<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation K20I
Rx >= 1 PI
IncludeMixtures No
References 12
Patients 69
Isolates 72
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Chantratita (2002)VL337VL337AF172706PINAG48V, V82AF53L, L89VL10I, I13V, K20I, E35D, M36I, N37D, L63P, H69K, A71V, T74SCRF01_AE
 G78G78AF240399PINAM46I, L76V, V82F L10I, I13V, K20I, E35N, M36I, R41K, Q61H, L63C, H69K, K70R, L89MCRF01_AE
 G72G72AF240395PINAG48M, I54V, V82A L10I, I13V, K20I, E35D, M36I, R41K, H69K, L89ICRF01_AE
 G70G70AF240394PINAG48V, I54V, V82AF53LL10I, I13V, K20I, E35D, M36I, R41K, H69K, T74S, L89ICRF01_AE
 G67G67AF240392PINAI54V, V82F, L90M L10I, I13V, K20I, E35N, M36I, R41K, L63P, H69K, T74S, L89M, I93MCRF01_AE
 G66G66AF240391PINAI54V, V82F, L90M L10I, I13V, K20I, E35N, M36I, R41K, L63P, H69K, T74S, L89M, I93MCRF01_AE
 G57G57AF240384PINAM46IL10FI13V, K20I, E35D, M36I, R41K, K55R, I62V, L63P, H69K, L89TCRF01_AE
 G54G54AF240381PINAI54VL89VI13V, K20I, E35D, M36I, R41K, H69KCRF01_AE
Ariyoshi (2003)JPN42JPN42A SQV104I54V, V82F, L90ML33F, I84LL10V, I13V, I15IV, G16E, K20I, E35D, M36I, N37ND, R41K, H69K, T74S, L89I, Q92KCRF01_AE
 JPN12JPN12A SQV77 Q58EI13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
  JPN12BAY900696SQV92 Q58EI13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
 JPN19JPN19BAY900861NFV77N88SL10FG16E, K20I, E35D, M36I, R41K, L63T, I64V, H69K, L89M, I93LCRF01_AE
 JPN38JPN38 IDV, NFV129I54V, V82F L10I, I13V, G16E, K20I, E35D, M36I, R41K, K45V, L63LH, H69K, K70R, L89M, F99FLCRF01_AE
 JPN39JPN39AY900865NFV200M46I, N88SL10FI13V, K20I, E35D, M36I, R41RK, I64V, H69K, T74S, V77VI, L89M, I93LCRF01_AE
 JPN21JPN21A IDV, NFV124M46I, N88SL10F, T74TP, L89VK20I, M36I, L63LP, H69K, I85V, I93LCRF01_AE
  JPN21BAY900869IDV, NFV132M46I, N88SL10F, L89VK20I, M36I, H69K, I85V, I93LCRF01_AE
 JPN41JPN41BAY900873IDV, SQV, NFV, APV195I54V, V82F, L90LM L10I, I13V, G16E, K20I, E35DN, M36I, P39Q, R41K, K45V, G48X, I62V, L63P, H69K, L89MCRF01_AE
Montes (2004)MB_patCAL00_CAL703AJ577857SQV, IDV, RTV98I84V I13V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89TCRF01_AE
Nukoolkarn (2004)220220 RTV, IDV I54V, V82AG48I, F53L, L89VL10I, I13V, K20I, E35D, M36I, N37D, R41K, L63P, H69K, A71VCRF01_AE
 321321 NFV L90M I13V, K20I, E35D, M36I, R41K, I64V, H69K, L89MCRF01_AE
Chantratita (2005)14-000114-0001DQ130423PINA  L10I, I13V, L19P, K20I, E35D, M36I, R41K, H69K, K70R, L89MCRF01_AE
 14-009514-0095DQ130468PINA  L10M, I13V, K20I, E21D, M36I, R41K, L63S, H69K, L89MCRF01_AE
 14-013414-0134DQ130499PINAL90M W6R, I13V, K20I, E35D, M36I, R41K, Q61E, L63P, H69K, A71T, T74S, L89ICRF01_AE
 14-013914-0139DQ130504PINA  W6R, I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MCRF01_AE
 14-014714-0147DQ130512PINAN88SL10FW6L, I13V, G17E, K20I, E35N, M36I, R41K, H69K, L89MCRF01_AE
 14-014814-0148DQ130513PINAM46I, I54A, V82A L10I, I13V, G16E, K20I, E35D, M36I, R41K, L63T, I64L, H69K, L89MCRF01_AE
 G586G586DQ130150PINAV82AQ58EW6R, L10I, I13V, G16E, K20I, E35D, M36I, R41K, L63T, H69K, L89MCRF01_AE
 G589G589DQ130152PINA  L10V, I13V, G16A, L19M, K20I, E35N, M36I, N37D, R41K, D60E, Q61E, L63P, H69K, L89M, I93LCRF01_AE
 G614G614DQ130166PINAM46I, I54A, V82A L10I, I13V, G16E, K20I, E35D, M36I, R41K, L63T, I64L, H69K, T74S, L89MCRF01_AE
 G619G619DQ130169PINA  L10I, I13V, G16E, K20I, E35D, M36I, R41K, L63I, H69K, K70R, L89MCRF01_AE
 G626G626DQ130175PINA  I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MCRF01_AE
 G635G635DQ130180PINA  I13V, K20I, E35D, M36I, R41K, H69K, T74S, L89MCRF01_AE
 G658G658DQ130190PINAI54V, V82F, L90ML33I, L89VL10I, I13V, L19I, K20I, E35D, M36I, R41K, H69KCRF01_AE
 G694G694DQ130209PINA  I13V, K20I, E35N, M36I, N37D, R41K, H69K, T74S, L89MCRF01_AE
 G707G707DQ130216PINAI54V, V82T, I84V L10I, I13A, K20I, E35D, M36I, R41K, I66F, H69K, A71V, L89MCRF01_AE
 G724G724DQ130222PINA  I13V, K20I, E35D, M36I, R41K, R57K, H69K, T74S, L89ICRF01_AE
 G734G734DQ130228PINAG48V, I54A, V82A I13V, K20I, E35D, M36I, R41K, I62V, L63P, H69K, K70R, T74S, L89ICRF01_AE
 G742G742DQ130233PINA  L10I, I13V, G16E, K20I, E35D, M36I, R41K, L63H, H69K, K70R, L89M, I93VCRF01_AE
 NP138NP138DQ130253PINAI47V, G48V, I54A, V82A L10I, I13V, G16E, L19P, K20I, E35D, M36I, R41K, H69K, A71V, I72R, L89ICRF01_AE
 NP139NP139DQ130254PINA  I13V, K20I, E35D, M36I, R41K, K55R, I64M, H69K, K70R, L89MCRF01_AE
 NP231NP231DQ130316PINAV82F W6L, L10I, I13V, G16E, K20I, E35D, M36I, R41K, K43R, K45Q, R57K, L63V, H69K, K70R, L89MCRF01_AE
 NP237NP237DQ130321PINAM46I, I54V, L76V, V82FQ58EL10I, I13V, K20I, E35G, M36I, R41K, F53Y, K55R, L63P, H69K, L89MCRF01_AE
 NP249NP249DQ130332PINA  L10I, I13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 NP258NP258DQ130340PINAM46I K20I, E35D, M36I, R41K, H69K, I72V, L89MCRF01_AE
 NP319NP319DQ130397PINA  I13V, K14N, G16E, K20I, E35D, M36I, R41K, K45R, H69K, L89MCRF01_AE
 NP321NP321DQ130399PINAN88SL10FI13V, K20I, E35D, M36I, R41K, I62V, L63P, H69K, T74A, L89M, I93LCRF01_AE
Hsu (2005)BAA154760BAA154760AY870162NFV113  K20I, E35N, M36I, N37D, R41K, L63P, H69K, T74A, L89M, I93LCRF01_AE
 BAA154770BAA154770AY870168IDV52  I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
 BAA157674BAA157674AY870179RTV, IDV22  I13V, G17E, K20I, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
 BAA157679BAA157679AY870184IDV231M46MI, L90M K14R, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89M, I93LCRF01_AE
 BAA161419BAA161419AY870226SQV, RTV  L89MVI13V, K20I, E35D, M36I, R41K, H69K, T74SCRF01_AE
 BAA161449BAA161449AY870242SQV, RTV100G48GMRV, I54V, I84IV, L90MQ58QEL10I, I13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
Non-B Workgroup (2005)TK5004TK5004 SQV, IDV, NFV, RTV, LPV145G48V, I54A, V82A L10I, V11VL, I13V, K14R, I15IV, K20I, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
  TK5004b SQV, IDV, NFV, RTV, LPV162G48V, I54AV, V82AL89IVL10I, V11VL, I13V, K14R, I15IV, K20I, E35D, M36I, R41K, H69K, K70R, A71ATCRF01_AE
Baxter (2006)48-14261426-30225DQ877815PINAG48V, I54A, V82A T4TS, L10I, V11L, I13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
 48-41134113-30319DQ878344PINAI54V, V82A L10I, I13V, G16E, L19I, K20I, E35D, M36I, P39S, R41K, D60DE, I62V, H69K, K70R, A71IV, I72V, T74A, L89ICRF01_AE
Tee (2006)MYKL182204MYKL1822AY960956RTV, IDV M46I, I84VL89VL10I, I13A, K14R, K20I, E35D, M36I, R41K, K55R, I66F, H69K, A71TCRF01_AE
 MYKL195804MYKL1958AY960959RTV, IDV M46I, L76V I13V, K14R, K20I, E35N, M36I, R41K, K55R, R57K, L63P, H69K, K70R, I72V, L89MCRF01_AE
Charpentier (2011)CR-50CR-50FJ688256PINAM46IL10FK20I, E35D, M36I, N37D, R41K, I62IV, L63T, H69K, T74A, V77VI, I85IV, L89M, I93LCRF01_AE
El Annaz (2012)1376113761.PRJN185269IDV52M46I, L76V I13V, K20I, E35D, M36I, N37D, I62IV, L63P, I66F, H69K, L89MCRF01_AE
Nerrienet (2014)U0218166U0218166JN675811LPV   L10I, I13V, G16E, K20I, E35D, M36I, R41K, L63C, H69E, K70R, L89MCRF01_AE
 S1201062S1201062JN675787LPV   T12A, I13V, K20I, E35D, M36I, R41K, L63LP, H69K, K70KR, V82VI, L89MCRF01_AE
 U0316214U0316214JN675765LPV G48V, I54V, V82AL89VT4S, L10I, V11L, I13V, K20I, E35D, M36I, I62IV, L63P, H69K, A71TCRF01_AE
 U0129166U0129166JN675805LPV   I13V, G16E, K20I, E35D, M36I, R41K, R57K, D60E, H69K, K70R, I72IV, L89MCRF01_AE
 R1113090R1113090JN675748LPV M46I, I47V, L76V, I84VL10FI13V, G16Q, L19V, K20I, E35D, M36I, P39S, R41K, K55R, D60E, I66F, H69K, A71AV, L89MCRF01_AE
 S0428149S0428149JN675749LPV M46I, L76V, I84VF53LL10I, I13V, I15V, K20I, E35D, M36I, R41K, K55R, D60E, L63P, I66F, H69K, K70R, L89MCRF01_AE
 S0916071S0916071JN675753LPV M46I, I54V, V82F, L90M L10V, K20I, E35D, M36I, R41K, Q61H, I62V, L63C, H69K, T74S, L89ICRF01_AE
 T0807129T0807129JN675757LPV M46I, I47V, L76V, V82FQ58EL10I, I13V, G16E, K20I, E35DN, M36I, N37ND, K55R, L63T, I64V, H69K, I72T, L89MCRF01_AE
 T0506285T0506285JN675754LPV M46I, I47V, I54V, I84VL10F, L24IK20I, E35N, M36I, K55R, I62V, L63P, H69K, A71V, T74A, L89M, I93LCRF01_AE
 S0822156S0822156JN675752LPV M46L, I47V, G48V, I54V, V82T, I84VF53L, L89VL10I, I13A, K20I, M36I, R41K, L63P, I66F, H69K, A71VCRF01_AE
 U0719200U0719200JN675770LPV M46I, I47A, I84V, L90ML89VL10V, I13A, K20I, M36I, K55R, L63P, H69K, A71V, I93MCRF01_AE
 T0427315T0427315JN675795LPV   I13V, K20I, M36I, N37D, R41K, H69K, L89MCRF01_AE