<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation E35N
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 11
Isolates 12
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M15M15AY010377PINA L89VL10V, I13V, K14R, L19P, K20I, E35N, M36I, N37D, R41K, H69K, T74SCRF02_AG
 NY_M65M65AY010428PINA L89VL10V, I13V, K14R, L19LP, K20I, E35N, M36I, N37D, R41K, H69K, T74SCRF02_AG
Non-B Workgroup (2005)PL3892365841AY901082SQV, ATV M46I I13V, E35N, M36I, N37D, I64M, H69K, T74S, L89TCRF02_AG
Seyler (2007)164CS_164 IDV253  I13V, K20I, E35N, M36I, N37D, L63V, I64M, H69K, L89MCRF02_AG
Sylla (2008)B7127B7127_C1DQ991643IDV   I13V, G17E, K20I, E35N, M36I, R41K, K45R, R57K, L63S, H69K, K70R, I72T, L89MCRF02_AG
  B7127_C2DQ991644IDV   I13V, G17E, K20I, E35N, M36I, R41K, K45R, R57K, L63S, H69K, K70R, I72T, L89MCRF02_AG
Kouri (2012)CU672-11CU672-11JQ585515PINA  I13V, K14R, G16E, K20I, E35N, M36I, R41K, F53Y, I64M, H69K, K70R, L89MCRF02_AG
 CU1163-09CU1163-09JQ585277PINAM46ML, L90M I13V, G16E, K20I, E35N, M36IR, R41K, H69K, K70KR, L89MCRF02_AG
 CU344-10CU344-10JQ585386PINAM46L, I54V, I84VQ58EI13A, K20I, E35N, M36I, Q61QR, L63P, H69K, K70R, A71V, L89TCRF02_AG
 CU1288-10CU1288-10JQ585421PINAM46I, I54L, I84VV11I, L33F, Q58EL10I, I13V, K14R, I15V, G16E, L19P, K20V, E35N, M36I, N37D, K55R, R57RK, Q61H, L63S, H69K, K70R, I72IM, I85V, L89MCRF02_AG
Nii-Trebi (2013)KF307KF307AB751493NFV L90M I13V, K14R, G16E, K20I, E35N, M36I, P39S, R41K, I64IV, H69K, K70KR, V82I, L89MCRF02_AG
Rawizza (2013)LN4321LN4321KF241489LPV I54V, V82FQ58E, N83DL10V, T12M, I13A, K14KR, G16A, L19P, K20I, A22V, E35N, M36I, N37D, R41RK, Q61QH, L63P, H69K, A71V, L89I, I93MCRF02_AG