<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation M46I
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 10
Isolates 11
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Ariyoshi (2003)JPN35JPN35AY900862IDV, NFV140M46I, L90M L10V, I13V, K20T, E35D, M36I, R41K, Q61H, L63P, I64V, H69K, K70R, T74S, R87X, L89M, I93LCRF01_AE
 JPN39JPN39AY900865NFV200M46I, N88SL10FI13V, K20I, E35D, M36I, R41RK, I64V, H69K, T74S, V77VI, L89M, I93LCRF01_AE
 JPN21JPN21A IDV, NFV124M46I, N88SL10F, T74TP, L89VK20I, M36I, L63LP, H69K, I85V, I93LCRF01_AE
  JPN21BAY900869IDV, NFV132M46I, N88SL10F, L89VK20I, M36I, H69K, I85V, I93LCRF01_AE
 JPN25JPN25AY900874NFV73M46I, N88SL10F, L33I, Q58QE, L89VI13V, K20T, E35D, M36I, R41K, I62IV, H69KCRF01_AE
Tee (2006)MYKL140903MYKL1409AY960934PINAM46I I13V, M36I, R41K, H69K, L89MCRF01_AE
 MYKL182204MYKL1822AY960956RTV, IDV M46I, I84VL89VL10I, I13A, K14R, K20I, E35D, M36I, R41K, K55R, I66F, H69K, A71TCRF01_AE
 MYKL195804MYKL1958AY960959RTV, IDV M46I, L76V I13V, K14R, K20I, E35N, M36I, R41K, K55R, R57K, L63P, H69K, K70R, I72V, L89MCRF01_AE
Ferradini (2011)50789PRHM026303APV, LPV24M46I, L76V, I84VL10FI13V, G16E, E21K, E35D, M36I, R41K, H69K, I72R, L89ICRF01_AE
Barber (2012)7740677406JQ361675LPV M46IL10F, T74TPI13V, I15IV, E35D, M36I, R41K, L63C, H69K, N83S, L89MCRF01_AE
El Annaz (2012)1376113761.PRJN185269IDV52M46I, L76V I13V, K20I, E35D, M36I, N37D, I62IV, L63P, I66F, H69K, L89MCRF01_AE