<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation E35Q
Rx PI-naive
IncludeMixtures No
References 26
Patients 37
Isolates 37
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Janssens (2000)WJ_VI1035WJ_VI1035AJ276595None   I13V, K14R, I15L, K20I, E35Q, M36I, R41K, L63M, H69K, L89MCRF02_AG
Balotta (2001)CB-3280CB-3280AF295287None   I13V, K14R, I15V, K20I, E35Q, M36I, N37D, R41K, R57K, I64M, H69K, L89MCRF02_AG
Carr (2005)1569MV1569MVAY847385None   L10V, I13V, K20I, E35Q, M36I, N37D, R41K, H69K, T74S, L89MCRF02_AG
Kinomoto (2005)Gh_K16Gh_K16AB187540None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, G49E, L63S, I64M, H69K, L89MCRF02_AG
 Gh_K50Gh_K50AB187549None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, L63S, I64M, H69K, L89MCRF02_AG
 Gh_T8Gh_T8AB187553None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, L63S, I64M, H69K, L89MCRF02_AG
 Gh_K26Gh_K26AB187544None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, L63S, I64M, H69K, L89MCRF02_AG
 Gh_K8Gh_K8AB187539None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, L63S, I64M, H69K, L89MCRF02_AG
Vessiere (2006)AV_M9602NAV_M9602NDQ297227None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, R57RK, H69K, I72V, L89MCRF02_AG
von Wyl (2007)110700260EF449798None   L10LI, I13V, K14R, G16E, K20I, E35Q, M36I, R41K, R57RK, I62IV, I64IM, H69N, L89MCRF02_AG
Delgado (2008)GH_045GH_045EU177918None   I13V, G16E, K20I, E35Q, M36I, N37S, R41K, K43R, L63P, H69K, L89MCRF02_AG
 GH_239GH_239EU178064None   I13V, G16E, K20I, E35Q, M36I, N37D, R41K, H69K, K70R, I72IV, L89MCRF02_AG
Hawkins (2009)Q200ZZQ200FJ931205None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, H69K, L89MCRF02_AG
Vercauteren (2009)pt13814967504767GQ399643None   I13V, K14R, K20I, E35Q, M36I, R41K, L63P, H69K, L89MCRF02_AG
Diop-Ndiaye (2010)897hald897haldFN599753None   L10I, I13V, K20I, E35Q, M36I, R41K, L63P, H69N, L89MCRF02_AG
Germanaud (2010)55935593 None   T12I, I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, L63P, H69K, L89MCRF02_AG
Soares (2010)CM05_106CM05_106GU366153None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, I62V, L63P, C67E, H69K, V82I, L89MCRF02_AG
Aghokeng (2011)SK4081-PISK4081-PIHQ864431None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, H69K, L89MCRF02_AG
Charpentier (2011)CR-23CR-23FJ688229None   I13V, K14R, G17E, K20I, E35Q, M36I, N37D, L63P, H69K, L89MCRF02_AG
Hamers (2011)CP076305164CP076305164HQ994118None   I13V, K14R, K20I, E35Q, M36I, N37S, R41K, R57K, L63P, C67E, H69K, V77VI, L89MCRF02_AG
Caron (2012)Gab051118Gab051118JN704995None   I13V, G16E, K20I, E35Q, M36I, N37D, R41K, I64L, C67Y, H69K, L89MCRF02_AG
 Gab091002Gab091002JN705004None   L10V, I13V, I15V, G16E, K20I, E35Q, M36I, R41K, L63P, H69K, L89MCRF02_AG
De Gascun (2012)IRL59045IRL59045JN622262None   I13V, K14R, I15V, G17E, K20I, E35Q, M36I, R41K, I64M, H69K, L89MCRF02_AG
Somda (2012)48-1633-2248-1633-22HG529964None   I13A, G16E, K20I, E35Q, M36I, R41K, R57K, H69K, L89MCRF02_AG
Zhao (2012)LB045LB045JN864053None   T12A, I13V, K20I, E35Q, M36I, N37D, R41K, L63P, H69K, L89MCRF02_AG
Nii-Trebi (2013)128032128032AB751409None   T12TA, I13AV, K14R, G16E, K20I, A22AV, E35Q, M36I, N37D, R41K, R57K, L63H, H69K, L89ICRF02_AG
Aghokeng (2014)CM-3-018CM-3-018KC350337None   I13V, K14R, G16E, K20I, E35Q, M36I, N37D, R41K, I64M, H69K, L89MCRF02_AG
 CM-3-155CM-3-155KC350347None   T12A, I13V, K14R, G16E, K20I, E35Q, M36I, R41K, I64M, H69K, L89MCRF02_AG
Agyingi (2014)LB009LB009KF576504None   G16E, K20I, E35Q, M36I, R41K, I64M, H69K, L89MCRF02_AG
 LB098LB098KF576429None   Q18X, K20I, E35Q, M36I, N37D, R41K, L63P, H69K, L89MCRF02_AG
Diallo (2015)2-1-0082-1-008JX084129None   K20I, E35Q, M36I, R41K, R57RK, C67E, H69R, I72V, V82I, L89MCRF02_AG
 2-1-0732-1-073JX084188None   G16E, K20I, E35Q, M36I, N37D, R41K, L63H, H69K, L89IMCRF02_AG
Castley (2016)P070385435P070385435KT228442None   I13V, K14R, I15IT, K20I, E35Q, M36I, N37D, R41K, R57K, L63LP, H69K, L89MCRF02_AG
Fokam (2016)CIRCB-10AHCIRCB-10AHKR229766None   L10IV, I13V, K14R, G16E, K20I, E35Q, M36I, N37ND, R41K, L63S, H69K, K70KR, L89MCRF02_AG
Hattori (2016)C09_110936C09-51110936-1AB865342None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, K43R, R57K, L63P, C67E, H69K, V82I, L89MCRF02_AG
 C09_110932C09-51110932-1AB865338None   I13V, K14R, Q18R, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69R, V82I, L89M, I93LCRF02_AG
 C11_111179C11-51111179-1AB865585None   I13V, G17E, K20I, E35Q, M36I, N37D, R41K, H69K, L89MCRF02_AG