<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation I13A
Rx >= 1 PI
IncludeMixtures No
References 12
Patients 27
Isolates 29
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Holguin (2003)SP_LP38SP_LP38AF455630PINA  I13A, K20I, M36I, N37S, R41K, H69K, L89MCRF02_AG
Montes (2004)MB_patGONO00_GONO705AJ577902NFV66  I13A, K14R, K20I, M36I, R41K, H69K, L89MCRF02_AG
Non-B Workgroup (2005)PL1692571340 NFV, UnknownNAM46I, I84V, L90ML33LI, L89VL10V, I13A, K14KR, K20IV, A22AV, E35EG, M36I, R41RK, K55KR, L63P, I66FV, H69K, K70R, P79PACRF02_AG
Baxter (2006)12-31973197-30821DQ876738PINAI54V, V82AL89VL10V, I13A, K14R, K20I, A22V, M36I, R41K, I62V, H69K, G73D, T74S, T91TSCRF02_AG
  3197-40128DQ876116PI, RTV, TPV>23I54V, V82AL89VL10V, I13A, K14R, K20I, A22V, L33L_L, M36I, R41K, I62V, H69K, G73D, T74S, T91TSCRF02_AG
 48-30363036-30310DQ877947PINAM46L, I54V, I84V, L90ML33I, L89VL10I, T12A, I13A, L19P, K20V, A22V, M36I, R41K, I66F, H69K, K70R, A71V, Q92KCRF02_AG
 48-32243224-30624DQ878131PINAM46I, I47IV, L76V, I84VL33LI, Q58EL10I, I13A, K20I, A22V, M36I, R41K, L63P, I66F, H69K, K70R, L89I, T91SCRF02_AG
 48-32833283-30916DQ878190PINAM46I, I54M, L76V, I84VG73A, L89VL10I, I13A, K14KR, L19LI, K20I, L33V, M36I, R41K, K55R, R57RK, D60E, L63P, I66F, H69KCRF02_AG
 48-40814081-30228DQ878310PINAM46L, I54V, I84V L10V, I13A, K14R, K20I, A22V, E35D, M36I, N37S, R41K, Q61H, I66F, H69K, K70R, P79S, L89I, T91TSCRF02_AG
 48-41674167-30423DQ878400PINAM46L, I54V, I84V L10I, I13A, L19P, K20I, A22V, E35D, M36I, N37S, R41K, D60E, I66F, H69K, A71V, L89I, T91S, Q92KCRF02_AG
  4167-40203DQ878401PI, RTV, TPV>41M46L, I54V, I84V L10I, I13A, A22V, E35D, M36I, N37S, R41K, D60E, I66F, H69K, A71V, L89I, T91S, Q92KCRF02_AG
 48-71247124-30902DQ878967PINAM46I, I47V, L76V, I84VQ58EL10I, I13A, K14IR, L19P, K20I, M36I, N37D, R41K, K55KR, L63P, H69K, K70R, L89ICRF02_AG
Laurent (2006)CK2-4702CM-47AM279442IDV43  T12K, I13A, K14R, K20I, M36I, R41K, H69K, L89MCRF02_AG
Charpentier (2011)CR-34CR-34FJ688240PINAM46I, I54V, I84V L10I, I13A, K14R, K20I, M36I, R41K, K43R, H69K, K70R, A71I, P79S, L89T, Q92K, I93MCRF02_AG
Kouri (2012)CU294-10CU294-10JQ585376PINAM46L, I54V, I84VQ58E, L89VI13A, L19P, K20I, A22V, L33V, E35D, M36I, N37D, I62IV, L63P, I66F, H69K, A71V, T74A, Q92K, I93IVCRF02_AG
 CU344-10CU344-10JQ585386PINAM46L, I54V, I84VQ58EI13A, K20I, E35N, M36I, Q61QR, L63P, H69K, K70R, A71V, L89TCRF02_AG
Rawizza (2013)PJ9681PJ9681KF241511LPV I54V, V82AL89VL10V, I13A, K14R, I15V, K20I, A22V, E35D, M36I, R41K, Q61H, L63P, H69KCRF02_AG
 LN0911LN0911KF241494LPV   I13A, K20I, E35G, M36I, R41K, H69K, L89MCRF02_AG
 LN4321LN4321KF241489LPV I54V, V82FQ58E, N83DL10V, T12M, I13A, K14KR, G16A, L19P, K20I, A22V, E35N, M36I, N37D, R41RK, Q61QH, L63P, H69K, A71V, L89I, I93MCRF02_AG
 PJ0771PJ0771KF241503LPV   I13A, K14R, I15IV, K20I, M36I, N37E, R41K, K43R, L63P, H69K, K70R, L89MCRF02_AG
 PJ2149PJ2149KF241459LPV M46LV, I54V, L76V, V82M, L90ML89IVT4S, L10IV, I13A, K20IV, A22V, E35D, M36I, N37DE, Q61E, I62V, L63P, C67F, H69K, A71I, I72L, P79A, T91S, Q92QKCRF02_AG
 LN0239LN0239KF241471LPV   I13A, K20I, E35D, M36I, N37ND, H69K, L89MCRF02_AG
 PJ9581PJ9581KF241512LPV M46MI, L76LV I13A, K14R, G16E, K20I, M36I, P39A, R41K, I62V, L63S, H69K, K70R, L89ICRF02_AG
Thiam (2013)495-HALD495-HALDJN673647LPV M46I, I47V, I54V, I84V, L90ML33I, L89VT4S, L10I, T12M, I13A, K14M, L19P, K20I, A22V, E35D, M36I, N37D, R41RK, R57K, Q61QH, I62IV, L63P, I66F, H69K, A71VCRF02_AG
Grossman (2014)501501 LPV52  I13A, K14R, K20I, M36I, P39PL, R41K, L63LP, H69K, I72M, L89ICRF02_AG
Diaz (2015)RenG14852RenG14852KT745880PINA  I13A, K20I, M36I, R41K, H69K, K70R, L89MCRF02_AG
 RenG12952RenG12952KT743980PINAM46I, I54V, V82A, L90ML33I, L89VL10V, I13A, K14R, K20V, E35G, M36I, R41N, K55R, I62V, I66F, H69K, A71T, T74SCRF02_AG
 RenG11942RenG11942KT742970PINAL90ML89VL10V, I13A, K14R, K20I, E35G, M36I, N37S, R41K, I62V, I66F, H69K, K70R, A71TCRF02_AG
Abdellaziz (2016)1494014940KT339037PINAM46I, I47V, L76V, I84VF53FLL10I, T12S, I13A, K14R, I15V, K20I, M36I, R41K, I62V, I66F, H69K, L89ICRF02_AG