<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L63T
Rx PI-naive
IncludeMixtures No
References 37
Patients 68
Isolates 70
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Hsu (2005)BAA157668BAA157668AY870174None   L10LV, I13V, K14KR, I15V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
Ly (2005)NL_KHM_CA22KHM_CA22DQ013530None   L10I, I13V, M36I, R41K, L63T, H69K, K70RCRF01_AE
 NL_KHM_CA63KHM_CA63DQ013569None   L10I, I13V, M36I, R41K, L63T, H69K, L89LMCRF01_AE
 NL_KHM_CD11KHM_CD11DQ013641None   I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 NL_KHM_CD7KHM_CD7DQ013637None  V11IL10I, I13V, K14R, M36I, R41K, L63T, H69K, L89MCRF01_AE
Tee (2005)03MYKL135303_1353AY904531None   I15V, G16E, E35D, M36V, R41K, L63T, H69K, K70R, L89MCRF01_AE
 03MYKL135403_1354AY904532None   L10I, K20R, E35D, M36I, R41K, L63T, H69K, L89M, T91NCRF01_AE
Baker (2007)P0018P0018-240105EF186133None   I13V, K14R, I15V, E35D, M36L, N37D, R41K, L63T, H69K, V77I, L89MCRF01_AE
Church (2008)347758P347758PEU380724None   I13V, G16E, E35D, M36I, R41K, R57K, L63T, I64V, H69KCRF01_AE
Holguin (2008)SP41-58559SP41-58559EU342821None   T12S, K14R, I15V, L19V, K20R, M36I, R41K, R57K, Q61H, L63T, H69K, L89M, I93LCRF01_AE
Ntemgwa (2008)775004CA7750EU220698None   L10V, I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63T, H69K, K70R, L89MCRF01_AE
Sirivichayakul (2008)BED-49BED-49PrJQ364299None   T12P, I13V, K20R, E35D, M36I, R41K, R57K, L63T, H69K, L89MCRF01_AE
 NBC-45NBC-45PrJQ364343None   E35D, M36I, R41K, L63T, H69K, V82I, L89M, I93LCRF01_AE
Auwanit (2009)23AE-PR23FJ463516None   I13V, I15V, Q18E, E35D, M36I, R41K, R57K, L63T, H69K, L89MCRF01_AE
 95AE-PR95FJ463528None   I13IV, I15V, Q18E, E35D, M36I, R41K, R57K, Q58T, L63T, H69K, L89MCRF01_AE
 104AE-PR104FJ463530None   L10I, I13V, I15V, G16E, K20E, E35D, M36I, R41K, G51*R, L63T, H69K, K70R, L89MCRF01_AE
 130AE-PR130FJ463540None   L10I, I13V, I15V, G16E, E35D, M36I, R41K, L63T, H69K, K70R, L89MCRF01_AE
Ayouba (2009)FD0526FD0526PIGQ352076None   L10V, I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
Eshleman (2009)K20527W208-101565FJ389121None   I13V, K20T, E35D, M36I, R41K, K45R, R57K, D60E, L63T, H69K, L89MCRF01_AE
Ishizaki (2009)A2_129A2_129FJ007011None   E35D, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
 A233A233aFJ007224None   I13V, E35D, M36I, R41K, L63T, H69K, I72T, L89MCRF01_AE
Vercauteren (2009)pt18012498506932GQ399223None   I13IV, I15V, E35D, M36I, R41K, R57K, L63T, H69K, L89MCRF01_AE
Chin (2010)C182C182GQ290719None   L10I, I13V, E35D, M36I, R41K, L63T, H69K, L89M, L97ICRF01_AE
Djoko (2010)680CD0639FR666680None   I13V, K14T, G16E, E35D, M36I, P39AT, R41K, K45R, R57K, I62V, L63T, I64IV, E65D, H69R, L89MCRF01_AE
Jullaksorn (2010)CR21CR21-Jan09DGQ857396None   L10V, T12P, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
Selimova (2010)40MOSR40MOSRHM345569None   E35ED, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
Zolfo (2010)A14013A 14013 M30HM565665None   T12A, K20R, M36I, R41K, D60E, L63T, I64L, H69K, L89M, I93LCRF01_AE
 A13748A 13748 M18HM565699None   L10I, I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
  A 13748 M24HM565637None   L10I, I13V, E35D, M36I, R41K, K55KR, L63T, H69K, L89MCRF01_AE
 A14549A 14549 M18HM565713None   L10I, I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 A14109A 14109 RSHM565720None   I13V, E35D, M36I, K45R, R57K, L63T, H69K, L89M, T91VCRF01_AE
  A 14109 M18HM565627None   I13V, G16GE, E35D, M36I, K45R, R57K, L63T, H69K, L89M, T91VCRF01_AE
Avi (2011)086u086uGQ926649None   L10I, I13V, K14R, E35D, M36I, R41K, D60E, L63T, I64L, H69K, L89M, I93LCRF01_AE
Bontell (2011)Pat04508.VL772HsHQ852871None   L10I, I13V, G16E, L19LI, E35D, M36I, R41K, L63T, H69K, L89ICRF01_AE
 Pat00509.VL983UsHQ852911None   G16E, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
Dean (2011)IVVI0259IVVI0259JQ312362None   T12P, I13V, K14R, Q18H, E35D, M36I, P39S, R41K, L63T, H69K, V82VI, L89MCRF01_AE
 IVVI0337IVVI0337JQ312367None   T12P, I13V, K14R, Q18H, E35D, M36I, P39S, R41K, L63T, H69K, L89MCRF01_AE
 IVVI7396IVVI7396JQ312421None   L10V, K14R, G16E, M36I, N37D, R41K, L63T, H69K, L89M, I93LCRF01_AE
Lazaro (2011)VT-M22VT-M22HQ542650None   I13V, E35D, M36I, N37D, R41K, L63T, E65D, H69K, L89MCRF01_AE
 DT-M21DT-M21HQ542706None   T12A, I13V, E35D, M36I, R41K, K45R, L63T, H69K, V82I, L89MCRF01_AE
Ng (2011)HM069HM069HQ539098None   E35D, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
 HM149HM149HQ539174None   L10I, E35D, M36I, R41K, L63T, C67H, H69K, L89MCRF01_AE
Su (2011)GXNN7478GXNN7478HQ588273None   G16E, E35D, M36I, R41K, L63T, H69K, K70R, I72T, L89M, I93LCRF01_AE
An (2012)09LNA04109LNA041JX960618None   L19I, E35D, M36I, R41K, L63T, H69K, V82I, L89M, I93LCRF01_AE
 10LNA10510LNA105JX960626None   I13V, G16E, L19M, K20R, E35D, M36I, R41K, K45R, I62V, L63T, H69K, V82I, L89M, I93LCRF01_AE
Chen (2012)YN10DH0100YN10DH0100JQ658721None   G16E, L19M, E35D, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
Hassan (2012)RS11000276RS11000276JQ698367None   T12TP, I13V, E35D, M36I, R41K, K45R, R57K, L63T, H69K, L89MCRF01_AE
Karlsson (2012)SE_176SE_176JQ698788None   L10I, I13V, G16E, E35D, M36I, R41K, L63T, H69Q, I72V, L89MCRF01_AE
Rolland (2012)AA065a07LAA065a07LJX447424None   I13V, G16E, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 AA091a03LAA091a03LJX447738None   I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 AA113a_LH8AA113a_LH8JX448084None   T12I, I13V, G16E, E35D, M36I, R41K, L63T, H69K, K70R, I72T, L89M, T91VCRF01_AE
Ssemwanga (2012)3683HR3683HRJF800225None   I13V, I15V, E35D, M36I, R41K, R57K, D60E, L63T, H69K, L89MCRF01_AE
Tran (2012)HPA013HPA013AB690876None   L10I, I13V, G16E, E35D, M36I, R41K, L63T, H69K, I72IT, P79PS, L89MCRF01_AE
 HPA171HPA171AB690894None   L10I, I13V, G16E, E35D, M36I, R41K, I62V, L63T, H69K, L89MCRF01_AE
 HPA409HPA409AB690942None   L10LI, I13V, G16E, E35D, M36I, R41K, L63T, H69K, L89ICRF01_AE
 HPA423HPA423AB690944None   I13V, K20R, E35D, M36I, N37D, R41K, L63T, H69K, I72T, L89MCRF01_AE
Yang (2012)37693769JQ617245None   W6WL, L10LI, I13V, G16A, E35D, M36IL, N37DE, R41RK, K43KR, L63T, E65ED, H69K, K70R, I72IMT, L89MCRF01_AE
Yang (2012)GZ051GZ051JN848839None   L10I, I13V, G16E, E35D, M36I, P39PT, R41K, K45R, L63T, H69K, L89MCRF01_AE
 GZ093GZ093JN848861None   I13V, M36I, R41K, R57K, L63T, H69R, L89MCRF01_AE
 GZ109GZ109JN848866None   E35D, M36I, R41K, R57K, L63T, H69R, L89M, I93LCRF01_AE
 GZ134GZ134JN848875None   I13V, E35D, M36I, R41K, R57K, L63T, H69K, I72IT, L89MCRF01_AE
 GZ096GZ096JN848891None   I13V, E35D, M36I, R41K, K45R, R57K, L63T, G68GE, H69KR, L89MCRF01_AE
 GZ108GZ108JN848893None   E35D, M36I, R41K, R57K, L63T, H69R, L89M, I93LCRF01_AE
 GZ252GZ252JN848918None   I13V, G16E, L19I, K20R, E35D, M36I, R41K, L63T, H69K, K70R, L89MCRF01_AE
Chen (2013)11YNHH11011YNHH110JX412359None   M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE
Frentz (2013)EHR-36580EHR-36580JX300151None  L33FI13V, Q18QH, M36I, R41K, L63T, H69K, L89MCRF01_AE
 EHR-606204EHR-606204JX300549None   I13V, K14R, I15V, M36I, N37D, R41K, K43R, L63T, I64M, H69K, L89MCRF01_AE
Hawke (2013)1127416411274164KC237887None   L10V, I13V, G16E, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 1846856418468564KC237999None   L10LV, K14KR, I15IV, Q18E, L19LM, K20R, E35D, M36I, R41K, L63T, H69K, I72IT, L89M, I93LCRF01_AE
Li (2013)28582858JQ901067None   G16E, L19I, E35D, M36I, R41K, L63T, H69K, L89M, I93LCRF01_AE

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