<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation I13V
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 95
Isolates 108
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG108108_w28 NFV28  L10V, I13V, G16E, K20R, E35D, M36I, R41K, H69K, L89MCRF01_AE
Ariyoshi (2003)JPN42JPN42A SQV104I54V, V82F, L90ML33F, I84LL10V, I13V, I15IV, G16E, K20I, E35D, M36I, N37ND, R41K, H69K, T74S, L89I, Q92KCRF01_AE
  JPN42BAY900686SQV, RTV, APV164I54IV, V82VF, L90LML33I, I84ILL10LV, I13V, G16E, K20KI, E35D, M36I, N37ND, R41K, H69K, T74TS, L89IM, Q92KCRF01_AE
 JPN43JPN43BAY900688NFV67M46MI, L90LML10LFI13V, I15V, K20T, E35D, M36I, R41K, H69K, A71AT, T74TS, L89X, I93ILCRF01_AE
 JPN28JPN28AY900692NFV80M46MI, N88S, L90LML10LFI13V, K20T, E35D, M36I, R41K, H69K, K70R, A71AT, L89XCRF01_AE
 JPN45JPN45A IDV64N88SL10F, L33LI, L89VI13V, K20T, E35D, M36I, R41K, I62IV, L63P, H69K, A71AT, T74TSCRF01_AE
  JPN45BAY900693IDV, APV, LPV68N88SL10F, L89VI13V, K20T, E35D, M36I, P39PS, R41K, L63P, H69K, A71TCRF01_AE
 JPN11JPN11 IDV75  I13V, K20KR, E35D, M36I, R41K, R57K, H69K, L89MCRF01_AE
 JPN12JPN12A SQV77 Q58EI13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
  JPN12BAY900696SQV92 Q58EI13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
 JPN30JPN30 NFV71L90M L10V, I13V, K20T, E35D, M36I, R41K, H69K, K70R, T74S, L89ICRF01_AE
 JPN15JPN15AY900698NFV, IDV113I54V, L90ML10F, L33II13V, K20R, E35D, M36I, R41K, I64V, H69K, L89MCRF01_AE
 JPN31JPN31AY900699SQV, NFV132 L33LI, N83D, L89IVL10LI, I13V, K20KT, A22AV, E35D, M36I, R41K, I62V, H69KCRF01_AE
 JPN32JPN32AY900701NFV116  L10LI, I13V, E35D, M36I, R41K, R57K, H69K, L89MCRF01_AE
 JPN17JPN17A IDV68  I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
  JPN17BAY900702IDV80  I13V, E35D, M36I, R41K, W42WL, K45KE, H69K, L89MCRF01_AE
 JPN34JPN34AY900860IDV, SQV76G48V, I54IVL33LF, N83NDL10LI, I13V, I15V, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
 JPN35JPN35AY900862IDV, NFV140M46I, L90M L10V, I13V, K20T, E35D, M36I, R41K, Q61H, L63P, I64V, H69K, K70R, T74S, R87X, L89M, I93LCRF01_AE
 JPN37JPN37A IDV45  I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
  JPN37BAY900864IDV, SQV, RTV128  I13V, E35D, M36I, R41K, H69K, I72IV, L89MCRF01_AE
 JPN38JPN38 IDV, NFV129I54V, V82F L10I, I13V, G16E, K20I, E35D, M36I, R41K, K45V, L63LH, H69K, K70R, L89M, F99FLCRF01_AE
 JPN39JPN39AY900865NFV200M46I, N88SL10FI13V, K20I, E35D, M36I, R41RK, I64V, H69K, T74S, V77VI, L89M, I93LCRF01_AE
 JPN3JPN3 IDV56V82VF L10I, I13V, I15V, E35D, M36I, R41K, R57K, H69K, L89MCRF01_AE
 JPN6JPN6 NFV1 L24LII13V, I15V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 JPN7JPN7AY900867NFV7  L10I, I13V, E35D, M36I, G40GR, R41K, H69K, I72V, L89MCRF01_AE
 JPN22JPN22 NFV1  I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 JPN40JPN40A IDV, SQV, NFV179 L10FT12A, I13V, I15V, E35D, M36I, R41K, R57K, I64V, H69K, L89MCRF01_AE
  JPN40BAY900871IDV, SQV, NFV218 L10LFT12A, I13V, I15IV, E35D, M36I, R41K, R57K, I64IV, H69K, L89MCRF01_AE
 JPN41JPN41A IDV, SQV, NFV125G48ST, I54V, V82F, L90M L10I, I13V, G16E, K20I, E35D, M36I, P39Q, R41K, K45V, I62V, L63P, H69K, L89MCRF01_AE
  JPN41BAY900873IDV, SQV, NFV, APV195I54V, V82F, L90LM L10I, I13V, G16E, K20I, E35DN, M36I, P39Q, R41K, K45V, G48X, I62V, L63P, H69K, L89MCRF01_AE
 JPN25JPN25AY900874NFV73M46I, N88SL10F, L33I, Q58QE, L89VI13V, K20T, E35D, M36I, R41K, I62IV, H69KCRF01_AE
Montes (2004)MB_patMOU00_MOUL723AJ577956SQV160  I13V, K14R, G17E, K20I, M36I, R41K, L63T, I64M, H69K, T74A, L89MCRF01_AE
 MB_patBRI00_BRI706AJ577745SQV, NFV, RTV111  Q7P, I13V, I15V, K20R, E35D, M36I, N37D, R41K, R57K, H69K, T74S, L89MCRF01_AE
  01_BRI705AJ577746SQV, NFV, RTV, LPV146I54V, V82AL33F, F53L, T74PL10I, I13V, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, H69K, K70R, L89MCRF01_AE
 MB_patPOI01_POI735AJ577975SQV, NFV, RTV160  I13V, E35D, M36I, N37D, R41K, L63P, H69K, K70R, L89MCRF01_AE
 MB_patCAL00_CAL703AJ577857SQV, IDV, RTV98I84V I13V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89TCRF01_AE
Nukoolkarn (2004)7474 RTV I54V, V82AL33F, N83DL10I, I13V, E35D, M36I, R41K, D60E, Q61D, L63T, C67Y, H69K, L89MCRF01_AE
 220220 RTV, IDV I54V, V82AG48I, F53L, L89VL10I, I13V, K20I, E35D, M36I, N37D, R41K, L63P, H69K, A71VCRF01_AE
 238238 LPV L90M L10I, I13V, E35D, M36I, R41K, L63P, H69K, T74S, L89MCRF01_AE
 245245 SQV, RTV, IDV I54V, V82FL33IL10I, I13V, E35D, M36I, R41K, L63H, H69K, L89MCRF01_AE
 276276 RTV, IDV   I13V, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
 321321 NFV L90M I13V, K20I, E35D, M36I, R41K, I64V, H69K, L89MCRF01_AE
Hsu (2005)BAA148356BAA148356AY870142IDV, NFV134N88S I13V, E35D, M36I, R41K, I64IV, H69K, L89MCRF01_AE
 BAA148357BAA148357AY870143IDV, SQV, RTV65  I13V, I15V, E35D, M36I, R41K, L63V, H69K, L89M, I93LCRF01_AE
 BAA148358BAA148358AY870144SQV, RTV52  I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BAA148363BAA148363AY870148SQV, RTV35I84V, L90M L10V, I13V, K20R, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
 BAA148375BAA148375AY870150SQV, RTV4  I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BAA150607BAA150607AY870152SQV, RTV78M46ML, G48V, I84IV, L90LML89VI13V, E35D, M36I, R41K, H69KCRF01_AE
 BAA150624BAA150624AY870158SQV, RTV31G48V, I84VL33F, Q58E, N83DL10V, I13V, K14KN, K20R, E35D, M36I, R41K, L63LP, H69K, L89ICRF01_AE
 BAA150627BAA150627AY870159SQV, RTV61G48V, I54IV, V82AL33F, F53L, N83DL10I, I13V, M36L, R41K, I62IV, L63P, H69K, T74S, L89IM, I93IVCRF01_AE
 BAA154758BAA154758AY870160IDV152  T12P, I13V, G16E, E35D, M36I, N37D, L63H, H69K, L89MCRF01_AE
 BAA154762BAA154762AY870163SQV, RTV113  I13V, I15IV, E35D, M36I, R41K, H69K, K70KR, L89MCRF01_AE
 BAA154770BAA154770AY870168IDV52  I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
 BAA154777BAA154777AY870169SQV, NFV182  I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BAA157674BAA157674AY870179RTV, IDV22  I13V, G17E, K20I, E35D, M36I, R41K, L63S, H69K, L89MCRF01_AE
 BAA157675BAA157675AY870180RTV, IDV4  I13V, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
 BAA157678BAA157678AY870183SQV, RTV131G48VL33F, N83DI13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BAA157683BAA157683AY870187SQV, RTV22  I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BAA161416BAA161416AY870225IDV309  I13V, G16GE, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BAA161419BAA161419AY870226SQV, RTV  L89MVI13V, K20I, E35D, M36I, R41K, H69K, T74SCRF01_AE
 BAA161422BAA161422AY870228IDV317M46ML, I54IV, V82F L10LI, I13V, K20KI, E35D, M36I, R41K, I62V, H69K, T74A, L89MCRF01_AE
 BAA161424BAA161424AY870229IDV91 L89MVI13V, K20KI, E35D, M36I, R41K, I62V, H69K, K70R, T74ACRF01_AE
 BAA161428BAA161428AY870230IDV39 L33FI13V, E35D, M36I, R41K, H69K, L89M, I93VCRF01_AE
 BAA161430BAA161430AY870232IDV, SQV88G48V, I54V, V82AF53LL10I, I13V, L19LV, K20R, E35D, M36I, N37D, R41K, I62V, L63LP, H69K, A71T, T74S, L89ICRF01_AE
 BAA161433BAA161433AY870233IDV, SQV, RTV270G48V, L90ML33F, N83DL10I, I13V, E35D, M36I, R41K, L63T, H69K, L89IMCRF01_AE
 BAA161436BAA161436AY870234SQV, RTV26 L33FL10I, I13V, R41K, I62V, L63I, H69K, K70R, V82I, L89MCRF01_AE
 BAA161439BAA161439AY870235NFV252I84IVL10F, L89VI13V, K20T, E35D, M36I, R41K, H69K, A71T, T74SCRF01_AE
 BAA161445BAA161445AY870238SQV, RTV61  I13V, G16E, E35D, M36I, R41K, H69K, K70R, L89MCRF01_AE
 BAA161449BAA161449AY870242SQV, RTV100G48GMRV, I54V, I84IV, L90MQ58QEL10I, I13V, G16E, K20I, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BAA161450BAA161450AY870243SQV, RTV148  I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 BAA161452BAA161452AY870245SQV, RTV70  I13V, E35D, M36I, R41K, I62V, H69K, T74S, L89MCRF01_AE
Non-B Workgroup (2005)TH_130TH_130AY605552RTV, IDV   I13V, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
 TH_160TH_160AY605572RTV, IDV   I13V, E35D, M36I, R41K, R57K, H69K, L89MCRF01_AE
 TH_161TH_161AY605574SQV, RTV   I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 TH_215TH_215AY605617NFV N88S, L90ML10FI13V, I15V, K20T, E35D, M36I, R41K, I64V, H69K, L89MCRF01_AE
 TH_220TH_220AY605624IDV   L10I, I13V, G16E, K20R, E35D, M36I, R41K, I62V, H69K, L89M, L97ICRF01_AE
 TH_223TH_223AY605628IDV   L10I, I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 TK1018TK1018 RTV, SQV, IDV184I84VL33F, N83DL10V, I13V, E34Q, M36I, N37S, R41K, L63P, H69K, L89M, I93LCRF01_AE
 TK1029TK1029 IDV172  I13V, L19M, E35D, M36I, R41K, H69K, L89MCRF01_AE
 TK3028TK3028 SQV, NFV115 L89VI13V, E35D, M36I, R41K, H69K, A71ATCRF01_AE
  TK3028a SQV, NFV186 L89VI13V, K20T, E35D, M36I, N37NY, R41K, H69K, A71TCRF01_AE
 TK4002TK4002 IDV, RTV145  I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 TK5004TK5004 SQV, IDV, NFV, RTV, LPV145G48V, I54A, V82A L10I, V11VL, I13V, K14R, I15IV, K20I, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
  TK5004a SQV, IDV, NFV, RTV, LPV151  I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
  TK5004b SQV, IDV, NFV, RTV, LPV162G48V, I54AV, V82AL89IVL10I, V11VL, I13V, K14R, I15IV, K20I, E35D, M36I, R41K, H69K, K70R, A71ATCRF01_AE
Baxter (2006)48-14261426-30225DQ877815PINAG48V, I54A, V82A T4TS, L10I, V11L, I13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, K70R, L89ICRF01_AE
 48-30333033-30227DQ877944PINAG48Q, I50V, I54A, V82MK43T, F53LL10I, I13V, G16E, L19R, K20I, E35D, M36I, R41K, Q61D, L63C, I66F, H69K, L89MCRF01_AE
 48-41134113-30319DQ878344PINAI54V, V82A L10I, I13V, G16E, L19I, K20I, E35D, M36I, P39S, R41K, D60DE, I62V, H69K, K70R, A71IV, I72V, T74A, L89ICRF01_AE
Tee (2006)MYKL136403MYKL1364AY960927RTV, IDV   I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 MYKL136803MYKL1368AY960928RTV, IDV61  I13V, G16E, E35D, M36I, R41K, H69K, L89MCRF01_AE
 MYKL140903MYKL1409AY960934PINAM46I I13V, M36I, R41K, H69K, L89MCRF01_AE
 MYKL151003MYKL1510AY960941IDV22  I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 MYKL162304MYKL1623AY960947RTV, IDV200  I13V, E35D, M36I, R41K, H69KCRF01_AE
 MYKL174304MYKL1743AY960952RTV, IDV V82F I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 MYKL177904MYKL1779AY960953LPV   I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 MYKL194904MYKL1949AY960958IDV65  L10V, I13V, G16A, E35D, M36I, R41K, H69K, L89MCRF01_AE
 MYKL195804MYKL1958AY960959RTV, IDV M46I, L76V I13V, K14R, K20I, E35N, M36I, R41K, K55R, R57K, L63P, H69K, K70R, I72V, L89MCRF01_AE
von Wyl (2007)345869337EF449787PINAI54VN83DL10I, I13V, G16A, A22V, E35D, M36I, R41K, L63V, H69K, L89ICRF01_AE
 461798027EF449810PINA  I13V, G16E, E35D, M36I, R41K, H69K, A71AV, L89M, Q92KCRF01_AE
 791477616EF449916PINA  I13V, E35D, M36I, R41K, R57K, H69K, L89MCRF01_AE
Rosen-Zvi (2008)1602p16-1 SQV, RTV, IDV47  L10I, T12A, I13V, E35D, M36I, R41K, R57K, L63LAPV, H69K, K70KR, L89MCRF01_AE
  06p16-2 SQV, RTV, IDV, LPV287V82F L10I, T12A, I13V, E35D, M36I, R41K, R57K, H69K, L89ICRF01_AE
 8207p82-2 LPV92  I13V, I15V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 8309p83-4 LPV63  L10V, I13V, G16GE, E35D, M36I, N37D, R41K, L63PS, H69K, K70R, L89MCRF01_AE
Charpentier (2011)4CP 001-045 Unknown, IDVNAL90ML33IL10V, I13V, L19F, K20T, E35D, M36I, R41K, R57K, L63P, H69K, T74S, L89ICRF01_AE
Ferradini (2011) 0739PRHM026302LPV24V82A L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63C, H69K, T74A, L89MCRF01_AE
 50789PRHM026303FPV, LPV24M46I, L76V, I84VL10FI13V, G16E, E21K, E35D, M36I, R41K, H69K, I72R, L89ICRF01_AE
Barber (2012)7740677406JQ361675LPV M46IL10F, T74TPI13V, I15IV, E35D, M36I, R41K, L63C, H69K, N83S, L89MCRF01_AE

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