<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation L10I
Rx >= 1 PI
IncludeMixtures No
References 17
Patients 38
Isolates 40
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Si-Mohamed (2000)AS_FANAS_FANAF199275IDV I84V, L90ML89VL10I, I13V, L19P, K20I, M36I, N37S, R41K, L63P, H69K, K70R, A71V, I72MCRF02_AG
Montes (2004)MB_patALC02_ALC723AJ577727NFV, SQV, RTV91I84V, L90M L10I, I13V, K20I, E35D, M36I, R41K, K43R, L63P, H69K, A71V, L89ICRF02_AG
Non-B Workgroup (2005)TK2008TK2008 RTV, IDV, NFV73  L10I, I13V, K20I, M36I, R41K, L63P, C67S, H69K, K70R, L89MCRF02_AG
 TK3002TK3002 SQV, RTV105  L10I, I13V, L19P, K20I, M36I, R41K, H69K, K70R, L89MCRF02_AG
  TK3002a SQV, RTV, IDV207  L10I, I13V, L19P, K20I, E35ED, M36I, R41K, H69K, K70R, L89MCRF02_AG
Weber (2005)30239393023939AY677492APV, LPV239M46I, L76V, V82F, I84C L10I, I13V, G16E, K20I, E35D, M36I, N37NK, R41K, L63M, H69K, K70R, T74S, L89MCRF02_AG
Baxter (2006)48-30363036-30310DQ877947PINAM46L, I54V, I84V, L90ML33I, L89VL10I, T12A, I13A, L19P, K20V, A22V, M36I, R41K, I66F, H69K, K70R, A71V, Q92KCRF02_AG
 48-30903090-30925DQ877999PINAM46I, I47V, I54V, V82C, I84VV11I, L33I, K43T, F53FLL10I, T12M, I13V, K14R, L19P, K20I, A22V, M36I, R41K, K55R, H69K, K70R, I72V, T74S, L89I, T91SCRF02_AG
 48-32243224-30624DQ878131PINAM46I, I47IV, L76V, I84VL33LI, Q58EL10I, I13A, K20I, A22V, M36I, R41K, L63P, I66F, H69K, K70R, L89I, T91SCRF02_AG
 48-32833283-30916DQ878190PINAM46I, I54M, L76V, I84VG73A, L89VL10I, I13A, K14KR, L19LI, K20I, L33V, M36I, R41K, K55R, R57RK, D60E, L63P, I66F, H69KCRF02_AG
 48-41674167-30423DQ878400PINAM46L, I54V, I84V L10I, I13A, L19P, K20I, A22V, E35D, M36I, N37S, R41K, D60E, I66F, H69K, A71V, L89I, T91S, Q92KCRF02_AG
  4167-40203DQ878401PI, RTV, TPV>41M46L, I54V, I84V L10I, I13A, A22V, E35D, M36I, N37S, R41K, D60E, I66F, H69K, A71V, L89I, T91S, Q92KCRF02_AG
 48-50755075-30807DQ878585PINAM46L, G48T, I54V, V82A, I84VV11VILL10I, T12TS, I13V, K14R, L19P, K20I, E35D, M36I, N37NS, R41K, Q61H, H69K, T74S, L89I, T91SCRF02_AG
 48-71247124-30902DQ878967PINAM46I, I47V, L76V, I84VQ58EL10I, I13A, K14IR, L19P, K20I, M36I, N37D, R41K, K55KR, L63P, H69K, K70R, L89ICRF02_AG
Laurent (2006)CK22-7503CM2-75AM279460IDV63  L10I, I13V, K14R, L19P, K20I, M36I, R41K, L63S, L89MCRF02_AG
Seyler (2007)179CS_179 IDV119 V11IL10I, I13V, G16E, K20I, M36I, N37ND, R41K, L63T, H69K, K70KR, A71T, L89M, I93LCRF02_AG
 545CS_545 IDV170I84VL33I, L89VL10I, I13V, K14R, L19P, K20I, A22V, M36I, N37D, L38I, R41K, L63P, H69K, A71V, T74SCRF02_AG
von Wyl (2007)1105247133EF449805PINAN88S L10I, I13V, K14R, G16E, K20I, E35Q, M36I, R41K, R57K, H69K, T74S, L89MCRF02_AG
 105697505EF449819PINA  L10I, I13V, L19P, K20I, M36I, R41K, I64IV, H69K, K70R, L89MCRF02_AG
 15496611EF449962PINA V11VIL10I, I13V, K14KR, I15V, L19P, K20I, E21ED, M36I, N37D, R41K, H69Q, K70R, L89MCRF02_AG
Koyalta (2009)78TCHAD-78FJ688207IDV26  L10I, T12K, I13V, K14R, G16E, L19P, K20V, E35D, M36I, R41S, C67Y, H69K, L89MCRF02_AG
Charpentier (2011)CR-22CR-22FJ688228PINA N83DL10I, I13V, I15IV, K20I, E35KN, M36I, N37E, P39PQ, R41K, K45R, I62V, L63P, H69Q, I72IV, L89ICRF02_AG
 CR-25CR-25FJ688231PINAM46I, L76V, I84IV L10I, I13V, K20I, M36I, R41K, L63P, I66F, H69K, L89MCRF02_AG
 CR-34CR-34FJ688240PINAM46I, I54V, I84V L10I, I13A, K14R, K20I, M36I, R41K, K43R, H69K, K70R, A71I, P79S, L89T, Q92K, I93MCRF02_AG
Barber (2012)6078360783JQ361670LPV M46I, I84V L10I, I13V, G16E, Q18QK, L19LP, K20I, E35D, M36I, N37T, P39S, R41K, I62V, H69K, K70R, T74A, L89MCRF02_AG
Kouri (2012)CU1191-10CU1191-10JQ585353PINA L33LIT4N, L5F, R8G, L10I, T12A, I13V, K14R, K20I, E35D, M36I, R41K, H69K, L89MCRF02_AG
 CU40-11CU40-11JQ585473PINA  L10I, I13V, K14R, G17E, K20I, E35D, M36I, R41K, L63C, H69K, K70R, T74A, V82I, L89MCRF02_AG
 CU1288-10CU1288-10JQ585421PINAM46I, I54L, I84VV11I, L33F, Q58EL10I, I13V, K14R, I15V, G16E, L19P, K20V, E35N, M36I, N37D, K55R, R57RK, Q61H, L63S, H69K, K70R, I72IM, I85V, L89MCRF02_AG
 CU407-10CU407-10JQ585457PINA  L10I, I13V, K14R, K20I, E35DN, M36I, R41K, H69K, L89MCRF02_AG
 CU1213-09CU1213-09JQ585280PINAV32I, M46I, I47V, I54L, I84VL33F, F53L, Q58E, L89VL10I, T12E, I13AV, K14R, I15V, G16Q, K20V, E35G, M36I, P39S, R41RK, D60DN, I64V, I66F, H69K, K70E, A71V, I93IVCRF02_AG
Kim (2013)Tx07228KC120855LPV   L10I, I13V, K14KR, I15V, G16GE, L19P, K20I, M36I, N37D, R41K, K43R, Q61H, L63S, I64IL, H69K, L89M, F99LCRF02_AG
Rawizza (2013)PJ9959PJ9959KF241498LPV M46I, I54V, V82A L10I, I13V, K14R, G17E, K20I, M36I, N37S, R41K, C67H, H69K, P81PL, L89MCRF02_AG
 LN2369LN2369KF241493LPV   L10I, T12S, I13V, K14R, G17E, K20I, E35D, M36I, N37S, R41K, L63S, H69K, K70R, L89MCRF02_AG
Thiam (2013)133-HALD133-HALDJN673604PINAM46I, I47V, I54V, I84VL33I, G73SL10I, V11L, I13V, L19P, K20I, M36I, R41K, Q61H, L63V, H69K, K70R, A71V, I72T, P79A, N83S, L89TCRF02_AG
 1837HALD1837HALDJX187611LPV M46I, I54V, L76V, I84VQ58EL10I, I13V, G16E, K20I, M36I, R41K, L63HR, H69K, K70R, I72V, L89MCRF02_AG
 471-HALD471-HALDJN673637LPV M46I, I47V, I54V, V82A, I84VV11I, F53LL10I, I13V, L19P, K20I, A22V, M36I, N37S, R41K, Q61H, H69K, A71V, L89I, T91SCRF02_AG
 495-HALD495-HALDJN673647LPV M46I, I47V, I54V, I84V, L90ML33I, L89VT4S, L10I, T12M, I13A, K14M, L19P, K20I, A22V, E35D, M36I, N37D, R41RK, R57K, Q61QH, I62IV, L63P, I66F, H69K, A71VCRF02_AG
Diaz (2015)RenG15186RenG15186KT746214PINA  L10I, I13V, K14R, G16E, M36I, R41K, L63AV, H69K, K70R, L89MCRF02_AG
Abdellaziz (2016)18338MN18338MNKT339001PINAM46I, L76V, I84V L10I, T12S, I13AV, K14R, I15V, K20I, M36I, R41K, I62V, I66F, H69K, L89ICRF02_AG
 1494014940KT339037PINAM46I, I47V, L76V, I84VF53FLL10I, T12S, I13A, K14R, I15V, K20I, M36I, R41K, I62V, I66F, H69K, L89ICRF02_AG