<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation K20R
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 13
Isolates 15
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG108108_w28 NFV28  L10V, I13V, G16E, K20R, E35D, M36I, R41K, H69K, L89MCRF01_AE
Ariyoshi (2003)JPN26JPN26AY900687NFV, IDV51  L10LI, K20R, E35D, M36I, R41K, H69K, L89M, I93LCRF01_AE
 JPN44JPN44A IDV, SQV, RTV88  K20R, E35D, M36I, N37D, L63P, H69K, L89M, I93LCRF01_AE
  JPN44BAY900691IDV, SQV, RTV, LPV204  K20R, E35D, M36I, N37D, L63P, H69K, L89M, I93LCRF01_AE
 JPN14JPN14AY900697NFV7  K20R, E35D, M36I, R41K, K45R, H69X, L89M, I93LCRF01_AE
 JPN15JPN15AY900698NFV, IDV113I54V, L90ML10F, L33II13V, K20R, E35D, M36I, R41K, I64V, H69K, L89MCRF01_AE
Montes (2004)MB_patBRI00_BRI706AJ577745SQV, NFV, RTV111  Q7P, I13V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, H69K, T74S, L89MCRF01_AE
  01_BRI705AJ577746SQV, NFV, RTV, LPV146I54V, V82AL33F, F53L, T74PL10I, I13V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, H69K, K70R, L89MCRF01_AE
Hsu (2005)BAA148363BAA148363AY870148SQV, RTV35I84V, L90M L10V, I13V, K20R, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
 BAA150624BAA150624AY870158SQV, RTV31G48V, I84VL33F, Q58E, N83DL10V, I13V, K14KN, K20R, E35D, M36I, R41K, L63LP, H69K, L89ICRF01_AE
 BAA161429BAA161429AY870231RTV, IDV78  L10V, K20R, E35D, M36I, R41K, H69K, I72V, L89MCRF01_AE
 BAA161430BAA161430AY870232IDV, SQV88G48V, I54V, V82AF53LL10I, I13V, L19LV, K20R, E35D, M36I, N37D, R41K, I62V, L63LP, H69K, A71T, T74S, L89ICRF01_AE
Non-B Workgroup (2005)TH_220TH_220AY605624IDV   L10I, I13V, G16E, K20R, E35D, M36I, R41K, I62V, H69K, L89M, L97ICRF01_AE
Baxter (2006)48-41434143-30408DQ878375PINAG48V, I54A, V82S L10V, I15V, L19I, K20R, E35D, M36I, R41K, I62V, L63V, H69K, T74S, L89M, I93LCRF01_AE
Ferradini (2011)40739PRHM026302LPV24V82A L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63C, H69K, T74A, L89MCRF01_AE