<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation M46L
Rx PI-naive
IncludeMixtures No
References 13
Patients 22
Isolates 22
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Huang (2003)CM243CM243AF447828None M46L I13V, E35D, M36I, R41K, K55R, H69K, L89MCRF01_AE
Eshleman (2004)Thai208Thai208AY444226None M46L K20KR, E35D, M36I, R41K, H69K, L89MCRF01_AE
Chang (2008)TW2458TW2458EU164918None M46L E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
Palacios (2008)1235212352 None M46L I13V, E35D, M36I, R41K, K55R, L63P, H69K, L89MCRF01_AE
Yebra (2009)SP99-396546SP99-396546EU545194None M46LL33II13V, E35D, M36I, P39S, R41K, R57K, H69K, L89MCRF01_AE
Hattori (2010)C07-2069036C07-2069036AB868027None M46L I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
Phan (2010)NB15NB15AB519532None M46L Q2E, I13V, G16E, M36I, N37K, R41N, K55R, I62V, H69K, A71V, I72R, L89M, I93LCRF01_AE
Su (2011)GXNN1256GXNN1256HQ588259None M46L I13V, G16E, E35D, M36I, N37K, R41S, K55R, H69K, L89MCRF01_AE
Ye (2011)BJ061117BJ061117JF906562None M46L K20R, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BJ07235BJ07235JF906591None M46L K20R, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BJ07397BJ07397JF906634None M46L K20R, E35D, M36I, R41K, Y59F, H69K, L89MCRF01_AE
 BJ07436BJ07436JF906644None M46L K20R, E35D, M36I, R41K, H69K, L89MCRF01_AE
Trinh (2012)VN-107VN-107GQ161881None M46L G16A, K20R, E35D, M36I, N37D, H69K, K70R, L89M, I93LCRF01_AE
Kiertiburanakul (2013)R73162R73162KC810439None M46L I13V, E35D, M36I, R41K, I62V, L63H, H69K, L89MCRF01_AE
 R71227R71227KC921457None M46L I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 R41110R41110KC970878None M46L I13V, E35D, M36I, R41K, L63P, H69K, L89M, L97ICRF01_AE
 R74099R74099KC791318None M46L I13V, E35D, M36I, R41K, K55KR, L63A, H69K, L89MCRF01_AE
Li (2013)28272827JQ901041None M46L K20R, E35D, M36I, R41K, H69K, L89MCRF01_AE
 28412841JQ901052None M46L E35D, M36I, R41K, H69R, L89M, T91ICRF01_AE
 28432843JQ901054None M46L K20R, E35D, M36I, R41K, H69K, L89MCRF01_AE
 28472847JQ901056None M46L L19Q, K20R, E34EK, E35D, M36I, G40GE, R41K, H69K, L89MCRF01_AE
Li (2013)22652265JQ302727None M46L I13V, K14R, G16E, E35D, M36I, N37K, R41S, K55R, H69K, I72V, L89MCRF01_AE