<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L89I
Rx PI-naive
IncludeMixtures No
References 29
Patients 46
Isolates 50
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Lan (2003)NTHvr180NTHvr180AY238215None   I13V, G16E, E35D, M36I, R41K, H69K, L89ICRF01_AE
 NTHvr72NTHvr72AY238312None   L10I, I13V, G16GE, M36I, R41K, L63C, H69K, K70KR, L89ICRF01_AE
Tovanabutra (2003)02TH_OUR133202_1332AF529573None   I13V, I15V, E35D, M36I, R41K, R57K, H69K, I72V, L89ICRF01_AE
Montes (2004)MB_patRAI01_RAI715AJ577978None   L10V, I13V, G16E, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
Hsu (2005)LYH_AY870218BAA161407AY870218None  L33FI13V, G16E, E35D, M36I, R41K, L63S, H69K, K70R, L89I, I93LCRF01_AE
 BAA150613BAA150613AY870154None   I13V, G16E, E35D, M36I, R41K, H69K, V82I, L89ICRF01_AE
 BAA157677BAA157677AY870182None   I13V, I15V, E35D, M36I, R41K, R57K, H69K, V77I, L89I, T91VCRF01_AE
 BAA157681BAA157681AY870186None   L10I, I13IV, G16GE, K20M, E35D, M36I, R41K, H69K, L89ICRF01_AE
Ly (2005)NL_KHM_CA35KHM_CA35DQ013542None   I13V, E35D, M36I, R41K, H69K, L89ICRF01_AE
 NL_KHM_POP5KHM_POP5DQ013605None   T12P, I13V, G16GE, E35D, M36I, R41K, L63H, H69K, K70Q, L89ICRF01_AE
Derache (2007)12661266EF064505None   I13V, K14R, K20I, M36I, R41K, L63P, C67H, H69K, L89ICRF01_AE
Gatanaga (2007)C03-51110041-1C03-51110041-1AB640141None   K20R, E35D, M36I, R41K, H69K, K70R, L89I, T91ACRF01_AE
Liu (2007)fj07fj07EF432662None  V11II13V, G16E, K20I, M36I, R41K, I64V, H69K, L89I, Q92RCRF01_AE
 fj10fj10EF432719None   L10V, I13V, M36I, R41K, H69K, L89ICRF01_AE
Chang (2008)TW11250TW11250EU164923None   I13V, E35D, M36I, R41K, Q58QR, L63S, H69K, K70R, L89ICRF01_AE
 TW10012aTW10012a None   I13V, E35D, M36I, R41K, L63S, H69K, K70R, L89ICRF01_AE
Ibe (2008)333333AB356330None   L10I, I13V, E35D, M36I, R41K, H69K, K70R, V82VI, L89I, L97LICRF01_AE
Sirivichayakul (2008)NBC-18NBC-18PrJQ364318None   K20R, M36I, R41K, L63P, H69K, I72E, L89I, I93HCRF01_AE
 NBC-37NBC-37PrJQ364337None   L10I, I13V, G16E, E35D, M36I, N37D, R41K, H69K, K70R, I72V, P79H, L89ICRF01_AE
Auwanit (2009)42AE-PR42FJ463518None   K14R, I15IV, L19LQ, E35D, M36I, R41K, I62V, L63ST, H69K, K70R, V82I, L89ICRF01_AE
Ayouba (2009)FD0435FD0435PIGQ352108None   I13V, K14KR, E35D, M36I, R41K, H69K, L89ICRF01_AE
Ishizaki (2009)A2_424A2_424FJ007095None   L10I, I13V, M36I, R41K, H69K, L89ICRF01_AE
 A70A70FJ007137None   I13V, G16E, E35D, M36I, R41K, R57K, H69K, L89I, Q92KCRF01_AE
Vercauteren (2009)pt18532146907658GQ399171None   I13V, M36I, R41K, H69K, L89ICRF01_AE
 pt133sUWqTcMx34GQ400891None   E35D, M36I, R41K, R57K, H69K, V82I, L89ICRF01_AE
Jullaksorn (2010)CR17CR17-Apr08RGQ857295None   I13V, M36I, R41K, K43R, L63P, H69K, K70R, L89ICRF01_AE
  CR17-Jul08RGQ857328None   I13V, M36I, R41K, K43R, L63P, H69K, K70R, L89ICRF01_AE
  CR17-Oct08DGQ857359None   I13V, M36I, R41K, K43R, L63P, H69K, K70R, I72V, V82I, L89ICRF01_AE
  CR17-Jan09DGQ857392None   I13V, M36I, R41K, K43R, H69K, K70R, V82I, L89ICRF01_AE
  CR17-Apr09DGQ857423None   Q7H, I13V, M36I, R41K, K43R, H69K, K70R, V82I, L89ICRF01_AE
Phan (2010)O942O942AB519512None   I13V, G16E, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
 NB27NB27AB519539None   T12P, G16E, E35D, M36I, N37D, R41K, L63C, H69K, K70R, L89ICRF01_AE
 AH18AH18AB519570None   L10I, I13V, M36I, L38X, R41K, H69K, L89ICRF01_AE
 ND09ND09AB519597None   L10V, I13V, G16E, K20R, E35D, M36I, R41K, H69K, I72T, L89ICRF01_AE
 ND34ND34AB519603None   L10I, I13V, G16E, M36I, R41K, H69K, L89ICRF01_AE
Bontell (2011)Pat04508.VL772HsHQ852871None   L10I, I13V, G16E, L19LI, E35D, M36I, R41K, L63T, H69K, L89ICRF01_AE
Dean (2011)IVVI7283IVVI7283JQ312415None   I13V, G16A, E35D, M36I, N37D, R41K, R57K, G68GE, H69K, K70R, L89ICRF01_AE
 IVVI7392IVVI7392JQ312420None   I13V, G16A, E35D, M36I, N37D, R41K, R57K, G68GE, H69K, K70R, L89ICRF01_AE
Hamers (2011)CP076301920CP076301920HQ995392None   I13V, E35D, M36I, R41K, R57K, L63P, I64M, H69K, L89ICRF01_AE
Lazaro (2011)AG-M12AG-M12HQ542622None   L10I, I13V, M36I, R41K, H69K, V82I, L89ICRF01_AE
Ngo-Giang-Huong (2011)PHPT2972PHPT2972PR-RTHQ996523None   L10I, T12A, I13V, E35D, M36I, R41K, R57K, H69K, L89ICRF01_AE
Su (2011)LZ2034LZ2034HQ588196None   I13V, E35D, M36I, R41K, H69K, L89ICRF01_AE
De Gascun (2012)IRL39742IRL39742JN622230None   I13V, G16E, E35D, M36I, R41K, H69K, L89I, Q92RCRF01_AE
Karlsson (2012)SE_155SE_155JQ698774None   E35D, M36I, R41K, R57K, H69K, V82I, L89ICRF01_AE
Rolland (2012)AA063a_WG35AA063a_WG35JX447408None   I13V, E35D, M36I, R41K, K45R, R57K, H69K, L89ICRF01_AE
Telan (2012)1111785211117852AB747500None   K20R, M36I, R41K, L63P, H69K, L89I, I93LCRF01_AE
Tran (2012)HPA409HPA409AB690942None   L10LI, I13V, G16E, E35D, M36I, R41K, L63T, H69K, L89ICRF01_AE
Frentz (2013)EHR-02073EHR-02073JX299579None   I13V, G16E, K20R, E35D, M36I, R41K, R57K, H69K, L89I, Q92KCRF01_AE
 EHR-06236EHR-06236JX299643None   I13V, G16E, K20R, E35D, M36I, R41K, R57K, H69K, L89I, Q92KCRF01_AE
 EHR-501156EHR-501156JX300371None   I13V, G16E, E35D, M36I, R41K, H69K, K70R, L89I, I93LCRF01_AE

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