<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation L10F
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 9
Isolates 10
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Weber (2005)01M612201M6122AY677413NFV224N88SL10FI13V, K20I, E35D, M36I, R41K, H69K, L89MCRF02_AG
Baxter (2006)48-42214221-30429DQ878456PINAM46I, I84VL10F, L33I, G73SI13V, K14R, K20I, E21ED, A22V, M36I, N37D, R41K, L63LP, H69K, K70R, A71V, L89TCRF02_AG
Charpentier (2011)CR-43CR-43FJ688249PINAM46I, V82FL10FI13V, K14R, I15V, K20I, E35D, M36I, N37D, R41K, L63T, H69K, T74TA, L89M, I93MCRF02_AG
Rawizza (2013)LN3579LN3579KF241472LPV M46I, G48M, I54V, V82SL10F, K43TI13V, K14R, K20I, E35D, M36I, R41K, C67E, H69R, T74S, L89IMCRF02_AG
 LN0319LN0319KF241469LPV M46I, I54V, V82AL10FI13V, K14R, G16E, K20I, E35D, M36I, R41K, K43R, I62V, H69K, T74E, L89MCRF02_AG
 LL5309LL5309KF241462LPV M46I, I54V, L76V, V82AL10F, Q58EI13V, I15V, G16E, K20I, E35D, M36I, R41K, L63R, I64M, H69K, K70R, L89M, T91ACRF02_AG
Thiam (2013)6667HALD6667HALDJX187625LPV M46I, L76V, I84VL10F, V11II13V, G16E, L19P, K20I, A22AV, M36I, R41K, L63R, H69K, K70R, L89I, T91ACRF02_AG
Grossman (2014)554554 LPV52M46I, I54V, V82AL10FI13V, G16Q, K20I, M36I, P39L, I62V, L63P, H69K, L89MCRF02_AG
  554KF135101LPV65M46I, I54V, V82AL10FI13V, G16Q, K20I, M36I, P39L, I62V, L63P, H69K, L89MCRF02_AG
Nerrienet (2014)U0302042U0302042JN675764LPV M46I, I54V, V82A, L90ML10F, L33I, K43T, N88DV11L, I13V, L19LV, K20V, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71V, T74S, L89T, T91ACRF02_AG