<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L90M
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 34
Isolates 34
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Chantratita (2002)VL245VL245AF191208PINAG48V, L90ML33F, F53L, N83DL10I, I13V, E35D, M36I, R41K, K43Q, L63P, H69K, L89ICRF01_AE
 GEN15GEN15AF191199PINAM46I, L90MT74PL10V, K20R, E35D, M36I, R41K, K55R, I62V, L63P, H69K, L89MCRF01_AE
 G67G67AF240392PINAI54V, V82F, L90M L10I, I13V, K20I, E35N, M36I, R41K, L63P, H69K, T74S, L89M, I93MCRF01_AE
 G66G66AF240391PINAI54V, V82F, L90M L10I, I13V, K20I, E35N, M36I, R41K, L63P, H69K, T74S, L89M, I93MCRF01_AE
 G58G58AF240385PINAM46I, L90ML89VI13V, K20T, E35D, M36I, R41K, I62V, H69K, A71T, T74SCRF01_AE
 G51G51AF240378PINAI84V, L90ML10FI13V, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
Ariyoshi (2003)JPN42JPN42A SQV104I54V, V82F, L90ML33F, I84LL10V, I13V, I15IV, G16E, K20I, E35D, M36I, N37ND, R41K, H69K, T74S, L89I, Q92KCRF01_AE
 JPN30JPN30 NFV71L90M L10V, I13V, K20T, E35D, M36I, R41K, H69K, K70R, T74S, L89ICRF01_AE
 JPN15JPN15AY900698NFV, IDV113I54V, L90ML10F, L33II13V, K20R, E35D, M36I, R41K, I64V, H69K, L89MCRF01_AE
 JPN35JPN35AY900862IDV, NFV140M46I, L90M L10V, I13V, K20T, E35D, M36I, R41K, Q61H, L63P, I64V, H69K, K70R, T74S, R87X, L89M, I93LCRF01_AE
 JPN41JPN41A IDV, SQV, NFV125G48ST, I54V, V82F, L90M L10I, I13V, G16E, K20I, E35D, M36I, P39Q, R41K, K45V, I62V, L63P, H69K, L89MCRF01_AE
Nukoolkarn (2004)238238 LPV L90M L10I, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89MCRF01_AE
 321321 NFV L90M I13V, K20I, E35D, M36I, R41K, I64V, H69K, L89MCRF01_AE
Chantratita (2005)G522G522DQ130114PINAM46I, L90MQ58EL10I, I13V, I15V, K20T, E35D, M36I, R41K, I62V, L63P, H69K, A71V, T74S, V77I, V82I, L89I, I93L, L97MCRF01_AE
 G530G530DQ130120PINAI54V, L90M I13V, K20V, E35N, M36I, R41K, I62V, I66F, H69K, K70R, V82I, L89MCRF01_AE
 G617G617DQ130168PINAI54A, V82F, L90ML33F, L89VL10I, I13V, K20R, E35D, M36I, R41K, H69K, A71VCRF01_AE
 G639G639DQ130183PINAM46I, L90ML10F, N88GI13V, K20V, E35D, M36I, R41K, I62V, L63P, I64V, H69K, L89MCRF01_AE
 G658G658DQ130190PINAI54V, V82F, L90ML33I, L89VL10I, I13V, L19I, K20I, E35D, M36I, R41K, H69KCRF01_AE
 G720G720DQ130220PINAI84V, L90ML10FI13V, K20R, E35D, M36I, R41K, L63P, H69K, A71I, L89ICRF01_AE
 NP183NP183DQ130287PINAL90ML89VI13V, K20T, E35D, M36I, R41K, I62V, L63P, H69K, I72M, T74S, V77I, V82ICRF01_AE
 NP254NP254DQ130336PINAG48V, L90MQ58EW6R, L10I, I13V, K20R, E35D, M36I, R41K, L63P, H69K, L89ICRF01_AE
 NP316NP316DQ130394PINAL90M I13V, K20T, E35D, M36I, R41K, H69K, A71T, V82I, L89ICRF01_AE
 NP333NP333DQ130410PINAL90M K14N, G16E, K20T, E35D, M36I, P39S, R41K, I62V, H69K, K70R, A71V, V82I, L89I, I93MCRF01_AE
Hsu (2005)BAA148363BAA148363AY870148SQV, RTV35I84V, L90M L10V, I13V, K20R, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
 BAA157679BAA157679AY870184IDV231M46MI, L90M K14R, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89M, I93LCRF01_AE
 BAA161433BAA161433AY870233IDV, SQV, RTV270G48V, L90ML33F, N83DL10I, I13V, E35D, M36I, R41K, L63T, H69K, L89IMCRF01_AE
 BAA161449BAA161449AY870242SQV, RTV100G48GMRV, I54V, I84IV, L90MQ58QEL10I, I13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
Non-B Workgroup (2005)TH_215TH_215AY605617NFV N88S, L90ML10FI13V, I15V, K20T, E35D, M36I, R41K, I64V, H69K, L89MCRF01_AE
Rawizza (2013)LL0499LL0499KF241476LPV M46L, G48V, L90ML33F, N83DL10V, I13V, K20R, E35DN, M36I, N37E, P39Q, R41K, D60E, Q61E, H69K, L89IMCRF01_AE
Nerrienet (2014)T0826079T0826079JN675758LPV M46I, I47A, I84V, L90ML10F, L33I, F53LI13V, G16A, L19I, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, C67F, H69K, K70R, L89I, T91VCRF01_AE
 U0223070U0223070JN675763LPV I54V, V82A, L90ML10F, K43KT, L89VI13V, G16E, K20I, E35D, M36I, N37D, R41K, Q61H, L63R, H69K, A71T, T91SCRF01_AE
 S0916071S0916071JN675753LPV M46I, I54V, V82F, L90M L10V, K20I, E35D, M36I, R41K, Q61H, I62V, L63C, H69K, T74S, L89ICRF01_AE
 U0302042U0302042JN675764LPV M46I, I54V, V82A, L90ML10F, L33I, K43T, N88DV11L, I13V, L19LV, K20V, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71V, T74S, L89T, T91ACRF01_AE
 U0719200U0719200JN675770LPV M46I, I47A, I84V, L90ML89VL10V, I13A, K20I, M36I, K55R, L63P, H69K, A71V, I93MCRF01_AE