<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation E35K
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 4
Isolates 5
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG3333_w0 NFV1  I13V, I15V, K20I, E35K, M36I, R41I, K43R, L63LP, H69K, L89MCRF02_AG
Non-B Workgroup (2005)TK4015TK4015 NFV32M46ML I13V, K14R, G17E, K20I, E35K, M36I, R41K, I66IF, H69K, L89MCRF02_AG
Riddler (2008)RG60650RG60650w114 LPV114  I13V, G17E, K20I, E35K, M36I, R41K, L63P, H69K, L89MCRF02_AG
  RG60650w137 LPV137  Q2P, I13V, K14R, G17E, K20I, E35K, M36I, R41K, H69K, L89MCRF02_AG
Jenabian (2015)DR11DR11KF735822PINA  I13V, K14R, K20I, E35K, M36I, R41T, L63P, H69K, I72V, L89MCRF02_AG