<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation T74A
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 16
Isolates 16
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Chantratita (2005)14-010314-0103DQ130473PINA L33F, I54C, N83DI13V, G16A, K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74A, L89MCRF01_AE
 G602G602DQ130159PINAI54V, I84VN83DL10I, I13V, A22V, L33M, E35D, M36I, R41K, I62V, H69K, T74A, L89ICRF01_AE
 G625G625DQ130174PINA  I13V, G17E, E34A, E35D, M36I, R41K, Q61H, L63T, H69K, K70R, I72T, T74A, L89MCRF01_AE
 NP234NP234DQ130319PINAI84V L10V, I13V, K20R, E35D, M36I, R41K, R57K, I62V, L63P, H69K, T74A, L89ICRF01_AE
 NP321NP321DQ130399PINAN88SL10FI13V, K20I, E35D, M36I, R41K, I62V, L63P, H69K, T74A, L89M, I93LCRF01_AE
 NP324NP324DQ130402PINAG48V, I50V, I54S, V82AL33F, F53L, N83DL10I, I13V, K20R, E34V, E35D, M36I, I62V, I66F, H69K, T74A, L89MCRF01_AE
 NP327NP327DQ130404PINAI54V, V82AK43T, N83DL10I, I13V, G16E, K20R, E35D, M36I, R41K, K55R, I62V, H69K, K70R, T74A, L89MCRF01_AE
Hsu (2005)BAA154760BAA154760AY870162NFV113  K20I, E35N, M36I, N37D, R41K, L63P, H69K, T74A, L89M, I93LCRF01_AE
 BAA161422BAA161422AY870228IDV317M46ML, I54IV, V82F L10LI, I13V, K20KI, E35D, M36I, R41K, I62V, H69K, T74A, L89MCRF01_AE
 BAA161424BAA161424AY870229IDV91 L89MVI13V, K20KI, E35D, M36I, R41K, I62V, H69K, K70R, T74ACRF01_AE
Baxter (2006)48-41134113-30319DQ878344PINAI54V, V82A L10I, I13V, G16E, L19I, K20I, E35D, M36I, P39S, R41K, D60DE, I62V, H69K, K70R, A71IV, I72V, T74A, L89ICRF01_AE
Charpentier (2011)CR-50CR-50FJ688256PINAM46IL10FK20I, E35D, M36I, N37D, R41K, I62IV, L63T, H69K, T74A, V77VI, I85IV, L89M, I93LCRF01_AE
Ferradini (2011)40739PRHM026302LPV24V82A L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63C, H69K, T74A, L89MCRF01_AE
Nerrienet (2014)S0613189S0613189JN675750LPV V82A L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63C, H69K, T74A, L89MCRF01_AE
 T0506285T0506285JN675754LPV M46I, I47V, I54V, I84VL10F, L24IK20I, E35N, M36I, K55R, I62V, L63P, H69K, A71V, T74A, L89M, I93LCRF01_AE
 U0519246U0519246JN675768LPV V82A L10I, I13V, G16E, K20R, E35D, M36I, R41K, L63T, H69K, T74A, L89M, I93VCRF01_AE