<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L89I
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 19
Isolates 20
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Ariyoshi (2003)JPN42JPN42A SQV104I54V, V82F, L90ML33F, I84LL10V, I13V, I15IV, G16E, K20I, E35D, M36I, N37ND, R41K, H69K, T74S, L89I, Q92KCRF01_AE
 JPN30JPN30 NFV71L90M L10V, I13V, K20T, E35D, M36I, R41K, H69K, K70R, T74S, L89ICRF01_AE
Hsu (2005)BAA150624BAA150624AY870158SQV, RTV31G48V, I84VL33F, Q58E, N83DL10V, I13V, K14KN, K20R, E35D, M36I, R41K, L63LP, H69K, L89ICRF01_AE
 BAA161430BAA161430AY870232IDV, SQV88G48V, I54V, V82AF53LL10I, I13V, L19LV, K20R, E35D, M36I, N37D, R41K, I62V, L63LP, H69K, A71T, T74S, L89ICRF01_AE
Non-B Workgroup (2005)TK5004TK5004 SQV, IDV, NFV, RTV, LPV145G48V, I54A, V82A L10I, V11VL, I13V, K14R, I15IV, K20I, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
Baxter (2006)48-14261426-30225DQ877815PINAG48V, I54A, V82A T4TS, L10I, V11L, I13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
 48-41134113-30319DQ878344PINAI54V, V82A L10I, I13V, G16E, L19I, K20I, E35D, M36I, P39S, R41K, D60DE, I62V, H69K, K70R, A71IV, I72V, T74A, L89ICRF01_AE
von Wyl (2007)345869337EF449787PINAI54VN83DL10I, I13V, G16A, A22V, E35D, M36I, R41K, L63V, H69K, L89ICRF01_AE
Rosen-Zvi (2008)1606p16-2 SQV, RTV, IDV, LPV287V82F L10I, T12A, I13V, E35D, M36I, R41K, R57K, H69K, L89ICRF01_AE
Charpentier (2011)4CP 001-045 Unknown, IDVNAL90ML33IL10V, I13V, L19F, K20T, E35D, M36I, R41K, R57K, L63P, H69K, T74S, L89ICRF01_AE
Ferradini (2011)50789PRHM026303APV, LPV24M46I, L76V, I84VL10FI13V, G16E, E21K, E35D, M36I, R41K, H69K, I72R, L89ICRF01_AE
Nerrienet (2014)S0815116S0815116JN675751LPV V32I, I47AL10FI13V, M36I, R41K, H69K, L89ICRF01_AE
 55JN675803LPV   W6R, Q18R, K20R, E35D, M36I, R41K, H69K, K70R, I72E, V77E, T80A, L89I, L90W, T91PCRF01_AE
 R0917161R0917161JN675781LPV   L10I, I13V, G16E, M36I, R41K, H69K, L89ICRF01_AE
 T0826079T0826079JN675758LPV M46I, I47A, I84V, L90ML10F, L33I, F53LI13V, G16A, L19I, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, C67F, H69K, K70R, L89I, T91VCRF01_AE
 R0130090R0130090JN675745LPV M46I, L76V, I84VL10FI13V, G16E, E21K, E35D, M36I, R41K, H69K, I72R, L89ICRF01_AE
 S0916071S0916071JN675753LPV M46I, I54V, V82F, L90M L10V, K20I, E35D, M36I, R41K, Q61H, I62V, L63C, H69K, T74S, L89ICRF01_AE
 R0606212R0606212JN675746LPV I54V, V82AL10F, N83DI13V, K20R, A22V, M36I, N37D, R41K, L63LP, H69K, L89I, T91ACRF01_AE
 U0907156U0907156JN675771LPV V32I, M46I, I47V, I54M, L90ML33F, Q58E, N83DL10V, I13V, G16A, M36I, N37D, R41K, K55R, D60N, L63P, I64V, H69K, K70R, A71IV, G73GD, L89ICRF01_AE
 T0518207T0518207JN675755LPV M46MI, I54V, V82AL10F, L33LI, Q58EI13V, E35D, M36I, H69K, K70R, L89ICRF01_AE