<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L63S
Rx PI-naive
IncludeMixtures No
References 46
Patients 89
Isolates 95
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Lan (2003)NTHvr8NTHvr8AY238160None   I13V, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Tovanabutra (2004)01THOUR786I01_786IAY358036None   E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Hsu (2005)LYH_AY870218BAA161407AY870218None  L33FI13V, G16E, E35D, M36I, R41K, L63S, H69K, K70R, L89I, I93LCRF01_AE
 BAA157676BAA157676AY870181None   L10I, I13V, E35D, M36I, N37D, R41K, L63S, H69K, K70R, L89MCRF01_AE
Ly (2005)NL_KHM_CA54KHM_CA54DQ013560None   K20R, E35D, M36I, N37D, I62V, L63S, H69K, L89MCRF01_AE
 NL_KHM_CD12KHM_CD12DQ013642None   L10I, I13V, E35D, M36I, R41K, R57K, L63S, H69K, L89MCRF01_AE
 NL_KHM_SOS23KHM_SOS23DQ013630None   I13V, E35D, M36I, R41K, K45R, L63S, H69K, L89MCRF01_AE
Non-B Workgroup (2005)TH_189TH_189AY605594None   I13V, I15V, E35D, M36I, R41K, L63S, H69K, V82I, L89MCRF01_AE
Tee (2005)04MYKLLSW395004LSW3950AY904607None   T12A, I13V, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
 03MYKL133603_1336AY904521None   L10I, I13V, T26S, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Marechal (2006)JF_147JF_147DQ443716None   E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Tee (2006)MYKL165904MYKL1659AY960949None   E35D, M36I, R41K, I62V, L63S, H69K, L89MCRF01_AE
Watanaveeradej (2006)01TH_C257001_C2570AY945719None   I13V, E35D, M36I, N37S, R41K, L63S, H69K, L89MCRF01_AE
Gatanaga (2007)C03-2067701-1C03-2067701-1AB640465None   I13V, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
 C04-2066206-1C04-2066206-1AB640482None   I13V, E34K, M36I, R41K, L63S, H69K, V82I, L89MCRF01_AE
Holguin (2007)582659582659EF583193None   L10IV, I13V, G16E, E35D, M36I, R41K, K45R, L63S, H69K, K70R, L89MCRF01_AE
Zhong (2007)D001005CN_010EF199557None   Q2H, E35D, M36I, R41K, L63S, I64M, H69K, L89M, I93LCRF01_AE
 D002705CN_027EF199569None   M36I, R41K, L63S, H69K, K70R, L89M, I93LCRF01_AE
 D006105CN_061EF199592None   K20R, E35D, M36I, R41K, L63S, H69K, K70R, V82I, L89M, I93LCRF01_AE
 D008805CN_088EF199616None   K20R, E35D, M36I, R41K, L63S, H69K, K70R, V82I, L89M, I93LCRF01_AE
Chang (2008)TW11250TW11250EU164923None   I13V, E35D, M36I, R41K, Q58QR, L63S, H69K, K70R, L89ICRF01_AE
 TW10012aTW10012a None   I13V, E35D, M36I, R41K, L63S, H69K, K70R, L89ICRF01_AE
Ibe (2008)527527AB356463None   I13V, K14KR, I15IL, K20I, M36I, R41K, L63S, H69K, V82VI, L89M, T91VCRF01_AE
Nguyen (2008)040VN040 None   I15IV, G16E, E35D, M36I, R41K, L63S, H69K, V82I, L89M, F99XCRF01_AE
Rosen-Zvi (2008)8307p83-2 None   L10V, I13V, G16E, E35D, M36I, N37D, R41K, L63S, H69K, K70R, L89MCRF01_AE
  08p83-3 None   L10V, I13V, E35D, M36I, N37D, R41K, L63S, H69K, K70R, L89MCRF01_AE
Sirivichayakul (2008)BED-16BED-16PrJQ364273None   L10V, I13V, G16E, E35D, M36I, L63S, H69K, L89MCRF01_AE
 BED-32BED-32PrJQ364284None   G16E, E35N, M36I, R41K, L63S, H69K, I72V, I93LCRF01_AE
 BED-36BED-36PrJQ364288None   G16E, E35N, M36V, R41K, L63S, H69K, L89M, I93LCRF01_AE
 BED-37BED-37PrJQ364289None   I13V, K20I, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
 NBC-30NBC-30PrJQ364330None   G16E, K20R, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
 NBC-33NBC-33PrJQ364333None   L10V, I13V, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Aghokeng (2009)HG_0344HG_0344GU191660None   I13V, G17E, E35D, M36I, R41K, I62IV, L63S, H69K, L89MCRF01_AE
Auwanit (2009)107AE-PR107FJ463532None   L10V, I13V, M36I, R41K, L63S, H69K, L89MCRF01_AE
 159AE-PR159FJ463547None   L10I, T12A, K14KR, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Ayouba (2009)FD0704FD0704PIGQ352093None   L10I, I13V, G16GE, K20KR, E35D, M36I, R41K, K45R, L63S, H69K, K70R, V82VI, L89M, I93VCRF01_AE
 FD0901FD0901PIGQ352099None   I13V, E35D, M36I, R41K, K45R, L63S, H69K, L89MCRF01_AE
Ishizaki (2009)A225A225tFJ007219None   L10I, I13V, G16E, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
 A258A258cagFJ007239None   I13V, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Nouhin (2009)KC19KC19PROTFJ531956None   L5LF, M36I, R41K, L63S, H69K, L89MCRF01_AE
 KC25KC25PROTFJ531962None   L10I, I13V, M36I, R41K, L63S, H69K, K70R, I72V, L89MCRF01_AE
 KC34KC34PROTFJ531970None   I13V, K20R, M36I, R41K, L63S, H69K, I72V, L89MCRF01_AE
Carr (2010)0096MA01CM.0096MAGU201497None   I13V, G17E, K20I, E34K, M36I, P39S, R57K, Q61N, I62L, L63S, C67E, H69K, V77I, L89MCRF01_AE
Jullaksorn (2010)CR15CR15-Oct08RGQ857357None   I13V, E35D, M36I, G40R, R41K, L63S, H69K, L89MCRF01_AE
 CR16CR16-Apr08RGQ857294None   I13V, M36I, R41K, L63S, H69K, L89MCRF01_AE
  CR16-Jul08RGQ857327None   I13V, M36I, R41K, L63S, H69K, L89MCRF01_AE
  CR16-Oct08RGQ857358None   I13V, M36I, R41K, L63S, H69K, L89MCRF01_AE
  CR16-Jan09RGQ857391None   I13V, M36I, R41K, L63S, H69K, L89MCRF01_AE
  CR16-Apr09DGQ857422None   I13V, M36I, R41K, L63S, H69K, L89MCRF01_AE
Mosha (2010)S11PolS11PolJQ071459None   I13V, K20R, E35D, M36I, R41K, K45R, R57K, L63S, H69K, L89MCRF01_AE
Phan (2010)O911O911AB519482None   T12A, I13V, G16E, K20I, E35D, M36I, R41K, L63S, H69K, L89M, T91ACRF01_AE
 O925O925AB519496None   L10I, T12A, I13V, G16E, K20R, E35D, M36I, R41K, I62V, L63S, H69K, L89MCRF01_AE
 O927O927AB519498None   I13V, M36I, R41K, I62V, L63S, H69K, V82I, L89MCRF01_AE
 NB38NB38AB519546None   T12P, K14R, G16E, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
 AH24AH24AB519574None   I13V, E35D, M36I, R41K, R57K, L63S, H69K, L89MCRF01_AE
 AH25AH25AB519575None   I13V, E35D, M36I, R41K, R57K, L63S, H69K, L89MCRF01_AE
 AH47AH47AB519593None   G16A, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Zolfo (2010)A15056A 15056 M12HM565684None   L10V, I13V, G16E, K20R, M36I, R41K, L63S, H69KCRF01_AE
 A14435A 14435 M12HM565649None   L10I, I13V, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
  A 14435 M18HM565648None   L10I, I13V, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Bontell (2011)Pat05108.VL765HsHQ852865None   T12P, K14R, G16E, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Dean (2011)IVVI2001IVVI2001JQ312381None   L10LI, I13V, I15IV, E35ED, M36I, R41K, L63S, H69K, L89MCRF01_AE
Hamers (2011)CP076301774CP076301774HQ993760None   I13V, G16E, K20R, E35D, M36I, R41K, K45KR, R57K, L63S, H69K, I72T, L89MCRF01_AE
Ndembi (2011)AICPS730AICPS730HQ702644None   I13V, I15V, K20R, E35D, M36I, R41K, K45R, R57K, L63S, H69K, L89MCRF01_AE
Ng (2011)FREE065FREE065HQ539030None  L33FI13V, G16E, N37S, P39S, L63S, H69K, K70R, L89M, I93LCRF01_AE
 HM012HM012HQ539047None   L10I, I13V, G16E, E35D, M36I, R57K, L63S, H69K, L89MCRF01_AE
 HM036HM036HQ539069None   I13V, I15V, G16E, E35D, M36I, R57K, Q61E, I62V, L63S, H69K, K70R, L89MCRF01_AE
 HM119HM119HQ539144None   I13V, I15V, G16E, K20R, E35D, M36I, R57K, D60E, L63S, H69K, L89M, I93LCRF01_AE
 HM140HM140HQ539165None   T12P, I13V, K14R, E35D, M36I, R41K, L63S, H69K, T74S, L89MCRF01_AE
 MOVL224MOVL224HQ539203None   I13V, I15V, G16E, K20R, E35D, M36I, R57K, D60E, L63S, H69K, L89M, I93LCRF01_AE
Ngo-Giang-Huong (2011)PHPT4771PHPT4771PR-RTHQ996521None   L10N, K20KR, M36I, R41K, L63S, H69K, L89MCRF01_AE
 PHPT0650PHPT0650PR-RTHQ996527None   I13V, E35D, M36I, R41K, R57K, L63S, H69K, K70R, L89MCRF01_AE
Su (2011)GXNN0143GXNN0143HQ588301None   T12P, G16E, E35D, M36I, R41K, L63S, H69K, L89M, I93LCRF01_AE
Zeng (2011)U11U11JF505619None   T12A, E35D, M36I, R41K, L63S, H69K, K70R, L89MCRF01_AE
An (2012)10LNA29410LNA294JX960619None   T12S, L19I, K20R, E35D, M36I, R41K, L63S, H69K, V82I, L89M, I93LCRF01_AE
 10LNA91810LNA918JX960620None   T12S, L19I, K20R, E35D, M36I, R41K, L63S, H69K, V82I, L89M, I93LCRF01_AE
 09LNA42509LNA425JX960621None   T12S, L19I, E35D, M36I, R41K, L63S, H69K, V82I, L89M, I93LCRF01_AE
De Gascun (2012)IRL35854IRL35854JN622222None   L10V, I13V, I15V, K20R, M36I, N37ND, R41RK, L63S, H69K, K70R, L89MCRF01_AE
 IRL39248IRL39248JN622223None   L10V, I13V, K20R, M36I, R41K, L63S, H69K, K70R, L89MCRF01_AE
Kijak (2012)04TH32853104TH328531JN248324None   G16E, K20R, E35D, M36I, R41K, L63S, H69K, L89M, I93LCRF01_AE
 05TH84174905TH841749JN248356None   I13V, E35D, M36I, R41K, K43R, L63S, H69K, L89M, I93TCRF01_AE
Rolland (2012)AA007a_WG14AA007a_WG14JX446760None   L10I, T12A, I13V, K14R, G16E, E35D, M36I, R41K, I62V, L63S, H69K, L89MCRF01_AE
 AA044a_LH20AA044a_LH20JX447218None   I13V, E35D, M36I, R41K, L63S, H69KCRF01_AE
 AA051b03LAA051b03LJX447291None   L10I, I13V, K14R, E35D, M36I, R41K, K43R, I62V, L63S, H69K, V82I, L89MCRF01_AE
 AA057a07LAA057a07LJX447325None   I13V, I15V, E35D, M36I, R41K, Q61E, L63S, H69K, K70R, L89MCRF01_AE
 AA090a_WG5AA090a_WG5JX447731None   I13V, K20R, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
 AA097a01LAA097a01LJX447848None   T12P, I13V, D25DG, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Ssemwanga (2012)4668HR4668HRJF800202None   I13V, E35D, M36I, R41K, K45R, R57K, L63S, H69K, K70R, L89MCRF01_AE
Telan (2012)1111795211117952AB747464None  L10FK20R, E35D, M36I, R41K, Q61D, L63S, C67S, H69K, I72T, L89M, I93LCRF01_AE
 1109624511096245AB747493None   K20R, M36I, P39S, R41K, K45R, L63S, H69K, L89M, I93LCRF01_AE
Tran (2012)HPV2_203HPV2_203AB690976None   I13V, M36I, R41K, L63S, H69K, L89MCRF01_AE
Yang (2012)KN-15KN-15JQ616929None   T12S, I13V, E35D, M36I, R41K, K45R, R57K, L63S, H69K, L89MCRF01_AE
Youngpairoj (2012)cm161bbcm161bbDQ166434None   I13V, K20R, E35N, M36I, N37D, R41K, L63S, H69K, L89MCRF01_AE
Frentz (2013)EHR-19532EHR-19532JX299867None   L10I, I13V, E35D, M36I, R41K, K45R, R57K, L63S, H69K, L89MCRF01_AE
Hawke (2013)2103286621032866KC238058None   I13V, G16E, E35D, M36I, R41K, K45R, R57K, L63S, H69K, L89MCRF01_AE

Database

Resources

Team