<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L89V
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 17
Isolates 20
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Ariyoshi (2003)JPN45JPN45A IDV64N88SL10F, L33LI, L89VI13V, K20T, E35D, M36I, R41K, I62IV, L63P, H69K, A71AT, T74TSCRF01_AE
  JPN45BAY900693IDV, APV, LPV68N88SL10F, L89VI13V, K20T, E35D, M36I, P39PS, R41K, L63P, H69K, A71TCRF01_AE
 JPN21JPN21A IDV, NFV124M46I, N88SL10F, T74TP, L89VK20I, M36I, L63LP, H69K, I85V, I93LCRF01_AE
  JPN21BAY900869IDV, NFV132M46I, N88SL10F, L89VK20I, M36I, H69K, I85V, I93LCRF01_AE
 JPN25JPN25AY900874NFV73M46I, N88SL10F, L33I, Q58QE, L89VI13V, K20T, E35D, M36I, R41K, I62IV, H69KCRF01_AE
Nukoolkarn (2004)220220 RTV, IDV I54V, V82AG48I, F53L, L89VL10I, I13V, K20I, E35D, M36I, N37D, R41K, L63P, H69K, A71VCRF01_AE
Hsu (2005)BAA150607BAA150607AY870152SQV, RTV78M46ML, G48V, I84IV, L90LML89VI13V, E35D, M36I, R41K, H69KCRF01_AE
 BAA161439BAA161439AY870235NFV252I84IVL10F, L89VI13V, K20T, E35D, M36I, R41K, H69K, A71T, T74SCRF01_AE
Non-B Workgroup (2005)TK3028TK3028 SQV, NFV115 L89VI13V, E35D, M36I, R41K, H69K, A71ATCRF01_AE
  TK3028a SQV, NFV186 L89VI13V, K20T, E35D, M36I, N37NY, R41K, H69K, A71TCRF01_AE
Tee (2006)MYKL182204MYKL1822AY960956RTV, IDV M46I, I84VL89VL10I, I13A, K14R, K20I, E35D, M36I, R41K, K55R, I66F, H69K, A71TCRF01_AE
Nerrienet (2014)R0712188R0712188JN675747LPV M46I, G48V, I54V, L76V, V82TL89VL10R, I13A, K14R, K20I, E35D, M36I, N37D, R41K, K55N, D60E, L63P, H69K, K70R, A71V, T91A, Q92KCRF01_AE
 Q0920081Q0920081JN675744LPV M46I, I54V, V82SL24I, L33I, Q58E, L89VL10I, I13V, K20KR, E35D, M36I, N37DE, K55KR, R57K, I62V, L63P, H69K, T74SCRF01_AE
 T1022129T1022129JN675762LPV M46L, I54V, I84VL10F, V11I, L33I, Q58E, N83D, L89VT4P, I13V, K14R, K20R, A22V, E35S, M36I, R41K, D60E, I62V, L63P, H69K, A71V, T91G, Q92ECRF01_AE
 U0316214U0316214JN675765LPV G48V, I54V, V82AL89VT4S, L10I, V11L, I13V, K20I, E35D, M36I, I62IV, L63P, H69K, A71TCRF01_AE
 U0407179U0407179JN675767LPV M46I, I84V, L90ML10F, L33F, F53L, Q58E, G73GS, N88G, L89VI13V, K20T, E35D, M36I, R41K, K55R, R57K, L63P, I66IF, H69K, A71VCRF01_AE
 U0223070U0223070JN675763LPV I54V, V82A, L90ML10F, K43KT, L89VI13V, G16E, K20I, E35D, M36I, N37D, R41K, Q61H, L63R, H69K, A71T, T91SCRF01_AE
 U0527075U0527075JN675769LPV M46I, I47V, L76V, I84VL33I, F53L, Q58E, L89VL10V, I13A, G16E, K20I, E35D, M36I, N37H, P39S, R41K, K55R, D60E, Q61H, I62V, I66F, H69K, K70R, A71VCRF01_AE
 S0822156S0822156JN675752LPV M46L, I47V, G48V, I54V, V82T, I84VF53L, L89VL10I, I13A, K20I, M36I, R41K, L63P, I66F, H69K, A71VCRF01_AE
 U0719200U0719200JN675770LPV M46I, I47A, I84V, L90ML89VL10V, I13A, K20I, M36I, K55R, L63P, H69K, A71V, I93MCRF01_AE