<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation T74S
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 45
Isolates 45
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Chantratita (2002)VL337VL337AF172706PINAG48V, V82AF53L, L89VL10I, I13V, K20I, E35D, M36I, N37D, L63P, H69K, A71V, T74SCRF01_AE
 GEN19GEN19AF191202PINAG48VL33F, F53L, N83DL10V, I13V, G16E, K20R, E35D, M36I, P39S, R41K, H69K, K70R, T74S, L89MCRF01_AE
 G27G27AF193895PINA  I13V, K14R, I15V, K20R, E35D, M36I, N37D, R41K, H69K, T74S, L89MCRF01_AE
 G73G73AF240396PINAM46L, I84VL33I, N83DL10V, I13V, A22V, E35D, M36I, R41K, H69K, T74S, L89ICRF01_AE
 G70G70AF240394PINAG48V, I54V, V82AF53LL10I, I13V, K20I, E35D, M36I, R41K, H69K, T74S, L89ICRF01_AE
 G67G67AF240392PINAI54V, V82F, L90M L10I, I13V, K20I, E35N, M36I, R41K, L63P, H69K, T74S, L89M, I93MCRF01_AE
 G66G66AF240391PINAI54V, V82F, L90M L10I, I13V, K20I, E35N, M36I, R41K, L63P, H69K, T74S, L89M, I93MCRF01_AE
 G65G65AF240390PINAG48V, I54M, V82AL33F, F53L, N83DL10I, G16A, K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93LCRF01_AE
 G58G58AF240385PINAM46I, L90ML89VI13V, K20T, E35D, M36I, R41K, I62V, H69K, A71T, T74SCRF01_AE
 G55G55AF240382PINA  I13V, E35D, M36I, R41K, H69K, T74S, L89MCRF01_AE
Ariyoshi (2003)JPN42JPN42A SQV104I54V, V82F, L90ML33F, I84LL10V, I13V, I15IV, G16E, K20I, E35D, M36I, N37ND, R41K, H69K, T74S, L89I, Q92KCRF01_AE
 JPN30JPN30 NFV71L90M L10V, I13V, K20T, E35D, M36I, R41K, H69K, K70R, T74S, L89ICRF01_AE
 JPN35JPN35AY900862IDV, NFV140M46I, L90M L10V, I13V, K20T, E35D, M36I, R41K, Q61H, L63P, I64V, H69K, K70R, T74S, R87X, L89M, I93LCRF01_AE
 JPN39JPN39AY900865NFV200M46I, N88SL10FI13V, K20I, E35D, M36I, R41RK, I64V, H69K, T74S, V77VI, L89M, I93LCRF01_AE
Montes (2004)MB_patBRI00_BRI706AJ577745SQV, NFV, RTV111  Q7P, I13V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, H69K, T74S, L89MCRF01_AE
Nukoolkarn (2004)238238 LPV L90M L10I, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89MCRF01_AE
Chantratita (2005)14-008414-0084DQ130460PINAI54A L10V, I13V, K20V, E35N, M36I, R41K, I62V, L63P, H69K, A71L, T74SCRF01_AE
 14-014614-0146DQ130511PINAM46I, I54V, L76V, V82FL33FW6R, L10I, E35D, M36I, R41K, K55R, Q61H, L63P, H69K, T74S, L89M, I93LCRF01_AE
 G522G522DQ130114PINAM46I, L90MQ58EL10I, I13V, I15V, K20T, E35D, M36I, R41K, I62V, L63P, H69K, A71V, T74S, V77I, V82I, L89I, I93L, L97MCRF01_AE
 G531G531DQ130121PINAG48V L10I, I13V, E35D, M36I, R41K, H69K, K70R, T74S, L89ICRF01_AE
 G562G562DQ130135PINA  I13V, I15V, E35D, M36I, N37D, R41K, H69K, T74S, L89MCRF01_AE
 G590G590DQ130153PINAI54V L10V, I13V, K20V, E35N, M36I, R41K, I62V, L63P, H69K, A71L, T74SCRF01_AE
 G614G614DQ130166PINAM46I, I54A, V82A L10I, I13V, G16E, K20I, E35D, M36I, R41K, L63T, I64L, H69K, T74S, L89MCRF01_AE
 G635G635DQ130180PINA  I13V, K20I, E35D, M36I, R41K, H69K, T74S, L89MCRF01_AE
 G694G694DQ130209PINA  I13V, K20I, E35N, M36I, N37D, R41K, H69K, T74S, L89MCRF01_AE
 G724G724DQ130222PINA  I13V, K20I, E35D, M36I, R41K, R57K, H69K, T74S, L89ICRF01_AE
 G734G734DQ130228PINAG48V, I54A, V82A I13V, K20I, E35D, M36I, R41K, I62V, L63P, H69K, K70R, T74S, L89ICRF01_AE
 NP144NP144DQ130258PINAG48V, V82AL33I, F53LL10I, I13V, E35D, M36I, R41K, H69K, T74S, L89ICRF01_AE
 NP145NP145DQ130259PINA  L10V, I13V, G16E, K20R, E35D, M36I, P39S, R41K, H69K, K70R, T74S, L89MCRF01_AE
 NP164NP164DQ130268PINAM46IL33I, N83DL10V, I13V, K14N, G16A, K20T, A22V, E35D, M36I, R41K, I62V, L63V, H69K, K70R, T74S, V82I, L89I, I93LCRF01_AE
 NP174NP174DQ130278PINA  L10V, I13V, K20T, E35D, M36I, N37D, R41K, D60E, H69K, A71T, T74S, L89ICRF01_AE
 NP183NP183DQ130287PINAL90ML89VI13V, K20T, E35D, M36I, R41K, I62V, L63P, H69K, I72M, T74S, V77I, V82ICRF01_AE
 NP194NP194DQ130298PINA  E35D, M36I, R41K, I62V, H69K, T74S, L89MCRF01_AE
 NP260NP260DQ130342PINA  K20R, E35D, M36I, R41K, L63P, H69K, T74S, L89M, I93LCRF01_AE
 NP267NP267DQ130349PINAD30NL10F, N88DI13V, G17E, K20T, E35D, M36I, R41K, L63P, H69K, A71V, T74S, L89TCRF01_AE
Hsu (2005)BAA150627BAA150627AY870159SQV, RTV61G48V, I54IV, V82AL33F, F53L, N83DL10I, I13V, M36L, R41K, I62IV, L63P, H69K, T74S, L89IM, I93IVCRF01_AE
 BAA161419BAA161419AY870226SQV, RTV  L89MVI13V, K20I, E35D, M36I, R41K, H69K, T74SCRF01_AE
 BAA161430BAA161430AY870232IDV, SQV88G48V, I54V, V82AF53LL10I, I13V, L19LV, K20R, E35D, M36I, N37D, R41K, I62V, L63LP, H69K, A71T, T74S, L89ICRF01_AE
 BAA161439BAA161439AY870235NFV252I84IVL10F, L89VI13V, K20T, E35D, M36I, R41K, H69K, A71T, T74SCRF01_AE
 BAA161452BAA161452AY870245SQV, RTV70  I13V, E35D, M36I, R41K, I62V, H69K, T74S, L89MCRF01_AE
Nerrienet (2014)Q0920081Q0920081JN675744LPV M46I, I54V, V82SL24I, L33I, Q58E, L89VL10I, I13V, K20KR, E35D, M36I, N37DE, K55KR, R57K, I62V, L63P, H69K, T74SCRF01_AE
 U0401148U0401148JN675808LPV   L10V, E35D, M36I, R41K, R57K, I62IV, L63C, H69K, T74S, L89MCRF01_AE
 S0916071S0916071JN675753LPV M46I, I54V, V82F, L90M L10V, K20I, E35D, M36I, R41K, Q61H, I62V, L63C, H69K, T74S, L89ICRF01_AE
 U0302042U0302042JN675764LPV M46I, I54V, V82A, L90ML10F, L33I, K43T, N88DV11L, I13V, L19LV, K20V, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71V, T74S, L89T, T91ACRF01_AE
 T0622115T0622115JN675800LPV   L10LI, I13V, G16E, E35D, M36I, R41K, I62IV, L63T, E65ED, H69K, T74S, L89MCRF01_AE