<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF01_AE
Gene PR
Mutation L10F
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 22
Isolates 25
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Ariyoshi (2003)JPN45JPN45A IDV64N88SL10F, L33LI, L89VI13V, K20T, E35D, M36I, R41K, I62IV, L63P, H69K, A71AT, T74TSCRF01_AE
  JPN45BAY900693IDV, APV, LPV68N88SL10F, L89VI13V, K20T, E35D, M36I, P39PS, R41K, L63P, H69K, A71TCRF01_AE
 JPN15JPN15AY900698NFV, IDV113I54V, L90ML10F, L33II13V, K20R, E35D, M36I, R41K, I64V, H69K, L89MCRF01_AE
 JPN19JPN19A NFV59N88SL10FG16E, K20IT, E35D, M36I, R41K, L63T, I64V, H69K, L89M, I93LCRF01_AE
  JPN19BAY900861NFV77N88SL10FG16E, K20I, E35D, M36I, R41K, L63T, I64V, H69K, L89M, I93LCRF01_AE
 JPN39JPN39AY900865NFV200M46I, N88SL10FI13V, K20I, E35D, M36I, R41RK, I64V, H69K, T74S, V77VI, L89M, I93LCRF01_AE
 JPN21JPN21A IDV, NFV124M46I, N88SL10F, T74TP, L89VK20I, M36I, L63LP, H69K, I85V, I93LCRF01_AE
  JPN21BAY900869IDV, NFV132M46I, N88SL10F, L89VK20I, M36I, H69K, I85V, I93LCRF01_AE
 JPN40JPN40A IDV, SQV, NFV179 L10FT12A, I13V, I15V, E35D, M36I, R41K, R57K, I64V, H69K, L89MCRF01_AE
 JPN25JPN25AY900874NFV73M46I, N88SL10F, L33I, Q58QE, L89VI13V, K20T, E35D, M36I, R41K, I62IV, H69KCRF01_AE
Hsu (2005)BAA161439BAA161439AY870235NFV252I84IVL10F, L89VI13V, K20T, E35D, M36I, R41K, H69K, A71T, T74SCRF01_AE
Non-B Workgroup (2005)TH_215TH_215AY605617NFV N88S, L90ML10FI13V, I15V, K20T, E35D, M36I, R41K, I64V, H69K, L89MCRF01_AE
Ferradini (2011)50789PRHM026303APV, LPV24M46I, L76V, I84VL10FI13V, G16E, E21K, E35D, M36I, R41K, H69K, I72R, L89ICRF01_AE
Barber (2012)7740677406JQ361675LPV M46IL10F, T74TPI13V, I15IV, E35D, M36I, R41K, L63C, H69K, N83S, L89MCRF01_AE
Nerrienet (2014)S0815116S0815116JN675751LPV V32I, I47AL10FI13V, M36I, R41K, H69K, L89ICRF01_AE
 T0826079T0826079JN675758LPV M46I, I47A, I84V, L90ML10F, L33I, F53LI13V, G16A, L19I, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, C67F, H69K, K70R, L89I, T91VCRF01_AE
 T1022129T1022129JN675762LPV M46L, I54V, I84VL10F, V11I, L33I, Q58E, N83D, L89VT4P, I13V, K14R, K20R, A22V, E35S, M36I, R41K, D60E, I62V, L63P, H69K, A71V, T91G, Q92ECRF01_AE
 U0407179U0407179JN675767LPV M46I, I84V, L90ML10F, L33F, F53L, Q58E, G73GS, N88G, L89VI13V, K20T, E35D, M36I, R41K, K55R, R57K, L63P, I66IF, H69K, A71VCRF01_AE
 R1113090R1113090JN675748LPV M46I, I47V, L76V, I84VL10FI13V, G16Q, L19V, K20I, E35D, M36I, P39S, R41K, K55R, D60E, I66F, H69K, A71AV, L89MCRF01_AE
 U0223070U0223070JN675763LPV I54V, V82A, L90ML10F, K43KT, L89VI13V, G16E, K20I, E35D, M36I, N37D, R41K, Q61H, L63R, H69K, A71T, T91SCRF01_AE
 T0929127T0929127JN675760LPV I54V, V82AL10FT12P, I13V, G16E, K20R, E35D, M36I, R41K, K45I, L63T, H69K, L89MCRF01_AE
 R0130090R0130090JN675745LPV M46I, L76V, I84VL10FI13V, G16E, E21K, E35D, M36I, R41K, H69K, I72R, L89ICRF01_AE
 R0606212R0606212JN675746LPV I54V, V82AL10F, N83DI13V, K20R, A22V, M36I, N37D, R41K, L63LP, H69K, L89I, T91ACRF01_AE
 T0506285T0506285JN675754LPV M46I, I47V, I54V, I84VL10F, L24IK20I, E35N, M36I, K55R, I62V, L63P, H69K, A71V, T74A, L89M, I93LCRF01_AE
 T0518207T0518207JN675755LPV M46MI, I54V, V82AL10F, L33LI, Q58EI13V, E35D, M36I, H69K, K70R, L89ICRF01_AE