<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation I54V
Rx >= 1 PI
IncludeMixtures No
References 12
Patients 35
Isolates 38
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Snoeck (2002)BE2BE2AF338979IDV, SQV, RTV, NFV109V32I, I47V, G48V, I54V, V82ATF53FL, L89VL10V, I13V, L19IT, K20I, M36I, R41K, K55H, L63P, C67S, H69R, A71IVCRF02_AG
Montes (2004)MB_patKON00_KON723AJ577921IDV, NFV117I54V L10V, I13V, K14R, K20I, E35G, M36I, R41K, I64M, H69K, A71V, L89ICRF02_AG
Non-B Workgroup (2005)PL3560858508AY900971IDV, NFV M46I, I54V, V82A, L90M I13V, K14KR, I15V, L19V, K20I, E35D, M36I, I64M, H69K, L89MCRF02_AG
 PL3515957564AY901074IDV, NFV160M46I, I54V, I84IV, L90ML89VI13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, A71TCRF02_AG
 PL53161101108 NFV52I54V, L90M I13V, G16E, K20I, E35D, M36I, R41K, I66F, H69K, K70R, L89MCRF02_AG
Baxter (2006)12-31973197-30821DQ876738PINAI54V, V82AL89VL10V, I13A, K14R, K20I, A22V, M36I, R41K, I62V, H69K, G73D, T74S, T91TSCRF02_AG
  3197-40128DQ876116PI, RTV, TPV>23I54V, V82AL89VL10V, I13A, K14R, K20I, A22V, L33L_L, M36I, R41K, I62V, H69K, G73D, T74S, T91TSCRF02_AG
 48-12441244-30527DQ877767PINAM46L, I54V, V82A, I84VV11VI, L33F, K43T, F53LT4A, L10V, I13V, G16A, L19P, K20M, E21A, E35D, M36L, K55R, Q61H, L63P, H69K, T74AS, L89I, T91SCRF02_AG
 48-30363036-30310DQ877947PINAM46L, I54V, I84V, L90ML33I, L89VL10I, T12A, I13A, L19P, K20V, A22V, M36I, R41K, I66F, H69K, K70R, A71V, Q92KCRF02_AG
 48-30903090-30925DQ877999PINAM46I, I47V, I54V, V82C, I84VV11I, L33I, K43T, F53FLL10I, T12M, I13V, K14R, L19P, K20I, A22V, M36I, R41K, K55R, H69K, K70R, I72V, T74S, L89I, T91SCRF02_AG
 48-40814081-30228DQ878310PINAM46L, I54V, I84V L10V, I13A, K14R, K20I, A22V, E35D, M36I, N37S, R41K, Q61H, I66F, H69K, K70R, P79S, L89I, T91TSCRF02_AG
 48-41674167-30423DQ878400PINAM46L, I54V, I84V L10I, I13A, L19P, K20I, A22V, E35D, M36I, N37S, R41K, D60E, I66F, H69K, A71V, L89I, T91S, Q92KCRF02_AG
  4167-40203DQ878401PI, RTV, TPV>41M46L, I54V, I84V L10I, I13A, A22V, E35D, M36I, N37S, R41K, D60E, I66F, H69K, A71V, L89I, T91S, Q92KCRF02_AG
 48-50755075-30807DQ878585PINAM46L, G48T, I54V, V82A, I84VV11VILL10I, T12TS, I13V, K14R, L19P, K20I, E35D, M36I, N37NS, R41K, Q61H, H69K, T74S, L89I, T91SCRF02_AG
Rosen-Zvi (2008)4600p46-1 RTV, SQV, NFV, APV141M46MIL, I54V, V82M, I84V, L90ML33F, Q58EL10V, T12V, I13IV, K14KR, I15V, K20R, E35D, M36I, N37E, R41K, R57K, L63P, H69K, L89ICRF02_AG
Charpentier (2011)CR-34CR-34FJ688240PINAM46I, I54V, I84V L10I, I13A, K14R, K20I, M36I, R41K, K43R, H69K, K70R, A71I, P79S, L89T, Q92K, I93MCRF02_AG
Barber (2012)6605166051JQ361680LPV I54V, V82A I13V, K14R, K20I, M36I, R41K, I64L, H69K, K70R, L89MCRF02_AG
Kouri (2012)CU294-10CU294-10JQ585376PINAM46L, I54V, I84VQ58E, L89VI13A, L19P, K20I, A22V, L33V, E35D, M36I, N37D, I62IV, L63P, I66F, H69K, A71V, T74A, Q92K, I93IVCRF02_AG
 CU344-10CU344-10JQ585386PINAM46L, I54V, I84VQ58EI13A, K20I, E35N, M36I, Q61QR, L63P, H69K, K70R, A71V, L89TCRF02_AG
 CU785-09CU785-09JQ585264PINAI54V, L90M I13V, K14R, G16E, K20I, E35D, M36I, N37K, P39S, R41K, I62V, H69K, A71V, I72V, T74S, L89ICRF02_AG
Rawizza (2013)LN3579LN3579KF241472LPV M46I, G48M, I54V, V82SL10F, K43TI13V, K14R, K20I, E35D, M36I, R41K, C67E, H69R, T74S, L89IMCRF02_AG
 PJ9681PJ9681KF241511LPV I54V, V82AL89VL10V, I13A, K14R, I15V, K20I, A22V, E35D, M36I, R41K, Q61H, L63P, H69KCRF02_AG
 LN0319LN0319KF241469LPV M46I, I54V, V82AL10FI13V, K14R, G16E, K20I, E35D, M36I, R41K, K43R, I62V, H69K, T74E, L89MCRF02_AG
 LL2169LL2169KF241466LPV G48V, I54V, V82AL24LIL10IV, T12P, I13V, G16E, K20I, E35A, M36I, R41K, R57K, I62V, L63HPSY, C67CY, H69S, L89IMCRF02_AG
 LN4321LN4321KF241489LPV I54V, V82FQ58E, N83DL10V, T12M, I13A, K14KR, G16A, L19P, K20I, A22V, E35N, M36I, N37D, R41RK, Q61QH, L63P, H69K, A71V, L89I, I93MCRF02_AG
 PJ9959PJ9959KF241498LPV M46I, I54V, V82A L10I, I13V, K14R, G17E, K20I, M36I, N37S, R41K, C67H, H69K, P81PL, L89MCRF02_AG
 PJ2149PJ2149KF241459LPV M46LV, I54V, L76V, V82M, L90ML89IVT4S, L10IV, I13A, K20IV, A22V, E35D, M36I, N37DE, Q61E, I62V, L63P, C67F, H69K, A71I, I72L, P79A, T91S, Q92QKCRF02_AG
 LL5309LL5309KF241462LPV M46I, I54V, L76V, V82AL10F, Q58EI13V, I15V, G16E, K20I, E35D, M36I, R41K, L63R, I64M, H69K, K70R, L89M, T91ACRF02_AG
 PJ4782PJ4782KF241507LPV I54V, V82A I13V, K14R, G17E, K20I, M36I, I62V, L63P, C67E, H69K, L89MCRF02_AG
 LN8580LN8580KF241492LPV M46I, I54V, L76V, V82VA, I84IVL89VL10LI, I13V, G16A, K20I, M36I, R41K, H69K, K70R, A71AVCRF02_AG
 LL3779LL3779KF241464LPV G48V, I54V, V82TL89VI13V, K14R, K20I, M36I, R41K, H69K, A71VCRF02_AG
Thiam (2013)133-HALD133-HALDJN673604PINAM46I, I47V, I54V, I84VL33I, G73SL10I, V11L, I13V, L19P, K20I, M36I, R41K, Q61H, L63V, H69K, K70R, A71V, I72T, P79A, N83S, L89TCRF02_AG
 1837HALD1837HALDJX187611LPV M46I, I54V, L76V, I84VQ58EL10I, I13V, G16E, K20I, M36I, R41K, L63HR, H69K, K70R, I72V, L89MCRF02_AG
 471-HALD471-HALDJN673637LPV M46I, I47V, I54V, V82A, I84VV11I, F53LL10I, I13V, L19P, K20I, A22V, M36I, N37S, R41K, Q61H, H69K, A71V, L89I, T91SCRF02_AG
 495-HALD495-HALDJN673647LPV M46I, I47V, I54V, I84V, L90ML33I, L89VT4S, L10I, T12M, I13A, K14M, L19P, K20I, A22V, E35D, M36I, N37D, R41RK, R57K, Q61QH, I62IV, L63P, I66F, H69K, A71VCRF02_AG
Grossman (2014)554554 LPV52M46I, I54V, V82AL10FI13V, G16Q, K20I, M36I, P39L, I62V, L63P, H69K, L89MCRF02_AG
  554KF135101LPV65M46I, I54V, V82AL10FI13V, G16Q, K20I, M36I, P39L, I62V, L63P, H69K, L89MCRF02_AG
Nerrienet (2014)U0302042U0302042JN675764LPV M46I, I54V, V82A, L90ML10F, L33I, K43T, N88DV11L, I13V, L19LV, K20V, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71V, T74S, L89T, T91ACRF02_AG