<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation N88D
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 37
Isolates 39
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG8686_w82 NFV65D30NL10F, N88D, L89VT12S, I13V, I15V, L19I, E35D, M36L, N37E, K45R, D60E, L63P, H69K, I93LC
 DMG9191_w22 NFV22D30NL10F, N88D, L89VT12S, I13V, I15V, L19I, E35D, M36L, N37E, K45R, D60E, L63P, H69K, I93LC
Grossman (2004)IL160IL160AY529612SQV, NFV128D30NN88DT12S, I15V, L19I, K20I, M36I, P39PS, R41K, K45R, L63T, H69K, A71IV, I93LC
 IL217IL217AY529576NFV104D30NN88DL10I, I13V, K14R, I15V, K20R, E35D, M36I, R41K, L63Q, I64IV, H69Q, L89IM, I93LC
 IL477IL477AY529602NFV208D30NL10F, N88DT12S, I15V, L19V, K20T, E35D, M36I, N37D, R41K, L63V, I64M, H69K, L89M, I93LC
Non-B Workgroup (2005)UK1518UK1518AY900807NFV68D30NN88DT12S, I15V, L19V, K20T, E35D, M36I, N37NS, R41K, H69K, T74S, L89M, I93LC
 UK2069UK2069AY900845NFV D30NN88DT12S, I13V, I15V, Q18H, L19I, K20R, E35D, M36I, R41K, L63V, H69K, T74S, L89I, I93LC
 SA75_DR16SA75_DR16AY901099NFV D30NL10F, V32VA, N88DI15IL, G16E, L19I, E35D, M36IV, R41K, Y59YF, Q61E, I62IV, H69K, T74S, L89M, I93L, N98KC
 TK3027TK3027 RTV, SQV, NFV190D30N, L90MN88DT12S, I13V, I15V, L19I, K20R, E35D, M36I, N37D, I62IV, L63P, H69K, T74S, L89I, I93LC
  TK3027b RTV, SQV, NFV, LPV276D30DN, L90LMN88DT12S, I13IV, I15V, L19I, K20R, E35D, M36I, N37ND, R41RK, L63P, H69K, T74S, L89IM, I93LC
 TK3031TK3031 SQV, NFV203D30NN88DI15V, L19I, K20T, E35G, M36I, R41K, G51GR, L63S, H69K, T74A, L89M, I93LC
 PL4706685002 IDV, NFV104D30NN88DT12S, I13V, I15V, L19I, E35ED, M36I, R41K, L63P, H69K, T74A, L89M, I93LC
Rhee (2005)CA7907CA24813AY797580IDV, NFV260D30NL10F, N88DT12P, K14R, I15V, G16E, K20IT, E35G, M36V, R41K, L63T, H69Q, T74S, V77VI, I85IV, L89M, I93LC
Doualla-Bell (2006)Pt13FDB_Pt13 NFV D30N, M46IL10F, N88DI15V, M36I, R41K, L63P, H69K, I93LC
 Pt8FDB_Pt8 NFV D30NL33F, N88DT12S, I15V, G16E, L19I, M36L, R41K, L63Q, H69K, L89IC
 Pt9FDB_Pt9 NFV D30NL33F, N88DT12S, I15V, L19I, M36I, R41K, I62V, L63P, H69K, T74A, L89IM, I93LC
von Wyl (2007)41662849EF449918PINAD30NN88DI15V, E35D, M36I, N37K, R41HN, L63P, H69K, A71AV, I85IV, I93LC
Pillay (2008)DR1602ZA.DR16AY589877NFV D30NL10F, V32VA, N88DI15IL, G16E, L19I, E35D, M36IV, R41K, Y59YF, Q61E, I62IV, H69K, T74S, L89M, I93L, N98KC
Kandathil (2009)VL06_253VL06_253EU030406PINAD30NN88D, L89VL10M, T12S, I13V, I15V, L19T, K20T, E21D, E35K, M36I, P39A, R41K, K45R, Q61D, L63P, H69K, T74S, V82I, I93LC
Kouri (2012)CU1452-09CU1452-09JQ585296PINAD30N, I54M, L90ML33F, N88DT12S, I13V, K14R, I15V, E35D, M36I, N37S, R41K, L63P, H69K, T74S, L89I, I93LC
Grossman (2014)255255KF135031SQV, LPV52I54V, V82AL10F, N88D, L89VT12S, I13V, I15V, L19I, K20R, E35D, M36I, R57K, L63P, H69K, A71V, T74S, I93LC
  255KF135032SQV, LPV90M46I, I54V, V82AL10F, L33F, N88D, L89VT12S, I13V, I15V, L19I, E35D, M36I, N37D, R57K, L63P, H69K, T74S, I93LC
 217217KF135024NFV, LPV52D30N, I54V, V82AL33F, N88DL10I, I13V, K14R, I15V, K20R, E35D, M36I, R41K, L63Q, H69Q, V75I, L89I, I93LC
 943943 LPV379M46I, L90ML10F, N88DT12S, I15V, L19I, K20R, E35D, M36I, R41K, K55R, L63P, H69K, L89M, I93LC
 160160KF134989SQV, LPV52D30NN88DT12V, L19I, K20I, M36I, R41K, K45R, L63T, H69K, A71V, I93LC
Diaz (2015)RenG16894RenG16894KT747922PINAD30N, M46I, I54V, V82AL10F, L24I, L33F, N88DT12P, I13IV, K14KR, I15V, L19LP, K20KM, E35D, M36L, N37K, R41N, K55KR, R57RK, L63P, H69K, Q92QKC
 RenG16300RenG16300KT747328PINAD30N, L90LML10LF, N88DI13V, I15V, E35D, M36I, N37K, R41N, K45R, L63AP, I64IV, H69K, L89I, I93LC
 RenG16715RenG16715KT747743PINAD30N, I54LN88DL10Y, I15V, L19Q, K20T, E35D, M36I, N37K, R41N, L63V, H69K, A71T, L89T, I93LC
 RenG16280RenG16280KT747308PINAD30N, I50ILN88D, L89AITVK14KR, I15V, L19I, K20T, M36IV, N37KR, R41NY, Q61H, H69K, A71IV, T74S, I85V, I93LC
 RenG14709RenG14709KT745737PINAD30N, M46MI, V82AL10F, L24I, L33F, N88DT12P, I15V, K20T, E35N, M36I, N37K, R41N, K45R, L63P, H69K, V75I, I93LC
 RenG14050RenG14050KT745078PINAD30NL10F, N88DK14KR, I15V, K20T, E35D, M36I, N37K, R41N, L63P, H69Q, I72IV, V75I, L89M, I93LC
 RenG14536RenG14536KT745564PINAD30N, I54ILM, I84IVL10F, L33F, N88DI15V, G16E, K20T, E35D, M36I, N37EK, P39S, R41N, K45I, L63T, H69K, T74AS, I85V, L89M, I93ILC
 RenG14186RenG14186KT745214PINAD30N, M46L, I54V, V82AQ58QE, N88DL10R, I15V, K20T, E35D, M36I, N37K, R41N, D60DE, Q61QH, L63P, I64IL, H69K, A71V, L89I, I93LC
 RenG14024RenG14024KT745052PINAD30N, I50L, V82AL33F, N88DL10LR, I13V, I15IV, K20KRT, E35D, M36I, N37E, P39PS, R41N, K45KR, L63P, H69K, A71AV, T74S, V77VI, L89IM, I93LC
 RenG11098RenG11098KT742126PINAD30NN88DI13V, K14KR, I15V, K20T, E35D, M36I, N37Q, R41NS, D60E, Q61N, L63Q, H69K, T74A, V77VI, L89M, I93LC
 RenG11593RenG11593KT742621PINAD30NN88DI13V, I15V, K20R, E35D, M36I, N37K, R41N, L63P, H69K, T74S, L89M, I93LC
 RenG10573RenG10573KT741601PINAD30NN88DI13V, I15V, K20Q, E35G, M36I, N37K, R41N, K45R, L63P, H69K, T74S, L89I, I93LC
 RenG11741RenG11741KT742769PINAM46MI, I54V, V82A, L90ML33F, K43T, N88DL10V, I13V, K20R, E35D, M36I, N37K, R41N, I62V, L63P, H69K, A71V, T74KR, L89M, I93LC
 RenG10498RenG10498KT741526PINAD30N, I50L, V82VAL33F, N88DI13V, I15V, K20R, E35D, M36I, N37E, P39PS, R41N, K45KR, L63P, G68GE, H69K, A71AITV, T74S, L89M, I93LC

Database

Resources

Team