<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation K43R
Rx PI-naive
IncludeMixtures No
References 24
Patients 51
Isolates 61
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Lan (2003)NTHvr29NTHvr29AY238176None  V11VII13V, G16E, K20KR, E35D, M36I, R41K, K43R, R57K, H69K, K70R, L89MCRF01_AE
 NTHvr43NTHvr43AY238149None   I13V, K20R, E35D, M36I, R41K, K43R, L63C, H69K, L89M, C95VCRF01_AE
 NTHvr90NTHvr90AY238303None   G16E, E35D, M36I, R41K, K43R, I62IM, L63C, H69K, L89MCRF01_AE
 NTHvr91NTHvr91AY238304None   I13IV, G16GE, K20R, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Maljkovic (2003)MI_Pat1698SE14962AY165194None   I13V, M36I, N37S, R41K, K43R, Q61H, H69K, L89MCRF01_AE
Tovanabutra (2003)02TH_OUR133102_1331AF529572None  L33II13V, E35D, M36I, R41K, K43R, H69K, T74S, L89MCRF01_AE
Eshleman (2004)Thai207Thai207AY444225None   I13V, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Snoeck (2004)BE29BE29 None   I13V, K20KR, M36I, R41K, K43R, H69K, L89MCRF01_AE
Liu (2007)fj52fj52EF432685None   L10I, G16E, M36I, R41K, K43R, R57K, Q61D, A71T, I72R, I93LCRF01_AE
 fj53fj53EF432686None   L10I, I13V, E35D, M36I, R41K, K43R, L63P, H69K, V82I, L89M, I93VCRF01_AE
Chang (2008)TW5407aTW5407a None   I13V, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Ayouba (2009)R20R20_PRGQ352121None   I13V, G16E, E35D, M36I, R41K, K43R, L63C, H69K, L89MCRF01_AE
 R22R22_PRGQ352123None   G16E, E35D, M36I, R41KN, K43R, L63C, H69K, L89M, I93LCRF01_AE
 R65R65_PRGQ352162None   I13V, G16E, K20R, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Ishizaki (2009)A2_195A2_195FJ007035None   I13V, G16E, L19I, K20I, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
 A2_314A2_314gFJ007063None   I13V, M36I, R41K, K43R, H69K, K70R, L89MCRF01_AE
 A2_398A2_398FJ007085None   I13V, E35D, M36I, N37D, R41K, K43R, H69K, L89MCRF01_AE
 A2_399A2_399gFJ007086None   I13V, K20R, E35D, M36I, N37D, R41K, K43R, H69K, L89MCRF01_AE
 A35A35gaFJ007121None   I13V, E35D, M36I, N37D, R41K, K43R, H69K, V82I, L89MCRF01_AE
 A271A271FJ007243None   I13V, L19V, E35D, M36I, G40E, R41K, K43R, H69K, L89MCRF01_AE
 A2_65A2_65FJ007363None   I13V, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Vercauteren (2009)pt11186510659522GQ399906None   I13V, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Jullaksorn (2010)CR17CR17-Apr08RGQ857295None   I13V, M36I, R41K, K43R, L63P, H69K, K70R, L89ICRF01_AE
  CR17-Jul08RGQ857328None   I13V, M36I, R41K, K43R, L63P, H69K, K70R, L89ICRF01_AE
  CR17-Oct08DGQ857359None   I13V, M36I, R41K, K43R, L63P, H69K, K70R, I72V, V82I, L89ICRF01_AE
  CR17-Jan09DGQ857392None   I13V, M36I, R41K, K43R, H69K, K70R, V82I, L89ICRF01_AE
  CR17-Apr09DGQ857423None   Q7H, I13V, M36I, R41K, K43R, H69K, K70R, V82I, L89ICRF01_AE
 CR25CR25-Apr08DGQ857303None   E35D, M36I, R41K, K43R, L63P, H69K, L89M, I93LCRF01_AE
 CR36CR36-Jul08DGQ857343None   I13V, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
  CR36-Oct08DGQ857375None   I13V, I15V, L19V, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
  CR36-Jan09DGQ857408None   I13V, I15V, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
  CR36-Apr09DGQ857435None   L10I, I13V, G16E, L19I, E35D, M36I, R41K, K43R, H69K, K70R, L89MCRF01_AE
 CR07CR07-Jul08RGQ857321None   I13V, G16E, K20I, E35D, M36I, R41K, K43R, R57K, H69K, L89MCRF01_AE
  CR07-Oct08RGQ857351None   I13V, G16E, K20I, E35D, M36I, R41K, K43R, R57K, H69K, L89MCRF01_AE
  CR07-Jan09DGQ857384None   I13V, G16E, K20I, E35D, M36I, R41K, K43R, R57K, H69K, L89MCRF01_AE
Phan (2010)NB03NB03AB519525None   I13V, E35D, M36I, N37D, R41K, K43R, H69K, L89MCRF01_AE
 NB23NB23AB519535None   I13V, K20R, M36I, N37D, R41K, K43R, H69K, L89MCRF01_AE
 NB48NB48AB519554None   I13V, E35D, M36I, N37D, R41K, K43R, L63R, H69K, L89MCRF01_AE
 NB49NB49AB519555None   I13V, I15V, G16E, E35D, M36I, N37D, R41K, K43R, H69K, I72V, L89MCRF01_AE
 AH49AH49AB519595None   I13V, K20R, M36I, N37D, R41K, K43R, Q61E, L63P, H69K, L89M, I93LCRF01_AE
 NB06NB06AB519608None   I13V, G16E, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Towler (2010)400541-A400541-AHM037869None   I13V, G16E, K20R, E35D, M36I, R41K, K43R, H69K, K70R, L89MCRF01_AE
Zolfo (2010)A13557A 13557 M24HM565657None   L10I, I13V, G16E, L19LP, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
  A 13557 M30HM565654None   L10I, I13V, G16E, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Aghokeng (2011)SK4003-M18SK4003-M18HQ864328None   I13V, L19I, K20I, E35S, M36I, N37D, K43R, L63P, I64IM, H69K, L89MCRF01_AE
Lazaro (2011)AG-M7AG-M7HQ542617None   I13V, E35D, M36I, R41K, K43R, L63C, H69K, V82VI, L89MCRF01_AE
 DT-M15DT-M15HQ542700None   G16E, E35D, M36I, R41K, K43R, L63C, H69K, L89M, I93LCRF01_AE
Ng (2011)FREE068FREE068HQ539032None   I13V, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Caron (2012)Gab081183Gab081183HQ541932None   I13V, G17E, L19I, E35D, M36I, N37D, R41K, K43R, L63P, H69K, L89MCRF01_AE
Kijak (2012)05TH84174905TH841749JN248356None   I13V, E35D, M36I, R41K, K43R, L63S, H69K, L89M, I93TCRF01_AE
Rolland (2012)AA023a11LAA023a11LJX446974None   I13V, E35D, M36I, R41K, K43R, I62V, L63P, H69K, V82I, L89MCRF01_AE
 AA051b03LAA051b03LJX447291None   L10I, I13V, K14R, E35D, M36I, R41K, K43R, I62V, L63S, H69K, V82I, L89MCRF01_AE
 AA073a_LH5AA073a_LH5JX447512None   L10V, I13V, E35D, M36I, R41K, K43R, H69K, V82I, L89MCRF01_AE
 AA122a09LAA122a09LJX448211None   L10V, I13V, K14R, G16E, E34K, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Tran (2012)HPC050HPC050AB690955None   I13V, I15V, G16A, E35D, M36I, N37D, R41K, K43R, H69K, K70R, L89MCRF01_AE
Trinh (2012)VN-109VN-109GQ161883None   I13V, K20R, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
 VN-6VN-6HQ876669None   E35D, M36I, R41K, K43R, L63P, H69K, L89M, I93LCRF01_AE
Yang (2012)37253725JQ617201None   I13V, G16A, E35D, M36I, N37D, R41K, K43R, C67CY, H69K, K70R, L89MCRF01_AE
 37443744JQ617220None   W6WL, L10I, I13V, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Frentz (2013)EHR-13563EHR-13563JX299761None   I13V, E35D, M36I, R41K, W42WR, K43R, I62IV, L63PS, H69K, L89MCRF01_AE
 EHR-606204EHR-606204JX300549None   I13V, K14R, I15V, M36I, N37D, R41K, K43R, L63T, I64M, H69K, L89MCRF01_AE

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