<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation E35K
Rx PI-naive
IncludeMixtures No
References 42
Patients 76
Isolates 78
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yerly (2001)L3213L3213AY998554None   L10V, I13V, L19P, K20I, E35K, M36I, N37E, R41K, H69K, K70R, L89MCRF02_AG
Toni (2003)TTDdp2TTDdp2AY207655None   I13V, K20I, E35K, M36I, N37T, R41K, H69K, L89MCRF02_AG
 TTDpci122TTDpci122AY207747None   I13V, K14R, I15V, K20I, E35K, M36I, R41N, H69K, L89MCRF02_AG
Vergne (2003)VL99SN123HALD99SN123AJ583711None   I13V, K20I, E35K, M36I, N37E, R41K, H69K, V77I, L89MCRF02_AG
Kijak (2004)0015BBY02CM.0015AY371127None   T12A, I13V, K14R, I15V, K20I, E35K, M36I, R41Q, H69K, K70R, L89MCRF02_AG
Konings (2004)KF_Pat5800CM4536AY359740None   I13V, K14R, G16E, K20I, E35K, M36I, R41K, H69K, L89MCRF02_AG
 KF_Pat7500CM1233AY359757None   L10V, T12N, I13V, K20I, E35K, M36I, R41T, L63S, H69K, L89MCRF02_AG
 KF_Pat8000CM2362AY359762None   I13V, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
 KF_Pat8100CM2878AY359763None   I13V, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
Carr (2005)3467NJ3467NJAY847370None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
 3153MN3153MNAY847362None   I13V, K20I, E35K, M36I, N37E, R41K, H69K, L89MCRF02_AG
 0015BBY0015BBYAY847416None   T12A, I13V, K14R, I15V, K20I, E35K, M36I, R41Q, H69K, K70R, L89MCRF02_AG
 3411NJ3411NJAY847367None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, R57K, H69K, L89MCRF02_AG
Carr (2005)01NGPL75401NGPL754DQ013282None   I13V, G16E, K20I, E35K, M36I, N37E, R41K, H69K, L89MCRF02_AG
 PL0754PL0754DQ168578None   I13V, G16E, K20I, E35K, M36I, N37E, R41K, H69K, L89MCRF02_AG
Kinomoto (2005)Gh_T5Gh_T5AB187552None   I13V, Q18R, K20I, E35K, M36I, R41K, D60N, H69K, K70R, L89MCRF02_AG
Zeh (2005)99NG51999NG519AY103335None   I13V, K14R, K20I, E35K, M36I, R41T, H69K, K70R, L89M, I93LCRF02_AG
Koizumi (2006)YK_04CM006YK_04CM006DQ461825None   L10V, I13V, K14R, K20I, E35K, M36I, N37D, R41K, H69K, K70R, L89MCRF02_AG
 YK_04CM032YK_04CM032DQ461839None   T12A, I13V, G16E, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
 YK_04CM050YK_04CM050DQ461847None   I13V, K14R, K20I, E35K, M36V, N37H, R41N, H69K, L89MCRF02_AG
Ndongmo (2006)CM126CBN_CM126DQ394132None   I13V, K20I, E35K, M36I, N37D, R41K, H69K, K70R, L89M, I93LCRF02_AG
Ojesina (2006)AIO_DDJ130AIO_DDJ130DQ273934None   I13V, K14R, G17E, K20I, E35K, M36I, N37E, H69K, L89MCRF02_AG
 AIO_DDJ150AIO_DDJ150DQ273939None   L10V, I13V, K14R, L19P, K20I, E35K, M36I, R41K, Q61H, H69K, L89M, C95VCRF02_AG
Vessiere (2006)AV_M3652NAV_M3652NDQ297259None   I13V, G17E, K20I, E35K, M36I, R41K, H69K, K70R, L89MCRF02_AG
Sagoe (2007)24GHN24EF174556None   L10I, I13V, K14KR, I15IV, G16E, K20I, E35K, M36I, R41N, H69K, K70R, L89MCRF02_AG
Caron (2008)1296Gab1296PEU556457None   I13V, K14R, L19P, K20I, E35K, M36I, N37D, R41K, I64L, H69K, K70R, V82I, L89MCRF02_AG
Delgado (2008)GH_132GH_132EU177980None   I13V, K14R, G17E, K20I, E35K, M36I, R41K, I64M, H69K, L89MCRF02_AG
 GH_254GH_254EU178077None   I13V, K14R, G17E, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
Ndembi (2008)CMYD-2704CMYD-27DQ990399None   I13V, K14R, G16E, K20I, E35K, M36I, R41N, I64M, H69K, L89MCRF02_AG
 CMYD-9604CMYD-96DQ990450None   I13V, K20I, E35K, M36I, N37D, R41K, L63P, H69K, L89MCRF02_AG
Aghokeng (2009)DG446DG446GU191638None   I13V, K14R, G17E, K20I, E35K, M36I, R41K, H69K, L89MCRF02_AG
Ayouba (2009)RES609RES609PRGQ351713None   I13V, K14R, I15V, G16E, L19I, K20I, E35K, M36I, N37D, R41K, K43R, I62V, L63S, I64M, H69K, K70R, L89MCRF02_AG
 RES034RES034-1PRGQ351738None   I13V, K20I, E35K, M36I, N37D, R41K, I64L, H69K, K70R, L89MCRF02_AG
Hawkins (2009)P606ZZP606FJ931123None   I13V, K14KR, K20I, E35K, M36I, R41T, R57RK, L63LP, I64IL, H69K, L89MCRF02_AG
 R468ZZR468FJ931392None   L10IV, I13V, I15V, K20I, E35K, M36I, R41N, K45R, L63P, C67S, H69K, L89MCRF02_AG
 R448ZZR448FJ931458None   T12TA, I13V, G16GE, K20I, E35K, M36IL, N37D, R41K, K45KR, R57K, Q61QE, L63H, H69K, K70R, L89MCRF02_AG
Vercauteren (2009)pt2123565203511GQ398901None   I13V, K14R, G17E, K20I, E35K, M36I, N37D, R41K, L63I, I64M, H69K, L89MCRF02_AG
 pt19141829667817GQ399110None   I13V, I15IV, K20I, E35K, M36I, N37D, R41K, L63P, H69K, L89MCRF02_AG
 pt18222388870450GQ399202None   I13V, K14R, G17E, K20I, E35K, M36I, R41K, H69K, L89MCRF02_AG
 pt18022495368620GQ399222None   I13V, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
 pt17692724895323GQ399255None   Q2QR, I13A, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
 pt10326pyeTIXgUzGQ399992None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, I66V, H69K, L89MCRF02_AG
Carr (2010)3153MN02CM.3153MNGU201513None   I13V, K20I, E35K, M36I, N37E, R41K, H69K, L89MCRF02_AG
Diop-Ndiaye (2010)123HALD123HALDFN599682None   I13V, K20I, E35K, M36I, N37E, R41K, H69K, V77I, L89MCRF02_AG
 962hald962haldFN599772None   L10V, I13V, K14R, K20I, E35K, M36I, N37E, R41K, H69K, L89MCRF02_AG
 1718-hald1718-haldFN599786None   I13V, K14R, K20I, E35K, M36I, N37E, R41K, H69K, L89MCRF02_AG
Djoko (2010)668CD3746FR666668None   I13V, K14R, K20I, E35K, M36I, N37E, R41K, L63T, I64M, H69K, L89MCRF02_AG
Soares (2010)CM04_091CM04_091GU366127None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
Aghokeng (2011)HJ1450HJ1450JN639505None   I13V, G16GE, K20I, E35K, M36I, N37ND, R41N, D60DE, Q61E, I64IM, H69K, L89MCRF02_AG
Aghokeng (2011)SK4105-PISK4105-PIHQ864451None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, R57RK, H69K, L89MCRF02_AG
Fokam (2011)CIRCB-12062CIRCB-12062JQ796120None   I13V, G16E, L19I, K20I, E35K, M36I, R41K, K43R, H69K, L89MCRF02_AG
Hamers (2011)CP076303489CP076303489HQ993978None   K20V, E35K, M36I, N37D, R41K, L63LP, H69K, V77VI, L89MCRF02_AG
 CP076303583CP076303583HQ994050None   I13V, K14R, I15IV, K20I, E35K, M36I, R41T, L63P, H69K, L89MCRF02_AG
Ajoge (2012)H34HP34HM854115None   L10V, T12E, I13V, G17E, K20I, E35K, M36I, R41K, H69K, L89MCRF02_AG
Caron (2012)Gab013274Gab013274HQ541890None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
 Gab021293Gab021293HQ541903None   I13V, K14R, G17E, L19I, K20I, E35K, M36I, N37D, H69K, L89MCRF02_AG
Chamberland (2012)C406SC406SHQ267538None   I13V, G16E, K20I, E35K, M36I, R41K, H69K, L89MCRF02_AG
 C428SC428SHQ267553None   I13V, G16E, K20I, E35K, M36I, R41K, H69K, L89MCRF02_AG
 C446SC446SHQ267570None   I13V, I15V, G17E, K20I, E35K, M36V, N37D, R41K, I64M, H69K, V77I, L89MCRF02_AG
 C480SC480SHQ267587None   L10IV, I13V, G16GE, K20I, E35K, M36I, N37D, R41K, R57K, H69K, K70R, L89MCRF02_AG
 C498SC498SHQ267594None   I13V, G16E, K20I, E35K, M36I, P39S, R41K, L63P, H69K, V77I, L89MCRF02_AG
 C509SC509SHQ267599None   I13V, L19PS, K20I, E35K, M36I, N37D, R41K, I62IV, I64M, H69K, L89MCRF02_AG
 D330TD330THQ267626None   I13V, K14R, G17E, K20I, E35K, M36I, N37D, R41K, R57RK, H69K, K70R, L89MCRF02_AG
De Gascun (2012)IRL18888IRL18888JN622236None  K43TI13V, K14R, K20I, D25DY, E35K, M36V, R41K, H69K, L89MCRF02_AG
 IRL07975IRL07975JN622265None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
Delwart (2012)479-6750-2479-6750-2JN215060None   I13V, G16E, K20I, E35K, M36I, N37D, R41K, I64M, H69K, K70R, V77I, L89MCRF02_AG
Karlsson (2012)SE_115SE_115JQ698746None   I13V, K20I, E35K, M36I, N37E, R41K, H69K, L89MCRF02_AG
Somda (2012)49-218-2049-218-20HG529939None   I13V, K14KR, K20I, E35K, M36I, N37E, R41K, R57K, H69K, L89MCRF02_AG
Telan (2012)1106349311063493AB747465None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, K43R, H69K, T74S, L89M, T91ACRF02_AG
Youngpairoj (2012)cm1555cm1555DQ166397None   I13V, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
Antoniadou (2013)GR101GR101KF671811None   L10I, I13V, K14R, G16E, K20I, E35K, M36I, R41K, L63V, E65D, H69K, L89M, I93VCRF02_AG
Billong (2013)MR076MR076KF192252None   L10I, I13V, G16E, K20I, E35K, M36I, N37D, R57K, L63R, H69K, K70Q, V77VI, L89MCRF02_AG
 MR035MR035KF192154None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
 MR101MR101KF192161None   L10LI, I13V, K14KR, K20I, E35K, M36I, N37D, R41K, I64IM, H69K, L89MCRF02_AG
 MR074MR074KF192151None   I13V, K14KR, K20I, E35K, M36I, N37DE, R41K, H69K, L89MCRF02_AG
Frentz (2013)EHR-13777EHR-13777JX299767None   I13V, K20I, E35K, M36I, N37E, R41K, H69K, L89MCRF02_AG
 EHR-36060EHR-36060JX300143None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, H69K, L89MCRF02_AG
Imade (2013)ZZRJ002ZZRJ002KC755237None   I13V, K14R, K20I, E35K, M36I, R41T, K45R, L63P, H69K, L89MCRF02_AG