<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation I54V
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 47
Isolates 48
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Chantratita (2002)G72G72AF240395PINAG48M, I54V, V82A L10I, I13V, K20I, E35D, M36I, R41K, H69K, L89ICRF01_AE
 G70G70AF240394PINAG48V, I54V, V82AF53LL10I, I13V, K20I, E35D, M36I, R41K, H69K, T74S, L89ICRF01_AE
 G67G67AF240392PINAI54V, V82F, L90M L10I, I13V, K20I, E35N, M36I, R41K, L63P, H69K, T74S, L89M, I93MCRF01_AE
 G66G66AF240391PINAI54V, V82F, L90M L10I, I13V, K20I, E35N, M36I, R41K, L63P, H69K, T74S, L89M, I93MCRF01_AE
 G63G63AF240388PINAG48V, I54V, V82A L10I, I13V, A22V, E35D, M36I, R41K, I62V, L63P, H69K, L89ICRF01_AE
 G54G54AF240381PINAI54VL89VI13V, K20I, E35D, M36I, R41K, H69KCRF01_AE
Ariyoshi (2003)JPN42JPN42A SQV104I54V, V82F, L90ML33F, I84LL10V, I13V, I15IV, G16E, K20I, E35D, M36I, N37ND, R41K, H69K, T74S, L89I, Q92KCRF01_AE
 JPN15JPN15AY900698NFV, IDV113I54V, L90ML10F, L33II13V, K20R, E35D, M36I, R41K, I64V, H69K, L89MCRF01_AE
 JPN38JPN38 IDV, NFV129I54V, V82F L10I, I13V, G16E, K20I, E35D, M36I, R41K, K45V, L63LH, H69K, K70R, L89M, F99FLCRF01_AE
 JPN41JPN41A IDV, SQV, NFV125G48ST, I54V, V82F, L90M L10I, I13V, G16E, K20I, E35D, M36I, P39Q, R41K, K45V, I62V, L63P, H69K, L89MCRF01_AE
  JPN41BAY900873IDV, SQV, NFV, APV195I54V, V82F, L90LM L10I, I13V, G16E, K20I, E35DN, M36I, P39Q, R41K, K45V, G48X, I62V, L63P, H69K, L89MCRF01_AE
Montes (2004)MB_patBRI01_BRI705AJ577746SQV, NFV, RTV, LPV146I54V, V82AL33F, F53L, T74PL10I, I13V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, H69K, K70R, L89MCRF01_AE
Nukoolkarn (2004)7474 RTV I54V, V82AL33F, N83DL10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89MCRF01_AE
 220220 RTV, IDV I54V, V82AG48I, F53L, L89VL10I, I13V, K20I, E35D, M36I, N37D, R41K, L63P, H69K, A71VCRF01_AE
 245245 SQV, RTV, IDV I54V, V82FL33IL10I, I13V, E35D, M36I, R41K, L63H, H69K, L89MCRF01_AE
Chantratita (2005)14-003714-0037DQ130439PINAI54V L10I, I13V, K20T, E35D, M36I, R41K, H69K, L89MCRF01_AE
 14-014614-0146DQ130511PINAM46I, I54V, L76V, V82FL33FW6R, L10I, E35D, M36I, R41K, K55R, Q61H, L63P, H69K, T74S, L89M, I93LCRF01_AE
 G530G530DQ130120PINAI54V, L90M I13V, K20V, E35N, M36I, R41K, I62V, I66F, H69K, K70R, V82I, L89MCRF01_AE
 G558G558DQ130132PINAI54V, V82AL33F, N83DL10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89MCRF01_AE
 G569G569DQ130138PINAI54V, I84VF53LL10I, I13V, I15V, K20R, E35D, M36I, R41K, D60E, L63P, I66F, H69K, A71V, L89ICRF01_AE
 G590G590DQ130153PINAI54V L10V, I13V, K20V, E35N, M36I, R41K, I62V, L63P, H69K, A71L, T74SCRF01_AE
 G602G602DQ130159PINAI54V, I84VN83DL10I, I13V, A22V, L33M, E35D, M36I, R41K, I62V, H69K, T74A, L89ICRF01_AE
 G605G605DQ130161PINAI54V, V82AL33F, Q58E, N83DL10V, I13V, E35D, M36I, R41K, H69K, L89ICRF01_AE
 G629G629DQ130177PINAG48V, I54V, V82AF53LL10I, I13V, K20R, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
 G658G658DQ130190PINAI54V, V82F, L90ML33I, L89VL10I, I13V, L19I, K20I, E35D, M36I, R41K, H69KCRF01_AE
 G707G707DQ130216PINAI54V, V82T, I84V L10I, I13A, K20I, E35D, M36I, R41K, I66F, H69K, A71V, L89MCRF01_AE
 NP237NP237DQ130321PINAM46I, I54V, L76V, V82FQ58EL10I, I13V, K20I, E35G, M36I, R41K, F53Y, K55R, L63P, H69K, L89MCRF01_AE
 NP293NP293DQ130373PINAG48M, I54V, V82AF53L, N83DL10V, I13V, G16E, K20R, A22V, E35D, M36I, P39S, R41K, I62V, L63H, H69K, I72V, L89I, T91SCRF01_AE
 NP299NP299DQ130379PINAG48V, I54V, V82A L10I, I13V, A22V, E35D, M36I, R41K, I62V, L63P, H69K, K70R, L89I, T91SCRF01_AE
 NP315NP315DQ130393PINAG48V, I54V, V82A L10I, I15V, E35D, M36I, R41K, Q61E, L63P, H69K, L89I, I93LCRF01_AE
Hsu (2005)BAA161430BAA161430AY870232IDV, SQV88G48V, I54V, V82AF53LL10I, I13V, L19LV, K20R, E35D, M36I, N37D, R41K, I62V, L63LP, H69K, A71T, T74S, L89ICRF01_AE
 BAA161449BAA161449AY870242SQV, RTV100G48GMRV, I54V, I84IV, L90MQ58QEL10I, I13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
Baxter (2006)48-41134113-30319DQ878344PINAI54V, V82A L10I, I13V, G16E, L19I, K20I, E35D, M36I, P39S, R41K, D60DE, I62V, H69K, K70R, A71IV, I72V, T74A, L89ICRF01_AE
Tee (2006)MYKL181404MYKL1814AY960954RTV, IDV I54V, V82T L10I, E35D, M36I, R41K, I62V, I66F, H69K, A71V, I72V, L89MCRF01_AE
 MYKL185504MYKL1855AY960955LPV I54V, V82FL33I, L89VL10I, I13V, Q18H, A22V, E35D, M36I, N37D, H69K, A71V, I93MCRF01_AE
von Wyl (2007)345869337EF449787PINAI54VN83DL10I, I13V, G16A, A22V, E35D, M36I, R41K, L63V, H69K, L89ICRF01_AE
Nerrienet (2014)Q0208194Q0208194JN675743LPV I54V, V82AL10FV, L33F, T74PI13V, G16GE, K20R, E35D, M36I, N37D, R41K, L63C, H69K, L89MCRF01_AE
 Q0920081Q0920081JN675744LPV M46I, I54V, V82SL24I, L33I, Q58E, L89VL10I, I13V, K20KR, E35D, M36I, N37DE, K55KR, R57K, I62V, L63P, H69K, T74SCRF01_AE
 T1022129T1022129JN675762LPV M46L, I54V, I84VL10F, V11I, L33I, Q58E, N83D, L89VT4P, I13V, K14R, K20R, A22V, E35S, M36I, R41K, D60E, I62V, L63P, H69K, A71V, T91G, Q92ECRF01_AE
 U0316214U0316214JN675765LPV G48V, I54V, V82AL89VT4S, L10I, V11L, I13V, K20I, E35D, M36I, I62IV, L63P, H69K, A71TCRF01_AE
 U0223070U0223070JN675763LPV I54V, V82A, L90ML10F, K43KT, L89VI13V, G16E, K20I, E35D, M36I, N37D, R41K, Q61H, L63R, H69K, A71T, T91SCRF01_AE
 T0929127T0929127JN675760LPV I54V, V82AL10FT12P, I13V, G16E, K20R, E35D, M36I, R41K, K45I, L63T, H69K, L89MCRF01_AE
 S0916071S0916071JN675753LPV M46I, I54V, V82F, L90M L10V, K20I, E35D, M36I, R41K, Q61H, I62V, L63C, H69K, T74S, L89ICRF01_AE
 U0302042U0302042JN675764LPV M46I, I54V, V82A, L90ML10F, L33I, K43T, N88DV11L, I13V, L19LV, K20V, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71V, T74S, L89T, T91ACRF01_AE
 R0606212R0606212JN675746LPV I54V, V82AL10F, N83DI13V, K20R, A22V, M36I, N37D, R41K, L63LP, H69K, L89I, T91ACRF01_AE
 T0506285T0506285JN675754LPV M46I, I47V, I54V, I84VL10F, L24IK20I, E35N, M36I, K55R, I62V, L63P, H69K, A71V, T74A, L89M, I93LCRF01_AE
 S0822156S0822156JN675752LPV M46L, I47V, G48V, I54V, V82T, I84VF53L, L89VL10I, I13A, K20I, M36I, R41K, L63P, I66F, H69K, A71VCRF01_AE
 T0518207T0518207JN675755LPV M46MI, I54V, V82AL10F, L33LI, Q58EI13V, E35D, M36I, H69K, K70R, L89ICRF01_AE