<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation I93V
Rx PI-naive
IncludeMixtures No
References 27
Patients 61
Isolates 62
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Sirivichayakul (2001)SS045098045098AF187037None   L10I, I13V, G16E, E35D, M36I, R41K, L63H, H69K, L89M, I93VCRF01_AE
Hsu (2005)BAA157667BAA157667AY870173None   L10I, I13V, E35D, M36I, R41K, K55KR, L63P, H69K, L89M, I93VCRF01_AE
Gatanaga (2007)C03-51110063-1C03-51110063-1AB640163None   L10I, I13V, G16A, E35D, M36I, R41K, L63A, H69K, L89M, I93VCRF01_AE
 C04-51110220-1C04-51110220-1AB640319None  L33FL10I, I13V, K14R, I15L, E35D, M36IV, R41K, K55R, L63P, H69K, K70R, L89M, I93VCRF01_AE
Han (2007)LN3302CNLN33EF122520None   I13V, G16E, K20R, E35D, M36I, R41K, H69K, L89M, I93VCRF01_AE
Liu (2007)fj53fj53EF432686None   L10I, I13V, E35D, M36I, R41K, K43R, L63P, H69K, V82I, L89M, I93VCRF01_AE
Bao (2008)YUN01-16YUN01-16AM886192None  L33FI13V, M36I, R41K, L63P, H69K, K70R, L89M, I93VCRF01_AE
Chang (2008)TW5112TW5112EU164906None  L33FI13V, M36I, N37S, R41K, H69K, L89M, I93VCRF01_AE
 TW3210aTW3210a None  L33FI13V, K20R, M36I, R41K, H69K, L89M, I93VCRF01_AE
Holguin (2008)SP18-348212SP18-348212EU255503None  L33FL10M, T12TA, I13V, K14KR, E35D, M36I, N37ND, R41K, I62IV, G68E, H69Q, L89M, I93VCRF01_AE
Sirivichayakul (2008)BED-15BED-15PrJQ364272None  L33FI13V, G17D, E35D, M36I, R41K, K45R, L63P, H69K, L89M, I93VCRF01_AE
 BED-28BED-28PrJQ364282None   L10I, I13V, K20R, E35D, M36I, R41K, H69K, L89M, I93VCRF01_AE
Auwanit (2009)13AE-PR13FJ463512None  L33FI13V, M36I, R41K, H69K, L89M, I93VCRF01_AE
Ayouba (2009)FD0458FD0458PIGQ352068None  L33FI13V, E35D, M36I, R41K, H69K, L89M, I93VCRF01_AE
 FD0646FD0646PIGQ352080None  L33FI13V, E35D, M36I, P39Q, R41K, H69K, L89M, I93V, L97ICRF01_AE
 FD0704FD0704PIGQ352093None   L10I, I13V, G16GE, K20KR, E35D, M36I, R41K, K45R, L63S, H69K, K70R, V82VI, L89M, I93VCRF01_AE
Fujisaki (2009)585585AB442256None  L33FL10LR, I13V, E35D, M36I, R41K, R57K, L63P, H69HKNQ, V77VIM, L89M, I93VCRF01_AE
 665665AB442323None  L33FL10I, I13V, M36I, R41K, K55KR, H69K, K70KR, V82I, L89M, I93VCRF01_AE
Ishizaki (2009)C89C89agFJ006983None   L10I, I13V, E35D, M36I, R41K, H69K, V82I, L89M, I93VCRF01_AE
Tu (2009)37PBMC37EU518279None  L33FL10V, I13V, M36V, P39Q, R41K, H69K, L89M, I93VCRF01_AE
  plasma37EU518328None  L33FL10V, I13V, M36V, P39Q, R41K, H69K, L89M, I93VCRF01_AE
Vercauteren (2009)pt326jow3TbcW88GQ400698None  L33FI13V, M36L, P39PT, R41K, H69K, L89M, I93VCRF01_AE
Hattori (2010)C06-2066297C06-2066297AB864032None  L33FL10LV, I13V, M36I, N37ND, R41K, L63P, H69K, L89M, I93VCRF01_AE
Phan (2010)ND40ND40AB519466None   L10M, I13V, G16E, E35D, M36I, R41K, D60E, Q61E, H69K, K70R, L89M, I93VCRF01_AE
 NB56NB56AB519557None  L33FI13V, M36I, R41K, E65D, H69K, L89M, I93VCRF01_AE
Zhang (2010)05178CNsd05178GQ443562None  L33FI13V, E35D, M36I, R41K, L63LP, H69K, K70KR, L89M, I93VCRF01_AE
Chen (2012)YN09DH0016YN09DH0016JQ658489None   L10I, I13V, I15V, K20I, E35D, M36I, L63P, H69K, V82I, L89M, I93VCRF01_AE
 YN09DH0056YN09DH0056JQ658525None  L33FI13V, K14N, L23LP, E35D, M36I, H69K, I72IV, L89M, I93VCRF01_AE
 YN10DH0043YN10DH0043JQ658667None   L10LI, I13V, E35D, M36I, R41K, D60DE, Q61QE, L63P, H69K, K70KR, L89M, I93VCRF01_AE
 YN10DH0044YN10DH0044JQ658668None   L10I, I13V, E35D, M36I, R41K, L63P, H69KQ, L89M, I93VCRF01_AE
 YN10DH0149YN10DH0149JQ658768None   I13V, E35D, M36I, N37S, R41K, L63P, H69KR, L89M, I93VCRF01_AE
Karlsson (2012)SE_214SE_214JQ698818None   L10I, I13V, I15V, K20KI, E35D, M36I, N37DE, K45KR, L63P, H69K, V82I, L89M, I93VCRF01_AE
Rolland (2012)AA006a03AA006a03JX446737None  L33FI13V, M36I, N37S, P39S, R41K, H69K, L89M, I93VCRF01_AE
 AA085a_wg10AA085a_wg10JX447679None   I13V, E35D, M36I, R41K, L63P, H69K, K70R, I72V, L89M, T91V, I93VCRF01_AE
Trinh (2012)VN-55VN-55HQ876698None   L10I, I13V, G16E, K20R, E35D, M36I, R41K, H69K, L89M, I93VCRF01_AE
Zeng (2012)CN1225CN1225JQ028235None  L33FI13V, M36I, R41K, H69K, L89M, I93VCRF01_AE
Frentz (2013)EHR-34005EHR-34005JX300116None   L10M, I13V, G16E, E35D, M36I, R41K, H69K, K70R, I72V, L89M, I93VCRF01_AE
Han (2013)LC216055ILC216055IJX070532None   L10IV, I13V, E35D, M36I, R41K, H69K, L89M, I93VCRF01_AE
Kiertiburanakul (2013)R12055R12055KC994203None  L33FI13V, M36I, R41K, H69K, V77VI, L89M, I93VCRF01_AE
 R74049R74049KC791269None   L10I, I13V, G16E, K20I, M36I, L63S, H69K, K70R, L89M, I93VCRF01_AE
 R71TS105R71TS105KC921583None   I13V, G16E, K20I, L33V, E35N, M36I, R41K, R57K, H69K, K70R, I72V, L89M, I93VCRF01_AE
 R74162R74162KC791381None   T12P, I13V, G16E, M36I, R41K, K43R, L63PS, G68GE, H69K, K70R, I72IT, V82I, L89M, I93VCRF01_AE
 R71127R71127KC921840None  L33FI13V, E35D, M36I, R41K, L63T, H69K, L89M, I93VCRF01_AE
 R41166R41166KC970860None   L10I, I13V, G16E, E35D, M36I, R41K, L63S, H69K, L89M, I93VCRF01_AE
 R74131R74131KC791350None  L33FI13V, A28V, M36I, N37NS, R41K, K55KR, H69K, L89M, I93VCRF01_AE
 R74002R74002KC791223None   L10LI, I13V, E35D, M36I, R41K, L63LH, H69K, V82I, L89M, I93VCRF01_AE
 X12028X12028KC994363None  L33FI13V, M36I, N37I, R41K, H69K, L89M, I93VCRF01_AE
 R74147R74147KC791366None   L10I, I13V, I15V, G16A, E35D, M36I, R41K, L63V, H69K, L89M, I93VCRF01_AE
 R71TS010R71TS010KC921493None   L10I, I13V, K20R, E35D, M36I, R41K, H69K, L89M, I93VCRF01_AE
 R12118R12118KC994258None  L33FI13V, M36I, N37T, R41K, H69K, L89M, I93VCRF01_AE
 R75020R75020KC962534None   L10IM, I13V, E35D, M36I, R41K, H69K, K70R, V82I, L89M, I93VCRF01_AE
 R71TS080R71TS080KC921559None   L10I, I13V, K14R, E35D, M36I, R41K, L63Q, I64L, H69K, L89M, I93VCRF01_AE
 R71146R71146KC921848None   L10I, E35D, M36I, R41K, L63P, H69Q, L89M, I93VCRF01_AE
 R71TS212R71TS212KC921683None  L33FI13V, K14R, K20I, M36I, R41K, K43R, H69K, L89M, I93VCRF01_AE
 R74048R74048KC791268None   L10I, I13V, G16A, E35D, M36I, R41K, D60E, H69K, L89M, I93VCRF01_AE
 R73121R73121KC810407None  L33FI13V, M36I, R41K, H69K, K70KR, L89M, I93VCRF01_AE
 R72238R72238KC857059None   L10I, I13V, G16E, E35D, M36I, R41K, L63C, H69K, L89M, I93VCRF01_AE
 R72119R72119KC856952None   I13V, I15V, E35D, M36I, R41K, L63P, H69K, L89M, I93VCRF01_AE
 R72275R72275KC857091None   L10M, I13V, E35D, M36I, R41K, R57RK, L63Q, H69K, L89M, I93VCRF01_AE
 R72155R72155KC856983None  L33FI13V, E35ED, M36I, R41K, L63LAPV, E65ED, H69K, L89M, I93VCRF01_AE
 R72255R72255KC857076None  L33FL10V, I13V, K14R, E35ED, M36I, N37NS, R41K, H69K, K70R, L89M, I93VCRF01_AE
Li (2013)20762076JQ302596None   L10LI, I13V, I15IV, K20I, M36I, N37D, R41K, L63P, H69K, V82I, L89M, I93VCRF01_AE