<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation T74S
Rx PI-naive
IncludeMixtures No
References 50
Patients 105
Isolates 105
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Tovanabutra (2003)02TH_OUR133102_1331AF529572None  L33II13V, E35D, M36I, R41K, K43R, H69K, T74S, L89MCRF01_AE
Ly (2005)NL_KHM_CD15KHM_CD15DQ013645None   E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Tee (2005)03MYKLZai03_ZaiAY904539None   I13V, E35D, H69K, T74S, L89MCRF01_AE
Tee (2006)MYKL147703MYKL1477AY960938None   I13V, E35N, M36I, R41K, Y59D, H69K, I72V, T74S, L89M, I93LCRF01_AE
Watanaveeradej (2006)00TH_C225700_C2257AY945717None   I13V, E35D, M36I, R41K, I62V, I64V, H69K, T74S, L89MCRF01_AE
Gatanaga (2007)C03-5555-5546-1C03-5555-5546-1AB640386None   I13V, K20I, E35D, M36I, R41K, R57K, H69K, K70R, T74S, L89MCRF01_AE
Liu (2007)fj45fj45EF432678None   E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 fj74fj74EF432698None   I13V, M36I, R41K, L63P, H69K, K70R, T74S, L89M, I93LCRF01_AE
Chang (2008)TW0301aTW0301a None   I13V, K20I, E35D, M36I, R41K, I62V, H69K, K70R, T74S, V77VI, L89MCRF01_AE
Ibe (2008)164164AB356211None   E35D, M36I, R41K, L63P, H69K, I72V, T74S, V77I, L89M, I93LCRF01_AE
 437437AB356406None   V11A, I13V, K20I, E35D, M36I, R41K, L63LI, H69K, K70R, T74S, L89M, T91ACRF01_AE
Nguyen (2008)001VN001 None   I13V, E35D, M36I, R41K, H69K, T74S, L89M, I93L, F99XCRF01_AE
Ishizaki (2009)C25C25FJ006967None   I13V, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 A388A388ctFJ007305None   I13V, M36I, R41K, L63P, H69K, T74S, L89M, I93LCRF01_AE
Hattori (2010)C06-51110447C06-51110447AB864854None   L10V, G16E, E35D, M36I, R41K, I62M, H69K, T74S, L89MCRF01_AE
 C05-206802C05-206802AB864589None   T12P, I13V, E35D, M36I, R41K, I62V, H69K, T74S, L89MCRF01_AE
Phan (2010)AH42AH42AB519589None   I15V, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Zhang (2010)0518CNsd0518GQ443554None   E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Bontell (2011)Pat04908.VL767HsHQ852867None   G16E, K20KI, E35D, M36I, P39PS, R41K, I62IV, L63C, H69K, T74S, L89MCRF01_AE
 Pat00309.VL985UiHQ852913None   I15V, G16E, E35D, M36I, R41K, L63C, H69K, T74S, L89M, I93LCRF01_AE
Ng (2011)HM140HM140HQ539165None   T12P, I13V, K14R, E35D, M36I, R41K, L63S, H69K, T74S, L89MCRF01_AE
Su (2011)LZ2055LZ2055HQ588197None   I13V, M36I, R41K, H69K, K70R, T74S, L89M, I93L, G94ACRF01_AE
Zeng (2011)G1G1JF505568None   I13V, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
De Gascun (2012)IRL14463IRL14463JN622290None   I13V, K20KR, E35D, M36I, R41K, R57RK, I62V, L63T, H69K, T74S, R87RI, L89MCRF01_AE
Thao (2012)HCMC_384HCMC_384JN786583None   E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Yang (2012)GZ158GZ158JN848878None   I13V, E35ED, M36I, R41K, L63C, H69K, T74S, L89M, I93LCRF01_AE
 GZ235GZ235JN848909None   G16E, L19I, E35D, M36I, R41K, R57RK, H69K, K70KR, T74S, L89MCRF01_AE
 GZ244GZ244JN848912None   G16E, L19I, E35D, M36I, R41K, R57RK, H69K, K70KR, T74S, L89MCRF01_AE
Zeng (2012)CN0668CN0668JQ028207None   I13V, G16E, E35D, M36I, P39S, R41K, I62V, H69K, K70R, T74S, L89MCRF01_AE
Avidor (2013)17711771KC184230None   I13V, I15V, E35D, M36I, R41K, I62V, H69K, T74S, L89MCRF01_AE
Chow (2013)MY1MN781MY1MN781KC478038None   I15V, E35D, M36I, H69K, T74S, L89M, I93LCRF01_AE
Han (2013)10LN30047410LN300474KC888232None   I13V, I15V, L19I, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 11LN30083211LN300832KC888398None   I13V, I15V, L19M, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 10LN30050110LN300501KC888242None   I15IV, L19V, E35D, M36I, R41K, H69K, K70R, T74S, V77I, L89M, I93LCRF01_AE
 09LN30042209LN300422KC888211None   I13V, I15V, L19M, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 10LN32096710LN320967KC888314None   I13V, I15V, L19M, E35D, M36I, R41K, H69K, I72V, T74S, L89M, I93LCRF01_AE
Jiamsakul (2013)R12081R12081KJ868859None   L10V, I13V, G16E, L19M, E35D, M36I, R41K, I62IV, H69K, K70KR, T74S, L89MCRF01_AE
Kiertiburanakul (2013)R73192R73192KC810468None   I13V, E35D, M36I, N37D, L63P, H69K, K70KR, T74S, L89M, I93LCRF01_AE
 R71TS109R71TS109KC921587None   I13V, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93LCRF01_AE
 R41163R41163KC970899None   H69K, T74S, V77I, L89M, I93LCRF01_AE
 R73235R73235KC810509None  G48GEI13V, K20R, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93LCRF01_AE
 X12TS034X12TS034KC994430None   L10IV, T12P, I13V, L19M, E35D, M36I, R41K, R57K, H69K, T74S, L89MCRF01_AE
 X12TS026X12TS026KC994422None   L10V, T12P, I13V, L19M, E35D, M36I, R41K, H69K, T74S, L89MCRF01_AE
 R71TS169R71TS169KC921645None   I13V, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93LCRF01_AE
 R41041R41041KC970868None   L63P, I64V, H69K, T74S, I93LCRF01_AE
 R74082R74082KC791301None   I13V, E35D, M36I, N37D, I62V, L63P, H69K, K70R, T74S, L89MCRF01_AE
 R71205R71205KC921440None   I13V, E35D, M36I, R41K, R57K, H69K, T74S, L89M, I93LCRF01_AE
 R12130R12130KC994268None   L10V, T12P, I13V, L19IM, E35D, M36I, R41K, R57K, H69K, T74S, L89MCRF01_AE
 R74183R74183KC791402None   L10V, I13V, G16E, K20R, E35D, M36I, P39PS, R41K, R57K, I62V, L63H, H69K, K70R, I72V, T74S, L89MCRF01_AE
 R74105R74105KC791324None   L10LV, G16GA, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 R71TS130R71TS130KC921607None   I13V, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 R75021R75021KC962538None   E35D, M36I, R41K, Q61E, I62IV, L63P, H69K, T74S, L89M, I93LCRF01_AE
 R73020R73020KC810556None   G17E, K20R, M36I, R41K, I62V, H69K, T74S, L89M, I93LCRF01_AE
Telan (2013)1112847611128476AB747503None   T12P, I13V, E35D, M36I, R41K, L63C, H69K, T74S, V77I, L89MCRF01_AE
Zheng (2013)VN_001VN_001JX123778None   E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Khairunisa (2014)TD18TD18KM212897None   L10V, G16E, E35D, M36I, R41K, L63T, H69K, K70R, T74S, L89M, I93LCRF01_AE
 TD32TD32KM212907None   G16E, M36I, R41K, F53V, Q61E, H69K, K70R, T74S, L89M, I93LCRF01_AE
 TD70TD70KM212931None   L10V, I13V, G16E, E35D, M36I, R41K, H69K, K70R, T74S, L89M, I93LCRF01_AE
Wallis (2014)4105741057KM458498None   L10V, I13V, M36I, R41K, I62V, L63P, H69K, K70R, T74S, L89MCRF01_AE
Zhou (2014)08mLDTD01708mLDTD017KC913743None   I13V, E35D, M36I, R41K, L63LP, H69K, T74S, L89M, I93LCRF01_AE
 09mLDTD02009mLDTD020KC913832None  L33FI13V, E35D, M36I, R41K, I62V, L63T, H69K, I72V, T74S, L89M, I93VCRF01_AE
Chin (2015)NMC20140032014003KM820409None   I15V, L19I, E35D, M36I, R41K, L63P, H69K, T74S, L89M, I93LCRF01_AE
Kotaki (2015)PJ68PJ68KJ865312None   I13V, G16E, E35D, M36I, R41K, H69K, K70R, T74S, L89M, I93LCRF01_AE
 PJ39PJ39KJ865311None   G16E, E35D, M36I, R41K, H69K, K70R, T74S, L89M, I93LCRF01_AE
 SM26SM26KJ865305None   G16E, E35D, M36I, R41K, H69K, K70R, T74S, L89M, I93LCRF01_AE
 UA31UA31KJ865346None   I13V, G16E, K20R, E35D, M36I, R41K, L63T, H69K, K70R, T74S, L89M, I93LCRF01_AE
Li (2015)SF13G267SF13G267KR188300None   E35D, M36I, R41K, I62V, H69K, T74S, L89MCRF01_AE
 SF13G253SF13G253KR188290None   K20R, E35D, M36I, R41K, L63T, H69K, K70R, I72T, T74S, L89M, I93LCRF01_AE
 SF130157SF130157KR188029None   K20R, E35D, M36I, R41K, L63T, H69K, K70KR, I72IV, T74S, L89M, I93LCRF01_AE
Li (2015)GX14S0017GX14S0017KR823270None   I13V, G16E, K20R, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 GX14S0036GX14S0036KR823282None   I13V, G16E, K20R, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 GX14S0092GX14S0092KR823298None   T12P, L19M, E35D, M36I, R41K, L63T, H69K, T74S, L89MCRF01_AE
Wang (2015)0907009070KM395760None   I13V, K20I, E35D, M36I, R41K, H69K, T74S, V77I, L89MCRF01_AE
Zhang (2015)HZ130995HZ130995KM258829None   I13IV, G16E, E35D, M36I, R41K, H69K, K70R, T74S, L89M, I93LCRF01_AE
Zhang (2015)LZ12S0002LZ12S0002KR106867None   E35D, M36I, R41K, Q61E, I62V, H69K, T74S, L89MCRF01_AE
Castley (2016)P149393022EP149393022EKT229071None   I15V, G16E, E35D, M36I, R41K, F53FC, I62V, L63P, H69K, K70R, T74S, L89M, L90LW, I93L, F99XCRF01_AE
 P149600306RP149600306RKT229108None   E35D, H69K, T74S, L89MCRF01_AE
Chow (2016)MYNBB020MYNBB020KU535910None   M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Hattori (2016)C11_673526C11-20673526-1AB864353None   I13V, K20R, E35D, M36I, R41K, L63T, H69K, I72V, T74S, L89M, I93LCRF01_AE
 C10_110997C10-51110997-1AB865403None   I13V, G17E, K20I, E35D, M36I, R41K, H69K, K70R, I72V, T74S, L89MCRF01_AE
 C12_933733C12-20933733-1AB864456None   I13V, E35D, M36I, R41K, I62V, H69K, I72V, T74S, L89MCRF01_AE
 C12_111350C12-51111350-1AB865756None   I13V, E35D, M36I, R41K, I62V, H69K, I72V, T74S, L89MCRF01_AE
 C12_111349C12-51111349-1AB865755None   I13V, E35D, M36I, R41K, I62V, H69K, I72V, T74S, L89MCRF01_AE
 C10_91_B15C10-2091_B15-1AB864547None   L10V, G16E, E35D, M36I, R41K, H69K, K70R, I72V, T74S, L89I, I93LCRF01_AE
Lam (2016)1202200212022002KR867879None   I13V, E35D, M36I, N37D, R41K, I62V, H69K, T74S, V77VI, L89MCRF01_AE
 1301200413012004KR868219None   I13V, L19V, H69K, T74S, L89MCRF01_AE
 1201201412012014KR867761None   L10I, I13V, E35D, M36I, R41K, I62V, C67CG, H69K, T74S, L89ICRF01_AE
 1301201813012018KR867868None   I13V, G16E, M36I, R41K, D60DE, H69K, K70R, T74S, L89M, I93LCRF01_AE
Saeng-Aroon (2016)117721117721LC114973None   E35D, M36I, R41K, L63P, H69K, K70R, I72V, T74S, L89M, I93LCRF01_AE
 111284111284LC114939None   I13V, K20I, E35D, M36I, N37D, R41K, H69K, T74S, L89MCRF01_AE
 116476116476LC114964None   L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93LCRF01_AE
 9267492674LC114910None   I13V, I15V, E35D, M36I, R41K, I62IV, H69K, T74S, L89MCRF01_AE
Steegen (2016)GFGPA038GFGPA038KT893185None   E35D, M36I, R41K, L63V, H69K, T74S, L89MCRF01_AE
Van Tran (2016)VI-368VI-368LC101221None   I13V, G16E, K20I, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 VI-018VI-018LC101188None   I13V, E35D, M36I, R41K, R57K, I62V, L63S, H69I, T74S, L89MCRF01_AE
 VI-384VI-384LC101233None   I13V, G16E, K20I, L33V, M36I, N37E, R41K, H69K, T74S, L89M, I93LCRF01_AE
 VI-108VI-108LC100975None   E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
 VI-209VI-209LC101069None   L19IM, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Wang (2016)90769076KT893665None  L33FI13V, E35D, M36I, R41K, I62V, L63T, H69K, I72V, T74S, L89M, I93VCRF01_AE
 1009110091KT893688None   I13V, E35D, M36I, R41K, H69K, T74S, L89M, I93LCRF01_AE
Witaningrum (2016)PB15PB15KU596484None   I15V, E35D, M36I, R41K, H69K, K70R, T74S, L89MCRF01_AE
Zhang (2016)0404804048KU871411None  L33FI13V, M36I, R57K, Q61E, H69K, K70R, T74S, L89M, I93LCRF01_AE
Zhao (2016)LS5582LS5582KT379641None   I13V, L19M, K20R, E35D, M36I, R41K, R57K, H69K, T74S, L89M, T91A, F99LCRF01_AE
 LS1473LS1473KT378936None   E35D, M36I, R41K, R57K, H69K, K70R, T74S, L89MCRF01_AE
 LS861LS861KT379901None   I13V, L19M, E35D, M36I, R41K, R57K, H69K, T74S, L89M, T91A, F99LCRF01_AE