<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation N83D
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 29
Isolates 29
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Chantratita (2002)VL245VL245AF191208PINAG48V, L90ML33F, F53L, N83DL10I, I13V, E35D, M36I, R41K, K43Q, L63P, H69K, L89ICRF01_AE
 GEN19GEN19AF191202PINAG48VL33F, F53L, N83DL10V, I13V, G16E, K20R, E35D, M36I, P39S, R41K, H69K, K70R, T74S, L89MCRF01_AE
 G73G73AF240396PINAM46L, I84VL33I, N83DL10V, I13V, A22V, E35D, M36I, R41K, H69K, T74S, L89ICRF01_AE
 G65G65AF240390PINAG48V, I54M, V82AL33F, F53L, N83DL10I, G16A, K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93LCRF01_AE
 G59G59AF240386PINAI84VL33I, N83DL10Y, I13V, E35D, M36I, R41K, F53I, L63P, H69K, L89ICRF01_AE
Ariyoshi (2003)JPN31JPN31AY900699SQV, NFV132 L33LI, N83D, L89IVL10LI, I13V, K20KT, A22AV, E35D, M36I, R41K, I62V, H69KCRF01_AE
Nukoolkarn (2004)7474 RTV I54V, V82AL33F, N83DL10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89MCRF01_AE
Chantratita (2005)14-010314-0103DQ130473PINA L33F, I54C, N83DI13V, G16A, K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74A, L89MCRF01_AE
 14-011514-0115DQ130483PINAV82AL33F, K43T, N83DL10I, I13V, E35D, M36I, R41K, I62V, H69K, L89MCRF01_AE
 14-012214-0122DQ130488PINAM46IN83DW6R, I13V, I15V, A22V, E35G, M36I, R41K, K55R, I62V, L63P, H69K, L89I, I93LCRF01_AE
 14-013514-0135DQ130500PINAM46LL33I, N83DP9A, L10R, I13V, K20R, A22V, M36I, N37D, R41K, I62V, I64V, H69K, K70R, L89MCRF01_AE
 G513G513DQ130109PINAM46LN83DI13V, A22V, E35D, M36I, R41K, R57K, H69K, L89ICRF01_AE
 G558G558DQ130132PINAI54V, V82AL33F, N83DL10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89MCRF01_AE
 G602G602DQ130159PINAI54V, I84VN83DL10I, I13V, A22V, L33M, E35D, M36I, R41K, I62V, H69K, T74A, L89ICRF01_AE
 G605G605DQ130161PINAI54V, V82AL33F, Q58E, N83DL10V, I13V, E35D, M36I, R41K, H69K, L89ICRF01_AE
 G713G713DQ130219PINAV82AL33F, N83DL10V, I13V, I15V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 NP164NP164DQ130268PINAM46IL33I, N83DL10V, I13V, K14N, G16A, K20T, A22V, E35D, M36I, R41K, I62V, L63V, H69K, K70R, T74S, V82I, L89I, I93LCRF01_AE
 NP293NP293DQ130373PINAG48M, I54V, V82AF53L, N83DL10V, I13V, G16E, K20R, A22V, E35D, M36I, P39S, R41K, I62V, L63H, H69K, I72V, L89I, T91SCRF01_AE
 NP324NP324DQ130402PINAG48V, I50V, I54S, V82AL33F, F53L, N83DL10I, I13V, K20R, E34V, E35D, M36I, I62V, I66F, H69K, T74A, L89MCRF01_AE
Hsu (2005)BAA150624BAA150624AY870158SQV, RTV31G48V, I84VL33F, Q58E, N83DL10V, I13V, K14KN, K20R, E35D, M36I, R41K, L63LP, H69K, L89ICRF01_AE
 BAA150627BAA150627AY870159SQV, RTV61G48V, I54IV, V82AL33F, F53L, N83DL10I, I13V, M36L, R41K, I62IV, L63P, H69K, T74S, L89IM, I93IVCRF01_AE
 BAA157678BAA157678AY870183SQV, RTV131G48VL33F, N83DI13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BAA161433BAA161433AY870233IDV, SQV, RTV270G48V, L90ML33F, N83DL10I, I13V, E35D, M36I, R41K, L63T, H69K, L89IMCRF01_AE
Non-B Workgroup (2005)TK1018TK1018 RTV, SQV, IDV184I84VL33F, N83DL10V, I13V, E34Q, M36I, N37S, R41K, L63P, H69K, L89M, I93LCRF01_AE
von Wyl (2007)345869337EF449787PINAI54VN83DL10I, I13V, G16A, A22V, E35D, M36I, R41K, L63V, H69K, L89ICRF01_AE
 70496347EF449835PINA N83DI13V, M36L, N37T, R41K, H69K, L89ICRF01_AE
Rawizza (2013)LL0499LL0499KF241476LPV M46L, G48V, L90ML33F, N83DL10V, I13V, K20R, E35DN, M36I, N37E, P39Q, R41K, D60E, Q61E, H69K, L89IMCRF01_AE
Nerrienet (2014)T1022129T1022129JN675762LPV M46L, I54V, I84VL10F, V11I, L33I, Q58E, N83D, L89VT4P, I13V, K14R, K20R, A22V, E35S, M36I, R41K, D60E, I62V, L63P, H69K, A71V, T91G, Q92ECRF01_AE
 R0606212R0606212JN675746LPV I54V, V82AL10F, N83DI13V, K20R, A22V, M36I, N37D, R41K, L63LP, H69K, L89I, T91ACRF01_AE