<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L63V
Rx PI-naive
IncludeMixtures No
References 64
Patients 140
Isolates 141
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Fonjungo (2002)CM133CM133AF406711None   I13V, E35N, M36I, N37D, R41K, L63V, I64M, H69K, L89M, I93LCRF01_AE
Hsu (2005)LYH_AY870199BAA161383AY870199None   L10I, I13V, G16E, K20KR, E35D, M36I, N37NK, P39S, R41K, L63V, H69K, I72V, L89MCRF01_AE
Ly (2005)NL_KHM_CD8KHM_CD8DQ013638None   I13V, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Tee (2005)03MYKL142003_1420AY904540None   I13V, K20R, M36I, R41K, L63V, H69K, V82I, L89MCRF01_AE
 04MYKLLYY032804LYY0328AY904576None   I13V, K20R, M36I, R41K, L63V, H69K, L89MCRF01_AE
 03MYKL136203_1362AY904535None   L10V, I13V, G16E, E35D, M36I, R41K, L63V, H69K, K70R, L89MCRF01_AE
Watanaveeradej (2006)99TH_R326599_R3265AY945732None   I13V, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Gatanaga (2007)C03-51110060-1C03-51110060-1AB640160None   E35D, M36I, R41K, Q61E, L63V, H69K, L89MCRF01_AE
 C04-51110192-1C04-51110192-1AB640292None   I13V, K20I, E35D, M36I, R41K, L63V, I64M, H69K, L89MCRF01_AE
Liu (2007)fj60fj60EF432690None   L10I, I13V, G16E, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Bao (2008)YUN01-38YUN01-38AM886214None   L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63V, H69K, L89M, I93LCRF01_AE
Chang (2008)TW10386aTW10386a None   L10I, I13V, E35D, M36I, R41K, L63V, L89MCRF01_AE
 TW10405aTW10405a None   L10I, I13V, E35D, M36I, R41K, L63V, L89MCRF01_AE
Delgado (2008)GH_019GH_019EU177896None   I13V, K20R, M36I, R41K, L63V, I64M, H69K, L89MCRF01_AE
Aghokeng (2009)CDB0003CDB0003GU191634None   L10V, I13V, K14KN, I15V, G16A, E35D, M36I, R41K, I62V, L63V, I64L, H69K, L89MCRF01_AE
Ayouba (2009)FD0492FD0492PIGQ352109None   L10V, T12TA, I13V, I15V, E35D, M36I, R41K, R57K, L63V, H69K, L89MCRF01_AE
Bartolo (2009)HDP11201AOHDP112EU068236None   L10I, I13V, E35D, M36I, R41K, L63V, C67Y, H69K, L89MCRF01_AE
Ishizaki (2009)A127A127FJ007162None   L10I, I13V, G16E, K20I, M36I, R41K, L63V, H69K, L89MCRF01_AE
 A174A174gFJ007190None   L10I, I13V, K14R, G16E, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 A482A482FJ007339None   I13V, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Vercauteren (2009)pt15863841341890GQ399438None   I13V, I15V, M36I, R41K, L63V, H69K, V82I, L89MCRF01_AE
 pt6798Df8tOm8ngGQ400345None   I13V, E35D, M36I, R41K, R57K, L63V, I64L, H69K, K70R, I72V, L89MCRF01_AE
Bonura (2010)1193_881193_88GU969548None  V11IL10V, T12A, I13V, G16E, K20I, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Han (2010)LN179LN179FJ531434None   I13V, G16E, L19V, E35D, M36I, R41K, L63V, H69K, K70R, L89M, I93LCRF01_AE
 LN106LN106FJ531447None   I13V, G16E, L19V, E35D, M36I, R41K, L63V, H69K, K70R, L89M, I93LCRF01_AE
Hattori (2010)F07-20702F07-20702AB866459None   I13V, G16E, K20R, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 C08-51110635C08-51110635AB865042None   L10I, I13V, I15V, E35D, M36I, N37D, R41K, L63V, H69K, L89MCRF01_AE
 C08-51110782C08-51110782AB865188None   L10I, I13V, E35D, M36I, R41K, L63V, H69K, L89M, L97ICRF01_AE
Ndembi (2010)DT1515_04_P11515GQ409600None   E35D, M36I, R41K, R57K, L63V, H69K, L89MCRF01_AE
Phan (2010)O935O935AB519506None   L10V, T12P, I13X, G16E, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Hamers (2011)CP076301742CP076301742HQ993732None   I15IV, G16E, K20R, E35D, M36I, R41K, R57K, L63V, H69K, L89M, I93LCRF01_AE
Lazaro (2011)DT-M10DT-M10HQ542696None   I13V, I15V, E35D, M36I, R41K, R57K, L63V, I64M, H69K, L89M, I93LCRF01_AE
Su (2011)LZ2168LZ2168HQ588231None   I13V, G16E, K20R, E35D, M36I, R41K, L63V, H69K, I72V, L89M, I93LCRF01_AE
Afonso (2012)ANG14ANG14JN937029None   E35D, M36I, R57K, L63V, H69K, K70R, L89MCRF01_AE
An (2012)10LNA26410LNA264JX960622None   L19I, E35D, M36I, R41K, L63V, H69K, V82I, L89M, I93LCRF01_AE
Chen (2012)YN10DH0145YN10DH0145JQ658764None   I15V, E35D, M36I, R41K, L63V, H69K, T74TACRF01_AE
De Gascun (2012)IRL25181IRL25181JN622221None   Q7QR, L10V, I13V, G16E, K20I, E35D, M36I, N37NY, R41K, K45KN, L63V, H69K, G78GA, I85IM, L89MCRF01_AE
 IRL54561IRL54561JN622233None   L10V, T12A, I13V, G16E, K20I, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Dvali (2012)R050R050GQ268456None   E35D, M36I, R41K, Q61E, L63V, I64M, H69K, L89M, I93LCRF01_AE
Thao (2012)HCMC_173HCMC_173JN786442None   L10I, I13V, G16E, M36I, R41K, L63V, H69K, K70R, L89IMCRF01_AE
 HCMC_162HCMC_162JN786432None   L10LI, I13V, I15IV, K20KR, M36I, N37ND, R41K, L63V, I64M, H69K, L89M, I93LCRF01_AE
Trinh (2012)VN-66VN-66HQ876704None   L19I, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Frentz (2013)EHR-68427EHR-68427JX300692None   L10V, I15V, K20R, E35D, M36I, R41K, R57K, L63V, H69KCRF01_AE
 EHR-77470EHR-77470JX300874None   L10V, I13V, G16E, E35D, M36I, R41K, L63V, H69K, K70R, L89MCRF01_AE
 EHR-80323EHR-80323JX300907None   L10V, I13V, K14KR, E35D, M36I, R41K, R57RK, L63V, C67CY, H69K, L89MCRF01_AE
Han (2013)10LN30057110LN300571KC888272None   E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 11LN30083811LN300838KC888401None   E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 11LN30085311LN300853KC888410None   E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 09LN30044409LN300444KC888218None   E35D, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
 11LN32001811LN320018KC888420None   I13V, L19M, E35D, M36I, R41K, L63V, H69K, V82I, L89MCRF01_AE
 10LN30061610LN300616KC888290None   E35D, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
 09SC20109SC201KC888691None   E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 11LN30069011LN300690KC888339None   T12P, L19M, E35D, M36I, R41K, L63V, H69K, K70R, L89MCRF01_AE
 11LN30070611LN300706KC888347None  L33FI13V, L19M, K20R, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
Hassan (2013)RS09000918RS09000918HQ441662None   I13V, E35D, M36I, R41K, R57K, L63V, H69K, K70KR, L89MCRF01_AE
Hawke (2013)1625628616256286KC237974None   L10V, I13V, I15V, G16E, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Jiamsakul (2013)R72010R72010KJ868889None   L10I, I13V, G16E, E35D, M36I, R41K, L63V, H69K, I72VCRF01_AE
Kiertiburanakul (2013)R42083R42083KC971039None   I13V, L63V, I64M, H69K, V82I, L89MCRF01_AE
 R73122R73122KC810408None   I13V, I15V, E35D, M36I, R41K, R57K, L63V, H69K, V82I, L89MCRF01_AE
 R73238R73238KC810512None   L10LV, I13V, I15V, G16E, E35D, M36I, R41K, L63V, H69KCRF01_AE
 R74170R74170KC791389None   L10I, I13V, E35D, M36I, R41K, L63V, H69K, L89M, G94DCRF01_AE
 R71129R71129KC921841None   I13V, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 R73112R73112KC810399None   I13V, K14KR, G17D, K20R, E35D, M36I, R41K, K45KR, L63V, H69K, K70KR, L89MCRF01_AE
 R74125R74125KC791344None   L10I, T12TI, I13V, G16GE, E35D, M36I, R41K, R57RK, L63V, H69K, L89IM, I93IVCRF01_AE
 R71TS267R71TS267KC921736None   L10V, D25Y, M36I, R41K, L63V, I64L, H69K, K70R, I72V, L89M, I93LCRF01_AE
 R74178R74178KC791397None   L10I, I13V, G16E, E35D, M36I, N37ND, R41K, R57K, D60E, Q61E, L63V, H69K, L89MCRF01_AE
 R73104R73104KC810392None   L10V, I13V, G16E, K20R, E35D, M36I, R41K, D60E, L63V, H69K, L89M, I93L, F99SCRF01_AE
 R74106R74106KC791325None   E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 R73139R73139KC810422None   L10IV, I13V, I15IV, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 R71147R71147KC921423None   L10V, I13V, K14R, I15V, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 R12186R12186KC994312None   L10I, T12TA, I13V, G16E, E35D, M36I, N37ND, P39PS, R41K, L63V, H69K, L89MCRF01_AE
 R41136R41136KC970887None   I15V, K20R, D29N, E34K, E35D, M36I, R41K, W42R, L63V, H69K, L89M, I93LCRF01_AE
 R71TS062R71TS062KC921541None   L10I, T12A, I13V, E35D, M36K, R41K, L63V, H69K, L89MCRF01_AE
 R71041R71041KC921795None   L10I, I13V, G16E, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 R73170R73170KC810447None   L10I, I13V, K14R, G16E, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 R73228R73228KC810502None   L10V, I15V, G16E, K20R, E35D, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
 R75035R75035KC962527None   I15V, G16E, K20R, E35D, M36I, R41K, L63V, H69K, I72V, I93LCRF01_AE
 R72019R72019KC867570None   I13V, E35D, M36I, P39S, R41K, L63V, H69K, L89MCRF01_AE
 R74081R74081KC791300None   L10I, I13V, G16GE, L19I, E35D, M36I, R41K, R57RK, L63V, H69K, L89MCRF01_AE
 R71TS120R71TS120KC921597None   L10I, I13V, G16E, L23K, E35D, M36I, R41K, L63V, C67Y, H69K, L89ICRF01_AE
 R74038R74038KC791258None   L10I, I13V, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 R71138R71138KC921422None  V11IL10M, I13V, G16E, E35D, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
 R74147R74147KC791366None   L10I, I13V, I15V, G16A, E35D, M36I, R41K, L63V, H69K, L89M, I93VCRF01_AE
 R73174R73174KC810451None   L10IM, I13V, G16GA, E35D, M36I, R41K, L63V, C67S, H69K, L89MCRF01_AE
 R71006R71006KC921771None   L10I, I13V, E35D, M36I, R41K, L63V, H69K, I72V, L89MCRF01_AE
 R74037R74037KC791257None   L10IV, I13V, G16GE, M36I, R41K, L63V, C67CG, H69K, I72IV, L89ICRF01_AE
 R74199R74199KC791417None   L10I, I13V, G16E, E35D, M36I, R41K, L63V, H69K, K70R, L89MCRF01_AE
 R71232R71232KC921462None   L10I, I13V, G16E, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 R72202R72202KC857023None   I13V, I15IV, G16E, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Li (2013)22302230JQ302696None   E35D, M36I, R41RK, L63V, H69K, L89MCRF01_AE
 22512251JQ302714None   I15V, G16E, E35D, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
Ong (2013)08MYKL04908MYKL049KC181264None   L10I, I13V, I15V, K20R, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 09MYKL07309MYKL073KC181289None   I13V, L63V, I64M, H69K, V82I, L89MCRF01_AE
 08MYKL00208MYKL002KC181245None  L33FI13V, E35D, R41K, L63V, H69K, L89MCRF01_AE
Telan (2013)1105283811052838AB747454None   T12I, I13V, G16E, K20R, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
 1104283811042838AB747471None   T12I, I13V, G16E, K20R, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
Chen (2014)YN021YN021HG421466None   E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Hassan (2014)RS09000841RS09_841KC568498None   I13V, E35D, M36I, R41K, R57K, I62V, L63V, I64M, H69K, L89MCRF01_AE
Lee (2014)MBA1302MBA1302KJ906992None   L10I, I13V, T26TS, E35D, M36I, R41K, R57K, L63V, I64IM, H69K, L89MCRF01_AE
Meixenberger (2014)07-0089507-00895KJ770522None   L10V, I13V, K14KR, E35D, M36I, R41K, R57RK, L63V, C67CY, H69K, L89MCRF01_AE
Schwem (2014)NIHA_42NIHA_42KX184153None   K20R, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
Zhou (2014)08mLDTD02208mLDTD022KC913746None   I13V, K20R, E35D, M36I, R41K, R57K, L63V, H69K, L89MCRF01_AE
 08mLDTD01208mLDTD012KC913738None   I13V, G16E, K20I, E35D, M36I, R41K, L63V, I64M, H69K, K70R, L89MCRF01_AE
Alexiev (2015)999_0809999_0809JQ259177None   L10V, I13V, G16E, E35D, M36I, R41K, L63V, H69K, K70R, L89MCRF01_AE
Dauwe (2015)AE_8465AE_8465KT863680None  L33IL10V, I13V, G16E, K20R, E35D, M36I, R41K, D60E, L63V, H69K, L89M, I93LCRF01_AE
 AE_01_82AE_01_82KT863621None   L10I, I13V, G16E, T31P, E35N, M36I, R41K, L63V, H69K, L89MCRF01_AE
Li (2015)SF130055SF130055KR188007None   I13V, L19M, E35D, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
 SF13G212SF13G212KR188270None   I13V, G16E, L19V, E35D, M36I, R41K, K45R, L63V, H69K, K70R, L89M, I93LCRF01_AE
Li (2015)BJ14S0011BJ14S0011KR823044None   L10V, I13V, G16E, L19M, E35D, M36I, R41K, L63V, H69K, L89M, I93ILCRF01_AE
 NN13S0051NN13S0051KR823700None   I13V, G16E, L19V, K20R, E35D, M36I, R41K, L63V, H69K, K70R, L89M, I93LCRF01_AE
Wu (2015)BZAFKB0570BZAFKB0570KP992407None   I15IV, G16E, E35D, M36I, R41K, L63V, H69K, K70KQ, L89M, I93LCRF01_AE
Zhang (2015)NN13S0051NN13S0051KR106979None   I13V, G16E, L19V, K20R, E35D, M36I, R41K, L63V, H69K, K70R, L89M, I93LCRF01_AE
Boillot (2016)VIR26VIR26KT315991None   L10I, I13V, G16E, E35D, M36I, P39S, R41K, L63V, H69K, L89MCRF01_AE
Castley (2016)P131089004DP131089004DKT228929None   L10M, I13V, G17E, E35D, M36I, R41K, L63V, H69K, N83X, L89MCRF01_AE
 R050336872R050336872KT229346None   L10V, I13V, G17E, E35D, M36I, R41K, R57K, L63V, H69K, V77VI, L89MCRF01_AE
Hattori (2016)C11_111154C11-51111154-1AB865560None   T12P, I13V, I15V, G16E, K20R, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
 C10_111121C10-51111121-1AB865527None   L10I, I13V, G16E, E35D, M36I, R41K, L63V, H69K, L89M, F99LCRF01_AE
Lam (2016)1202201212022012KR867766None   L10I, I13V, G16E, E35D, M36I, R41K, D60E, L63V, H69K, L89MCRF01_AE
 90120119012011KR867836None   T12A, G16E, L19I, M36I, D60E, I62V, L63V, I64L, H69K, L89MCRF01_AE
 1202100212021002KR867776None   L10I, I13V, I15L, G16E, K20I, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Lu (2016)SJ13226SJ13226KU378042None   I13V, I15V, E35D, M36I, R41K, L63V, H69K, K70R, L89MCRF01_AE
 QHD13AD025QHD13AD025KU378041None   I13V, I15V, E35D, M36I, R41K, L63V, H69K, K70R, L89MCRF01_AE
 13HD06513HD065KU378038None   I13V, I15V, E35ED, M36I, R41K, L63V, H69K, K70R, L89M, I93LCRF01_AE
 TS130523TS130523KU378045None   I13IV, I15V, L19M, E35D, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
 QHD13AD009QHD13AD009KU378040None   T12TP, I13V, I15V, G16GE, L19LI, E35D, M36I, R41K, I62IV, L63V, H69K, K70R, L89MCRF01_AE
Pouran Yousef (2016)345407-00895KX466342None   L10V, I13V, K14KR, E35D, M36I, R41K, R57RK, L63V, C67CY, H69K, L89MCRF01_AE
Saeng-Aroon (2016)7022370223LC114860None   I13V, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Steegen (2016)GFGPA038GFGPA038KT893185None   E35D, M36I, R41K, L63V, H69K, T74S, L89MCRF01_AE
Van Tran (2016)VI-104VI-104LC100971None   I13V, K14R, M36I, R41K, L63V, H69K, L89ICRF01_AE
 VI-164VI-164LC101028None   L10I, I13V, I15V, M36I, R41K, L63V, H69K, L89MCRF01_AE
 VI-328VI-328LC101167None   L10I, I13V, G16E, E35D, M36I, R41K, K45R, L63V, H69K, L89MCRF01_AE
 VI-339VI-339LC101177None   I15V, E35D, M36V, N37D, R41K, L63V, H69K, I93LCRF01_AE
Wang (2016)1100311003KT893692None   I13V, K14R, E35D, M36I, R41K, I62V, L63V, H69R, I72V, V82I, L89MCRF01_AE
 90499049KT893661None   I13V, K20R, E35D, M36I, R41K, R57K, L63V, H69K, L89MCRF01_AE
Zeh (2016)3000850_053000850_05KU248679None   E35D, M36I, R41K, R57K, L63V, H69K, L89MCRF01_AE
Zhao (2016)LS5635LS5635KT379654None   G16E, L19I, E35D, M36I, N37D, R41K, I62V, L63V, H69K, V82I, L89M, I93LCRF01_AE
 LS5518LS5518KT379617None   G16E, L19V, E35D, M36I, R41K, L63V, H69K, K70R, I72V, L89M, I93LCRF01_AE
 LS5720LS5720KT379677None   Q2QH, G16E, L19V, E35D, M36I, R41K, L63V, H69K, K70R, I72V, L89M, I93LCRF01_AE
 LS5690LS5690KT379669None   G16E, L19V, E35D, M36I, R41K, L63V, H69K, K70R, I72V, L89M, I93LCRF01_AE
 LS1386LS1386KT378884None   L10V, I13V, K14R, G16E, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Zain (2017)HIVDR028HIVDR028KU894658None   K14E, G16E, M36I, I62V, L63V, E65K, H69K, V82I, L89M, I93LCRF01_AE