<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L10V
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 22
Isolates 24
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG108108_w28 NFV28  L10V, I13V, G16E, K20R, E35D, M36I, R41K, H69K, L89MCRF01_AE
Ariyoshi (2003)JPN42JPN42A SQV104I54V, V82F, L90ML33F, I84LL10V, I13V, I15IV, G16E, K20I, E35D, M36I, N37ND, R41K, H69K, T74S, L89I, Q92KCRF01_AE
 JPN30JPN30 NFV71L90M L10V, I13V, K20T, E35D, M36I, R41K, H69K, K70R, T74S, L89ICRF01_AE
 JPN35JPN35AY900862IDV, NFV140M46I, L90M L10V, I13V, K20T, E35D, M36I, R41K, Q61H, L63P, I64V, H69K, K70R, T74S, R87X, L89M, I93LCRF01_AE
Hsu (2005)BAA148363BAA148363AY870148SQV, RTV35I84V, L90M L10V, I13V, K20R, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
 BAA150624BAA150624AY870158SQV, RTV31G48V, I84VL33F, Q58E, N83DL10V, I13V, K14KN, K20R, E35D, M36I, R41K, L63LP, H69K, L89ICRF01_AE
 BAA161429BAA161429AY870231RTV, IDV78  L10V, K20R, E35D, M36I, R41K, H69K, I72V, L89MCRF01_AE
Non-B Workgroup (2005)TK1018TK1018 RTV, SQV, IDV184I84VL33F, N83DL10V, I13V, E34Q, M36I, N37S, R41K, L63P, H69K, L89M, I93LCRF01_AE
Baxter (2006)48-41434143-30408DQ878375PINAG48V, I54A, V82S L10V, I15V, L19I, K20R, E35D, M36I, R41K, I62V, L63V, H69K, T74S, L89M, I93LCRF01_AE
Tee (2006)MYKL194904MYKL1949AY960958IDV65  L10V, I13V, G16A, E35D, M36I, R41K, H69K, L89MCRF01_AE
Rosen-Zvi (2008)3606p36-2 LPV155  L10V, T12I, I13A, I15V, G16E, E35D, M36I, R41K, K45R, L63T, H69K, L89MCRF01_AE
  06p36-3 LPV155  L10V, T12I, I13AV, I15IV, G16E, E35D, M36I, R41K, K45R, L63T, H69K, I72IV, L89MCRF01_AE
 8309p83-4 LPV63  L10V, I13V, G16GE, E35D, M36I, N37D, R41K, L63PS, H69K, K70R, L89MCRF01_AE
Charpentier (2011)4CP 001-045 Unknown, IDVNAL90ML33IL10V, I13V, L19F, K20T, E35D, M36I, R41K, R57K, L63P, H69K, T74S, L89ICRF01_AE
Ferradini (2011) 0739PRHM026302LPV24V82A L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63C, H69K, T74A, L89MCRF01_AE
Rawizza (2013)LL0499LL0499KF241476LPV M46L, G48V, L90ML33F, N83DL10V, I13V, K20R, E35DN, M36I, N37E, P39Q, R41K, D60E, Q61E, H69K, L89IMCRF01_AE
Nerrienet (2014)T1005142T1005142JN675761LPV M46I, I54V, V82A, L90M L10V, G16E, K20R, E35D, M36V, P39S, R41K, K55R, I62V, L63P, H69K, A71V, I93LCRF01_AE
 U0401148U0401148JN675808LPV   L10V, E35D, M36I, R41K, R57K, I62IV, L63C, H69K, T74S, L89MCRF01_AE
 S0916071S0916071JN675753LPV M46I, I54V, V82F, L90M L10V, K20I, E35D, M36I, R41K, Q61H, I62V, L63C, H69K, T74S, L89ICRF01_AE
 S0613189S0613189JN675750LPV V82A L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63C, H69K, T74A, L89MCRF01_AE
 U0527075U0527075JN675769LPV M46I, I47V, L76V, I84VL33I, F53L, Q58E, L89VL10V, I13A, G16E, K20I, E35D, M36I, N37H, P39S, R41K, K55R, D60E, Q61H, I62V, I66F, H69K, K70R, A71VCRF01_AE
 U0907156U0907156JN675771LPV V32I, M46I, I47V, I54M, L90ML33F, Q58E, N83DL10V, I13V, G16A, M36I, N37D, R41K, K55R, D60N, L63P, I64V, H69K, K70R, A71IV, G73GD, L89ICRF01_AE
 T0910001T0910001JN675759LPV M46I L10V, I13V, G16E, K20T, M36I, G40R, R41K, H69K, L89MCRF01_AE
 U0719200U0719200JN675770LPV M46I, I47A, I84V, L90ML89VL10V, I13A, K20I, M36I, K55R, L63P, H69K, A71V, I93MCRF01_AE