<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L10V
Rx >= 1 PI
IncludeMixtures No
References 14
Patients 67
Isolates 68
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Chantratita (2002)GEN19GEN19AF191202PINAG48VL33F, F53L, N83DL10V, I13V, G16E, K20R, E35D, M36I, P39S, R41K, H69K, K70R, T74S, L89MCRF01_AE
 GEN15GEN15AF191199PINAM46I, L90MT74PL10V, K20R, E35D, M36I, R41K, K55R, I62V, L63P, H69K, L89MCRF01_AE
 G30G30AF193896PINA  L10V, I13V, G16A, E35D, M36I, R41K, R57K, H69K, L89M, T91ACRF01_AE
 G73G73AF240396PINAM46L, I84VL33I, N83DL10V, I13V, A22V, E35D, M36I, R41K, H69K, T74S, L89ICRF01_AE
 G53G53AF240380PINA  L5F, L10V, I13V, I15V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 G50G50AF240377PINA  L10V, I13V, G16E, K20R, E35D, M36I, R41K, I62V, H69K, L89MCRF01_AE
Gibb (2002)DMG108108_w28 NFV28  L10V, I13V, G16E, K20R, E35D, M36I, R41K, H69K, L89MCRF01_AE
Ariyoshi (2003)JPN42JPN42A SQV104I54V, V82F, L90ML33F, I84LL10V, I13V, I15IV, G16E, K20I, E35D, M36I, N37ND, R41K, H69K, T74S, L89I, Q92KCRF01_AE
 JPN30JPN30 NFV71L90M L10V, I13V, K20T, E35D, M36I, R41K, H69K, K70R, T74S, L89ICRF01_AE
 JPN35JPN35AY900862IDV, NFV140M46I, L90M L10V, I13V, K20T, E35D, M36I, R41K, Q61H, L63P, I64V, H69K, K70R, T74S, R87X, L89M, I93LCRF01_AE
Chantratita (2005)14-004214-0042DQ130443PINA  L10V, I15V, E35D, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
 14-004614-0046DQ130445PINA  L10V, V11L, I13V, G16E, E35D, M36I, N37H, R41K, H69K, K70R, I72V, V82I, L89MCRF01_AE
 14-006814-0068DQ130454PINA  W6R, L10V, I13V, G16E, E35D, M36I, R41K, K43R, L63S, H69K, L89MCRF01_AE
 14-006914-0069DQ130455PINA  L10V, I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 14-007114-0071DQ130457PINA  W6R, L10V, G16E, K20R, E35D, M36I, R41K, D60E, I62V, L63P, H69K, L89M, I93LCRF01_AE
 14-008414-0084DQ130460PINAI54A L10V, I13V, K20V, E35N, M36I, R41K, I62V, L63P, H69K, A71L, T74SCRF01_AE
 14-013314-0133DQ130498PINA  L10V, I13V, G16E, M36I, R41K, H69K, L89MCRF01_AE
 14-014014-0140DQ130505PINA  W6R, L10V, I13V, G16E, E35D, M36I, R41K, H69K, L89MCRF01_AE
 G527G527DQ130118PINA  L10V, I13V, K20R, E35D, M36I, R41K, H69K, L89MCRF01_AE
 G529G529DQ130119PINA  L10V, I13V, G16E, E35D, M36I, R41K, H69K, I72V, L89MCRF01_AE
 G563G563DQ130136PINAD30N, M46IN88DW6R, L10V, K20R, E35D, M36I, R41K, L63P, H69K, V77I, I93LCRF01_AE
 G589G589DQ130152PINA  L10V, I13V, G16A, L19M, K20I, E35N, M36I, N37D, R41K, D60E, Q61E, L63P, H69K, L89M, I93LCRF01_AE
 G590G590DQ130153PINAI54V L10V, I13V, K20V, E35N, M36I, R41K, I62V, L63P, H69K, A71L, T74SCRF01_AE
 G605G605DQ130161PINAI54V, V82AL33F, Q58E, N83DL10V, I13V, E35D, M36I, R41K, H69K, L89ICRF01_AE
 G606G606DQ130162PINA  L10V, E35D, M36I, R41K, H69K, K70R, L89MCRF01_AE
 G613G613DQ130165PINA  L10V, E35D, M36I, N37D, R41K, H69K, L89MCRF01_AE
 G652G652DQ130187PINA  L10V, I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 G713G713DQ130219PINAV82AL33F, N83DL10V, I13V, I15V, E35D, M36I, R41K, H69K, L89MCRF01_AE
 G741G741DQ130232PINA  L10V, I13V, M36I, R41K, L63P, H69K, V82I, L89MCRF01_AE
 G748G748DQ130235PINA  L10V, I13V, I15V, E35D, M36I, R41K, L63P, H69K, L89M, I93LCRF01_AE
 NP145NP145DQ130259PINA  L10V, I13V, G16E, K20R, E35D, M36I, P39S, R41K, H69K, K70R, T74S, L89MCRF01_AE
 NP164NP164DQ130268PINAM46IL33I, N83DL10V, I13V, K14N, G16A, K20T, A22V, E35D, M36I, R41K, I62V, L63V, H69K, K70R, T74S, V82I, L89I, I93LCRF01_AE
 NP170NP170DQ130274PINA  L10V, G16E, K20R, E35D, M36I, R41K, H69K, I72V, L89M, I93LCRF01_AE
 NP174NP174DQ130278PINA  L10V, I13V, K20T, E35D, M36I, N37D, R41K, D60E, H69K, A71T, T74S, L89ICRF01_AE
 NP176NP176DQ130280PINA  L10V, T12A, I13V, K14R, G16E, E35D, M36I, R41K, H69K, L89MCRF01_AE
 NP179NP179DQ130283PINA  L10V, I13V, G16E, E35D, M36I, R41K, R57K, H69K, K70R, L89MCRF01_AE
 NP191NP191DQ130295PINA  L10V, I13V, E35D, M36I, R41K, H69K, V82I, L89MCRF01_AE
 NP193NP193DQ130297PINA  L10V, I13V, K14R, G16E, E35D, M36I, R41K, H69K, L89MCRF01_AE
 NP226NP226DQ130311PINA  L10V, T12A, I13V, K14R, G16E, E35D, M36I, R41K, H69K, L89MCRF01_AE
 NP234NP234DQ130319PINAI84V L10V, I13V, K20R, E35D, M36I, R41K, R57K, I62V, L63P, H69K, T74A, L89ICRF01_AE
 NP264NP264DQ130346PINA  W6R, L10V, I13V, I15V, E35D, M36I, N37D, R41K, H69K, L89MCRF01_AE
 NP271NP271DQ130353PINA  L10V, I13V, K20R, E35D, M36I, N37D, R41K, K43R, D60E, Q61E, H69K, L89MCRF01_AE
 NP282NP282DQ130363PINA  W6R, L10V, I13V, E35D, M36I, R41K, H69K, K70R, L89MCRF01_AE
 NP293NP293DQ130373PINAG48M, I54V, V82AF53L, N83DL10V, I13V, G16E, K20R, A22V, E35D, M36I, P39S, R41K, I62V, L63H, H69K, I72V, L89I, T91SCRF01_AE
 NP305NP305DQ130385PINA  W6G, L10V, I13V, K14R, E35D, M36I, R41K, H69K, L89MCRF01_AE
 NP313NP313DQ130391PINA  L10V, I13V, K14N, G16E, K20R, E35D, M36I, R41K, K43R, L63T, H69K, K70R, L89MCRF01_AE
Hsu (2005)BAA148363BAA148363AY870148SQV, RTV35I84V, L90M L10V, I13V, K20R, E35D, M36I, R41K, L63P, H69K, L89MCRF01_AE
 BAA150624BAA150624AY870158SQV, RTV31G48V, I84VL33F, Q58E, N83DL10V, I13V, K14KN, K20R, E35D, M36I, R41K, L63LP, H69K, L89ICRF01_AE
 BAA161429BAA161429AY870231RTV, IDV78  L10V, K20R, E35D, M36I, R41K, H69K, I72V, L89MCRF01_AE
Non-B Workgroup (2005)TK1018TK1018 RTV, SQV, IDV184I84VL33F, N83DL10V, I13V, E34Q, M36I, N37S, R41K, L63P, H69K, L89M, I93LCRF01_AE
Tee (2006)MYKL194904MYKL1949AY960958IDV65  L10V, I13V, G16A, E35D, M36I, R41K, H69K, L89MCRF01_AE
von Wyl (2007)85495945EF449807PINA  L10V, I13V, E35D, M36I, R41K, H69K, L89MCRF01_AE
Rosen-Zvi (2008)3606p36-2 LPV155  L10V, T12I, I13A, I15V, G16E, E35D, M36I, R41K, K45R, L63T, H69K, L89MCRF01_AE
  06p36-3 LPV155  L10V, T12I, I13AV, I15IV, G16E, E35D, M36I, R41K, K45R, L63T, H69K, I72IV, L89MCRF01_AE
 8309p83-4 LPV63  L10V, I13V, G16GE, E35D, M36I, N37D, R41K, L63PS, H69K, K70R, L89MCRF01_AE
Ferradini (2011)40739PRHM026302LPV24V82A L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63C, H69K, T74A, L89MCRF01_AE
Rawizza (2013)LL0499LL0499KF241476LPV M46L, G48V, L90ML33F, N83DL10V, I13V, K20R, E35DN, M36I, N37E, P39Q, R41K, D60E, Q61E, H69K, L89IMCRF01_AE
Nerrienet (2014)T1005142T1005142JN675761LPV M46I, I54V, V82A, L90M L10V, G16E, K20R, E35D, M36V, P39S, R41K, K55R, I62V, L63P, H69K, A71V, I93LCRF01_AE
 U0401148U0401148JN675808LPV   L10V, E35D, M36I, R41K, R57K, I62IV, L63C, H69K, T74S, L89MCRF01_AE
 S0916071S0916071JN675753LPV M46I, I54V, V82F, L90M L10V, K20I, E35D, M36I, R41K, Q61H, I62V, L63C, H69K, T74S, L89ICRF01_AE
 S0613189S0613189JN675750LPV V82A L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63C, H69K, T74A, L89MCRF01_AE
 T0910001T0910001JN675759LPV M46I L10V, I13V, G16E, K20T, M36I, G40R, R41K, H69K, L89MCRF01_AE
 U0719200U0719200JN675770LPV M46I, I47A, I84V, L90ML89VL10V, I13A, K20I, M36I, K55R, L63P, H69K, A71V, I93MCRF01_AE
Jenabian (2015)DR46DR46KF735849PINA  L10V, K14R, I15IV, G16GE, L19I, E35X, M36I, N37D, R41RK, K45R, R57RK, L63T, H69K, K70KR, L89XCRF01_AE
Zain (2015)MYHIVDR129MYHIVDR129KT281524PINA  L10V, I13V, K20R, E35D, M36I, R41K, H69K, V77I, L89MCRF01_AE
 MYHIVDR043MYHIVDR043KT281514PINA  L10V, I13V, I15V, G16E, E35D, M36I, R41K, H69K, I72IV, L89MCRF01_AE
 MYHIVDR016MYHIVDR016KT281507PINA  L10V, I13V, G16E, E35D, M36I, R41K, R57K, H69K, L89MCRF01_AE
 MYHIVDR083MYHIVDR083KT281499PINA  L10V, I13V, G16E, E35D, M36I, R41K, H69K, K70R, I72V, L89MCRF01_AE