<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L63A
Rx PI-naive
IncludeMixtures No
References 26
Patients 59
Isolates 61
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Lan (2003)NTHvr98NTHvr98AY238310None   G16E, E35D, M36I, R41K, L63A, H69K, L89M, I93LCRF01_AE
Hsu (2005)LYH_AY870194BAA161378AY870194None   I13V, E35D, M36I, R41K, R57K, L63A, H69K, L89MCRF01_AE
Ly (2005)NL_KHM_SOS21KHM_SOS21DQ013628None   I13V, E35D, M36I, R41K, R57K, L63A, H69K, L89MCRF01_AE
Gatanaga (2007)C03-51110014-1C03-51110014-1AB640114None   I13V, M36I, R41K, L63A, H69K, L89MCRF01_AE
 C03-51110063-1C03-51110063-1AB640163None   L10I, I13V, G16A, E35D, M36I, R41K, L63A, H69K, L89M, I93VCRF01_AE
Vercauteren (2009)pt48XKy3Xx0wv4GQ400976None   L10LI, T12A, I13V, K14KR, G16E, E35D, M36I, R41K, L63A, H69K, L89M, C95CGCRF01_AE
Hattori (2010)C06-504608C06-504608AB864595None   I13V, L33V, E35D, M36I, R41K, R57K, L63A, H69K, L89MCRF01_AE
 C07-51110553C07-51110553AB864960None   I13V, E35D, M36I, R41K, L63A, H69K, K70R, L89MCRF01_AE
 C08-504604C08-504604AB864610None   L10I, I13V, E35D, M36I, R41K, L63A, H69K, K70R, L89MCRF01_AE
Zolfo (2010)A14708A 14708 M12HM565645None   I13V, E35D, M36I, R41K, K45R, L63A, H69K, L89M, N98NDCRF01_AE
  A 14708 M18HM565644None   I13V, E35D, M36I, R41K, K45R, L63A, H69K, L89MCRF01_AE
 A14091A 14091 RSHM565725None   I13IV, E35ED, M36I, R41K, L63A, H69K, L89LM, I93ILCRF01_AE
  A 14091 M18HM565628None   I13IV, E35ED, M36I, R41K, L63A, H69K, L89LM, I93ILCRF01_AE
Ng (2011)HM072HM072HQ539101None   I15V, G16E, E35D, M36I, R57K, L63A, H69K, K70R, L89MCRF01_AE
 HM098HM098HQ539124None   K14R, E35D, M36I, R41K, L63A, H69K, K70RCRF01_AE
Ngo-Giang-Huong (2011)PHPT2601PHPT2601PR-RTHQ996519None   K20R, E35D, M36I, N37D, R57K, L63A, H69K, L89MCRF01_AE
Karlsson (2012)SE_111SE_111JQ698744None   K14R, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
Rolland (2012)AA101a_WG1AA101a_WG1JX447936None   I13V, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
Ssemwanga (2012)RCC_TDR_480069RCC_TDR_480069JQ266046None   L10V, I13V, K14R, E35D, M36I, R41K, R57K, L63A, H69K, L89MCRF01_AE
Ssemwanga (2012)3445HR3445HRJF800199None   I13V, K14R, E35D, M36I, R41K, R57K, Q61N, L63A, H69K, L89MCRF01_AE
Yang (2012)37613761JQ617237None   W6WL, M36I, R41K, L63A, H69K, I93LCRF01_AE
Yang (2012)GZ023GZ023JN848849None   I13V, G16E, E35D, M36I, R41K, K43KR, L63A, H69K, I72V, V77I, L89MCRF01_AE
Zeng (2012)CN1291CN1291JQ028249None   G16E, E35D, M36I, R41K, L63A, H69K, L89M, I93LCRF01_AE
 CN0312CN0312JQ028408None   I13V, E35D, M36I, R41K, L63A, H69R, L89M, I93LCRF01_AE
 CN0317CN0317JQ028409None   L10P, I13V, I15V, G16E, E35D, M36I, R41K, L63A, H69K, L89M, I93LCRF01_AE
Antoniadou (2013)GR027GR027KF671762None   I13V, E35D, M36I, R41K, K45R, R57K, L63A, H69K, I72IV, L89MCRF01_AE
 GR060GR060KF671782None   I13V, E35D, M36I, R41IK, K45R, R57K, L63A, H69K, L89MCRF01_AE
Avidor (2013)19281928KC184265None   G16E, K20R, E35D, M36I, R41K, L63A, I64IM, H69K, L89M, I93LCRF01_AE
Billong (2013)MR078MR078KF192231None   L10IV, I13V, L19I, E35N, M36I, N37D, R41K, K43R, L63A, H69K, L89MCRF01_AE
Frentz (2013)EHR-25662EHR-25662JX299986None   I13V, K20R, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
 EHR-65936EHR-65936JX300650None   I13V, K20R, E35D, M36I, N37D, R41K, K43KR, L63A, H69KQ, K70KR, L89MCRF01_AE
 EHR-68446EHR-68446JX300693None   I13V, K20R, E35D, M36I, R41K, R57K, L63A, H69K, L89MCRF01_AE
 EHR-79765EHR-79765JX300902None  L10LFL19Q, E35D, M36I, R41K, L63A, H69K, V82VI, L89MCRF01_AE
 EHR-86400EHR-86400JX301004None   K14R, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
 EHR-89381EHR-89381JX301056None   K20R, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
Kiertiburanakul (2013)R71047R71047KC921800None   L10V, T12A, I13V, G16E, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
 R72071R72071KC867611None   I13V, E35D, M36I, N37D, R41K, K55R, L63A, H69K, L89MCRF01_AE
 R71TS054R71TS054KC921533None   L10V, I13V, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
 R72101R72101KC867638None   I13V, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
 R71117R71117KC921833None   L10V, I13V, Q18H, E35D, M36I, R41K, L63A, H69K, L89ICRF01_AE
 R71077R71077KC921814None   L10V, T12A, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
 R71101R71101KC921823None   I13V, G16E, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
 R71179R71179KC921862None   I13V, E35D, M36I, R41K, R57K, L63A, H69K, L89MCRF01_AE
 R74097R74097KC791316None   E35D, M36I, R41K, L63A, H69KCRF01_AE
 R74017R74017KC791237None   T12A, L19I, E35D, M36I, R41K, D60E, Q61E, L63A, H69K, L89MCRF01_AE
 R75007R75007KC962524None   I13V, I15V, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
 R73147R73147KC810429None   L10V, I13V, K14KR, I15V, E35D, M36I, R41K, L63A, H69K, P79D, L89MCRF01_AE
 R71TS074R71TS074KC921553None   I13V, K20R, M36I, R41K, L63A, H69K, L89M, I93LCRF01_AE
 R73189R73189KC810465None   I13V, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
 R73045R73045KC810336None   I13V, E35D, M36I, R41K, R57RK, L63A, H69K, V77I, G78R, L89MCRF01_AE
 R73118R73118KC810404None   I13V, E35D, M36I, R41K, K43KR, L63A, H69K, L89MCRF01_AE
 R73253R73253KC810526None   I13V, E35D, M36I, R57K, L63A, H69K, L89MCRF01_AE
 R72109R72109KC867645None   I13V, E35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
 R72142R72142KC856971None   L10I, I13V, E35D, M36I, R41K, L63A, H69Q, L89M, I93ILCRF01_AE
 R72251R72251KC857072None   G16A, E35D, M36I, L63A, H69K, L89M, I93LCRF01_AE
Kiptoo (2013)SNH075SNH075KC516982None   E35D, M36I, R41K, R57K, I62IV, L63A, H69K, L89MCRF01_AE
Li (2013)22182218JQ302686None  L10LFE35D, M36I, R41K, L63A, H69K, L89MCRF01_AE
Pircher (2013)B1149B1149JX110335None   L10I, I13V, E35D, M36I, R41K, K45R, R57K, L63A, C67E, H69K, L89MCRF01_AE
 B1139B1139JX110326None   L10I, I13IV, K14KR, G16GE, E35DN, M36I, R41K, K45R, R57K, L63A, C67E, H69K, K70KR, L89MCRF01_AE
Rusine (2013)704H704HKC841729None   T12S, I13IV, L19I, E35D, M36I, R41K, R57K, L63A, H69K, L89MCRF01_AE
Wu (2013)HBP130HBP130KC203321None   A22AV, L23LF, T31TP, E35D, M36IV, R41K, L63A, H69K, V82VI, L89MCRF01_AE