<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation E35Q
Rx PI-naive
IncludeMixtures No
References 28
Patients 44
Isolates 44
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Janssens (2000)WJ_VI1035WJ_VI1035AJ276595None   I13V, K14R, I15L, K20I, E35Q, M36I, R41K, L63M, H69K, L89MCRF02_AG
Balotta (2001)CB-3280CB-3280AF295287None   I13V, K14R, I15V, K20I, E35Q, M36I, N37D, R41K, R57K, I64M, H69K, L89MCRF02_AG
Carr (2005)1569MV1569MVAY847385None   L10V, I13V, K20I, E35Q, M36I, N37D, R41K, H69K, T74S, L89MCRF02_AG
Kinomoto (2005)Gh_K16Gh_K16AB187540None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, G49E, L63S, I64M, H69K, L89MCRF02_AG
 Gh_K50Gh_K50AB187549None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, L63S, I64M, H69K, L89MCRF02_AG
 Gh_T8Gh_T8AB187553None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, L63S, I64M, H69K, L89MCRF02_AG
 Gh_K26Gh_K26AB187544None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, L63S, I64M, H69K, L89MCRF02_AG
 Gh_K8Gh_K8AB187539None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, L63S, I64M, H69K, L89MCRF02_AG
Vessiere (2006)AV_M9602NAV_M9602NDQ297227None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, R57RK, H69K, I72V, L89MCRF02_AG
von Wyl (2007)110700260EF449798None   L10LI, I13V, K14R, G16E, K20I, E35Q, M36I, R41K, R57RK, I62IV, I64IM, H69N, L89MCRF02_AG
Delgado (2008)GH_045GH_045EU177918None   I13V, G16E, K20I, E35Q, M36I, N37S, R41K, K43R, L63P, H69K, L89MCRF02_AG
 GH_239GH_239EU178064None   I13V, G16E, K20I, E35Q, M36I, N37D, R41K, H69K, K70R, I72IV, L89MCRF02_AG
Hawkins (2009)Q200ZZQ200FJ931205None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, H69K, L89MCRF02_AG
Vercauteren (2009)pt13814967504767GQ399643None   I13V, K14R, K20I, E35Q, M36I, R41K, L63P, H69K, L89MCRF02_AG
Diop-Ndiaye (2010)897hald897haldFN599753None   L10I, I13V, K20I, E35Q, M36I, R41K, L63P, H69N, L89MCRF02_AG
Germanaud (2010)55935593 None   T12I, I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, L63P, H69K, L89MCRF02_AG
Aghokeng (2011)SK4081-PISK4081-PIHQ864431None   I13V, K14R, G16E, K20I, E35Q, M36I, R41K, H69K, L89MCRF02_AG
Charpentier (2011)CR-23CR-23FJ688229None   I13V, K14R, G17E, K20I, E35Q, M36I, N37D, L63P, H69K, L89MCRF02_AG
Caron (2012)Gab051118Gab051118JN704995None   I13V, G16E, K20I, E35Q, M36I, N37D, R41K, I64L, C67Y, H69K, L89MCRF02_AG
 Gab091002Gab091002JN705004None   L10V, I13V, I15V, G16E, K20I, E35Q, M36I, R41K, L63P, H69K, L89MCRF02_AG
De Gascun (2012)IRL59045IRL59045JN622262None   I13V, K14R, I15V, G17E, K20I, E35Q, M36I, R41K, I64M, H69K, L89MCRF02_AG
Somda (2012)48-1633-2248-1633-22HG529964None   I13A, G16E, K20I, E35Q, M36I, R41K, R57K, H69K, L89MCRF02_AG
Zhao (2012)LB045LB045JN864053None   T12A, I13V, K20I, E35Q, M36I, N37D, R41K, L63P, H69K, L89MCRF02_AG
Nii-Trebi (2013)128032128032AB751409None   T12TA, I13AV, K14R, G16E, K20I, A22AV, E35Q, M36I, N37D, R41K, R57K, L63H, H69K, L89ICRF02_AG
Aghokeng (2014)CM-3-018CM-3-018KC350337None   I13V, K14R, G16E, K20I, E35Q, M36I, N37D, R41K, I64M, H69K, L89MCRF02_AG
 CM-3-155CM-3-155KC350347None   T12A, I13V, K14R, G16E, K20I, E35Q, M36I, R41K, I64M, H69K, L89MCRF02_AG
Agyingi (2014)LB009LB009KF576504None   G16E, K20I, E35Q, M36I, R41K, I64M, H69K, L89MCRF02_AG
 LB098LB098KF576429None   Q18QH, K20I, E35Q, M36I, N37D, R41K, L63P, H69K, L89MCRF02_AG
Bruzzone (2015)HM1433FHM1433FKP889079None   L10I, V11T, I13V, G16E, L19I, K20I, E35Q, M36I, N37S, R41K, L63T, H69K, K70R, L89MCRF02_AG
Diallo (2015)2-1-0732-1-073JX084188None   G16E, K20I, E35Q, M36I, N37D, R41K, L63H, H69K, L89IMCRF02_AG
Boerma (2016)CP107100012CP107100012KX139318None   I13V, K14R, G16E, L19Q, K20I, E35Q, M36I, R41K, L63P, H69K, L89MCRF02_AG
Castley (2016)P070385435P070385435KT228442None   I13V, K14R, I15IT, K20I, E35Q, M36I, N37D, R41K, R57K, L63LP, H69K, L89MCRF02_AG
 P138354752DP138354752DKT228950None   I13V, K14R, I15V, K20I, E35Q, M36I, N37D, P39PS, R41K, L63P, H69K, L89M, C95C*W, L97LIV, F99FLCRF02_AG
Fokam (2016)CIRCB-10AHCIRCB-10AHKR229766None   L10IV, I13V, K14R, G16E, K20I, E35Q, M36I, N37ND, R41K, L63S, H69K, K70KR, L89MCRF02_AG
Hattori (2016)C11_66536C11-2066536-1AB864400None   I13V, G17E, K20I, E35Q, M36I, N37D, R41K, H69K, L89MCRF02_AG
 C11_66537C11-2066537-1AB864401None   I13V, G17E, K20I, E35Q, M36I, N37D, R41K, H69K, L89MCRF02_AG
 C11_111179C11-51111179-1AB865585None   I13V, G17E, K20I, E35Q, M36I, N37D, R41K, H69K, L89MCRF02_AG
Chaplin (2017)NJIH0288NJIH0288MF622839None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, V82I, L89MCRF02_AG
 NJIH0287NJIH0287MF622838None   I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, L63P, C67E, H69K, V82I, L89MCRF02_AG
 NJIH0252NJIH0252MF622803None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, C67E, H69R, V82I, L89MCRF02_AG
 NJIH0251NJIH0251MF622802None   I13V, K14R, K20I, E35Q, M36I, R41K, R57K, I64IM, C67E, H69R, V82I, L89MCRF02_AG
 NJIH0180NJIH0180MF622731None   I13V, K14R, G16E, K20I, E35Q, M36I, N37E, R41K, R57RK, H69K, K70R, L89MCRF02_AG
Verhofstede (2017)29942994MF754798None   T12K, I13V, K14R, K20I, E35Q, M36I, N37X, R41K, H69K, L89XCRF02_AG
 11011101MF754539None   I13V, G16E, K20I, E35Q, M36I, N37E, R41K, K43R, L63H, H69K, L89MCRF02_AG