<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation T74S
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 17
Isolates 17
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Ariyoshi (2003)JPN42JPN42A SQV104I54V, V82F, L90ML33F, I84LL10V, I13V, I15IV, G16E, K20I, E35D, M36I, N37ND, R41K, H69K, T74S, L89I, Q92KCRF01_AE
 JPN30JPN30 NFV71L90M L10V, I13V, K20T, E35D, M36I, R41K, H69K, K70R, T74S, L89ICRF01_AE
 JPN35JPN35AY900862IDV, NFV140M46I, L90M L10V, I13V, K20T, E35D, M36I, R41K, Q61H, L63P, I64V, H69K, K70R, T74S, R87X, L89M, I93LCRF01_AE
 JPN39JPN39AY900865NFV200M46I, N88SL10FI13V, K20I, E35D, M36I, R41RK, I64V, H69K, T74S, V77VI, L89M, I93LCRF01_AE
Montes (2004)MB_patBRI00_BRI706AJ577745SQV, NFV, RTV111  Q7P, I13V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, H69K, T74S, L89MCRF01_AE
Nukoolkarn (2004)238238 LPV L90M L10I, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89MCRF01_AE
Hsu (2005)BAA150627BAA150627AY870159SQV, RTV61G48V, I54IV, V82AL33F, F53L, N83DL10I, I13V, M36L, R41K, I62IV, L63P, H69K, T74S, L89IM, I93IVCRF01_AE
 BAA161419BAA161419AY870226SQV, RTV  L89MVI13V, K20I, E35D, M36I, R41K, H69K, T74SCRF01_AE
 BAA161430BAA161430AY870232IDV, SQV88G48V, I54V, V82AF53LL10I, I13V, L19LV, K20R, E35D, M36I, N37D, R41K, I62V, L63LP, H69K, A71T, T74S, L89ICRF01_AE
 BAA161439BAA161439AY870235NFV252I84IVL10F, L89VI13V, K20T, E35D, M36I, R41K, H69K, A71T, T74SCRF01_AE
 BAA161452BAA161452AY870245SQV, RTV70  I13V, E35D, M36I, R41K, I62V, H69K, T74S, L89MCRF01_AE
Baxter (2006)48-41434143-30408DQ878375PINAG48V, I54A, V82S L10V, I15V, L19I, K20R, E35D, M36I, R41K, I62V, L63V, H69K, T74S, L89M, I93LCRF01_AE
Charpentier (2011)4CP 001-045 Unknown, IDVNAL90ML33IL10V, I13V, L19F, K20T, E35D, M36I, R41K, R57K, L63P, H69K, T74S, L89ICRF01_AE
Nerrienet (2014)Q0920081Q0920081JN675744LPV M46I, I54V, V82SL24I, L33I, Q58E, L89VL10I, I13V, K20KR, E35D, M36I, N37DE, K55KR, R57K, I62V, L63P, H69K, T74SCRF01_AE
 U0401148U0401148JN675808LPV   L10V, E35D, M36I, R41K, R57K, I62IV, L63C, H69K, T74S, L89MCRF01_AE
 S0916071S0916071JN675753LPV M46I, I54V, V82F, L90M L10V, K20I, E35D, M36I, R41K, Q61H, I62V, L63C, H69K, T74S, L89ICRF01_AE
 T0622115T0622115JN675800LPV   L10LI, I13V, G16E, E35D, M36I, R41K, I62IV, L63T, E65ED, H69K, T74S, L89MCRF01_AE