<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L89T
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 21
Isolates 21
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Grossman (2004)IL201IL201cAY529566IDV83  L10I, T12S, I15V, L19T, M36I, L63P, I64L, H69K, L89T, I93LC
Snoeck (2004)BE13bBE13bAY900730IDV44M46IL24IT12S, I15V, L19I, M36I, N37K, R41N, K45R, L63P, H69K, L89T, I93LC
Non-B Workgroup (2005)UK1147UK1147AY900794IDV, NFV117M46IK43TT12S, I15V, L19I, K20T, E35D, M36I, N37D, D60E, Q61E, L63P, H69K, A71T, L89T, I93LC
Diaz (2015)RenG16729RenG16729KT747757PINAM46I I13V, I15V, K20R, E35D, M36I, N37K, R41N, K55R, R57K, L63P, H69K, K70KR, A71AT, L89T, I93LC
 RenG17238RenG17238KT748266PINA  I15V, K20I, E35G, M36I, N37K, R41N, K45R, H69K, A71V, T74S, I85V, L89T, I93LC
 RenG16715RenG16715KT747743PINAD30N, I54LN88DL10Y, I15V, L19Q, K20T, E35D, M36I, N37K, R41N, L63V, H69K, A71T, L89T, I93LC
 RenG13693RenG13693KT744721PINA  I15V, E34D, E35D, M36I, N37K, R41N, K45R, I62V, L63P, H69Q, L89T, I93LPC
 RenG13882RenG13882KT744910PINAL90M L10I, V11F, I15V, L19I, K20I, L33V, R41K, K45R, L63P, H69K, A71I, L89T, I93LC
 RenG15162RenG15162KT746190PINA L23II13IV, K20KR, E35D, M36MIV, N37K, R41N, K45R, L63P, H69K, A71IV, L89T, I93LC
 RenG13568RenG13568KT744596PINAM46I, I54V, V82AK43T, T74PL10Y, I15V, L19LI, K20R, E35D, M36I, N37K, R41N, Q61N, I62IV, L63P, H69K, L89T, I93LC
 RenG11998RenG11998KT743026PINAI50L I15V, G16A, K20R, E35D, M36I, N37K, R41N, K45R, L63P, H69K, A71T, V82VI, L89T, I93LC
 RenG12082RenG12082KT743110PINAM46I, I50V, V82A, L90ML10F, V11VI, L23I, L33F, Q58EI13V, I15V, K20R, E35D, M36I, N37K, R41N, L63P, H69K, G73V, T74S, L89T, I93LC
 RenG12731RenG12731KT743759PINA  I15V, K20T, E35D, M36I, N37NK, R41N, K45R, L63C, H69K, A71V, T74TS, L89T, I93LC
 RenG11780RenG11780KT742808PINAI54IV L10Y, I15V, K20I, E35G, M36I, N37K, R41N, K45R, H69K, A71I, T74S, I85V, L89T, I93LC
 RenG10356RenG10356KT741384PINA L23II13V, I15V, K20R, E35D, M36I, N37K, R41N, K45R, R57K, L63P, H69K, T74S, L89T, I93LC
 RenG10972RenG10972KT742000PINAM46I I15V, E35D, M36I, N37K, R41N, L63P, H69K, T74S, L89T, I93LC
 RenG10990RenG10990KT742018PINAI84V L10Y, I13IV, I15V, K20R, E35D, M36I, N37K, R41N, L63P, H69K, A71IV, I85IV, L89T, I93LC
 RenG10952RenG10952KT741980PINA L23II13V, I15V, K20R, E35D, M36I, N37K, R41N, K45R, Q61H, L63P, H69K, A71T, L89T, I93LC
 RenG11404RenG11404KT742432PINAM46I, I54V, V82AV11I, L24I, L33FL10V, I13V, I15V, K20R, E35D, M36I, N37NK, R41P, K45KR, I62V, L63Q, G68DE, H69K, A71I, L89T, I93LC
 RenG10585RenG10585KT741613PINAI50L W6S, Q7D, R8G, K14R, I15V, G16E, K20R, E34R, E35D, M36I, R41N, K45R, R57RK, H69KQ, A71IV, V77I, V82VI, L89T, I93LC
 RenG10735RenG10735KT741763PINA  I15V, E35G, M36I, N37Q, R41N, D60E, L63P, H69K, L89T, I93LC