)EHR-30027EHR-30027JX300055None   I13V, K14R, G17E, K20I, E35D, M36I, R41RK, L63H, H69K, L89MCRF02_AG
 EHR-40530EHR-40530JX300224None   T12A, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63H, H69K, K70E, V82I, L89I, T91A, I93V, L97ICRF02_AG
 EHR-41925EHR-41925JX300249None  V11IT12E, I13V, K14RS, L19LP, K20I, M36I, R41K, L63H, H69K, L89ICRF02_AG
 EHR-65404EHR-65404JX300640None   I13V, G17E, K20I, M36I, L63H, H69K, K70R, L89ICRF02_AG
 EHR-95215EHR-95215JX301112None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, L63H, H69K, L89MCRF02_AG
Kebe (2013)SNA3-248SNA3-248JN193491None  V11II13V, K14R, G17E, K20I, M36I, N37D, L63H, H69K, K70KR, L89ICRF02_AG
 SN432HALDSN432HALDHM002505None  V11IT12K, I13AV, K14KR, I15IV, G16E, K20I, M36I, R41K, K43R, I62V, L63H, I64L, H69K, L89ICRF02_AG
Nii-Trebi (2013)128032128032AB751409None   T12TA, I13AV, K14R, G16E, K20I, A22AV, E35Q, M36I, N37D, R41K, R57K, L63H, H69K, L89ICRF02_AG
 KF372KF372AB751498None  V11II13V, L19P, K20I, M36I, R41K, L63H, H69K, L89ICRF02_AG
 KF49KF49AB751472None   I13A, K20I, M36I, N37D, R41K, L63H, H69K, K70KR, L89MCRF02_AG