<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation T74S
Rx PI-naive
IncludeMixtures No
References 25
Patients 47
Isolates 47
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Tovanabutra (2003)02TH_OUR133102_1331AF529572None  L33II13V, E35D, M36I, R41K, K43R, H69K, T74S, L89MCRF01_AE
Ly (2005)NL_KHM_CD15KHM_CD15DQ013645None   E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Tee (2006)MYKL147703MYKL1477AY960938None   I13V, E35N, M36I, R41K, Y59D, H69K, I72V, T74S, L89M, I93LCRF01_AE
Watanaveeradej (2006)00TH_C225700_C2257AY945717None   I13V, E35D, M36I, R41K, I62V, I64V, H69K, T74S, L89MCRF01_AE
Gatanaga (2007)C03-5555-5546-1C03-5555-5546-1AB640386None   I13V, K20I, E35D, M36I, R41K, R57K, H69K, K70R, T74S, L89MCRF01_AE
Liu (2007)fj45fj45EF432678None   E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 fj74fj74EF432698None   I13V, M36I, R41K, L63P, H69K, K70R, T74S, L89M, I93LCRF01_AE
Chang (2008)TW0301aTW0301a None   I13V, K20I, E35D, M36I, R41K, I62V, H69K, K70R, T74S, V77VI, L89MCRF01_AE
Ibe (2008)164164AB356211None   E35D, M36I, R41K, L63P, H69K, I72V, T74S, V77I, L89M, I93LCRF01_AE
 437437AB356406None   V11A, I13V, K20I, E35D, M36I, R41K, L63LI, H69K, K70R, T74S, L89M, T91ACRF01_AE
Nguyen (2008)001VN001 None   I13V, E35D, M36I, R41K, H69K, T74S, L89M, I93L, F99XCRF01_AE
Ishizaki (2009)C25C25FJ006967None   I13V, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 A388A388ctFJ007305None   I13V, M36I, R41K, L63P, H69K, T74S, L89M, I93LCRF01_AE
Hattori (2010)C06-51110447C06-51110447AB864854None   L10V, G16E, E35D, M36I, R41K, I62M, H69K, T74S, L89MCRF01_AE
 C05-206802C05-206802AB864589None   T12P, I13V, E35D, M36I, R41K, I62V, H69K, T74S, L89MCRF01_AE
Phan (2010)AH42AH42AB519589None   I15V, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Zhang (2010)0518CNsd0518GQ443554None   E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Bontell (2011)Pat04908.VL767HsHQ852867None   G16E, K20KI, E35D, M36I, P39PS, R41K, I62IV, L63C, H69K, T74S, L89MCRF01_AE
 Pat00309.VL985UiHQ852913None   I15V, G16E, E35D, M36I, R41K, L63C, H69K, T74S, L89M, I93LCRF01_AE
Ng (2011)HM140HM140HQ539165None   T12P, I13V, K14R, E35D, M36I, R41K, L63S, H69K, T74S, L89MCRF01_AE
Su (2011)LZ2055LZ2055HQ588197None   I13V, M36I, R41K, H69K, K70R, T74S, L89M, I93L, G94ACRF01_AE
Zeng (2011)G1G1JF505568None   I13V, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Nazziwa (2012)51376305137630JX499010None   I13V, K20I, E35D, M36I, N37S, R41K, R57K, H69K, T74S, L89MCRF01_AE
Yang (2012)GZ158GZ158JN848878None   I13V, E35ED, M36I, R41K, L63C, H69K, T74S, L89M, I93LCRF01_AE
 GZ235GZ235JN848909None   G16E, L19I, E35D, M36I, R41K, R57RK, H69K, K70KR, T74S, L89MCRF01_AE
 GZ244GZ244JN848912None   G16E, L19I, E35D, M36I, R41K, R57RK, H69K, K70KR, T74S, L89MCRF01_AE
Zeng (2012)CN0668CN0668JQ028207None   I13V, G16E, E35D, M36I, P39S, R41K, I62V, H69K, K70R, T74S, L89MCRF01_AE
Avidor (2013)17711771KC184230None   I13V, I15V, E35D, M36I, R41K, I62V, H69K, T74S, L89MCRF01_AE
Kiertiburanakul (2013)R73192R73192KC810468None   I13V, E35D, M36I, N37D, L63P, H69K, K70KR, T74S, L89M, I93LCRF01_AE
 R71TS109R71TS109KC921587None   I13V, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93LCRF01_AE
 R41163R41163KC970899None   H69K, T74S, V77I, L89M, I93LCRF01_AE
 R73235R73235KC810509None  G48GEI13V, K20R, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93LCRF01_AE
 X12TS034X12TS034KC994430None   L10IV, T12P, I13V, L19M, E35D, M36I, R41K, R57K, H69K, T74S, L89MCRF01_AE
 X12TS026X12TS026KC994422None   L10V, T12P, I13V, L19M, E35D, M36I, R41K, H69K, T74S, L89MCRF01_AE
 R71TS169R71TS169KC921645None   I13V, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93LCRF01_AE
 R41047R41047KC970933None   I13V, M36I, I62V, L63Q, I64M, H69K, K70M, T74S, L89MCRF01_AE
 R74082R74082KC791301None   I13V, E35D, M36I, N37D, I62V, L63P, H69K, K70R, T74S, L89MCRF01_AE
 R71205R71205KC921440None   I13V, E35D, M36I, R41K, R57K, H69K, T74S, L89M, I93LCRF01_AE
 R12130R12130KC994268None   L10V, T12P, I13V, L19IM, E35D, M36I, R41K, R57K, H69K, T74S, L89MCRF01_AE
 R74183R74183KC791402None   L10V, I13V, G16E, K20R, E35D, M36I, P39PS, R41K, R57K, I62V, L63H, H69K, K70R, I72V, T74S, L89MCRF01_AE
 R74105R74105KC791324None   L10LV, G16GA, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 R71TS130R71TS130KC921607None   I13V, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 R75021R75021KC962538None   E35D, M36I, R41K, Q61E, I62IV, L63P, H69K, T74S, L89M, I93LCRF01_AE
 R73020R73020KC810556None   G17E, K20R, M36I, R41K, I62V, H69K, T74S, L89M, I93LCRF01_AE
Telan (2013)1112847611128476AB747503None   T12P, I13V, E35D, M36I, R41K, L63C, H69K, T74S, V77I, L89MCRF01_AE
Van Zyl (2013)13671068KC422854None  Q58ET12S, I13V, I15V, L19I, E35D, M36I, R41K, R57RK, Q61E, L63P, H69K, I72IV, T74S, V82VI, L89M, I93LCRF01_AE
Lee (2014)AMU080AMU080KJ906696None   T12TA, I13V, I15IV, G16GE, L19LI, E35D, M36I, R41K, R57K, L63IMV, H69K, K70KR, I72IV, T74S, L89MCRF01_AE