<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L33F
Rx PI-naive
IncludeMixtures No
References 34
Patients 81
Isolates 82
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Ariyoshi (2003)JPN24JPN24AY900872None  L33FT12S, I13V, M36I, N37D, R41K, K45KE, H69K, K70R, L89M, I93LCRF01_AE
Lan (2003)NTHvr53NTHvr53AY238151None  L33FE35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
Hsu (2005)LYH_AY870218BAA161407AY870218None  L33FI13V, G16E, E35D, M36I, R41K, L63S, H69K, K70R, L89I, I93LCRF01_AE
Ly (2005)NL_KHM_CA49KHM_CA49DQ013555None  L33FI13V, K14E, E35D, M36I, R41K, H69K, L89M, I93IFCRF01_AE
 NL_KHM_CD14KHM_CD14DQ013644None  L33FI13V, K14R, M36I, R41K, H69K, L89M, I93LCRF01_AE
Tee (2005)04MYKL161204_1612AY904565None  L33FI13V, M36I, R41K, H69K, L89M, I93LCRF01_AE
 04MYKL166304_1663AY904569None  L33FL10I, I13V, M36I, R41K, I62V, H69K, K70R, L89MCRF01_AE
Gatanaga (2007)C04-51110220-1C04-51110220-1AB640319None  L33FL10I, I13V, K14R, I15L, E35D, M36IV, R41K, K55R, L63P, H69K, K70R, L89M, I93VCRF01_AE
Liu (2007)fj26fj26EF432672None  L33FI13V, E35D, M36I, R41K, K55R, L63P, H69K, I72V, L89M, L97F, N98KCRF01_AE
 fj44fj44EF432677None  L33FI13V, M36I, R41K, L63I, H69K, V77I, L89M, I93LCRF01_AE
 fj03fj03EF432725None  L33FI13V, K14R, E35D, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
Bao (2008)YUN01-14YUN01-14AM886190None  L33FL19M, M36I, R41K, L63P, H69K, K70R, L89M, I93LCRF01_AE
 YUN01-25YUN01-25AM886201None  L33FV11A, I13V, M36I, N37D, I62V, H69K, L89M, I93LCRF01_AE
 YUN01-16YUN01-16AM886192None  L33FI13V, M36I, R41K, L63P, H69K, K70R, L89M, I93VCRF01_AE
Chang (2008)TW5112TW5112EU164906None  L33FI13V, M36I, N37S, R41K, H69K, L89M, I93VCRF01_AE
 TW3210aTW3210a None  L33FI13V, K20R, M36I, R41K, H69K, L89M, I93VCRF01_AE
 TW9199aTW9199a None  L33FI13V, G17E, M36I, R41K, R57K, H69Q, I72L, L89MCRF01_AE
Holguin (2008)SP18-348212SP18-348212EU255503None  L33FL10M, T12TA, I13V, K14KR, E35D, M36I, N37ND, R41K, I62IV, G68E, H69Q, L89M, I93VCRF01_AE
Ibe (2008)261261AB356105None  L33FT4TS, I13V, M36I, R41K, H69K, K70R, V77VI, L89M, I93LCRF01_AE
Sirivichayakul (2008)BED-15BED-15PrJQ364272None  L33FI13V, G17D, E35D, M36I, R41K, K45R, L63P, H69K, L89M, I93VCRF01_AE
Auwanit (2009)13AE-PR13FJ463512None  L33FI13V, M36I, R41K, H69K, L89M, I93VCRF01_AE
 156AE-PR156FJ463545None  L33FI13V, E35D, M36I, R41K, R57K, C67S, H69K, L89MCRF01_AE
Ayouba (2009)FD0458FD0458PIGQ352068None  L33FI13V, E35D, M36I, R41K, H69K, L89M, I93VCRF01_AE
 FD0645FD0645PIGQ352088None  L33FI13V, E35D, M36I, R41K, R57K, C67Y, H69K, K70R, L89M, I93IVCRF01_AE
 FD0646FD0646PIGQ352080None  L33FI13V, E35D, M36I, P39Q, R41K, H69K, L89M, I93V, L97ICRF01_AE
Fujisaki (2009)1818AB442230None  L33FI13V, E35D, M36I, R41K, R57K, H69K, K70KR, L89IMCRF01_AE
 585585AB442256None  L33FL10LR, I13V, E35D, M36I, R41K, R57K, L63P, H69HKNQ, V77VIM, L89M, I93VCRF01_AE
 665665AB442323None  L33FL10I, I13V, M36I, R41K, K55KR, H69K, K70KR, V82I, L89M, I93VCRF01_AE
Tu (2009)37PBMC37EU518279None  L33FL10V, I13V, M36V, P39Q, R41K, H69K, L89M, I93VCRF01_AE
  plasma37EU518328None  L33FL10V, I13V, M36V, P39Q, R41K, H69K, L89M, I93VCRF01_AE
Vercauteren (2009)pt326jow3TbcW88GQ400698None  L33FI13V, M36L, P39PT, R41K, H69K, L89M, I93VCRF01_AE
Han (2010)LN138LN138FJ531428None  L33FI13V, G16A, L19M, E35D, M36I, R41K, G68E, H69K, K70R, L89M, I93LCRF01_AE
Hattori (2010)C07-2066336C07-2066336AB864078None  L33FI13V, M36I, R41K, L63I, H69K, L89M, I93LCRF01_AE
 C06-2066297C06-2066297AB864032None  L33FL10LV, I13V, M36I, N37ND, R41K, L63P, H69K, L89M, I93VCRF01_AE
 C06-2066290C06-2066290AB864028None  L33FI13V, R41K, L63P, H69K, I72M, L89M, Q92ECRF01_AE
 D08-2031034D08-2031034AB865912None  L33FT12P, I13V, M36I, N37ND, R41RK, L63P, C67S, H69K, K70R, L89M, I93LCRF01_AE
Phan (2010)NB56NB56AB519557None  L33FI13V, M36I, R41K, E65D, H69K, L89M, I93VCRF01_AE
Zhang (2010)05178CNsd05178GQ443562None  L33FI13V, E35D, M36I, R41K, L63LP, H69K, K70KR, L89M, I93VCRF01_AE
Hamers (2011)CP076301591CP076301591HQ993629None  L33FL10V, E35D, M36I, N37D, R41K, K45R, R57K, Q61H, L63P, H69K, I72IT, I85V, L89MCRF01_AE
Lazaro (2011)VT-M2VT-M2HQ542634None  L33FG16E, K20R, M36I, R41K, L63C, H69K, L89M, I93LCRF01_AE
 TG-M16TG-M16HQ542684None  L33FI13V, G16A, M36I, N37D, R41K, L63F, H69K, L89M, I93L, L97PCRF01_AE
Ng (2011)FREE065FREE065HQ539030None  L33FI13V, G16E, N37S, P39S, L63S, H69K, K70R, L89M, I93LCRF01_AE
Ngo-Giang-Huong (2011)PHPT0375PHPT0375PR-RTHQ996498None  L33FL10I, I13V, E35D, M36I, R41K, G68E, H69K, K70R, L89IMCRF01_AE
Chen (2012)YN09DH0056YN09DH0056JQ658525None  L33FI13V, K14N, L23LP, E35D, M36I, H69K, I72IV, L89M, I93VCRF01_AE
 YN10DH0024YN10DH0024JQ658649None  L33FI13V, M36I, P39Q, R41K, R57RK, L63P, H69K, L89M, I93LCRF01_AE
Rolland (2012)AA006a03AA006a03JX446737None  L33FI13V, M36I, N37S, P39S, R41K, H69K, L89M, I93VCRF01_AE
 AA017a_wg4AA017a_wg4JX446902None  L33FI13V, E35D, M36I, R41K, H69K, L89M, T91ICRF01_AE
 AA081a_01LAA081a_01LJX447621None  L33FI13V, E35D, M36I, P39S, R41K, R57K, H69K, L89MCRF01_AE
 AA104a_LH21AA104a_LH21JX447973None  L33FI3L, L10I, I13V, M36I, R41K, H69K, K70R, L89M, I93L, G94DCRF01_AE
Zeng (2012)CN1225CN1225JQ028235None  L33FI13V, M36I, R41K, H69K, L89M, I93VCRF01_AE
Aghokeng (2013)HJ3392HJ3392JX983029None  L33FI13V, E35N, M36I, N37D, P39Q, H69K, K70R, L89MCRF01_AE
Billong (2013)MR025MR025KF192213None  L33FI13V, K14R, E35N, N37E, R41K, H69K, V77I, L89M, I93MCRF01_AE
Frentz (2013)EHR-36580EHR-36580JX300151None  L33FI13V, Q18QH, M36I, R41K, L63T, H69K, L89MCRF01_AE
Kiertiburanakul (2013)R12055R12055KC994203None  L33FI13V, M36I, R41K, H69K, V77VI, L89M, I93VCRF01_AE
 R73188R73188KC810464None  L33FI13V, M36I, R41K, L63LI, I64V, H69K, L89M, I93LCRF01_AE
 R41194R41194KC970951None  L33FI13V, E35D, M36I, R41K, K43R, R57K, H69K, K70R, L89M, L97ICRF01_AE
 R41002R41002KC970859None  L33FL10I, M36I, R41K, L63T, H69K, L89M, I93L, L97ICRF01_AE
 R75040R75040KC962517None  L33FG16A, R41K, K43KR, H69K, L89M, I93LCRF01_AE
 R71TS222R71TS222KC921693None  L33FL10I, T12P, I13V, L19V, M36I, R41K, K43R, H69K, L89MCRF01_AE
 R42055R42055KC971027None  L33FL5F, I13V, M36T, R41K, H69K, L89MCRF01_AE
 R71TS251R71TS251KC921721None  L33FI13V, M36I, N37S, R41K, K45R, H69K, L89M, I93LCRF01_AE
 R41063R41063KC970871None  L33FL10I, I13V, M36I, R41K, I64L, H69K, K70R, L89MCRF01_AE
 R73017R73017KC810562None  L33FR41K, H69K, L89M, I93LCRF01_AE
 R71127R71127KC921840None  L33FI13V, E35D, M36I, R41K, L63T, H69K, L89M, I93VCRF01_AE
 R71TS209R71TS209KC921680None  L33FI13V, M36I, R41K, K45R, I62V, L63P, I64L, C67D, H69K, L89M, I93LCRF01_AE
 R74131R74131KC791350None  L33FI13V, A28V, M36I, N37NS, R41K, K55KR, H69K, L89M, I93VCRF01_AE
 X12028X12028KC994363None  L33FI13V, M36I, N37I, R41K, H69K, L89M, I93VCRF01_AE
 R75031R75031KC962522None  L33FI13V, M36I, P39Q, R41K, H69K, L89M, L97ICRF01_AE
 R12118R12118KC994258None  L33FI13V, M36I, N37T, R41K, H69K, L89M, I93VCRF01_AE
 R71TS212R71TS212KC921683None  L33FI13V, K14R, K20I, M36I, R41K, K43R, H69K, L89M, I93VCRF01_AE
 R73121R73121KC810407None  L33FI13V, M36I, R41K, H69K, K70KR, L89M, I93VCRF01_AE
 R71TS146R71TS146KC921623None  L33FI13V, M36I, N37S, R41K, H69K, L89M, I93LCRF01_AE
 R72245R72245KC857066None  L33FI13V, G16E, M36I, P39Q, R41K, L63I, H69K, L89M, I93LCRF01_AE
 R72155R72155KC856983None  L33FI13V, E35ED, M36I, R41K, L63LAPV, E65ED, H69K, L89M, I93VCRF01_AE
 R72255R72255KC857076None  L33FL10V, I13V, K14R, E35ED, M36I, N37NS, R41K, H69K, K70R, L89M, I93VCRF01_AE
 R72263R72263KC857082None  L33FI13V, K20R, M36I, R41K, L63LI, I64IV, H69K, L89M, I93LCRF01_AE
 R72214R72214KC857035None  L33FI13V, E35D, M36T, R41K, L63P, H69K, K70R, L89MCRF01_AE
Ong (2013)08MYKL03708MYKL037KC181261None  L33FL5F, I13V, M36T, R41K, H69K, L89MCRF01_AE
 08MYKL00208MYKL002KC181245None  L33FI13V, E35D, R41K, L63V, H69K, L89MCRF01_AE
Wu (2013)WHP55WHP55KC203280None  L33FI13V, Q18L, L19M, M36I, R41K, L63I, H69K, L89M, I93LCRF01_AE
 WHP70WHP70KC203288None  L33FI13V, Q18L, L19M, M36I, R41K, C67Y, H69K, L89M, I93LCRF01_AE
 WHP54WHP54KC203279None  L33FI13V, Q18L, L19M, M36I, R41K, L63LI, C67CY, H69K, L89M, I93LCRF01_AE