<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation G48V
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 28
Isolates 29
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Chantratita (2002)VL337VL337AF172706PINAG48V, V82AF53L, L89VL10I, I13V, K20I, E35D, M36I, N37D, L63P, H69K, A71V, T74SCRF01_AE
 VL245VL245AF191208PINAG48V, L90ML33F, F53L, N83DL10I, I13V, E35D, M36I, R41K, K43Q, L63P, H69K, L89ICRF01_AE
 GEN19GEN19AF191202PINAG48VL33F, F53L, N83DL10V, I13V, G16E, K20R, E35D, M36I, P39S, R41K, H69K, K70R, T74S, L89MCRF01_AE
 G70G70AF240394PINAG48V, I54V, V82AF53LL10I, I13V, K20I, E35D, M36I, R41K, H69K, T74S, L89ICRF01_AE
 G65G65AF240390PINAG48V, I54M, V82AL33F, F53L, N83DL10I, G16A, K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93LCRF01_AE
 G63G63AF240388PINAG48V, I54V, V82A L10I, I13V, A22V, E35D, M36I, R41K, I62V, L63P, H69K, L89ICRF01_AE
Ariyoshi (2003)JPN34JPN34AY900860IDV, SQV76G48V, I54IVL33LF, N83NDL10LI, I13V, I15V, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
Nukoolkarn (2004)278278 RTV, IDV G48V, I54T, V82AQ58EL10I, K20R, E35D, M36I, Q61N, L63E, H69K, T74S, L89MCRF01_AE
Chantratita (2005)G531G531DQ130121PINAG48V L10I, I13V, E35D, M36I, R41K, H69K, K70R, T74S, L89ICRF01_AE
 G629G629DQ130177PINAG48V, I54V, V82AF53LL10I, I13V, K20R, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
 G734G734DQ130228PINAG48V, I54A, V82A I13V, K20I, E35D, M36I, R41K, I62V, L63P, H69K, K70R, T74S, L89ICRF01_AE
 NP138NP138DQ130253PINAI47V, G48V, I54A, V82A L10I, I13V, G16E, L19P, K20I, E35D, M36I, R41K, H69K, A71V, I72R, L89ICRF01_AE
 NP144NP144DQ130258PINAG48V, V82AL33I, F53LL10I, I13V, E35D, M36I, R41K, H69K, T74S, L89ICRF01_AE
 NP254NP254DQ130336PINAG48V, L90MQ58EW6R, L10I, I13V, K20R, E35D, M36I, R41K, L63P, H69K, L89ICRF01_AE
 NP299NP299DQ130379PINAG48V, I54V, V82A L10I, I13V, A22V, E35D, M36I, R41K, I62V, L63P, H69K, K70R, L89I, T91SCRF01_AE
 NP315NP315DQ130393PINAG48V, I54V, V82A L10I, I15V, E35D, M36I, R41K, Q61E, L63P, H69K, L89I, I93LCRF01_AE
 NP324NP324DQ130402PINAG48V, I50V, I54S, V82AL33F, F53L, N83DL10I, I13V, K20R, E34V, E35D, M36I, I62V, I66F, H69K, T74A, L89MCRF01_AE
Hsu (2005)BAA150607BAA150607AY870152SQV, RTV78M46ML, G48V, I84IV, L90LML89VI13V, E35D, M36I, R41K, H69KCRF01_AE
 BAA150624BAA150624AY870158SQV, RTV31G48V, I84VL33F, Q58E, N83DL10V, I13V, K14KN, K20R, E35D, M36I, R41K, L63LP, H69K, L89ICRF01_AE
 BAA150627BAA150627AY870159SQV, RTV61G48V, I54IV, V82AL33F, F53L, N83DL10I, I13V, M36L, R41K, I62IV, L63P, H69K, T74S, L89IM, I93IVCRF01_AE
 BAA157678BAA157678AY870183SQV, RTV131G48VL33F, N83DI13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BAA161430BAA161430AY870232IDV, SQV88G48V, I54V, V82AF53LL10I, I13V, L19LV, K20R, E35D, M36I, N37D, R41K, I62V, L63LP, H69K, A71T, T74S, L89ICRF01_AE
 BAA161433BAA161433AY870233IDV, SQV, RTV270G48V, L90ML33F, N83DL10I, I13V, E35D, M36I, R41K, L63T, H69K, L89IMCRF01_AE
Non-B Workgroup (2005)TK5004TK5004 SQV, IDV, NFV, RTV, LPV145G48V, I54A, V82A L10I, V11VL, I13V, K14R, I15IV, K20I, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
  TK5004b SQV, IDV, NFV, RTV, LPV162G48V, I54AV, V82AL89IVL10I, V11VL, I13V, K14R, I15IV, K20I, E35D, M36I, R41K, H69K, K70R, A71ATCRF01_AE
Baxter (2006)48-14261426-30225DQ877815PINAG48V, I54A, V82A T4TS, L10I, V11L, I13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
Rawizza (2013)LL0499LL0499KF241476LPV M46L, G48V, L90ML33F, N83DL10V, I13V, K20R, E35DN, M36I, N37E, P39Q, R41K, D60E, Q61E, H69K, L89IMCRF01_AE
Nerrienet (2014)U0316214U0316214JN675765LPV G48V, I54V, V82AL89VT4S, L10I, V11L, I13V, K20I, E35D, M36I, I62IV, L63P, H69K, A71TCRF01_AE
 S0822156S0822156JN675752LPV M46L, I47V, G48V, I54V, V82T, I84VF53L, L89VL10I, I13A, K20I, M36I, R41K, L63P, I66F, H69K, A71VCRF01_AE