<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation I84V
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 16
Isolates 16
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Montes (2004)MB_patCAL00_CAL703AJ577857SQV, IDV, RTV98I84V I13V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89TCRF01_AE
Hsu (2005)BAA148363BAA148363AY870148SQV, RTV35I84V, L90M L10V, I13V, K20R, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
 BAA150624BAA150624AY870158SQV, RTV31G48V, I84VL33F, Q58E, N83DL10V, I13V, K14KN, K20R, E35D, M36I, R41K, L63LP, H69K, L89ICRF01_AE
Non-B Workgroup (2005)TK1018TK1018 RTV, SQV, IDV184I84VL33F, N83DL10V, I13V, E34Q, M36I, N37S, R41K, L63P, H69K, L89M, I93LCRF01_AE
Tee (2006)MYKL182204MYKL1822AY960956RTV, IDV M46I, I84VL89VL10I, I13A, K14R, K20I, E35D, M36I, R41K, K55R, I66F, H69K, A71TCRF01_AE
Ferradini (2011)50789PRHM026303APV, LPV24M46I, L76V, I84VL10FI13V, G16E, E21K, E35D, M36I, R41K, H69K, I72R, L89ICRF01_AE
Nerrienet (2014)T0826079T0826079JN675758LPV M46I, I47A, I84V, L90ML10F, L33I, F53LI13V, G16A, L19I, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, C67F, H69K, K70R, L89I, T91VCRF01_AE
 T1022129T1022129JN675762LPV M46L, I54V, I84VL10F, V11I, L33I, Q58E, N83D, L89VT4P, I13V, K14R, K20R, A22V, E35S, M36I, R41K, D60E, I62V, L63P, H69K, A71V, T91G, Q92ECRF01_AE
 U0407179U0407179JN675767LPV M46I, I84V, L90ML10F, L33F, F53L, Q58E, G73GS, N88G, L89VI13V, K20T, E35D, M36I, R41K, K55R, R57K, L63P, I66IF, H69K, A71VCRF01_AE
 R1113090R1113090JN675748LPV M46I, I47V, L76V, I84VL10FI13V, G16Q, L19V, K20I, E35D, M36I, P39S, R41K, K55R, D60E, I66F, H69K, A71AV, L89MCRF01_AE
 S0428149S0428149JN675749LPV M46I, L76V, I84VF53LL10I, I13V, I15V, K20I, E35D, M36I, R41K, K55R, D60E, L63P, I66F, H69K, K70R, L89MCRF01_AE
 R0130090R0130090JN675745LPV M46I, L76V, I84VL10FI13V, G16E, E21K, E35D, M36I, R41K, H69K, I72R, L89ICRF01_AE
 T0506285T0506285JN675754LPV M46I, I47V, I54V, I84VL10F, L24IK20I, E35N, M36I, K55R, I62V, L63P, H69K, A71V, T74A, L89M, I93LCRF01_AE
 U0527075U0527075JN675769LPV M46I, I47V, L76V, I84VL33I, F53L, Q58E, L89VL10V, I13A, G16E, K20I, E35D, M36I, N37H, P39S, R41K, K55R, D60E, Q61H, I62V, I66F, H69K, K70R, A71VCRF01_AE
 S0822156S0822156JN675752LPV M46L, I47V, G48V, I54V, V82T, I84VF53L, L89VL10I, I13A, K20I, M36I, R41K, L63P, I66F, H69K, A71VCRF01_AE
 U0719200U0719200JN675770LPV M46I, I47A, I84V, L90ML89VL10V, I13A, K20I, M36I, K55R, L63P, H69K, A71V, I93MCRF01_AE