<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation L10V
Rx >= 1 PI
IncludeMixtures No
References 12
Patients 32
Isolates 37
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M15M15AY010377PINA L89VL10V, I13V, K14R, L19P, K20I, E35N, M36I, N37D, R41K, H69K, T74SCRF02_AG
 NY_M47M47AY010411IDV   L10V, I13V, L19P, K20I, M36I, H69K, L89MCRF02_AG
 NY_M65M65AY010428PINA L89VL10V, I13V, K14R, L19LP, K20I, E35N, M36I, N37D, R41K, H69K, T74SCRF02_AG
Snoeck (2002)BE2BE2AF338979IDV, SQV, RTV, NFV109V32I, I47V, G48V, I54V, V82ATF53FL, L89VL10V, I13V, L19IT, K20I, M36I, R41K, K55H, L63P, C67S, H69R, A71IVCRF02_AG
Vergne (2003)VL98SN65HALD00SN65AJ583751IDV  L89VL10V, I13V, L19P, K20I, M36I, R41K, H69K, K70RCRF02_AG
Montes (2004)MB_patSCHE02_SCHE715AJ578156IDV60  L10V, I13V, G16E, K20I, M36I, R41K, L63H, H69K, K70R, I72V, L89M, I93LCRF02_AG
 MB_patKES01_KES716AJ577920NFV136M46I, L90ML89VL10V, I13V, K14R, G16E, K20I, E35D, M36I, R41K, H69K, K70R, T74S, V75ICRF02_AG
 MB_patFEU02_FEU726AJ577889IDV, SQV, RTV190I84V L10V, I13V, K14R, L19P, K20I, E21D, L33V, M36I, N37D, R41K, F53Y, I64L, H69K, K70R, T74S, L89MCRF02_AG
 MB_patKON00_KON723AJ577921IDV, NFV117I54V L10V, I13V, K14R, K20I, E35G, M36I, R41K, I64M, H69K, A71V, L89ICRF02_AG
Non-B Workgroup (2005)PL1692558358AY900968NFV M46I, L90ML89VL10V, I13V, K20V, M36I, R41K, L63P, H69K, K70RCRF02_AG
  71340 NFV, UnknownNAM46I, I84V, L90ML33LI, L89VL10V, I13A, K14KR, K20IV, A22AV, E35EG, M36I, R41RK, K55KR, L63P, I66FV, H69K, K70R, P79PACRF02_AG
 PL3780663403AY901079SQV   L10V, I13V, K14R, G16E, K20I, E35D, M36I, R41K, H69K, V77VI, L89MCRF02_AG
 PL2828567988AY901085IDV, ATV I84V, L90ML33LF, L89VL10V, I13V, K14R, G16E, K20IM, E35EG, M36I, R41K, Q61H, C67Y, G68D, H69K, A71T, I72RCRF02_AG
  65163 IDV, ATV, UnknownNAV82VA, I84IV, L90ML33F, K43KT, L89VL10V, I13V, K14R, G16E, K20IM, E35G, M36I, R41K, Q61H, C67Y, G68GE, H69Q, I72RCRF02_AG
 PL3692269089AY901091NFV87L90M L10V, T12S, I13V, K14R, G16E, K20I, E35G, M36I, P39S, R41K, I62IV, I66F, H69K, K70R, L89MCRF02_AG
 IL32IL32cAY901181NFV67M46I, N88S L10V, I13V, K20I, M36I, P39L, R41K, I62V, L63P, H69K, L89MCRF02_AG
 PL3191579867 IDV, RTV155 V11VIP1PS, L10V, I13V, K14R, G16E, K20I, M36I, R41K, I64IV, H69K, K70R, I72V, L89MCRF02_AG
  95985 IDV, RTV206 V11VIL10V, I13V, K14R, G16E, L19LP, K20I, M36I, R41K, H69K, K70R, I72V, L89MCRF02_AG
 PL3275105576 SQV282  L10V, I13V, K20I, M36I, R41K, H69K, T74S, V75I, L89MCRF02_AG
 PL3504797181 IDV, NFV337M46I, L90ML89VL10V, I13V, K14KR, L19LP, K20I, E35G, M36I, N37E, R41K, I62V, H69K, K70R, T74SCRF02_AG
 PL53865102930 IDV226  L10V, I13V, K14R, G16E, L19P, K20V, M36I, R41K, H69K, L89MCRF02_AG
Baxter (2006)12-31973197-30821DQ876738PINAI54V, V82AL89VL10V, I13A, K14R, K20I, A22V, M36I, R41K, I62V, H69K, G73D, T74S, T91TSCRF02_AG
  3197-40128DQ876116PI, RTV, TPV>23I54V, V82AL89VL10V, I13A, K14R, K20I, A22V, L33L_L, M36I, R41K, I62V, H69K, G73D, T74S, T91TSCRF02_AG
 48-12441244-30527DQ877767PINAM46L, I54V, V82A, I84VV11VI, L33F, K43T, F53LT4A, L10V, I13V, G16A, L19P, K20M, E21A, E35D, M36L, K55R, Q61H, L63P, H69K, T74AS, L89I, T91SCRF02_AG
 48-40814081-30228DQ878310PINAM46L, I54V, I84V L10V, I13A, K14R, K20I, A22V, E35D, M36I, N37S, R41K, Q61H, I66F, H69K, K70R, P79S, L89I, T91TSCRF02_AG
Seyler (2007)004CS_004 NFV, IDV196  L10V, I13V, K14R, G16E, K20I, M36I, R41K, H69K, K70R, L89MCRF02_AG
 195CS_195 IDV111  L10V, I13V, K14R, G16E, K20I, E35D, M36I, R41K, I62IV, H69K, K70KR, T74TS, L89MCRF02_AG
 282CS_282 NFV, IDV150L90ML89VL10V, T12TK, I13V, L19P, K20I, E35G, M36I, N37ND, Y59YC, L63P, E65EK, H69K, K70R, A71TCRF02_AG
 292CS_292 IDV101 L33IL10V, T12A, I13V, K14KR, G16E, K20R, M36I, R41K, L63T, H69K, K70R, L89MCRF02_AG
 474CS_474 NFV, IDV177 V11VIL10V, T12PQ, I13V, K14IR, I15IV, G16E, L19P, K20I, M36I, R41K, K43KR, L63LH, H69K, K70KR, I72IT, L89MCRF02_AG
von Wyl (2007)1205327019EF449829PINAL90M L10V, I13V, K14R, I15V, K20I, E35G, M36I, R41K, L63P, G68E, H69R, A71T, L89ICRF02_AG
Rosen-Zvi (2008)104p1-2 LPV85V82AN83DL10V, I13V, K14R, K20R, M36I, N37D, R41K, Q61H, H69K, K70R, L89ICRF02_AG
  05p1-3 LPV, RTV, APV140M46I, V82A, I84VN83DL10V, I13V, K14R, K20R, A22V, M36I, N37D, R41K, Q61H, H69K, K70R, L89ICRF02_AG
 4600p46-1 RTV, SQV, NFV, APV141M46MIL, I54V, V82M, I84V, L90ML33F, Q58EL10V, T12V, I13IV, K14KR, I15V, K20R, E35D, M36I, N37E, R41K, R57K, L63P, H69K, L89ICRF02_AG
Sylla (2008)A4197A4197_C2DQ991640IDV   L10V, I13V, G16E, K20I, M36I, P39L, L63S, H69K, L89ICRF02_AG
Knops (2010)ID0462ID0462-GT2GU271157LPV105M46I, L76V L10V, T12K, I13V, K14R, G16E, L19I, K20I, M36I, R41K, H69K, L89MCRF02_AG
Charpentier (2011)2CP 001-032 Unknown, LPVNA L89VL10V, I13V, I15V, L19KR, K20I, E35G, M36I, N37ND, R41K, I62IV, L63P, H69K, K70N, A71T, T74TSCRF02_AG