<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation K20I
Rx PI-naive
IncludeMixtures No
References 50
Patients 129
Isolates 132
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Lan (2003)NTHvr109NTHvr109AY238274None   I13IV, K20I, E35D, M36I, R41K, H69K, V82VI, L89MCRF01_AE
Hsu (2005)BAA157666BAA157666AY870172None  L89VI13V, K20I, E35D, M36I, R41K, H69KCRF01_AE
Ly (2005)NL_KHM_CA52KHM_CA52DQ013558None   I13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 NL_KHM_CD20KHM_CD20DQ013650None   I13V, K20I, M36I, R41K, H69K, K70R, V82I, L89MCRF01_AE
 NL_KHM_HM21KHM_HM21DQ013587None   I13V, K20I, E35D, M36I, P39PS, R41K, H69K, L89MCRF01_AE
Jayaraman (2006)1-00-00981-00-0098 None   I13V, I15L, L19Q, K20I, E21T, M36I, R41K, H69K, V82I, L89MCRF01_AE
Tee (2006)MYKL140203MYKL1402AY960933None   I13V, K20I, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
  04MYKL1402.1AY960962None   I13V, K20I, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
  04MYKL1402.2AY960963None   I13V, K20I, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
Brumme (2007)1264PR_1264EF368574None   I13V, L19I, K20I, E35D, M36I, R41K, H69K, I72IV, L89MCRF01_AE
Derache (2007)11781178EF064463None   L10V, I13V, L19P, K20I, M36L, P39S, R41K, H69K, K70R, L89MCRF01_AE
 12541254EF064501None   I13V, K14R, G16E, K20I, M36I, R41K, H69K, K70R, L89MCRF01_AE
 12661266EF064505None   I13V, K14R, K20I, M36I, R41K, L63P, C67H, H69K, L89ICRF01_AE
 12711271EF064510None  V11II13V, K14R, G16E, K20I, E35G, M36I, R41K, H69K, L89MCRF01_AE
Gatanaga (2007)C04-51110192-1C04-51110192-1AB640292None   I13V, K20I, E35D, M36I, R41K, L63V, I64M, H69K, L89MCRF01_AE
 C03-5555-5546-1C03-5555-5546-1AB640386None   I13V, K20I, E35D, M36I, R41K, R57K, H69K, K70R, T74S, L89MCRF01_AE
Lin (2007)4V934V93EF078241None   L10H, I13V, K20I, E35D, M36I, R41K, I64M, H69K, I72M, L89MCRF01_AE
 4v3474v347EF078264None   I13V, I15V, G16E, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
Liu (2007)fj07fj07EF432662None  V11II13V, G16E, K20I, M36I, R41K, I64V, H69K, L89I, Q92RCRF01_AE
 fj09fj09EF432664None   I13V, I15V, G16E, K20I, E35D, M36I, R41K, H69K, I72V, G73D, L89M, Q92KCRF01_AE
 fj78fj78EF432702None   I13V, K14R, K20I, E21K, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
Chang (2008)TW4794TW4794DQ640281None   I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
 TW0301aTW0301a None   I13V, K20I, E35D, M36I, R41K, I62V, H69K, K70R, T74S, V77VI, L89MCRF01_AE
Derache (2008)BKO-987BKO-987EU330702None   I13V, K14R, G17E, K20I, M36I, N37D, R41K, H69K, K70R, L89MCRF01_AE
Ibe (2008)159159AB356207None   I13V, K20I, M36I, R41K, H69K, V82I, L89MCRF01_AE
 437437AB356406None   V11A, I13V, K20I, E35D, M36I, R41K, L63LI, H69K, K70R, T74S, L89M, T91ACRF01_AE
 527527AB356463None   I13V, K14KR, I15IL, K20I, M36I, R41K, L63S, H69K, V82VI, L89M, T91VCRF01_AE
Nguyen (2008)030VN030 None   I13V, G16E, K20I, M36I, R41K, G52X, H69K, K70R, T74A, L89M, I93LCRF01_AE
 009VN009 None   I13V, K20I, E35D, M36I, R41K, H69K, L89M, F99XCRF01_AE
Sirivichayakul (2008)BED-37BED-37PrJQ364289None   I13V, K20I, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
Ayouba (2009)R21R21_PRGQ352122None   I13V, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 R32R32_PRGQ352133None   I13V, I15V, K20I, M36I, R41K, L63P, H69K, V82I, L89M, I93LCRF01_AE
Ishizaki (2009)C29C29FJ006968None   I13V, G16A, K20I, E35D, M36V, R41K, H69K, L89MCRF01_AE
 A2_22A2_22tcFJ006988None   I13V, K20I, E35D, M36I, R41K, I62V, L63P, H69K, L89MCRF01_AE
 A2_195A2_195FJ007035None   I13V, G16E, L19I, K20I, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
 A118A118FJ007158None   I13V, I15L, K20I, M36I, R41K, Q61E, H69K, L89MCRF01_AE
 A127A127FJ007162None   L10I, I13V, G16E, K20I, M36I, R41K, L63V, H69K, L89MCRF01_AE
 A231A231aaagFJ007222None   I13V, K20I, M36I, R41K, H69K, L89MCRF01_AE
 A360A360aFJ007296None  V11II13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
Lee (2009)S07017S07017EU715191None   I13V, K20I, E35D, M36I, R41K, C67CW, H69K, K70R, V82I, L89MCRF01_AE
Liao (2009)VNAG21097VNAG210FJ185251None   L10I, I13V, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
Nouhin (2009)KC06KC06PROTFJ531944None   L5LF, I13V, L19LV, K20I, T26TS, E35D, M36I, R41K, E65EK, H69K, V82I, L89MCRF01_AE
 KC57KC57PROTFJ531990None   I13V, K20I, M36I, R41K, H69K, K70R, I72IV, V82I, L89MCRF01_AE
Vercauteren (2009)pt262MtEEcRdta4GQ400762None   L10I, I13V, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
Bonura (2010)1193_881193_88GU969548None  V11IL10V, T12A, I13V, G16E, K20I, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Carr (2010)0096MA01CM.0096MAGU201497None   I13V, G17E, K20I, E34K, M36I, P39S, R57K, Q61N, I62L, L63S, C67E, H69K, V77I, L89MCRF01_AE
Phan (2010)O908O908AB519479None   I13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 O911O911AB519482None   T12A, I13V, G16E, K20I, E35D, M36I, R41K, L63S, H69K, L89M, T91ACRF01_AE
 O922O922AB519493None   I13V, G16E, K20I, E35D, M36I, R41K, L63P, H69K, K70R, L89MCRF01_AE
 O923O923AB519494None   L10I, I13V, K20I, M36I, R41K, H69K, K70R, V82I, L89MCRF01_AE
 NB44NB44AB519550None   I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
Zhang (2010)06157CNsd06157GQ443594None   I13V, G16E, K20I, E35D, M36I, R41K, H69K, K70R, L89MCRF01_AE
Zolfo (2010)A13412A 13412 M18HM565700None   L10I, I13V, G16E, K20I, E35D, M36I, R41K, H69K, K70G, V77I, L89MCRF01_AE
  A 13412 M24HM565661None   L10I, I13V, G16E, K20I, E35DN, M36I, R41K, H69K, K70GR, V77I, L89MCRF01_AE
Aghokeng (2011)SK4003-M18SK4003-M18HQ864328None   I13V, L19I, K20I, E35S, M36I, N37D, K43R, L63P, I64IM, H69K, L89MCRF01_AE
Bontell (2011)Pat03808.VL782UiHQ852878None   I13V, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, V82I, L89MCRF01_AE
 Pat00409.VL984UHQ852912None   T12P, I13V, G16E, K20I, M36I, N37NT, P39L, R41K, L63Q, H69K, K70R, L89MCRF01_AE
Dean (2011)IVVI7074IVVI7074JQ312402None   G16E, K20I, E35D, M36I, L63C, H69K, L89MCRF01_AE
Fokam (2011)CIRCB-10232CIRCB-10232JQ796129None   I13V, K14Q, G17E, K20I, E34KT, E35D, M36I, R41RK, R57K, Q61H, L63I, I64M, H69C, K70R, I72E, P79PL, L89MCRF01_AE
Hamers (2011)CP076300763CP076300763HQ995335None   I13V, G16E, K20I, E35D, M36I, R41K, R57K, D60E, H69K, L89MCRF01_AE
Lazaro (2011)AG-M2AG-M2HQ542613None  V11II13V, G16E, K20I, E35D, M36L, R41K, Q61E, H69K, K70R, L89M, I93LCRF01_AE
 DN-M22DN-M22HQ542669None  V11II13V, I15V, G16GE, K20I, E35ED, M36I, R41K, H69K, L89MCRF01_AE
Ng (2011)HM086HM086HQ539114None   I13V, K20I, E35D, M36I, R41K, R57K, H69K, K70R, V82I, L89MCRF01_AE
 HM144HM144HQ539169None   I13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 HM152HM152HQ539176None   I13V, K20I, E35D, M36I, R57K, H69K, V82I, L89MCRF01_AE
Ngo-Giang-Huong (2011)PHPT4015PHPT4015PR-RTHQ996509None   I13V, I15V, K20I, M36I, H69K, I72E, V82I, L89MCRF01_AE
Su (2011)GXNN7219GXNN7219HQ588274None   I13V, K20I, E35G, M36I, R41K, H69K, A71T, L89TCRF01_AE
Ye (2011)BJ07639BJ07639JF906696None   I13V, L19M, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
Zeng (2011)K41K41JF505564None   I13V, I15V, K20I, E35D, M36I, R41K, H69K, K70R, I72V, V82I, L89MCRF01_AE
Chamberland (2012)C405SC405SHQ267537None   I13V, G17E, K20I, E35G, M36I, N37S, R41K, I62V, H69K, I72M, V77I, L89MCRF01_AE
 C497SC497SHQ267593None   L10I, T12A, I13V, K14R, I15V, K20I, E35D, M36I, N37S, R41K, R57K, H69Q, K70R, P79A, L89MCRF01_AE
Chen (2012)YN09DH0016YN09DH0016JQ658489None   L10I, I13V, I15V, K20I, E35D, M36I, L63P, H69K, V82I, L89M, I93VCRF01_AE
De Gascun (2012)IRL25181IRL25181JN622221None   Q7QR, L10V, I13V, G16E, K20I, E35D, M36I, N37NY, R41K, K45KN, L63V, H69K, G78GA, I85IM, L89MCRF01_AE
 IRL54561IRL54561JN622233None   L10V, T12A, I13V, G16E, K20I, E35D, M36I, R41K, L63V, H69K, L89MCRF01_AE
Nazziwa (2012)51376305137630JX499010None   I13V, K20I, E35D, M36I, N37S, R41K, R57K, H69K, T74S, L89MCRF01_AE
Rolland (2012)AA035a03LAA035a03LJX447096None   I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
 AA111a_WG11AA111a_WG11JX448059None   I13V, K14R, K20I, M36I, R41K, H69K, L89MCRF01_AE
Tran (2012)HPA160HPA160AB690893None   I13V, G16E, K20I, E35D, M36I, R41K, I64M, H69K, L89MCRF01_AE
 HPA216HPA216AB690910None   I13V, G16E, K20I, E35ED, M36I, R41K, H69K, I72V, L89MCRF01_AE
 HPV2_211HPV2_211AB690978None   I13V, G16E, K20I, E35D, M36I, R41K, H69K, K70R, L89MCRF01_AE
 HPV2_212HPV2_212AB690979None   I13V, I15L, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
Yang (2012)37133713JQ617189None   I13V, G16V, K20I, E35ED, M36I, N37D, R41K, K45KR, L63PS, H69K, K70R, L89M, I93LCRF01_AE
Yang (2012)GZ163GZ163JN848881None   T12A, I13V, G16E, K20I, M36I, R41K, H69K, L89M, Q92KCRF01_AE
Zeng (2012)CN1324CN1324JQ028264None   I13V, K14R, G16E, K20I, M36I, R41K, H69K, L89MCRF01_AE
 CN0048CN0048JQ028325None   I13V, G16E, K20I, E35D, M36I, R41K, R57K, H69K, K70R, L89MCRF01_AE
 CN1283CN1283JQ028361None   I13V, G16E, K20I, M36I, R41K, L63P, H69K, K70R, L89MCRF01_AE
Hawke (2013)9021391290213912KC238231None   L10LI, T12P, I13V, K14KT, K20I, E35D, M36I, R41K, L63P, I64V, H69KQ, L89IMCRF01_AE
Kiertiburanakul (2013)R74066R74066KC791285None   I13V, I15IV, G16A, K20I, M36I, R41RK, H69K, K70KR, I72IEKV, V82I, L89MCRF01_AE
 R72112R72112KC867647None   I13V, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 R72075R72075KC867615None   L10IV, I13V, K14R, I15V, G16E, L19M, K20I, E35D, M36I, R41K, I64M, H69K, L89MCRF01_AE
 R72052R72052KC867593None   I13V, K20I, E35D, M36I, R41K, L63PT, I64L, H69K, K70R, V82I, L89MCRF01_AE
 R72065R72065KC867605None   P9L, L10I, I13V, I15V, K20I, E35D, M36I, H69K, V82I, L89MCRF01_AE
 R74171R74171KC791390None   I13V, K20I, E35D, M36I, R41K, K45KR, H69K, T74TS, V82VI, L89MCRF01_AE
 R75033R75033KC962529None   I13V, K20I, E35DN, M36I, N37ND, R41K, I64IL, H69K, L89MCRF01_AE
 R73105R73105KC810393None   I13V, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 R12097R12097KC994239None   I13V, G17E, K20I, E35D, M36I, K43KE, L63LP, I64IM, H69K, L89MCRF01_AE
 R74049R74049KC791269None   L10I, I13V, G16E, K20I, M36I, L63S, H69K, K70R, L89M, I93VCRF01_AE
 R73TS010R73TS010KC810538None   I13V, G16E, G17D, K20I, E35D, M36I, H69K, L89MCRF01_AE
 R73092R73092KC810380None   I13V, I15L, K20I, M36I, R41K, L63LV, I64M, H69K, L89MCRF01_AE
 R71TS105R71TS105KC921583None   I13V, G16E, K20I, L33V, E35N, M36I, R41K, R57K, H69K, K70R, I72V, L89M, I93VCRF01_AE
 R74089R74089KC791308None   L10M, I13V, G17E, K20I, E35D, M36I, R41K, I62V, H69K, K70R, V82I, L89M, L97ICRF01_AE
 R12129R12129KC994267None   I13V, G16E, K20I, E35D, M36I, N37D, R41K, K43R, L63P, H69K, K70R, A71AT, L89M, Q92KCRF01_AE
 R74175R74175KC791394None  L10FI13V, I15V, G16A, K20I, E35D, M36I, R41K, H69K, I72IM, L89MCRF01_AE
 R74018R74018KC791238None   I13V, I15V, G16E, K20I, E35N, M36I, R41K, Q61E, L63P, H69K, K70R, I72V, L89MCRF01_AE
 R72082R72082KC867622None   L10I, I13V, I15V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89M, L97ICRF01_AE
 R73072R73072KC810362None   L10M, I13V, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 R41023R41023KC970880None   I13V, I15V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MCRF01_AE
 R73198R73198KC810474None   I13V, K14R, G17E, K20I, M36I, R41K, H69K, K70KR, V82VI, L89MCRF01_AE
 R73186R73186KC810462None   I13V, I15V, K20I, E35D, M36I, R41K, H69K, K70R, V82VI, L89MCRF01_AE
 R71014R71014KC921779None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 R71185R71185KC921866None   L10I, I13V, K14R, G16E, K20I, E35D, M36I, R41K, K45R, H69K, K70R, L89MCRF01_AE
 R12179R12179KC994305None   I13V, L19MV, K20I, E35ED, M36I, R41RK, H69K, K70KR, I72IM, L89MCRF01_AE
 R74111R74111KC791330None   I13V, I15IV, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
 R74135R74135KC791354None   I13V, K20I, M36I, R41K, K43R, L63S, H69K, V82I, L89IMCRF01_AE
 R71TS212R71TS212KC921683None  L33FI13V, K14R, K20I, M36I, R41K, K43R, H69K, L89M, I93VCRF01_AE
 R72003R72003KC867560None   L10I, T12P, I13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 R71TS114R71TS114KC921592None   V11C, T12H, I13A, K20I, E35D, M36I, R41K, R57K, H69K, L89MCRF01_AE
 R73038R73038KC810329None   L10I, I13V, K20I, E35D, M36I, R41K, L63P, H69A, L89MCRF01_AE
 R42075R42075KC971034None   I13V, K14R, K20I, E34A, E35D, R41K, R57K, H69K, L89MCRF01_AE
 R71TS240R71TS240KC921711None   I13V, K20I, E35N, M36I, R41K, K43R, R57K, H69K, K70R, L89MCRF01_AE
 R72219R72219KC857040None   L10I, I13V, K14R, K20I, E35D, M36I, R41K, L63LP, H69K, L89MCRF01_AE
 R72207R72207KC857028None   I13V, G16E, L19I, K20I, E35D, M36I, R41K, E65D, H69K, L89MCRF01_AE
 R72115R72115KC856949None   I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MCRF01_AE
 R72122R72122KC856954None   I13V, G16E, K20I, E35DN, M36I, N37D, R41K, H69K, K70R, I72IV, V77I, L89MCRF01_AE
 R72254R72254KC857075None   L10I, I13V, I15V, G16E, K20I, E35D, M36I, R41K, K43R, H69K, L89MCRF01_AE
Li (2013)21672167JQ302649None   I13V, I15IV, L19LQ, K20I, M36I, R41K, D60E, H69K, P79S, V82I, L89MCRF01_AE
 21112111JQ302615None   I13V, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 20302030JQ302562None   I13V, G16E, K20I, E35D, M36I, R41K, I62V, H69K, K70KR, V82I, L89MCRF01_AE
 20762076JQ302596None   L10LI, I13V, I15IV, K20I, M36I, N37D, R41K, L63P, H69K, V82I, L89M, I93VCRF01_AE
Ong (2013)09MYKL04909MYKL049KC181278None   I13V, K14R, K20I, E34A, E35D, R41K, R57K, H69K, L89MCRF01_AE
 08MYKL02008MYKL020KC181250None   I13V, I15V, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 10MYKL00810MYKL008KC181298None   I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE