<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation E35G
Rx PI-naive
IncludeMixtures No
References 38
Patients 51
Isolates 51
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Tscherning-Casper (2000)1952Pol1952PolAF268329None   I13V, K14R, L19P, K20I, E35G, M36I, R41K, H69K, L89MCRF02_AG
Thomson (2001)MT-X398MT-X398AY017455None   I3V, L10I, I13V, L19P, K20I, E35G, M36I, N37S, R41K, H69K, L89MCRF02_AG
Holguin (2002)AH_M1911AH_M1911AF247022None   L10I, I13A, K14R, K20I, A22T, E35G, M36I, R41K, C67H, H69K, V77I, L89M, I93LCRF02_AG
Eshleman (2004)ABB01ABB01AY444230None  V11IT12X, I13V, K14R, G16E, K20I, L33V, E35G, M36I, R41K, K43Q, H69K, K70R, I72V, L89MCRF02_AG
 ABB207ABB207AY444247None   I13V, K14R, K20R, E35G, M36I, N37D, R41K, H69K, L89ICRF02_AG
Kijak (2004)0190MA01CM.0190AY371145None   I13V, K14R, K20I, E35G, M36I, R41K, H69K, V77L, L89MCRF02_AG
Konings (2004)KF_Pat8200CM2140AY359764None   I13V, K20I, E35G, M36I, N37D, L63H, H69K, I72T, L89MCRF02_AG
Carr (2005)2103ND2103NDAY847440None   I13V, K14R, K20I, E35G, M36I, R41K, H69K, L89MCRF02_AG
Ndongmo (2006)CM189CBN_CM189DQ394137None   I13V, K14R, L19P, K20I, E35G, M36I, R41K, H69K, L89M, I93LCRF02_AG
Vessiere (2006)AV_M4091NAV_M4091NDQ297190None   I13V, K14R, K20I, E35G, M36I, R41K, I64M, H69K, L89MCRF02_AG
Holguin (2007)626182626182EF583291None   L10I, T12M, I13V, Q18QL, L19P, K20I, E35G, M36I, N37NS, R41K, L63PS, C67Y, H69K, L89MCRF02_AG
 626858626858EF583293None   I13V, K14R, K20I, E34V, E35G, M36I, R41K, H69K, L89M, I93LCRF02_AG
von Wyl (2007)1125876156EF449921None   I13V, K14R, K20I, E35G, M36I, N37D, R41K, H69K, V77I, L89MCRF02_AG
Caron (2008)1598Gab1598PEU556463None   I13V, K14R, I15V, G16E, K20I, E35G, M36I, P39L, H69K, L89MCRF02_AG
 1177Gab1177PEU556465None   L10I, I13V, G16E, K20I, E35G, M36I, R41K, H69Q, V75I, L89MCRF02_AG
Delgado (2008)GH_017GH_017EU177894None   I13V, K14R, G16E, K20I, E35G, M36I, R41K, H69K, K70E, V77VI, L89MCRF02_AG
Derache (2008)BKO-1015BKO-1015EU330709None   I13V, K14R, G17E, K20I, E35G, M36I, L63P, H69K, V77I, P79S, L89MCRF02_AG
Palacios (2008)4117541175 None  V11IT12K, I13V, K20I, E35G, M36I, N37D, R41K, H69K, L89MCRF02_AG
Aghokeng (2009)DC1_0074DC1_0074GU191647None   I13V, K14KI, L19S, K20I, E35G, M36I, N37ND, R41K, K43R, H69K, K70R, V77L, L89MCRF02_AG
Ayouba (2009)TE10030TE10030PRGQ351703None   I13V, K14R, L19P, K20I, E35G, M36I, N37S, R41K, H69K, L89MCRF02_AG
Bartolo (2009)SNS4001AOSNS40EU068301None   I13V, K14R, G16E, K20I, E35G, M36I, N37G, P39S, R41K, H69K, L89MCRF02_AG
Hawkins (2009)Q192ZZQ192FJ931200None   I13V, K14R, K20I, E35G, M36I, R41K, L63P, G68E, H69K, K70R, V77I, L89MCRF02_AG
Vercauteren (2009)pt15284101464872GQ399496None   L10I, I13V, K14RS, G16E, K20I, E35G, M36I, R41K, H69K, K70R, L89MCRF02_AG
 pt11656185176216GQ399859None   L10V, I13V, L19P, K20I, E35G, M36I, N37D, R41K, Q61H, H69K, L89MCRF02_AG
Yaotse (2009)HT15206TG.HT152FM955740None   I13V, K20I, E35G, M36I, N37S, P39S, R41K, R57K, L63P, H69K, V77I, L89MCRF02_AG
 HT17006TG.HT170FM955746None  V11IL10V, I13V, G16E, L19P, K20I, E35G, M36I, R41K, L63S, H69K, I72IV, V77I, L89MCRF02_AG
 HT24706TG.HT247FM955755None   T4P, Q7D, L10V, T12A, I13V, K14R, G16E, K20I, E35G, M36I, R41K, R57K, L63H, H69K, P79S, L89MCRF02_AG
Diop-Ndiaye (2010)928hald928haldFN599761None   I13V, K20I, E35G, M36I, R41K, H69K, V77VI, L89IMCRF02_AG
Djoko (2010)GQ06108GQ061FN557331None   I13V, K14R, G16E, K20I, E35G, M36I, R41K, H69K, I72L, L89MCRF02_AG
Soares (2010)CM04_042CM04_042GU366108None   I13V, K14R, K20I, E35G, M36I, R41K, I64M, H69K, L89MCRF02_AG
Yebra (2010)22414805SP0224148FJ481701None   I13V, K14R, K20I, E35G, M36I, R41K, I62V, L63I, H69K, V77I, L89MCRF02_AG
Aghokeng (2011)SK2047-M12SK2047-M12HQ864447None   I13V, K14DN, G16E, K20I, E35G, M36I, R41K, I64M, E65N, H69K, L89MCRF02_AG
Dagnra (2011)08TG.C701208TG.C7012FR715288None   T12N, I15V, G16E, K20I, E35G, M36I, N37NS, R41K, R57K, L63Q, H69K, K70R, V77I, L89MCRF02_AG
Hamers (2011)300661CP076300661HM120052None   L10V, I13V, K14R, G17E, K20I, E35G, M36I, R41K, R57K, E65D, H69K, K70R, V77I, L89MCRF02_AG
 CP076303527CP076303527HQ994008None   I13V, K20I, E35G, M36I, P39Q, R41K, R57RK, Q61E, L63LP, E65D, H69K, V77I, L89MCRF02_AG
 CP076305221CP076305221HQ994154None   I13V, L19P, K20I, E35G, M36I, R41K, H69K, K70R, V77VI, L89MCRF02_AG
Caron (2012)Gab014265Gab014265HQ541899None   T12A, I13V, K20I, E35G, M36I, R41K, H69K, I72F, L89MCRF02_AG
 Gab091163Gab091163JN705006None   I13A, G16E, K20I, E35G, M36I, R41K, L63S, C67Y, H69K, L89MCRF02_AG
Chamberland (2012)C424SC424SHQ267550None   I13V, I15V, K20I, E35G, M36I, N37S, R41K, L63P, H69K, V77I, P79S, L89MCRF02_AG
 C450SC450SHQ267572None   I13V, K20I, E35G, M36I, N37S, R41K, R57K, I62V, G68E, H69R, V77I, L89MCRF02_AG
 C460SC460SHQ267578None   L10I, I13V, K14R, G16GW, K20I, E35G, M36I, N37S, R41K, L63P, C67D, H69K, P79S, L89MCRF02_AG
De Gascun (2012)IRL27388IRL27388JN622269None   I13V, K14R, L19P, K20I, E34EA, E35G, M36I, L38LI, R41K, L63LP, H69K, K70KR, L89MCRF02_AG
 IRL23061IRL23061JN622348None   T12TP, I13V, K20I, E35G, M36I, N37NS, R41K, R57RS, H69K, P79S, L89M, Q92QHCRF02_AG
Ugbena (2012)1-1-1131-1-113JX084053None   G16E, K20I, E35G, M36I, R41K, H69K, K70E, L89MCRF02_AG
Antoniadou (2013)GR123GR123KF671832None   L5F, Q7QH, I13A, K14R, G16E, K20V, E35G, M36I, R41K, L63A, H69K, K70R, L89M, Q92QR, F99FLCRF02_AG
Billong (2013)MR107MR107KF192133None   L10LI, I13V, K20I, E35G, M36IV, N37D, R41RK, L63P, H69KQ, V77L, L89MCRF02_AG
Kebe (2013)SN2512HALDSN2512HALDHM002502None   I13V, K14R, L19P, K20I, E35G, M36I, N37D, R41K, I62V, H69K, K70R, V77L, L89MCRF02_AG
Nii-Trebi (2013)775775AB751454None   I13V, I15V, K20I, E35G, M36I, P39Q, R41K, H69K, V77I, L89MCRF02_AG
 KF66KF66AB751478None   I13V, K20I, E35G, M36I, N37S, P39Q, R41K, I64L, H69K, K70E, V77I, L89MCRF02_AG
Temereanca (2013)SR31SR31JX966508None   I13A, K14R, K20I, E35G, M36I, R41K, I64V, H69KCRF02_AG
Meixenberger (2014)09-0284609-02846KJ771075None   I13V, K14R, K20I, E35G, M36I, N37D, R41K, H69K, K70R, V77I, L89MCRF02_AG