<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation I93L
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 79
Isolates 82
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Chantratita (2002)G65G65AF240390PINAG48V, I54M, V82AL33F, F53L, N83DL10I, G16A, K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93LCRF01_AE
Ariyoshi (2003)JPN26JPN26AY900687NFV, IDV51  L10LI, K20R, E35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
 JPN44JPN44A IDV, SQV, RTV88  K20R, E35D, M36I, N37D, L63P, H69K, L89M, I93LCRF01_AE
  JPN44BAY900691IDV, SQV, RTV, LPV204  K20R, E35D, M36I, N37D, L63P, H69K, L89M, I93LCRF01_AE
 JPN14JPN14AY900697NFV7  K20R, E35D, M36I, R41K, K45R, H69X, L89M, I93LCRF01_AE
 JPN33JPN33 NFV8  I15IV, E35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
 JPN19JPN19A NFV59N88SL10FG16E, K20IT, E35D, M36I, R41K, L63T, I64V, H69K, L89M, I93LCRF01_AE
  JPN19BAY900861NFV77N88SL10FG16E, K20I, E35D, M36I, R41K, L63T, I64V, H69K, L89M, I93LCRF01_AE
 JPN35JPN35AY900862IDV, NFV140M46I, L90M L10V, I13V, K20T, E35D, M36I, R41K, Q61H, L63P, I64V, H69K, K70R, T74S, R87X, L89M, I93LCRF01_AE
 JPN39JPN39AY900865NFV200M46I, N88SL10FI13V, K20I, E35D, M36I, R41RK, I64V, H69K, T74S, V77VI, L89M, I93LCRF01_AE
 JPN21JPN21A IDV, NFV124M46I, N88SL10F, T74TP, L89VK20I, M36I, L63LP, H69K, I85V, I93LCRF01_AE
  JPN21BAY900869IDV, NFV132M46I, N88SL10F, L89VK20I, M36I, H69K, I85V, I93LCRF01_AE
Chantratita (2005)14-000814-0008DQ130425PINA  I13V, G16E, M36I, R41K, H69K, L89M, I93LCRF01_AE
 14-001514-0015DQ130430PINA  L10I, M36I, R41K, H69K, I93LCRF01_AE
 14-002314-0023DQ130436PINA  E35D, M36I, R41K, D60E, Q61D, L63P, H69K, K70R, L89M, I93LCRF01_AE
 14-003314-0033DQ130437PINA  I13V, G16E, K20R, E35D, M36I, R41K, K43R, L63P, H69K, L89M, I93LCRF01_AE
 14-003814-0038DQ130440PINA  M36I, R41K, D60E, H69K, V82I, N88H, L89M, I93LCRF01_AE
 14-003914-0039DQ130441PINA  G16A, K20R, E35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
 14-004014-0040DQ130442PINA  K20R, E35D, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
 14-004214-0042DQ130443PINA  L10V, I15V, E35D, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
 14-005114-0051DQ130447PINA  W6R, K20R, E35D, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
 14-007114-0071DQ130457PINA  W6R, L10V, G16E, K20R, E35D, M36I, R41K, D60E, I62V, L63P, H69K, L89M, I93LCRF01_AE
 14-010714-0107DQ130476PINA  K20R, E35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
 14-012214-0122DQ130488PINAM46IN83DW6R, I13V, I15V, A22V, E35G, M36I, R41K, K55R, I62V, L63P, H69K, L89I, I93LCRF01_AE
 14-012514-0125DQ130491PINA  W6R, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
 14-012814-0128DQ130493PINA  W6R, E35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
 14-013814-0138DQ130503PINA  K20R, E35D, M36I, R41K, L63P, H69K, L89M, L90V, I93LCRF01_AE
 14-014614-0146DQ130511PINAM46I, I54V, L76V, V82FL33FW6R, L10I, E35D, M36I, R41K, K55R, Q61H, L63P, H69K, T74S, L89M, I93LCRF01_AE
 G522G522DQ130114PINAM46I, L90MQ58EL10I, I13V, I15V, K20T, E35D, M36I, R41K, I62V, L63P, H69K, A71V, T74S, V77I, V82I, L89I, I93L, L97MCRF01_AE
 G563G563DQ130136PINAD30N, M46IN88DW6R, L10V, K20R, E35D, M36I, R41K, L63P, H69K, V77I, I93LCRF01_AE
 G589G589DQ130152PINA  L10V, I13V, G16A, L19M, K20I, E35N, M36I, N37D, R41K, D60E, Q61E, L63P, H69K, L89M, I93LCRF01_AE
 G636G636DQ130181PINA  K20R, M36I, N37D, R41K, L63P, H69K, I72V, L89M, I93LCRF01_AE
 G642G642DQ130185PINA  I15V, K20R, E35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
 G688G688DQ130208PINA  E35D, M36L, R41K, K45R, Q61E, L63P, H69K, L89M, I93LCRF01_AE
 G727G727DQ130223PINA  K20R, E35D, M36I, R41K, L63T, H69K, V82I, L89M, I93LCRF01_AE
 G748G748DQ130235PINA  L10V, I13V, I15V, E35D, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
 NP132NP132DQ130247PINA  K20R, E35D, M36I, R41K, L63S, H69K, V82I, L89M, I93LCRF01_AE
 NP164NP164DQ130268PINAM46IL33I, N83DL10V, I13V, K14N, G16A, K20T, A22V, E35D, M36I, R41K, I62V, L63V, H69K, K70R, T74S, V82I, L89I, I93LCRF01_AE
 NP170NP170DQ130274PINA  L10V, G16E, K20R, E35D, M36I, R41K, H69K, I72V, L89M, I93LCRF01_AE
 NP188NP188DQ130292PINA  L10I, I13V, G16E, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
 NP214NP214DQ130301PINA  K20R, M36I, R41K, I62V, L63P, H69K, K70N, L89M, I93LCRF01_AE
 NP221NP221DQ130306PINA  K20R, E35D, M36I, N37D, R41K, D60E, H69K, L89M, I93LCRF01_AE
 NP225NP225DQ130310PINA  K20R, E35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
 NP260NP260DQ130342PINA  K20R, E35D, M36I, R41K, L63P, H69K, T74S, L89M, I93LCRF01_AE
 NP272NP272DQ130354PINA  E35D, M36I, R41K, L63P, H69K, V82I, L89M, I93LCRF01_AE
 NP290NP290DQ130370PINA  G16A, E35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
 NP292NP292DQ130372PINA  W6R, I13V, E35D, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
 NP315NP315DQ130393PINAG48V, I54V, V82A L10I, I15V, E35D, M36I, R41K, Q61E, L63P, H69K, L89I, I93LCRF01_AE
 NP321NP321DQ130399PINAN88SL10FI13V, K20I, E35D, M36I, R41K, I62V, L63P, H69K, T74A, L89M, I93LCRF01_AE
 NP330NP330DQ130407PINA  W6L, K20R, E35D, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
 VC890VC890DQ130420PINA  I13V, I15V, K20R, E34G, E35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
Hsu (2005)BAA148357BAA148357AY870143IDV, SQV, RTV65  I13V, I15V, E35D, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
 BAA154760BAA154760AY870162NFV113  K20I, E35N, M36I, N37D, R41K, L63P, H69K, T74A, L89M, I93LCRF01_AE
 BAA157679BAA157679AY870184IDV231M46MI, L90M K14R, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89M, I93LCRF01_AE
Non-B Workgroup (2005)IL276IL276 IDV81  L10I, E35D, M36I, R41K, R57K, L63T, H69R, L89M, I93LCRF01_AE
 TK1018TK1018 RTV, SQV, IDV184I84VL33F, N83DL10V, I13V, E34Q, M36I, N37S, R41K, L63P, H69K, L89M, I93LCRF01_AE
Riddler (2008)RG82111RG82111w55 LPV36  G16E, T26TS, T31TP, E35D, M36I, R41K, R57K, L63P, H69K, L89M, I93LCRF01_AE
Hamkar (2010)30Ir-HIV-DR-30GU724833PINA  T12P, K14R, K20R, E35D, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
Charpentier (2011)CR-50CR-50FJ688256PINAM46IL10FK20I, E35D, M36I, N37D, R41K, I62IV, L63T, H69K, T74A, V77VI, I85IV, L89M, I93LCRF01_AE
Jones (2012)149437149437JN669736PINA  L10I, T12P, K14R, E35D, M36I, I62V, L63P, I64V, C67D, V77I, I93LCRF01_AE
 180281180281JN670543PINAV32I, M46I, I47V, I50L, V82AK43TK20R, E35ED, M36I, L63D, I64V, I72T, I93LCRF01_AE
 180949180949JN670562PINAV32I, M46I, I47V, I50L, V82AK43TK20R, E35ED, M36I, L63D, I64V, I72T, I93LCRF01_AE
Kim (2013)Tx022KC120827LPV   I13V, K20R, E35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
Nerrienet (2014)T1005142T1005142JN675761LPV M46I, I54V, V82A, L90M L10V, G16E, K20R, E35D, M36V, P39S, R41K, K55R, I62V, L63P, H69K, A71V, I93LCRF01_AE
 U0406170U0406170JN675809LPV   E35D, M36I, R41K, L63P, H69K, V82I, L89M, I93LCRF01_AE
 U0831207U0831207JN675812LPV   K20R, E35D, M36I, R41K, L63C, G68GE, H69K, L89M, I93LCRF01_AE
 T0528149T0528149JN675798LPV  L33FI13V, R41K, K43R, L63I, I64V, H69K, K70R, L89M, I93LCRF01_AE
 T0506285T0506285JN675754LPV M46I, I47V, I54V, I84VL10F, L24IK20I, E35N, M36I, K55R, I62V, L63P, H69K, A71V, T74A, L89M, I93LCRF01_AE
 S0721226S0721226JN675785LPV   Q18E, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
 T0202184T0202184JN675789LPV   G16EK, E21EK, E35D, M36I, R41K, L63LF, H69K, R87RQ, L89M, I93LCRF01_AE
 S0610136S0610136JN675782LPV   G16E, E35D, M36I, R41K, D60E, H69K, L89M, I93LCRF01_AE
Diaz (2015)RenG16713RenG16713KT747741PINAD30DNQ58QE, N88NDL10LV, L19V, K20KR, E35D, M36MI, N37NT, R57RK, I62V, L63HN, A71AV, I72IT, V77VI, I93LCRF01_AE
 RenG13218RenG13218KT744246PINAL90M L19E, K20R, E35D, M36I, I62V, L63PT, I64V, I93LCRF01_AE
Zain (2015)MYHIVDR253MYHIVDR253KT281568PINA  I15V, M36I, H69K, L89M, I93LCRF01_AE
 MYHIVDR098MYHIVDR098KT281542PINA  I15V, G16E, M36I, R57K, H69K, V82I, L89M, I93LCRF01_AE
 MYHIVDR097MYHIVDR097KT281541PINA  G16GE, M36I, H69K, L89M, I93LCRF01_AE
 MYHIVDR125MYHIVDR125KT281522PINA  I15V, K20R, E35D, M36I, R41K, K45KR, H69K, V82VI, L89M, I93LCRF01_AE
 MYHIVDR045MYHIVDR045KT281515PINA  T12P, E35D, M36I, R57K, L63P, H69K, V82I, L89M, I93LCRF01_AE
 MYHIVDR041MYHIVDR041KT281513PINAM46I, I54IV, V82A K20R, E35D, M36I, Q61E, L63P, H69K, L89X, I93LCRF01_AE
 MYHIVDR025MYHIVDR025KT281511PINA  G16E, E35D, M36I, R41K, D60E, H69K, L89M, I93LCRF01_AE
 MYHIVDR020MYHIVDR020KT281509PINA  Q18QE, K20R, E35D, M36I, R41K, K45KR, R57RK, L63P, H69K, L89M, I93LCRF01_AE
 MYHIVDR061MYHIVDR061KT281496PINA  M36I, L63S, H69K, L89M, I93LCRF01_AE