<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation N88S
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 24
Isolates 24
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M58M58AY010420NFV M46MI, N88SL10LFT12S, I15V, L19IV, K20T, E35ED, M36I, R41K, L63V, H69K, T74S, L89M, I93LC
Gibb (2002)DMG104104_w66 NFV66N88SQ58QET12S, I15V, L19I, K20T, E35D, M36I, R41K, K45R, D60E, Q61E, L63P, H69K, L89M, I93LC
Grossman (2004)IL178IL178AY529547NFV65N88S L19KT, K20T, T31TK, E35D, M36I, R41K, K45KR, L63P, H69K, L89M, I93LC
Weber (2005)M66914M66914AY677473NFV192M46MI, N88S I15V, K20IM, E35ED, M36I, R41RK, L63LP, I64IV, H69K, L89M, I93LC
Doualla-Bell (2006)Pt12FDB_Pt12 NFV N88S T12S, I15V, L19I, M36I, R41K, L63P, I64L, H69K, I93LC
 Pt5FDB_Pt5 NFV N88SL10FI15V, L19I, K20T, E35D, M36I, R41K, Q61H, L63T, H69K, T74S, L89M, I93LC
 Pt6FDB_Pt6 NFV M46I, N88SL10FT12S, I15V, L19V, K20I, M36I, R41K, L63V, I64V, H69K, T74V, L89M, I93LC
Pillay (2008)DR37DR37AY589894NFV M46I, N88S, L90ML10FT12S, I13V, I15V, L19I, K20T, M36I, R41K, L63P, H69K, L89I, I93LC
 DR60DR60AY589912RTV M46I, N88S T12S, I15V, L19I, K20I, E35D, M36I, N37D, R41RK, D60E, L63P, H69K, A71AT, I72L, I93LC
Waleria-Aleixo (2008)RES277RES277FJ591976PINAN88SQ58EI15V, K20T, E35D, M36I, N37T, R41K, K45R, R57K, D60E, L63PT, H69K, L89M, I93LC
Saravanan (2013)YRG61YRG61KC016256PINAM46I, I54V, N88S T12S, I15V, L19I, K20I, E35G, M36I, R41K, I62V, L63P, H69K, T74A, L89M, I93LC
Diaz (2015)RenG16711RenG16711KT747739PINAI54IV, N88S L10V, I15V, G16E, K20R, E35D, M36IV, N37K, P39S, R41N, K45KR, I62V, H69K, A71AV, T74S, L89M, I93LC
 RenG17106RenG17106KT748134PINAI50L, V82VA, N88SL33FI13V, K14R, I15V, K20KR, E35D, M36I, N37K, R41N, K45KR, Q61N, I64IV, H69K, A71IV, T74S, L89M, I93LC
 RenG14874RenG14874KT745902PINAM46I, N88S I15V, K20T, E35D, M36I, N37K, R41N, L63T, I64IV, H69K, T74S, L89M, I93LC
 RenG13551RenG13551KT744579PINAM46MI, I50V, I54V, V82M, N88SL33F, Q58E, T74PL10V, G16E, K20R, E35D, M36I, N37K, R41N, R57RK, L63T, H69K, L89F, I93LC
 RenG14844RenG14844KT745872PINAM46I, I54V, V82A, N88SL10F, L33F, L89VI13V, I15V, K20T, E21EK, E35D, M36IL, N37K, R41N, I62V, L63P, H69K, G73D, T74S, I93ILC
 RenG13278RenG13278KT744306PINAI54IL, I84V, N88SL33F, Q58EL10Y, I13V, I15V, K20R, E35D, M36I, N37K, R41N, K45R, R57K, D60E, Q61E, I62V, L63P, H69K, A71T, L89M, I93LC
 RenG13275RenG13275KT744303PINAN88SL10F, Q58EI13V, I15V, E35D, M36I, N37K, R41N, I62V, L63P, H69K, L89I, I93LC
 RenG12637RenG12637KT743665PINAM46I, N88SF53LL10Y, I15V, K20T, E35G, M36I, N37D, R41K, L63V, I64V, H69K, T74A, L89M, I93LC
 RenG12578RenG12578KT743606PINAN88SL89IMVL10V, I13V, I15V, K20R, A22ACGS, E35D, M36I, N37K, R41N, K45R, I62IV, L63P, H69K, I93LC
 RenG10615RenG10615KT741643PINAI50L, N88SL33F, T74PI13IV, I15V, K20R, E35D, M36I, N37K, R41N, L63LP, H69K, A71V, L89M, I93LC
 RenG10491RenG10491KT741519PINAI50L, V82VA, N88S, L90LML33FL10M, I13V, I15IV, K20R, E35D, M36I, N37K, R41N, K45R, H69K, A71V, L89I, I93LC
Novitsky (2015)bcpp_395bcpp_395KR860753PINAM46I, N88S T12P, I15V, L19I, K20I, E35G, M36I, R41K, Q61E, L63P, H69K, T74A, L89M, I93LC
Posada Cespedes (2017)249209.ZA.GT933KX540398ATV I50L, N88SL33F, G73ST12S, I13V, I15V, L19I, K20R, E35D, M36I, R41K, K45R, L63P, H69K, A71VC