<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation E35N
Rx PI-naive
IncludeMixtures No
References 26
Patients 49
Isolates 49
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Fonjungo (2002)CM93CM93AF406730None   I13V, K20R, E35N, M36I, N37D, R41K, H69K, L89M, I93LCRF01_AE
Lan (2003)NTHvr88NTHvr88AY238301None   G16GE, E35N, M36I, R41K, H69K, L89MCRF01_AE
Tee (2006)MYKL147703MYKL1477AY960938None   I13V, E35N, M36I, R41K, Y59D, H69K, I72V, T74S, L89M, I93LCRF01_AE
Sirivichayakul (2008)BED-32BED-32PrJQ364284None   G16E, E35N, M36I, R41K, L63S, H69K, I72V, I93LCRF01_AE
 BED-36BED-36PrJQ364288None   G16E, E35N, M36V, R41K, L63S, H69K, L89M, I93LCRF01_AE
 NBC-10NBC-10PrJQ364310None   I13V, G16E, E35N, M36I, R41K, H69K, K70R, L89MCRF01_AE
Aghokeng (2009)DD0242DD0242GU191643None   I13V, G16E, E35N, M36I, N37D, R41K, K45R, H69K, I72R, L89MCRF01_AE
Ayouba (2009)R02R02_PRGQ352110None   G16E, E35N, M36I, R41K, L63C, H69K, L89MCRF01_AE
 R43R43_PRGQ352143None   I13V, G16E, E35N, M36I, R41K, K45R, L63C, H69K, L89MCRF01_AE
Ishizaki (2009)A253A253aFJ007237None   I13V, E35N, M36I, R41K, H69K, L89MCRF01_AE
Koyalta (2009)19TCHAD-19FJ688178None   I13V, G16E, L19I, E35N, M36I, N37D, R41K, K45R, R57K, L63H, H69K, I72V, V75I, L89MCRF01_AE
Liao (2009)VNAG22097VNAG220FJ185256None   I13V, E35N, M36I, N37D, R41K, H69K, L89MCRF01_AE
 VNAG22197VNAG221FJ185257None   I13V, E35N, M36I, N37D, R41K, H69K, L89M, I93MCRF01_AE
 VNAG22397VNAG223FJ185258None   I13V, E35N, M36I, R41K, H69K, L89MCRF01_AE
Nouhin (2009)KC55KC55PROTFJ531988None   L5LF, I15Y, E35N, M36I, R41K, L63C, H69K, V82I, L89M, I93LCRF01_AE
Dean (2011)IVVI7390IVVI7390JQ312419None   T12TA, I15IV, G16E, E35N, M36I, R41K, R57K, L63C, H69K, I93LCRF01_AE
Lazaro (2011)DN-M3DN-M3HQ542656None   I13V, G16A, E35N, M36I, N37D, R41K, H69K, L89MCRF01_AE
Ng (2011)HM007HM007HQ539042None   I13V, E35N, M36I, R41K, H69K, I72V, L89MCRF01_AE
Caron (2012)Gab082111Gab082111HQ541935None   I13V, L19I, E35N, M36L, N37D, R41K, L63P, H69K, L89MCRF01_AE
 Gab091183Gab091183JN705007None   E35N, M36V, N37D, R41K, L63G, H69K, L89MCRF01_AE
Chen (2012)YN10DH0119YN10DH0119JQ658739None   G16E, E35N, M36I, R41K, G49E, G51E, V56I, E65K, H69K, L89M, I93LCRF01_AE
Rolland (2012)AA106c02LAA106c02LJX448011None   E35N, M36I, R41K, R57K, H69K, L89MCRF01_AE
Ssemwanga (2012)RCC_TDR_828529RCC_TDR_828529JQ266054None   L10I, I13V, K14R, G16E, E35N, M36I, P39S, R41K, R57K, H69K, K70E, L89MCRF01_AE
Tran (2012)HPA190HPA190AB690902None   L10V, I13V, G16E, E35N, M36I, R41K, H69K, L89MCRF01_AE
Yang (2012)GZ198GZ198JN848902None   G16E, E35N, M36I, R41K, I62V, H69K, L89M, I93LCRF01_AE
Youngpairoj (2012)cm161bbcm161bbDQ166434None   I13V, K20R, E35N, M36I, N37D, R41K, L63S, H69K, L89MCRF01_AE
Billong (2013)MR087MR087KF192215None   I13V, E35N, M36I, N37DE, R41K, K43KR, H69K, L89MCRF01_AE
 MR016MR016KF192226None   E35N, M36I, N37D, R41K, L63S, H69K, L89MCRF01_AE
 MR078MR078KF192231None   L10IV, I13V, L19I, E35N, M36I, N37D, R41K, K43R, L63A, H69K, L89MCRF01_AE
 MR025MR025KF192213None  L33FI13V, K14R, E35N, N37E, R41K, H69K, V77I, L89M, I93MCRF01_AE
 MR015MR015KF192223None  L33LFT12I, I13V, Q18QE, L19LV, E35N, M36I, N37D, R41K, L63LP, H69K, I72IT, L89MCRF01_AE
Frentz (2013)EHR-779261EHR-779261JX300883None   I13V, E35N, M36I, N37D, R41K, L63P, H69K, L89MCRF01_AE
Kiertiburanakul (2013)R41179R41179KC970906None   I13V, E35N, M36I, R41K, L63P, H69K, L89MCRF01_AE
 R71TS264R71TS264KC921733None   L10I, G16E, E35N, M36I, R41K, L63S, H69K, I93LCRF01_AE
 R71TS226R71TS226KC921697None   I13V, E35N, M36I, N37D, R41K, H69K, L89MCRF01_AE
 R71TS144R71TS144KC921621None   G16E, E35N, M36I, R41K, L63S, H69K, I93LCRF01_AE
 R75043R75043KC962515None   G16E, E35N, M36I, R41K, L63S, H69K, I72IV, L89M, I93LCRF01_AE
 R41158R41158KC970895None   G16E, E35N, M36I, P39T, R41K, H69K, L89MCRF01_AE
 R72018R72018KC867569None   L10I, G16E, E35N, M36I, R41K, L63S, H69K, I93LCRF01_AE
 R71TS105R71TS105KC921583None   I13V, G16E, K20I, L33V, E35N, M36I, R41K, R57K, H69K, K70R, I72V, L89M, I93VCRF01_AE
 R73206R73206KC810482None   I13V, E35N, M36I, N37D, R41K, H69K, L89MCRF01_AE
 R74018R74018KC791238None   I13V, I15V, G16E, K20I, E35N, M36I, R41K, Q61E, L63P, H69K, K70R, I72V, L89MCRF01_AE
 R71TS135R71TS135KC921612None   G16E, E35N, M36V, R41K, L63S, H69K, I93LCRF01_AE
 R71253R71253KC921480None   G16E, E35N, M36I, R41K, L63S, H69K, I93LCRF01_AE
 R71TS240R71TS240KC921711None   I13V, K20I, E35N, M36I, R41K, K43R, R57K, H69K, K70R, L89MCRF01_AE
 R72231R72231KC857052None   G16E, E35N, M36I, R41K, L63S, H69K, I93LCRF01_AE
Kiptoo (2013)KTL058KTL058KC517059None   I13V, G16GE, E35N, M36I, R41K, R57K, H69K, L89MCRF01_AE
Li (2013)21152115JQ302617None   G16GE, E35N, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
Wu (2013)WHP68WHP68KC203287None   G17E, E35N, M36I, R41K, I62V, H69K, L89MCRF01_AE