<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation K20R
Rx PI-naive
IncludeMixtures No
References 40
Patients 74
Isolates 75
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cornelissen (2000)MC93GH05MC93GH05AF212277None   I13V, G16E, K20R, E35D, M36I, N37D, G40X, R41K, L63V, G68E, H69K, K70R, L89I, T91V, I93LCRF02_AG
Tscherning-Casper (2000)3987Pol3987PolAF268336None   I13V, K14KR, K20R, M36I, R41K, H69K, L89MCRF02_AG
Eshleman (2001)SE816SE816AF388160None   L10V, I13V, K20R, M36I, R41K, L63PCRF02_AG
Fonjungo (2002)CM109CM109AY051220None   I13V, K14R, K20R, M36I, N37D, R41K, H69K, L89M, I93LCRF02_AG
Gibb (2002)DMG9696_w27 None   I13V, K20R, M36I, N37ND, R41K, H69K, L89MCRF02_AG
Pandrea (2002)IP_97CIRMF5897CIRMF58AY140641None   I13V, K20R, E35D, M36I, N37D, R41K, L63T, I64M, H69K, I72T, L89MCRF02_AG
Tebit (2002)99CMLB999CMLB9AF355306None   I13V, K20R, M36I, R41K, L63P, H69K, L89MCRF02_AG
Vergne (2002)LV11LLV11LAJ313413None   I13V, K20R, M36I, R41K, H69K, L89MCRF02_AG
Toni (2003)TTDdp54TTDdp54AY207698None   I13V, K20R, M36I, R41K, L63P, H69K, L89MCRF02_AG
 TTDpci136TTDpci136AY207741None   I13V, K14R, K20R, M36I, N37D, R41K, H69K, L89MCRF02_AG
 TTDpci144TTDpci144AY207713None   L10I, I13V, G16E, K20R, E35D, M36I, R41K, R57K, H69Q, L89MCRF02_AG
Eshleman (2004)ABB207ABB207AY444247None   I13V, K14R, K20R, E35G, M36I, N37D, R41K, H69K, L89ICRF02_AG
Carr (2005)4217STN4217STNAY847374None   I13V, K14R, K20R, E35D, M36I, N37S, R41K, H69K, K70Q, L89MCRF02_AG
 4286STN4286STNAY847375None   I13V, K20R, E35D, M36I, N37S, R41K, H69K, K70Q, L89MCRF02_AG
 2685ND2685NDAY847443None   I13V, K20R, E35D, M36I, R41K, H69K, L89MCRF02_AG
Marechal (2006)JF_090JF_090DQ443686None   L10V, I15V, L19M, K20R, E35D, M36I, R41K, H69Q, L89MCRF02_AG
Ndongmo (2006)CM7CBN_CM7DQ394109None   I13V, K20R, M36I, R41K, H69K, L89M, I93LCRF02_AG
 CM171CBN_CM171DQ394168None   L10V, I15V, G16A, L19M, K20R, R41K, D60E, Q61G, L63I, C67E, H69K, V77I, L89M, I93LCRF02_AG
 CM386CBN_CM386DQ394177None   L10V, I15V, G16A, L19M, K20R, R41K, D60E, Q61G, L63I, C67E, H69K, V77I, L89M, I93LCRF02_AG
Razafindratsimandresy (2006)RR_MAD-MO055MAD-MO055DQ345030None   L19Q, K20R, L33V, M36I, R57K, I62V, L63N, I64V, H69Y, I72VCRF02_AG
Vidal (2006)NV_KS07202.KS072AM041010None   G16E, K20R, E35D, M36I, P39S, R41K, K45R, I62V, L63T, E65D, H69K, I72T, L89MCRF02_AG
Derache (2007)12391239EF064491None   I13V, K20R, L23H, M36I, R41K, L63S, H69K, L89MCRF02_AG
 12681268EF064507None   I13V, K20R, M36I, R41K, H69K, L89ICRF02_AG
 12841284EF064521None   I13V, K14R, K20R, M36I, N37D, R41K, H69K, K70R, L89M, I93LCRF02_AG
 13411341EF064544None   I13V, K14R, K20R, M36I, N37D, R41K, Q61H, H69K, K70R, L89MCRF02_AG
Delgado (2008)GH_019GH_019EU177896None   I13V, K20R, M36I, R41K, L63V, I64M, H69K, L89MCRF02_AG
 GH_020GH_020EU177897None   T12TI, I13A, K20R, A22V, M36I, N37D, R41K, L63LHP, H69K, K70R, L89MCRF02_AG
 GH_049GH_049EU177921None   I13V, K14R, K20R, M36I, N37D, R41K, I64IL, H69K, L89MCRF02_AG
 GH_071GH_071EU177936None   I13V, K20R, M36I, R41K, I64IV, H69K, L89MCRF02_AG
 GH_075GH_075EU177939None   L10V, I13V, K14R, K20R, M36I, R41K, L63V, H69K, L89MCRF02_AG
 GH_081GH_081EU177945None   L10V, I13V, K20R, M36I, N37D, R41K, I64L, H69K, L89MCRF02_AG
 GH_167GH_167EU178006None   I13V, K14R, K20R, E35D, M36I, R41K, H69K, L89MCRF02_AG
 GH_176GH_176EU178013None   I13V, G16E, K20R, E35D, M36I, R41K, L63S, H69K, K70R, L89MCRF02_AG
 GH_204GH_204EU178035None   I13V, K20R, M36I, R41K, R57K, L63P, H69K, L89MCRF02_AG
Derache (2008)BKO-949BKO-949EU330680None   L10V, I13V, K14R, G16A, L19Q, K20R, M36I, N37D, R41K, H69K, L89MCRF02_AG
 BKO-1020BKO-1020EU330712None   T12A, I13V, K20R, M36I, N37D, R41K, L63P, H69K, L89MCRF02_AG
 SGO-37SGO-37EU330781None   I13V, K14R, K20R, M36I, N37D, R41K, K43R, R57K, H69K, L89MCRF02_AG
 SGO-68SGO-68EU330811None   L10V, I13V, K20R, M36I, N37D, R41K, H69K, K70R, L89MCRF02_AG
 SGO-73SGO-73EU330816None  L33FL10V, I13V, K14R, G16E, K20R, M36I, N37E, P39S, R41K, R57K, L63A, E65D, H69Q, L89M, I93LCRF02_AG
Holguin (2008)SP94-246975SP94-246975EU342781None   L10V, I13V, G16E, K20R, E35D, M36I, P39S, R41K, K45R, L63T, E65D, H69K, L89MCRF02_AG
Ndembi (2008)CMYD-404CMYD-4DQ990379None   I13V, K14R, K20R, M36I, R41K, H69K, L89MCRF02_AG
 CMYD-8304CMYD-83DQ990443None   K20R, E21K, M36I, R41K, E65K, G68E, H69K, L89MCRF02_AG
Nyombi (2008)TMS346TMS346EU251879None   I13V, K14R, G16E, K20R, E35D, M36I, R41K, H69K, L89MCRF02_AG
Rosen-Zvi (2008)103p1-1 None   I13V, K14R, K20R, M36I, N37D, R41K, L63P, H69K, K70R, L89MCRF02_AG
Aghokeng (2009)CDL20CDL20GU191608None   I13V, G16E, K20R, M36I, P39Q, R41K, H69K, L89MCRF02_AG
Cuevas (2009)P1423P1423.1EU822650None   L10V, I13V, K20R, M36I, N37D, R41K, H69K, L89MCRF02_AG
Hawkins (2009)Q236ZZQ236FJ931226None   I13V, K20R, M36I, N37S, R41K, H69K, L89ICRF02_AG
 Q959ZZQ959FJ931272None   I13V, K20R, M36I, N37D, R41K, I64L, H69K, L89MCRF02_AG
 Q958ZZQ958FJ931326None   I13V, K20R, M36I, N37Q, P39D, R41K, L63LP, H69K, L89MCRF02_AG
 R382ZZR382FJ931426None   I13V, K14R, K20R, M36I, R41K, I62V, L63S, I64M, H69K, L89MCRF02_AG
Tebit (2009)TR142TR142FJ577296None   L10V, I13V, K20R, M36I, N37D, R41K, H69K, L89MCRF02_AG
Vercauteren (2009)pt19661492483967GQ399058None   I13V, K14R, G16R, K20R, M36I, R41K, H69K, G86V, L89MCRF02_AG
 pt17652793001530GQ399259None   L10V, I13V, K14R, K20R, M36I, N37D, R41K, H69K, L89MCRF02_AG
Diop-Ndiaye (2010)L140L140FN599728None   L10V, I13V, K20R, M36I, R41K, H69K, L89MCRF02_AG
 939hald939haldFN599765None   I13V, K14R, K20R, M36I, N37D, R41K, H69K, L89MCRF02_AG
Yebra (2010)26979205SP0269792FJ481704None   L10V, I13V, K20R, M36I, N37S, R41K, H69K, L89MCRF02_AG
Aghokeng (2011)HJ1958HJ1958JN639476None   I13V, K14R, K20R, M36I, R41K, H69K, L89MCRF02_AG
 HJ1883HJ1883JN639486None   L10LV, I13V, K14KR, L19LP, K20R, M36I, N37ND, R41K, H69K, K70R, L89MCRF02_AG
Dagnra (2011)08TG.E504408TG.E5044FR715280None  L33FI13V, K14R, L19P, K20R, M36I, N37D, R41RK, L63T, H69K, K70R, L89MCRF02_AG
Fokam (2011)CIRCB-3241CIRCB-3241JQ796147None   I13V, K14R, K20R, M36I, N37D, R41K, H69K, K70R, L89I, N98KCRF02_AG
Hamers (2011)CP076301586CP076301586HQ993624None   K20R, E35D, M36I, R41K, L63T, H69K, L89M, T91V, I93LCRF02_AG
 CP076301629CP076301629HQ993778None   I13V, K14R, G16E, K20R, E35D, M36I, R41K, L63T, G68E, H69K, L89IM, T91V, I93LCRF02_AG
 CP076304194CP076304194HQ993899None   T12P, I13V, K14R, G16E, K20R, E35D, M36I, N37D, R41K, L63S, H69K, K70KR, V77I, L89M, I93LCRF02_AG
 CP076305166CP076305166HQ994119None   I13A, K20R, M36I, N37E, H69K, L89MCRF02_AG
Chamberland (2012)C517SC517SHQ267606None   I13V, K14KR, K20R, M36I, N37D, R41K, H69K, K70R, L89MCRF02_AG
Somda (2012)8A-145-238A-145-23HG529933None   I13V, K20R, M36I, R41K, H69K, L89MCRF02_AG
Youngpairoj (2012)cm1680cm1680DQ166408None   I13V, K14R, K20R, M36I, N37D, R41K, H69K, L89MCRF02_AG
Billong (2013)MR053MR053KF192196None   I13V, K20R, M36I, R41K, H69K, L89MCRF02_AG
 MR122MR122KF192164None   I13V, K14KR, G16E, K20R, E35D, M36I, N37NADT, R41K, H69K, K70KR, L89MCRF02_AG
 MR045MR045KF192185None  L33FI13V, K14R, K20R, M36I, N37E, P39A, R41K, K43R, I62V, L63P, H69K, K70R, L89MCRF02_AG
 MR041MR041KF192155None   I13LV, K14R, K20R, L24LPS, D25DG, M36I, N37D, R41K, H69K, L89MCRF02_AG
  MR041KF192169None   I13V, K14R, K20R, M36I, N37D, R41K, H69K, L89MCRF02_AG
Frentz (2013)EHR-42510EHR-42510JX300256None   I13V, K14R, K20R, E35D, M36I, N37D, R41K, H69K, L89MCRF02_AG
Hassan (2013)RS09000931RS09000931HQ441673None   I13V, G16E, K20R, E35D, M36I, R41K, L63T, G68E, H69K, K70R, V82I, L89M, T91V, I93LCRF02_AG
Van Zyl (2013)10292136KC423643None   L10I, I13V, K14R, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, H69K, L89MCRF02_AG