<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation K43R
Rx PI-naive
IncludeMixtures No
References 61
Patients 136
Isolates 140
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Si-Mohamed (2000)AS_SOUAS_SOUAF199307None   T12K, I13A, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
Vergne (2000)LV10LV10AJ286136None   L10I, I13V, M36I, R41K, K43R, H69Q, L89MCRF02_AG
 LVMB92LVMBP2AJ287024None   I13A, K14R, K20I, E35D, M36I, N37D, R41K, K43R, H69K, K70R, L89MCRF02_AG
Balotta (2001)CB-3453CB-3453AF295295None   I13V, G16E, K20I, M36I, R41K, K43R, I64M, H69K, L89MCRF02_AG
Fonjungo (2002)CM233CM233AY051266None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, K43R, L63P, H69K, L89M, I93LCRF02_AG
Pandrea (2002)IP_97CIRMF0497CIRMF04AY140642None   I13V, K14R, I15V, G16E, K20I, E35D, M36I, R41K, K43R, L63P, H69K, K70R, L89MCRF02_AG
Tebit (2002)99CMLB3199CMLB31AF355312None   L10V, I13V, K14R, G16E, L19P, K20I, T31S, M36I, R41K, K43R, L63H, H69K, I72V, L89MCRF02_AG
Holguin (2003)SP_LP16SP_LP16AF455613None   T12P, I13V, K14G, K20I, M36I, R41K, K43R, H69K, K70R, L89MCRF02_AG
Toni (2003)TTDdp12TTDdp12AY207664None   I13V, G16E, K20I, E35D, M36I, R41K, K43R, L63H, H69K, L89MCRF02_AG
 TTDdp39TTDdp39AY207685None   I13V, K14R, G17E, K20I, M36I, R41K, K43R, Q61H, H69K, K70R, V77VL, L89MCRF02_AG
Kijak (2004)2339SA02CM.2339AY371143None   I13V, K14R, K20I, M36I, R41K, K43R, I64L, H69K, K70R, V82I, L89MCRF02_AG
Konings (2004)KF_Pat7900CM1157AY359761None   I13V, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
 KF_Pat8301CM5630AY359765None  V11II13A, K14R, K20I, M36I, R41K, K43R, H69K, L89ICRF02_AG
 KF_Pat8900CM5056AY359771None   I13V, K14R, K20I, M36I, R41K, K43R, I64M, H69K, L89MCRF02_AG
Arien (2005)VI2642VI2642DQ177216None   I13V, I15V, K20V, E35D, M36I, R41K, K43R, H69K, L89MCRF02_AG
Carr (2005)2404LE2404LEAY847434None   I13V, K20I, M36I, R41K, K43R, C67F, H69K, L89MCRF02_AG
Carr (2005)01NGPL64401NGPL644DQ013276None   I13V, K14R, K20V, M36I, R41K, K43R, H69K, L89ICRF02_AG
Holguin (2005)316-9898_316-98AY248318None   I13V, K14R, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
Kinomoto (2005)Gh_K38Gh_K38AB187548None   I13V, K14R, G16E, L19T, K20I, M36I, R41K, K43R, I64M, H69K, K70R, L89MCRF02_AG
Non-B Workgroup (2005)PL4013168517AY901086None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
 PL49802101502 None   I13V, K14R, G17E, K20I, M36I, N37K, R41K, K43R, H69K, L89MCRF02_AG
Toni (2005)97IC_PCI397_PCI3AJ866555None  L10FI13V, K14R, G17E, K20I, M36I, R41K, K43R, H69K, K70R, L89MCRF02_AG
Zeh (2005)99NG113399NG1133AY103320None   I13A, K14R, K20I, E35D, M36I, R41K, K43R, L63P, H69K, K70R, L89M, I93LCRF02_AG
 99NG113799NG1137AY103321None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, H69K, L89M, I93LCRF02_AG
 99NG135999NG1359AY103332None   I13V, K14R, L19P, K20I, M36I, R41K, K43R, H69K, L89M, I93LCRF02_AG
 99NG54199NG541AY103342None   I13V, G16E, K20I, M36I, R41K, K43R, H69K, L89M, I93LCRF02_AG
 99NG89599NG895AY103360None   I13V, K14R, L19P, K20I, M36I, R41K, K43R, L63P, H69K, L89I, I93LCRF02_AG
Babic (2006)DB_SI7658-01SI7658-01AJ971270None   I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, K43R, L63H, I64L, H69K, K70R, L89MCRF02_AG
Chin (2006)KRC40444044_0405DQ660478None   L10I, I13V, K14R, I15V, L19P, K20I, M36I, N37D, R41K, K43R, Q61H, L63P, H69K, L89MCRF02_AG
Ndongmo (2006)CM384CBN_CM384DQ394176None   I13V, E35D, M36I, N37D, R41K, K43R, L63S, H69K, I72V, L89M, I93LCRF02_AG
Njai (2006)MP57897CM.578AM279384None   I13AV, K14R, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
Ojesina (2006)AIO_DDJ025AIO_DDJ025DQ273925None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, L63C, H69K, L89MCRF02_AG
 AIO_DDJ102AIO_DDJ102DQ273930None   I13V, K14R, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
Vessiere (2006)AV_M6128NAV_M6128NDQ297207None   I13V, K14R, G17E, K20I, E35N, M36I, R41K, K43R, L63P, H69K, V77I, L89MCRF02_AG
Derache (2007)12071207EF064477None   I13V, I15V, K20I, M36I, R41K, K43R, H69K, V82I, L89MCRF02_AG
 12481248EF064499None   I13V, K14R, G17E, K20I, M36I, N37D, R41K, K43R, L63P, H69K, L89MCRF02_AG
 12741274EF064513None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, H69K, K70R, L89MCRF02_AG
 12781278EF064516None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, L63P, H69K, N83K, L89ICRF02_AG
 13181318EF064533None   L10V, I13V, K14R, G16E, K20V, E35D, M36I, R41K, K43R, H69K, I72M, L89MCRF02_AG
Gatanaga (2007)C03-51110021-1C03-51110021-1AB640121None   L10I, I13V, L19P, K20I, M36I, R41K, K43R, L63P, H69K, V77VI, L89MCRF02_AG
Holguin (2007)598078598078EF583226None   I13V, K14R, I15V, K20I, E35N, M36I, R41K, K43R, H69K, T74S, L89MCRF02_AG
 605305605305EF583241None   L10I, I13V, G16E, K20I, E35D, M36I, R41K, K43R, L63A, I64M, H69K, K70R, L89MCRF02_AG
McNulty (2007)Cam30Cam30PLDQ869215None   K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
  Cam30DBSDQ869214None   K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
Sagoe (2007)104GHN104EF550529None   I13V, K14R, K20I, M36I, R41K, K43R, I64IL, H69K, L89MCRF02_AG
Vicenti (2007)480067304REF376497None   I13V, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
 311237086REF376499None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, H69K, K70R, L89MCRF02_AG
Zhong (2007)D0067O5CN_067EF199596None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, H69K, L89MCRF02_AG
Caron (2008)1245Gab1245PEU556455None   T12K, I13V, G16E, G17E, K20I, M36I, N37D, K43R, L63T, I64L, H69K, L89MCRF02_AG
Delgado (2008)GH_024GH_024EU177900None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, L63S, H69K, K70R, L89ICRF02_AG
 GH_026GH_026EU177902None   I13V, K14R, K20V, M36I, R41K, K43R, L63PS, I64M, H69K, K70KR, L89MCRF02_AG
 GH_195GH_195EU178028None   I13V, G16E, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
 GH_212GH_212EU178041None   L10I, I13V, G16E, L19P, K20IV, E35D, M36I, R41K, K43R, L63S, H69R, L89MCRF02_AG
 GH_246GH_246EU178071None   T12A, I13V, K14R, K20I, M36I, R41K, K43R, L63P, H69K, L89MCRF02_AG
 GH_252GH_252EU178076None   I13V, K14R, G16GE, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
Derache (2008)BKO-910BKO-910EU330662None   I13A, K14R, G16E, K20V, A22V, M36I, R41K, K43R, L63S, H69K, L89ICRF02_AG
 BKO-941BKO-941EU330676None   I13V, K14R, G17E, K20I, M36I, R41K, K43R, L63P, H69K, I72L, L89ICRF02_AG
 BKO-1027BKO-1027EU330717None   I13V, L19P, K20I, T31I, M36I, N37D, R41K, K43R, H69K, K70R, L89MCRF02_AG
 SGO-37SGO-37EU330781None   I13V, K14R, K20R, M36I, N37D, R41K, K43R, R57K, H69K, L89MCRF02_AG
 SGO-45SGO-45EU330789None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, K43R, L63S, I64L, H69K, K70R, L89ICRF02_AG
Sylla (2008)B7166B7166_C1DQ991645None   I13A, K14R, K20I, M36I, R41K, K43R, H69K, K70R, L89ICRF02_AG
  B7166_C2DQ991646None   I13A, K14R, K20I, M36I, R41K, K43R, H69K, K70R, L89ICRF02_AG
 A1469A1469_C1EF525655None   I13V, K14R, G16D, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
  A1469_C2EF525656None   I13V, K14R, G16D, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
Aghokeng (2009)CDB0010CDB0010GU191620None   I13V, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
 CDC0028CDC0028GU191627None   L10V, I13V, K14R, L19P, K20I, M36I, N37D, R41K, K43R, L63P, H69K, K70R, L89MCRF02_AG
 DD0246DD0246GU191644None   I13V, K14KR, G16E, K20I, E35AD, M36I, R41K, K43R, K55KR, H69K, L89MCRF02_AG
 DC1_0074DC1_0074GU191647None   I13V, K14KI, L19S, K20I, E35G, M36I, N37ND, R41K, K43R, H69K, K70R, V77L, L89MCRF02_AG
Ayouba (2009)TE10150TE10150PRGQ351706None   I13V, G16E, K20I, E35D, M36I, N37E, R41K, K43R, H69K, L89MCRF02_AG
 RES609RES609PRGQ351713None   I13V, K14R, I15V, G16E, L19I, K20I, E35K, M36I, N37D, R41K, K43R, I62V, L63S, I64M, H69K, K70R, L89MCRF02_AG
 RES038RES038-1PRGQ351739None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, H69K, L89M, I93VCRF02_AG
Hawkins (2009)P645ZZP645FJ931149None   I13V, K14R, K20I, M36I, R41K, K43R, H69K, K70R, L89MCRF02_AG
 Q186ZZQ186FJ931195None   I13V, G16E, K20I, M36I, K43R, H69K, L89MCRF02_AG
 Q134ZZQ134FJ931232None   T12A, I13V, K14R, I15V, K20IV, E35D, M36I, N37D, R41K, K43R, L63HP, H69K, V82VI, L89MCRF02_AG
 Q142ZZQ142FJ931233None   T12A, I13A, K14KR, I15IV, K20I, M36I, R41K, K43R, L63PS, H69K, L89ICRF02_AG
 Q833ZZQ833FJ931236None   I13V, K14R, L19P, K20I, M36I, R41K, K43R, L63P, H69K, L89MCRF02_AG
 R65ZZR65FJ931302None   I13V, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
 R117ZZR117FJ931313None   I13V, G16E, K20I, E35D, M36I, N37HY, R41K, K43R, H69K, K70KR, L89MCRF02_AG
 R118ZZR118FJ931314None   I13A, K20I, M36I, R41K, K43R, H69K, L89ICRF02_AG
 Q595ZZQ595FJ931320None   I13V, K20I, E35D, M36I, R41K, K43R, I62V, L63V, I64L, H69K, V82I, L89MCRF02_AG
 R146ZZR146FJ931329None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, K43R, I62IV, H69K, L89MCRF02_AG
 Q111ZZQ111FJ931341None  L33FI13V, K14R, K20V, M36I, R41K, K43R, H69K, L89MCRF02_AG
 R351ZZR351FJ931378None   I13V, K14R, G17E, K20I, M36L, R41K, K43R, L63T, I64M, H69K, K70R, L89MCRF02_AG
 R469ZZR469FJ931393None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, K43R, L63P, H69K, L89MCRF02_AG
 R268ZZR268FJ931444None   I13A, K14R, I15V, K20I, M36I, N37E, R41K, K43R, L63P, H69K, K70R, L89MCRF02_AG
 R439ZZR439FJ931449None   I13A, K14R, I15V, K20I, M36I, R41K, K43R, L63P, H69KCRF02_AG
Koyalta (2009)4TCHAD-4FJ688174None   I13V, K14R, G16E, L19V, K20I, E35D, M36I, R41K, K43R, H69K, L89MCRF02_AG
Tebit (2009)TR162TR162FJ577312None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, H69K, L89MCRF02_AG
Vercauteren (2009)pt20221210645106GQ399002None   I13V, K14KR, G17E, K20I, E35D, M36I, N37S, R41K, K43R, L63LP, H69K, L89MCRF02_AG
 pt10157124625491GQ400009None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, H69K, K70R, L89MCRF02_AG
Yaotse (2009)HT05706TG.HT057FM955694None   K14R, I15V, K20I, M36I, R41K, K43R, L63P, H69KQ, I72M, V77I, L89MCRF02_AG
Chin (2010)K327K327GQ290743None   I13V, K14R, G16E, K20I, M36I, N37D, R41K, K43R, H69K, K70R, L89MCRF02_AG
Diop-Ndiaye (2010)L049L049FN599731None   I13V, K14R, I15V, K20I, M36I, N37E, R41K, K43R, L63LI, I64M, H69K, L89MCRF02_AG
Djoko (2010)GQ02708GQ027FN557335None   L10I, I13V, K14R, I15IV, K20I, E35KQ, M36I, N37D, R41K, K43R, R57K, L63P, C67E, H69KQ, L89MCRF02_AG
Germanaud (2010)55685568 None   I13A, K14R, I15V, K20I, M36I, N37D, R41K, K43R, L63S, H69K, K70R, L89ICRF02_AG
Zolfo (2010)A13458A 13458 RSHM565719None   I13V, K20I, M36I, N37T, R41K, K43R, L63P, H69K, K70KR, L89MCRF02_AG
  A 13458 M30HM565633None   I13V, K20I, M36I, N37T, R41K, K43R, L63P, H69K, K70KR, L89MCRF02_AG
Aghokeng (2011)HJ604HJ604JN639448None   I13V, K14R, I15V, K20I, E35N, M36I, N37D, R41K, K43R, L63P, H69K, L89MCRF02_AG
 HJ1814HJ1814JN639457None   I13V, K14R, K20I, M36I, R41K, K43R, L63PS, H69K, K70KR, V82I, L89MCRF02_AG
 HJ2079HJ2079JN639501None   I13V, G16E, K20I, E35D, M36I, R41K, K43R, H69K, K70R, L89MCRF02_AG
 SK9004-PISK9004-PIHQ864415None   I13V, K14R, G16E, L19T, K20I, M36I, K43R, L63H, I64M, H69K, L89MCRF02_AG
 SK9045-PISK9045-PIHQ864457None   I13V, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
Dagnra (2011)08TG.T300808TG.T3008FR715252None   I13A, L19P, K20I, M36I, N37S, R41K, K43R, Q61H, H69K, L89ICRF02_AG
 08TG.E501608TG.E5016FR715272None   T12S, I13V, K20I, M36I, R41K, K43R, L63H, H69K, L89MCRF02_AG
Fokam (2011)CIRCB-12062CIRCB-12062JQ796120None   I13V, G16E, L19I, K20I, E35K, M36I, R41K, K43R, H69K, L89MCRF02_AG
 CIRCB-11621CIRCB-11621JQ796137None   I13V, K14KR, K20I, M36I, R41K, K43R, H69K, K70KR, L89MCRF02_AG
 CIRCB-10124CIRCB-10124JQ796164None   L10LV, T12A, I13V, I15V, K20I, E35D, M36I, R41K, K43R, Q61H, L63P, G68E, H69R, K70R, L89MCRF02_AG
Hamers (2011)CP076303543CP076303543HQ994022None   I13V, K20I, E35N, M36I, N37D, R41K, K43R, R57RK, H69K, T74S, V77I, L89MCRF02_AG
 CP076303589CP076303589HQ994053None   T12A, I13V, K14R, G16E, K20I, E35D, M36I, N37ND, P39PS, R41K, K43R, L63H, H69K, V77VI, L89ICRF02_AG
 CP076303594CP076303594HQ994058None   I13V, K14R, K20I, M36I, R41K, K43R, L63T, I64M, H69K, L89MCRF02_AG
 CP076303605CP076303605HQ994067None   I13V, I15IL, L19Q, K20I, M36I, N37D, R41K, K43R, L63H, H69K, I72IT, L89MCRF02_AG
 CP076305148CP076305148HQ994103None   I13V, K14R, K20IR, M36I, N37D, R41K, K43R, L63S, H69K, L89MCRF02_AG
 CP076305220CP076305220HQ994153None   I13AV, G17GE, K20I, M36I, N37D, K43R, L63PS, I64IV, H69K, K70KR, L89MCRF02_AG
 CP076305222CP076305222HQ994155None   I13V, K14R, K20I, M36I, N37D, R41K, K43R, L63P, H69K, L89MCRF02_AG
Caron (2012)Gab081127Gab081127HQ541930None   L10V, T12K, I13V, K14R, G16E, K20I, M36I, R41K, K43R, H69K, L89M, L97FCRF02_AG
 Gab082191Gab082191HQ541954None   I13V, K14R, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
 Gab082017Gab082017JN704998None   T12S, I13V, K14R, G16E, K20I, M36I, P39L, R41K, K43R, I62V, H69K, L89MCRF02_AG
 Gab091233Gab091233JN705008None   I13V, K14R, I15V, G16E, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
Chamberland (2012)C511SC511SHQ267601None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, K43R, H69K, L89MCRF02_AG
 D326TD326THQ267623None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, Q58QP, L63S, I64L, H69K, L89MCRF02_AG
 D331TD331THQ267627None   I13V, G16E, L19I, K20I, E35N, M36I, R41K, K43R, L63S, H69K, L89MCRF02_AG
De Gascun (2012)IRL41649IRL41649JN622243None   L10I, T12TA, I13AV, L19P, K20I, M36I, R41K, K43R, L63P, C67Y, H69K, K70R, L89MCRF02_AG
 IRL24786IRL24786JN622254None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
 IRL46503IRL46503JN622257None   I13V, G16E, L19LI, K20I, E35D, M36I, R41K, K43R, H69K, L89MCRF02_AG
 IRL56766IRL56766JN622275None   I13V, G16E, K20I, E35D, M36I, R41K, K43R, R57K, I64V, H69K, K70R, L89MCRF02_AG
 IRL27158IRL27158JN622328None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
Machado (2012)CUPL0943CUPL0943HQ655376None   I13V, K14R, G16E, K20L, E35D, M36I, N37K, R41K, K43R, H69K, L89MCRF02_AG
Rolland (2012)AA039a07LAA039a07LJX447140None   L10I, I13V, K20I, M36I, R41K, K43R, C67D, H69R, I72M, L89M, I93LCRF02_AG
Telan (2012)1106349311063493AB747465None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, K43R, H69K, T74S, L89M, T91ACRF02_AG
Youngpairoj (2012)cm11bbcm11bbDQ166417None   I13V, K14R, G16E, K20I, E35D, M36I, R41K, K43R, L63P, H69K, K70R, L89MCRF02_AG
 cm1490cm1490DQ166394None   I13V, K14R, K20I, E35D, M36I, R41K, K43R, I64V, H69K, L89MCRF02_AG
Frentz (2013)EHR-036308EHR-036308JX299605None   L10V, T12K, I13V, G16E, K20I, M36I, R41K, K43R, H69K, K70R, L89MCRF02_AG
 EHR-20913EHR-20913JX299885None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, L63P, L89M, I93LCRF02_AG
 EHR-46061EHR-46061JX300307None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, L63S, I64L, H69K, L89MCRF02_AG
 EHR-46486EHR-46486JX300313None   I13V, K14R, G17E, K20I, M36I, N37S, R41K, K43R, L63I, I64M, H69K, K70R, L89M, I93LCRF02_AG
 EHR-64647EHR-64647JX300625None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
 EHR-77276EHR-77276JX300867None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
 EHR-96856EHR-96856JX301134None   I13V, K14R, G16E, K20I, M36I, R41K, K43R, L63P, L89M, I93LCRF02_AG
Hawke (2013)1601010916010109KC237966None   L10I, I13V, G16E, L19P, K20I, E35D, M36I, R41K, K43R, L63S, H69K, K70R, L89MCRF02_AG
Tramuto (2013)CV1266_20CV1266_20HQ667675None   I13V, K14R, L19P, K20I, M36I, N37ND, R41RK, K43R, L63P, H69K, L89IMCRF02_AG

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