<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation K43R
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 15
Isolates 15
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG3333_w0 NFV1  I13V, I15V, K20I, E35K, M36I, R41I, K43R, L63LP, H69K, L89MCRF02_AG
Venturi (2002)GV-29GV-29.1AF517281SQV134 V11VII13V, K14R, L19LP, K20I, M36I, R41K, K43R, Q61H, L63P, H69K, V82VI, L89ICRF02_AG
Holguin (2003)SP_LP13SP_LP13AF455611PINA  L19P, K20I, M36I, N37T, R41K, K43R, H69K, K70R, L89MCRF02_AG
 SP_LP15SP_LP15AF455612PINA  I13S, K14R, I15N, G16E, K20I, M36I, R41K, K43R, H69K, K70R, L89MCRF02_AG
Montes (2004)MB_patALC02_ALC723AJ577727NFV, SQV, RTV91I84V, L90M L10I, I13V, K20I, E35D, M36I, R41K, K43R, L63P, H69K, A71V, L89ICRF02_AG
Seyler (2007)265CS_265 IDV66  L10V, I13V, L19P, K20I, M36I, R41K, K43R, L63LP, H69K, L89MCRF02_AG
von Wyl (2007)1234924247EF449966PINAN88S L10I, I13V, K14R, I15V, G16E, K20M, E35D, M36I, R41K, K43R, R57K, L63H, H69Q, I72V, L89MCRF02_AG
Charpentier (2011)CR-34CR-34FJ688240PINAM46I, I54V, I84V L10I, I13A, K14R, K20I, M36I, R41K, K43R, H69K, K70R, A71I, P79S, L89T, Q92K, I93MCRF02_AG
Kim (2013)Tx07228KC120855LPV   L10I, I13V, K14KR, I15V, G16GE, L19P, K20I, M36I, N37D, R41K, K43R, Q61H, L63S, I64IL, H69K, L89M, F99LCRF02_AG
Rawizza (2013)LN0319LN0319KF241469LPV M46I, I54V, V82AL10FI13V, K14R, G16E, K20I, E35D, M36I, R41K, K43R, I62V, H69K, T74E, L89MCRF02_AG
 LL5290LL5290KF241477LPV   T12A, I13V, K14R, I15V, K20I, E35D, M36I, N37D, R41K, K43R, L63P, H69K, L89MCRF02_AG
 PJ0771PJ0771KF241503LPV   I13A, K14R, I15IV, K20I, M36I, N37E, R41K, K43R, L63P, H69K, K70R, L89MCRF02_AG
 LL4419LL4419KF241465LPV   I13V, G16E, K20I, M36I, R41K, K43R, H69K, L89MCRF02_AG
Jenabian (2015)DR38DR38KF735842PINA  T12TA, I13V, K14R, G16E, K20I, E35D, M36I, N37H, R41K, K43R, L63H, I64M, H69K, K70E, L89MCRF02_AG
 DR32DR32KF735838PINA  I13V, I15V, K20I, M36I, R41K, K43R, I64M, H69K, L89MCRF02_AG