<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L63T
Rx PI-naive
IncludeMixtures No
References 48
Patients 127
Isolates 129
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Hsu (2005)BAA157668BAA157668AY870174None   L10LV, I13V, K14KR, I15V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
Ly (2005)NL_KHM_CA22KHM_CA22DQ013530None   L10I, I13V, M36I, R41K, L63T, H69K, K70RCRF01_AE
 NL_KHM_CA63KHM_CA63DQ013569None   L10I, I13V, M36I, R41K, L63T, H69K, L89LMCRF01_AE
 NL_KHM_CD11KHM_CD11DQ013641None   I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 NL_KHM_CD7KHM_CD7DQ013637None  V11IL10I, I13V, K14R, M36I, R41K, L63T, H69K, L89MCRF01_AE
Tee (2005)03MYKL135303_1353AY904531None   I15V, G16E, E35D, M36V, R41K, L63T, H69K, K70R, L89MCRF01_AE
 03MYKL135403_1354AY904532None   L10I, K20R, E35D, M36I, R41K, L63T, H69K, L89M, T91NCRF01_AE
Baker (2007)P0018P0018-240105EF186133None   I13V, K14R, I15V, E35D, M36L, N37D, R41K, L63T, H69K, V77I, L89MCRF01_AE
Church (2008)347758P347758PEU380724None   I13V, G16E, E35D, M36I, R41K, R57K, L63T, I64V, H69KCRF01_AE
Holguin (2008)SP41-58559SP41-58559EU342821None   T12S, K14R, I15V, L19V, K20R, M36I, R41K, R57K, Q61H, L63T, H69K, L89M, I93LCRF01_AE
Ntemgwa (2008)775004CA7750EU220698None   L10V, I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63T, H69K, K70R, L89MCRF01_AE
Sirivichayakul (2008)BED-49BED-49PrJQ364299None   T12P, I13V, K20R, E35D, M36I, R41K, R57K, L63T, H69K, L89MCRF01_AE
 NBC-45NBC-45PrJQ364343None   E35D, M36I, R41K, L63T, H69K, V82I, L89M, I93LCRF01_AE
Auwanit (2009)23AE-PR23FJ463516None   I13V, I15V, Q18E, E35D, M36I, R41K, R57K, L63T, H69K, L89MCRF01_AE
 95AE-PR95FJ463528None   I13IV, I15V, Q18E, E35D, M36I, R41K, R57K, Q58T, L63T, H69K, L89MCRF01_AE
 104AE-PR104FJ463530None   L10I, I13V, I15V, G16E, K20E, E35D, M36I, R41K, G51*R, L63T, H69K, K70R, L89MCRF01_AE
 130AE-PR130FJ463540None   L10I, I13V, I15V, G16E, E35D, M36I, R41K, L63T, H69K, K70R, L89MCRF01_AE
Ayouba (2009)FD0526FD0526PIGQ352076None   L10V, I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
Eshleman (2009)K20527W208-101565FJ389121None   I13V, K20T, E35D, M36I, R41K, K45R, R57K, D60E, L63T, H69K, L89MCRF01_AE
Ishizaki (2009)A2_129A2_129FJ007011None   E35D, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
 A233A233aFJ007224None   I13V, E35D, M36I, R41K, L63T, H69K, I72T, L89MCRF01_AE
Vercauteren (2009)pt18012498506932GQ399223None   I13IV, I15V, E35D, M36I, R41K, R57K, L63T, H69K, L89MCRF01_AE
Chin (2010)C182C182GQ290719None   L10I, I13V, E35D, M36I, R41K, L63T, H69K, L89M, L97ICRF01_AE
Djoko (2010)680CD0639FR666680None   I13V, K14T, G16E, E35D, M36I, P39AT, R41K, K45R, R57K, I62V, L63T, I64IV, E65D, H69R, L89MCRF01_AE
Zolfo (2010)A14013A 14013 M30HM565665None   T12A, K20R, M36I, R41K, D60E, L63T, I64L, H69K, L89M, I93LCRF01_AE
 A13748A 13748 M18HM565699None   L10I, I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
  A 13748 M24HM565637None   L10I, I13V, E35D, M36I, R41K, K55KR, L63T, H69K, L89MCRF01_AE
 A14549A 14549 M18HM565713None   L10I, I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 A14109A 14109 RSHM565720None   I13V, E35D, M36I, K45R, R57K, L63T, H69K, L89M, T91VCRF01_AE
  A 14109 M18HM565627None   I13V, G16GE, E35D, M36I, K45R, R57K, L63T, H69K, L89M, T91VCRF01_AE
Avi (2011)086u086uGQ926649None   L10I, I13V, K14R, E35D, M36I, R41K, D60E, L63T, I64L, H69K, L89M, I93LCRF01_AE
Bontell (2011)Pat04508.VL772HsHQ852871None   L10I, I13V, G16E, L19LI, E35D, M36I, R41K, L63T, H69K, L89ICRF01_AE
 Pat00509.VL983UsHQ852911None   G16E, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
Bunupuradah (2011)pt001pt001Pr None   I13V, G16E, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
Dean (2011)IVVI0259IVVI0259JQ312362None   T12P, I13V, K14R, Q18H, E35D, M36I, P39S, R41K, L63T, H69K, V82VI, L89MCRF01_AE
 IVVI0337IVVI0337JQ312367None   T12P, I13V, K14R, Q18H, E35D, M36I, P39S, R41K, L63T, H69K, L89MCRF01_AE
 IVVI7396IVVI7396JQ312421None   L10V, K14R, G16E, M36I, N37D, R41K, L63T, H69K, L89M, I93LCRF01_AE
Lazaro (2011)VT-M22VT-M22HQ542650None   I13V, E35D, M36I, N37D, R41K, L63T, E65D, H69K, L89MCRF01_AE
 DT-M21DT-M21HQ542706None   T12A, I13V, E35D, M36I, R41K, K45R, L63T, H69K, V82I, L89MCRF01_AE
Ng (2011)HM069HM069HQ539098None   E35D, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
 HM149HM149HQ539174None   L10I, E35D, M36I, R41K, L63T, C67H, H69K, L89MCRF01_AE
Su (2011)GXNN7478GXNN7478HQ588273None   G16E, E35D, M36I, R41K, L63T, H69K, K70R, I72T, L89M, I93LCRF01_AE
An (2012)09LNA04109LNA041JX960618None   L19I, E35D, M36I, R41K, L63T, H69K, V82I, L89M, I93LCRF01_AE
 10LNA10510LNA105JX960626None   I13V, G16E, L19M, K20R, E35D, M36I, R41K, K45R, I62V, L63T, H69K, V82I, L89M, I93LCRF01_AE
Chen (2012)YN10DH0100YN10DH0100JQ658721None   G16E, L19M, E35D, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
Karlsson (2012)SE_176SE_176JQ698788None   L10I, I13V, G16E, E35D, M36I, R41K, L63T, H69Q, I72V, L89MCRF01_AE
Rolland (2012)AA065a07LAA065a07LJX447424None   I13V, G16E, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 AA091a03LAA091a03LJX447738None   I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 AA113a_LH8AA113a_LH8JX448084None   T12I, I13V, G16E, E35D, M36I, R41K, L63T, H69K, K70R, I72T, L89M, T91VCRF01_AE
Ssemwanga (2012)3683HR3683HRJF800225None   I13V, I15V, E35D, M36I, R41K, R57K, D60E, L63T, H69K, L89MCRF01_AE
Tran (2012)HPA013HPA013AB690876None   L10I, I13V, G16E, E35D, M36I, R41K, L63T, H69K, I72IT, P79PS, L89MCRF01_AE
 HPA171HPA171AB690894None   L10I, I13V, G16E, E35D, M36I, R41K, I62V, L63T, H69K, L89MCRF01_AE
 HPA409HPA409AB690942None   L10LI, I13V, G16E, E35D, M36I, R41K, L63T, H69K, L89ICRF01_AE
 HPA423HPA423AB690944None   I13V, K20R, E35D, M36I, N37D, R41K, L63T, H69K, I72T, L89MCRF01_AE
Yang (2012)37693769JQ617245None   W6WL, L10LI, I13V, G16A, E35D, M36IL, N37DE, R41RK, K43KR, L63T, E65ED, H69K, K70R, I72IMT, L89MCRF01_AE
Yang (2012)GZ051GZ051JN848839None   L10I, I13V, G16E, E35D, M36I, P39PT, R41K, K45R, L63T, H69K, L89MCRF01_AE
 GZ093GZ093JN848861None   I13V, M36I, R41K, R57K, L63T, H69R, L89MCRF01_AE
 GZ109GZ109JN848866None   E35D, M36I, R41K, R57K, L63T, H69R, L89M, I93LCRF01_AE
 GZ134GZ134JN848875None   I13V, E35D, M36I, R41K, R57K, L63T, H69K, I72IT, L89MCRF01_AE
 GZ096GZ096JN848891None   I13V, E35D, M36I, R41K, K45R, R57K, L63T, G68GE, H69KR, L89MCRF01_AE
 GZ108GZ108JN848893None   E35D, M36I, R41K, R57K, L63T, H69R, L89M, I93LCRF01_AE
 GZ252GZ252JN848918None   I13V, G16E, L19I, K20R, E35D, M36I, R41K, L63T, H69K, K70R, L89MCRF01_AE
Zeng (2012)CN0269CN0269JQ028202None   E35D, M36I, R41K, L63T, H69R, L89M, I93LCRF01_AE
 CN0900CN0900JQ028213None   I13V, G17E, K20R, M36I, L63T, H69K, L89M, I93LCRF01_AE
 CN0310CN0310JQ028406None   E35D, M36I, R41K, L63T, H69R, L89M, I93LCRF01_AE
Avidor (2013)21752175KC184364None   E35D, M36I, R41K, R57K, L63T, H69K, L89MCRF01_AE
Bila (2013)MzNac197HIV-1KF927395None   I13V, K14R, G16E, K20R, E35D, M36I, R41K, R57K, L63T, I64L, H69K, L89MCRF01_AE
Chen (2013)11YNHH11011YNHH110JX412359None   M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
Chow (2013)MY3MS861MY3MS861KC478056None   M36I, L63T, H69K, L89MCRF01_AE
Frentz (2013)EHR-36580EHR-36580JX300151None  L33FI13V, Q18QH, M36I, R41K, L63T, H69K, L89MCRF01_AE
 EHR-606204EHR-606204JX300549None   I13V, K14R, I15V, M36I, N37D, R41K, K43R, L63T, I64M, H69K, L89MCRF01_AE
Hassan (2013)RS11000276RS11000276JQ698367None   T12TP, I13V, E35D, M36I, R41K, K45R, R57K, L63T, H69K, L89MCRF01_AE
Hawke (2013)1127416411274164KC237887None   L10V, I13V, G16E, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 1846856418468564KC237999None   L10LV, K14KR, I15IV, Q18E, L19LM, K20R, E35D, M36I, R41K, L63T, H69K, I72IT, L89M, I93LCRF01_AE
Kiertiburanakul (2013)R71196R71196KC921876None   L10I, I13V, G16E, E35D, M36I, L63T, H69Q, L89MCRF01_AE
 R71TS109R71TS109KC921587None   I13V, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93LCRF01_AE
 R73077R73077KC810367None   L10V, T12I, I13IV, I15V, G16E, E35D, M36I, N37ND, P39PS, R41K, R57K, L63T, H69K, L89MCRF01_AE
 R74109R74109KC791328None   L10V, I13V, G16E, E35D, M36I, R41K, L63T, E65D, H69K, K70R, L89M, I93LCRF01_AE
 R71TS178R71TS178KC921653None   T12P, I13V, G16E, E35D, M36I, P39T, D60E, L63T, H69K, L89ICRF01_AE
 R12TS034R12TS034KC994341None   L10I, I13V, G16GE, E35D, M36I, L63T, H69K, K70R, I72IT, L89MCRF01_AE
 R74157R74157KC791376None   L10V, I13V, G16E, E35D, M36I, L63T, H69K, K70R, L89MCRF01_AE
 R41002R41002KC970859None  L33FL10I, M36I, R41K, L63T, H69K, L89M, I93L, L97ICRF01_AE
 R71TS260R71TS260KC921729None   L10I, I13V, I15V, K20R, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R71TS263R71TS263KC921732None   L10I, I13V, M36I, R41K, L63T, H69K, K70R, T74A, L89M, I93LCRF01_AE
 R73028R73028KC810548None  V11IL10M, I13V, G16E, E35D, M36I, P39S, R57K, L63T, H69K, L89MCRF01_AE
 R72093R72093KC867632None   L10I, I13V, L19Q, E35D, M36I, R41K, L63T, C67Y, H69K, L89MCRF01_AE
 R72041R72041KC867586None   L10I, I13V, G16E, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R73212R73212KC810487None   L10V, T12P, I13V, E35D, M36I, R41K, K43R, L63T, H69K, L89MCRF01_AE
 R75001R75001KC962520None   I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R71223R71223KC921453None   L10V, T12P, I15V, K20R, E35D, M36I, R41K, Q61E, I62V, L63T, E65D, H69K, L89M, I93LCRF01_AE
 R71057R71057KC921803None   I13V, I15V, G16E, E35D, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
 R73127R73127KC810412None   L10LV, I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R71TS111R71TS111KC921589None   G16E, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R71127R71127KC921840None  L33FI13V, E35D, M36I, R41K, L63T, H69K, L89M, I93VCRF01_AE
 R74028R74028KC791248None   I13V, I15IV, K20R, E35D, M36I, R41K, L63T, C67Y, H69K, I72T, L89MCRF01_AE
 R73043R73043KC810334None   I13V, G16E, K20R, E35D, M36I, R41K, K43R, L63T, I64L, H69K, L89I, Q92KCRF01_AE
 R73005R73005KC810561None   L10I, I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R73100R73100KC810388None   L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63T, H69K, I72IV, L89MCRF01_AE
 R71TS169R71TS169KC921645None   I13V, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93LCRF01_AE
 R41161R41161KC970897None   L10V, I15V, G16E, K20R, E35D, M36I, R41K, L63T, H69K, I72T, L89MCRF01_AE
 R41069R41069KC970950None   I13V, I15V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R71113R71113KC921829None   L10I, I13V, G16E, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R74149R74149KC791368None   L10V, I13V, I15V, E35ED, M36I, R41K, L63T, I64V, H69KCRF01_AE
 R74182R74182KC791401None   T12TA, K14KR, I15IV, G16GE, E35D, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
 R41048R41048KC970934None   L10LI, I13V, I15V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R41008R41008KC970861None   L10I, I13V, I15V, G16E, E35D, M36V, R41K, L63T, H69K, L89M, I93LCRF01_AE
 R42024R42024KC971015None   I13V, I15V, L19I, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R74202R74202KC791420None   L10LI, I13V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, H69K, I72IV, L89MCRF01_AE
 R71158R71158KC921852None   L10I, I13V, K14R, I15V, G16E, E35D, M36I, R41K, L63T, H69K, V75G, L89MCRF01_AE
 R71TS131R71TS131KC921608None   L10I, I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 X12027X12027KC994362None   L10I, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R74192R74192KC791411None   I13V, G17E, E35D, M36I, R41K, R57K, L63T, H69K, A71V, I72IT, I93LCRF01_AE
 R72253R72253KC857074None   I13V, M36I, R41K, L63T, H69K, V82I, L89M, I93LCRF01_AE
 R72203R72203KC857024None   I13V, M36I, R41K, L63T, H69K, L89MCRF01_AE
 R72201R72201KC857022None   L10I, G16E, E35D, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
 R72239R72239KC857060None   L10V, K14R, E35D, M36I, N37D, R41K, R57KN, L63T, H69K, K70R, L89MCRF01_AE
 R72128R72128KC856958None   L10V, T12TA, I13V, K14R, G16A, M36I, R41K, L63T, H69K, L89MCRF01_AE
Kiptoo (2013)KTL018KTL018KC516994None   I13V, K14R, M36I, N37D, R41K, R57K, L63T, I64L, H69K, L89MCRF01_AE
Li (2013)28582858JQ901067None   G16E, L19I, E35D, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
Li (2013)21692169JQ302651None   G16E, E35D, M36I, R41K, L63T, H69K, K70R, I72EV, L89M, I93LCRF01_AE
 22082208JQ302678None   L10I, I13V, M36I, R41K, L63T, H69K, L89MCRF01_AE
Ong (2013)08MYKL02908MYKL029KC181256None   I13V, I15V, L19I, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 09MYKL02609MYKL026KC181225None   L5F, L10I, I13V, G16E, K20R, E35D, M36I, L63T, C67S, H69K, L89MCRF01_AE
Pircher (2013)B1159B1159JX110344None   L10I, I13V, M36I, R57K, L63T, H69K, L89MCRF01_AE
Rusine (2013)711H711HKC841735None   L10M, I13V, E35D, M36I, N37D, R41K, K45R, R57K, L63T, C67S, H69K, L89MCRF01_AE
 447H447HKC841698None   L10M, T12A, I13V, K14KR, G16E, E35D, M36I, R41K, R57K, L63T, H69K, L89MCRF01_AE
Wu (2013)BBP80BBP80KC203293None   K20R, E35D, M36I, R41K, L63T, H69K, K70R, L89M, I93LCRF01_AE
Zeng (2013)cdbc41cdbc41KC352113None   I15V, D29N, E35D, M36I, R41K, L63T, H69K, L89M, I93MCRF01_AE
 cdbc15cdbc15KC352087None   E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE