<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L63H
Rx PI-naive
IncludeMixtures No
References 23
Patients 44
Isolates 45
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Sirivichayakul (2001)SS045098045098AF187037None   L10I, I13V, G16E, E35D, M36I, R41K, L63H, H69K, L89M, I93VCRF01_AE
Ly (2005)NL_KHM_POP5KHM_POP5DQ013605None   T12P, I13V, G16GE, E35D, M36I, R41K, L63H, H69K, K70Q, L89ICRF01_AE
Non-B Workgroup (2005)TK3012TK3012 None   E35D, M36I, R41K, I62V, L63H, H69K, L89MCRF01_AE
Auwanit (2009)25AE-PR25FJ463517None   E35D, M36I, R41K, I62V, L63H, H69K, L89MCRF01_AE
Koyalta (2009)19TCHAD-19FJ688178None   I13V, G16E, L19I, E35N, M36I, N37D, R41K, K45R, R57K, L63H, H69K, I72V, V75I, L89MCRF01_AE
Bontell (2011)Pat06208.VL731HsHQ852854None   I13V, K20R, M36I, N37D, R41K, L63H, H69K, K70R, L89M, I93LCRF01_AE
 Pat05408.VL762HiHQ852862None   L10I, I13V, G16E, M36I, R41K, L63H, H69K, L89M, I93IL, L97ICRF01_AE
Kao (2011)Pat05036627HQ657990None   L10V, I13V, G16E, M36I, R41K, K45R, L63H, H69K, K70R, L89M, I93LCRF01_AE
Lazaro (2011)DN-M4DN-M4HQ542657None   G16E, E35D, M36I, R41K, I62V, L63H, H69K, L89MCRF01_AE
De Gascun (2012)IRL52172IRL52172JN622231None   L10IV, I13V, E35D, M36I, R41K, R57RK, I62V, L63H, H69K, P79PS, L89MCRF01_AE
Karlsson (2012)SE_140SE_140JQ698765None   I13V, G16E, E35D, M36I, R41K, R57K, L63H, E65EK, H69K, R87RQ, L89M, T96TICRF01_AE
Nazziwa (2012)51191015119101JX499006None   I13V, K14R, E35D, M36I, R41K, R57K, I62V, L63H, H69K, V82I, L89MCRF01_AE
Zeng (2012)CN0892CN0892JQ028212None   T12P, I13V, E35D, M36I, R41K, L63H, H69K, L89MCRF01_AE
Chow (2013)10MYKJ02510MYKJ025KC477957None   T12I, G16E, E35D, M36I, R41K, K45KR, L63H, H69K, L89M, I93LCRF01_AE
Kiertiburanakul (2013)R73074R73074KC810364None   I15IV, G16E, E35D, M36I, R41K, I62V, L63H, H69K, L89MCRF01_AE
 R71TS032R71TS032KC921512None   I13V, E35D, M36I, R41K, R57K, L63H, H69KCRF01_AE
 R73047R73047KC810338None   L10LI, I13V, K20KI, E35D, M36I, R41RK, I62V, L63H, H69K, P79PA, V82I, L89MCRF01_AE
 R71TS194R71TS194KC921667None   I13V, E35D, M36I, R41K, R57K, L63H, H69K, L89MCRF01_AE
 R71TS292R71TS292KC921759None   I13V, K14R, G16E, E35D, M36I, R41K, L63H, H69K, L89M, I93LCRF01_AE
 R71078R71078KC921815None   I13V, E35D, M36I, R41K, R57K, L63H, H69K, L89MCRF01_AE
 R71099R71099KC921821None   I13V, G16E, E35D, M36I, R41K, L63H, H69K, L89MCRF01_AE
 R74040R74040KC791260None   I13V, E35D, M36I, R41K, I62V, L63H, H69K, L89MCRF01_AE
 R73240R73240KC810514None   I13V, G16E, K20KR, E35D, M36I, R41K, L63H, H69K, L89I, I93LCRF01_AE
 R74183R74183KC791402None   L10V, I13V, G16E, K20R, E35D, M36I, P39PS, R41K, R57K, I62V, L63H, H69K, K70R, I72V, T74S, L89MCRF01_AE
 R71TS040R71TS040KC921519None   L10V, I13V, E35D, M36I, R41K, D60E, Q61E, I62V, L63H, H69K, L89MCRF01_AE
 R72163R72163KC856991None   I13V, G16E, E35D, M36I, R41K, I62V, L63H, H69K, L89MCRF01_AE
Li (2013)21612161JQ302645None   I13V, M36I, R41K, L63H, H69K, L89MCRF01_AE
Rusine (2013)468H468HKC841710None   L10V, I13V, G16E, E35D, M36I, R41K, R57K, L63H, E65ED, H69K, K70KR, L89MCRF01_AE
  468HKC841711None   L10V, I13V, G16E, K20KI, E35D, M36I, R41K, R57K, L63H, E65ED, H69K, K70KR, L89MCRF01_AE
Lee (2014)MBA1420MBA1420KJ907105None   T12A, I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63H, H69K, L89MCRF01_AE
Zhou (2014)10mLDTD01310mLDTD013KC913863None   I13V, G16E, K20R, E35D, M36I, R41K, L63H, H69K, K70R, L89MCRF01_AE
 09mLDTD01609mLDTD016KC913829None   I13V, I15V, E35D, M36I, R41K, L63H, H69K, L89MCRF01_AE
Budambula (2015)MK83MK83KP792077None   I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63H, H69K, L89MCRF01_AE
Li (2015)SF131887SF131887KR188135None   I15V, E35D, M36I, R41K, R57K, L63H, H69K, L89M, I93ILCRF01_AE
 SF121184SF121184KR187834None   E35D, M36I, R41K, R57K, L63H, H69K, L89M, I93LCRF01_AE
 SF111284SF111284KR187668None   E35D, M36I, R41K, R57K, L63H, H69K, L89M, I93LCRF01_AE
Meini (2015)109264109264KM438247None   L10I, I13V, G16E, E35D, M36I, R41K, R57K, L63H, H69Q, K70R, L89MCRF01_AE
Wang (2015)0625306253KM395742None   I13V, K20I, E35D, M36I, R41K, Q61H, L63H, H69K, L89M, Q92H, N98HCRF01_AE
Van Tran (2016)VI-248VI-248LC101101None   I13V, I15V, L19Q, K20R, M36I, L63H, H69K, V82I, L89M, I93LCRF01_AE
 VI-101VI-101LC100968None   I13V, G16E, K20R, E35D, M36I, N37D, R41K, L63H, H69K, K70R, I72T, L89M, I93LCRF01_AE
 VI-066VI-066LC100942None   E35D, M36I, R41K, L63H, I66T, H69K, L89M, I93LCRF01_AE
 VI-040VI-040LC101193None   I15V, K20R, E35D, M36I, R41K, Q61E, L63H, H69K, L89M, I93LCRF01_AE
 VI-083VI-083LC100953None   L10V, T12TP, K14KR, G16E, Q18QE, M36I, R41K, L63H, H69K, I72V, L89M, I93LCRF01_AE
 VI-057VI-057LC100937None   T12P, E35D, M36I, R41K, L63H, H69K, L89M, I93LCRF01_AE
 VI-172VI-172LC101036None   T12P, I13V, E35D, M36I, R41K, R57K, L63H, H69K, K70R, L89MCRF01_AE