<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L63T
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 28
Isolates 30
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Ariyoshi (2003)JPN19JPN19A NFV59N88SL10FG16E, K20IT, E35D, M36I, R41K, L63T, I64V, H69K, L89M, I93LCRF01_AE
  JPN19BAY900861NFV77N88SL10FG16E, K20I, E35D, M36I, R41K, L63T, I64V, H69K, L89M, I93LCRF01_AE
Nukoolkarn (2004)7474 RTV I54V, V82AL33F, N83DL10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89MCRF01_AE
 267267 RTV, IDV M46I L63T, I72T, L89MCRF01_AE
Chantratita (2005)14-014814-0148DQ130513PINAM46I, I54A, V82A L10I, I13V, G16E, K20I, E35D, M36I, R41K, L63T, I64L, H69K, L89MCRF01_AE
 G558G558DQ130132PINAI54V, V82AL33F, N83DL10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89MCRF01_AE
 G577G577DQ130142PINA  L10I, I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 G586G586DQ130150PINAV82AQ58EW6R, L10I, I13V, G16E, K20I, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 G587G587DQ130151PINA  L10I, I13V, E35D, M36I, R41K, L63T, I64V, E65D, H69KCRF01_AE
 G614G614DQ130166PINAM46I, I54A, V82A L10I, I13V, G16E, K20I, E35D, M36I, R41K, L63T, I64L, H69K, T74S, L89MCRF01_AE
 G625G625DQ130174PINA  I13V, G17E, E34A, E35D, M36I, R41K, Q61H, L63T, H69K, K70R, I72T, T74A, L89MCRF01_AE
 G641G641DQ130184PINA  E35D, M36I, L63T, H69K, I72T, L89MCRF01_AE
 G727G727DQ130223PINA  K20R, E35D, M36I, R41K, L63T, H69K, V82I, L89M, I93LCRF01_AE
 NP230NP230DQ130315PINA  L10I, I13V, E35D, M36I, R41K, L63T, H69K, P79A, L89MCRF01_AE
 NP265NP265DQ130347PINA  W6R, L10I, I13V, G17E, E35D, M36I, L63T, H69K, K70R, L89MCRF01_AE
 NP307NP307DQ130387PINA  I13V, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 NP313NP313DQ130391PINA  L10V, I13V, K14N, G16E, K20R, E35D, M36I, R41K, K43R, L63T, H69K, K70R, L89MCRF01_AE
Hsu (2005)BAA161433BAA161433AY870233IDV, SQV, RTV270G48V, L90ML33F, N83DL10I, I13V, E35D, M36I, R41K, L63T, H69K, L89IMCRF01_AE
Non-B Workgroup (2005)IL276IL276 IDV81  L10I, E35D, M36I, R41K, R57K, L63T, H69R, L89M, I93LCRF01_AE
Rosen-Zvi (2008)3606p36-2 LPV155  L10V, T12I, I13A, I15V, G16E, E35D, M36I, R41K, K45R, L63T, H69K, L89MCRF01_AE
  06p36-3 LPV155  L10V, T12I, I13AV, I15IV, G16E, E35D, M36I, R41K, K45R, L63T, H69K, I72IV, L89MCRF01_AE
Charpentier (2011)51CP0012273 Unknown, LPVNA  T12P, I13V, G16E, K20R, E35D, M36I, R41K, K55K*, L63T, E65EG, G68GE, H69KR, L89MCRF01_AE
Charpentier (2011)CR-50CR-50FJ688256PINAM46IL10FK20I, E35D, M36I, N37D, R41K, I62IV, L63T, H69K, T74A, V77VI, I85IV, L89M, I93LCRF01_AE
Nerrienet (2014)T0905041T0905041JN675801LPV   L10IV, I13V, G16E, E35D, M36I, R41K, L63T, H69K, K70R, L89MCRF01_AE
 T0929127T0929127JN675760LPV I54V, V82AL10FT12P, I13V, G16E, K20R, E35D, M36I, R41K, K45I, L63T, H69K, L89MCRF01_AE
 T0807129T0807129JN675757LPV M46I, I47V, L76V, V82FQ58EL10I, I13V, G16E, K20I, E35DN, M36I, N37ND, K55R, L63T, I64V, H69K, I72T, L89MCRF01_AE
 T0622115T0622115JN675800LPV   L10LI, I13V, G16E, E35D, M36I, R41K, I62IV, L63T, E65ED, H69K, T74S, L89MCRF01_AE
 U0519246U0519246JN675768LPV V82A L10I, I13V, G16E, K20R, E35D, M36I, R41K, L63T, H69K, T74A, L89M, I93VCRF01_AE
Jenabian (2015)DR46DR46KF735849PINA  L10V, K14R, I15IV, G16GE, L19I, E35X, M36I, N37D, R41RK, K45R, R57RK, L63T, H69K, K70KR, L89XCRF01_AE
Zain (2015)MYHIVDR303MYHIVDR303KT281500PINA  I13V, E35D, M36I, R41K, L63T, H69K, I72V, L89MCRF01_AE