<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation V82I
Rx >= 1 PI
IncludeMixtures No
References 20
Patients 85
Isolates 94
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M6M6AY010422SQV   T12S, I15V, G16E, L19Q, M36I, N37R, R41N, Q61N, L63A, H69K, V82I, L89M, I93LC
 NY_M62M62AY010425SQV   T12S, I15V, G16E, L19Q, M36I, N37R, R41N, Q61N, L63A, H69K, V82I, L89M, I93LC
Gibb (2002)DMG8585_w19 NFV17  T12S, I15V, L19I, E35D, M36I, R41K, D60DE, L63LAPV, H69K, V82I, L89M, I93LC
  85_w50 NFV36  T12S, I15V, L19I, K20KT, E35D, M36I, R41K, L63LV, H69K, V82I, L89M, I93LC
Kantor (2002)TCDD-01TCDD-01AY090840NFV22  T12S, I15V, L19I, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63I, E65D, H69K, V82I, L89M, I93LC
 TCDD-13TCDD-13_1AY090847SQV69  T12TS, I15V, L19LI, L24L*, M36I, R41K, L63LAPV, H69K, V82I, L89LM, I93LC
 TCDD-26TCDD-26AY090852SQV38  I15V, L19X, M36I, R41K, L63V, H69K, V82I, L89M, I93LC
 TCDD-23TCDD-23_1AY090850SQV205L90M I15V, L19I, M36I, R41K, D60E, L63P, H69K, V82I, L89M, I93LC
Shafer (2003)A384_09730973bEF548178Unknown, RTV, IDV>5  I15V, L19IMT, M36I, R41K, H69K, K70KR, V82I, L89M, I93LC
Montes (2004)MB_patNIB01_NIB719AJ577965NFV94L90ML23IT12S, I13V, I15V, L19I, K20T, E35D, M36I, N37R, R41N, Q61E, L63A, I64M, H69K, V82I, L89M, I93LC
Non-B Workgroup (2005)UK243UK243AY900766IDV, NFV L90ML23IT12S, I15V, L19I, E35G, M36I, R41K, L63P, H69K, K70R, V82I, I93LC
 UK449UK449 SQV, NFV, RTV L90ML23IT12S, L19I, E35D, M36I, R41K, D60E, L63S, H69K, V82I, L89M, I93L, L97XC
 UK1154UK1154AY900795NFV L90M T12S, I13V, I15V, L19I, K20T, E35D, M36I, R41K, D60E, L63P, I64V, H69K, V82I, L89M, I93LC
 UK1461UK1461AY900805NFV35 L23IT12S, I15V, L19I, K20T, E35D, M36I, R41K, D60E, H69K, V82I, L89M, I93LC
 IL273IL273 NFV, IDV, RTV137  I15V, M36I, R41K, L63T, H69K, V82I, L89M, I93LC
 UK1461bUK1461b NFV35L90LML23IT12S, I15V, L19I, K20T, E35D, M36I, R41K, D60E, H69K, V82I, L89M, I93LC
 TK4001TK4001 NFV2  T12S, I15V, L19T, M36I, R41K, Q61E, L63P, H69K, V82I, L89M, I93LC
Weber (2005)M83284M83284AY677471SQV82  T12S, I15V, L19I, M36L, L63V, H69K, T74S, V82I, L89M, I93LC
Baxter (2006)12-31023102-30610DQ877250PINAL90ML23I, L33F, F53L, Q58EL10I, T12P, I15V, G16E, L19V, K20R, E35D, M36I, N37T, I62V, L63T, H69K, T74A, V82I, I85V, L89M, I93LC
 48-80328032-30707DQ879070PINAL90LM T12S, I15V, L19I, M36I, R41K, L63P, H69K, K70KR, V82I, I93LC
 48-80568056-30930DQ879080PINAV32I, I47AL33F, Q58EL10I, T12S, I15V, L19I, K20T, M36I, D60E, L63P, H69K, T74A, V82I, I85V, L89M, I93LC
Doualla-Bell (2006)Pt2FDB_Pt2 NFV L90M T12S, I13V, I15V, L19V, K20T, E35G, M36I, R41K, H69K, K70R, A71V, T74S, V82I, L89I, I93LC
von Wyl (2007)735326978EF449871PINA  T12S, I15V, G16E, L19Q, M36I, R41K, L63P, H69K, V82I, I93LC
Marconi (2008)SW090SW090EU308099LPV   T12S, I15V, L19T, E35D, M36I, R41K, K45R, D60E, I62V, L63P, H69K, V82I, L89M, I93LC
Kandathil (2009)VL06_253VL06_253EU030406PINAD30NN88D, L89VL10M, T12S, I13V, I15V, L19T, K20T, E21D, E35K, M36I, P39A, R41K, K45R, Q61D, L63P, H69K, T74S, V82I, I93LC
Kassaye (2009)TCDD-13TC13_2003FJ445709SQV, NFV178  I15V, L19LI, M36I, R41K, L63V, H69K, V82I, I93LC
 TCDD-23TC23_2003FJ445712SQV304L90M I15V, L19I, K20M, M36I, R41K, D60E, L63P, H69Q, V82I, L89M, I93LC
 TC-68TC68_2004FJ445724NFV, LPV17I54L, L90LML10LFI15V, L19I, K20T, E35DG, M36I, N37S, R41K, I64L, H69K, V82I, I85V, L89M, I93LC
Dau (2010)07344A07344AGU581841PINAL90M T12S, I13V, I15V, L19I, K20T, M36I, N37ND, R41K, L63P, H69K, V82I, L89M, I93LC
El-Khatib (2010)Pat11511ZA_SAVE2347JF960565LPV   T12S, I15V, L19I, N37S, R41K, L63P, H69K, V77I, V82I, I93LC
 Pat12211ZA_SAVE2434JF960572LPV   T12S, I15V, L19T, M36I, R41K, H69K, V82I, L89M, I93LC
Rodrigues (2010)305_07BR07SC305GQ401315NFV L90ML89VI13V, I15V, K20T, E35G, M36I, N37K, R41N, I62V, H69K, I72IV, T74S, V82I, I93LC
Barber (2012)5103051030JQ361665LPV I54V T12S, I15V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89M, I93LC
Van Zyl (2013)89684KC424309LPV26  F53FS, L63S, H69K, V82I, L89M, I93LC
 12931097KC422875LPV26  T12S, I15V, L19I, E35D, R41K, L63P, H69K, V82I, L89M, I93LC
 907525KC424117LPV26  T12S, I15V, L19I, N37S, R41K, L63P, H69K, V77I, V82I, I93LC
 11691618KC423273LPV26  T12S, K14R, I15V, G16E, L19V, M36I, N37K, R41K, K43R, R57K, L63T, H69K, V82I, L89M, I93LC
 16371520KC423201LPV26  T12S, L19T, K20R, M36I, R41K, L63T, H69K, V82I, L89M, I93LC
 12371075KC422861LPV26  I15V, L19T, E35ED, M36I, L63S, H69K, V82I, L89M, I93LC
  1535KC423210LPV78  I15V, L19T, E35D, M36I, L63S, H69K, V82I, L89M, I93LC
 712200KC423553LPV26  T12TS, I15V, L19I, M36I, R41K, H69K, K70R, V82I, L89M, I93LC
  919KC424362LPV78  I15V, L19IV, M36I, R41K, H69K, K70R, V82I, L89M, I93LC
 13852410KC423695LPV26  T12S, K14R, I15V, L19I, M36I, R41K, L63T, H69K, V82I, L89M, I93LC
 3101069KC422855LPV26  T12S, L19T, K20R, M36I, R41K, L63AP, H69K, V82I, L89M, I93LC
 14071550KC423222LPV26I54V, I84V T12S, I13V, I15V, G16E, L19I, K20T, M36I, R41K, K45V, D60E, Q61E, I66V, H69K, K70R, I72V, V82I, L89M, I93LC
 6321066KC422852LPV26I54IV T12S, I15V, L19I, E35D, M36I, R41K, H69K, V82I, L89I, I93LC
 1542970KC424405LPV26  T12S, I15V, L19I, L63P, H69K, V77I, V82I, L89M, I93LC
 1182872KC424328LPV26  T12S, I15V, G17GD, L19I, E35D, M36I, R41K, L63P, H69K, V82I, L89M, I93LC
 1144265KC423761LPV26  K14N, I15V, L19I, M36I, L63V, H69K, V82I, L89M, I93LC
  767KC424273LPV78  K14N, I15V, L19I, M36I, L63V, H69K, V82I, L89M, I93LC
 15022120KC423633LPV26  T12S, I15V, L19I, K20KR, M36I, R41K, L63V, H69K, V82I, L89M, I93LC
 18072458KC423722LPV26  T12S, I15V, L19T, K20KR, E35D, Q61E, L63P, H69K, V77I, V82I, L89M, I93LC
 14742008KC423558LPV26  T12S, L19I, N37S, P39S, R41K, L63P, H69K, V77I, V82I, L89M, I93LC
 16631227KC422977LPV26  I15V, L19I, E35D, M36I, R57RK, H69K, V82I, L89M, I93LC
 16252876KC423870LPV26  T12S, L19I, M36I, R41K, L63P, H69K, V82I, L89M, I93LC
 4242011KC423562LPV26  T12S, I15V, L19I, M36I, R41K, D60E, H69K, V82I, L89M, I93LC
 9872786KC423828LPV26  T12S, I15V, L19I, M36I, R41K, D60E, H69K, V82I, L89M, I93LC
 5091492KC423182LPV26  T12S, I15V, L19T, E35D, M36I, R41K, L63P, H69K, V77I, V82I, L89M, I93LC
 15612198KC423677LPV26  I15V, L19T, M36I, R41K, Q61E, L63P, H69K, V82I, I93LC
 7051933KC423519LPV104  K14R, L19I, M36I, N37S, R41K, L63A, H69K, V82I, L89M, I93LC
 6471624KC423279LPV209  T12S, I15V, G16E, L19T, N37S, R57K, L63V, H69K, V77I, V82I, L89M, I93LC
 4171502KC423191LPV26  I15V, L19T, K20R, E35D, M36I, R41K, H69K, V82I, L89M, I93LC
 17252001KC423554LPV26  T12S, I15IV, G16E, L19I, M36MI, R41K, K43R, L63Q, H69K, V77I, V82I, L89I, I93LC
 808993KC424422LPV1  T12S, K14R, I15V, L19I, M36I, R41K, L63V, H69K, V82I, L89M, I93LC
 3662886KC423875LPV104  T12S, L19I, M36V, D60E, I62V, L63P, H69K, V82I, L89M, I93LC
 803209KC423610LPV26  T12S, I15V, L19I, M36I, R41K, D60E, H69K, V82I, L89M, I93LC
  1241KC422992LPV130  T12S, I15V, L19I, M36I, R41K, D60E, H69K, V82I, L89M, I93LC
 675575KC424149LPV26  T12S, L19I, M36I, N37S, R41K, L63S, H69K, V82I, L89M, I93LC
 6192891KC423878LPV26  T12S, I15V, L19I, K20R, M36I, R41K, H69K, V77I, V82I, L89M, I93LC
 9582147KC423651LPV26  I15V, L19T, K20R, M36I, R41K, H69K, V77I, V82I, L89M, I93LC
 3011085KC422869LPV26  T12S, I15V, L19I, M36I, H69K, V82I, L89M, I93LC
Grossman (2014)882882KF135160NFV, LPV52M46I, I50V, I54V, L90ML23II13V, K20T, L33V, E35D, M36I, R41RK, K55KNRS, I62IV, H69K, T74S, V82I, L89I, I93LC
 250250KF135030SQV, LPV52L90M K14R, I15V, M36I, N37D, R41K, I62V, H69K, T74S, V82I, I85V, L89I, I93LC
 512512KF135092LPV52  I13V, K14R, I15V, K20T, M36I, R41K, H69K, V82I, L89M, I93LC
 166166KF134995LPV52  T12S, I15V, G16E, L19I, M36I, R41K, Q61N, L63C, H69K, V82I, I93LC
 860860KF135156LPV52  T12TS, I15V, L19I, M36IL, N37NS, L63HPQ, H69K, V82I, L89M, I93LC
  860KF135157LPV203  I15V, L19IV, M36IL, N37NS, L63HP, H69K, V82I, L89M, I93LC
 18871887KF135009LPV52  K14R, I15V, L19Q, M36I, R41K, L63V, H69K, V82I, L89M, I93LC
 11041104KF134945LPV52  Q7K, T12S, I15V, L19I, M36I, R41K, H69K, V82I, L89M, I93LC
  1104KF134947LPV116  T12TS, I15V, L19I, M36I, R41K, H69K, V82I, L89M, I93LC
 18331833 LPV52  I15V, M36I, R41K, H69K, V82I, L89M, I93LC
 464464 NFV, IDV, LPV52V32I, I47V, I54MN83DL10I, M36I, R41K, I62V, L63V, T74S, V82I, I85V, L89I, I93LC
 744744 LPV52  T12A, I15V, M36I, L63P, H69E, P79A, V82I, L89M, I93LC
Steegen (2014)12ZAKS28712ZAKS287KJ176566LPV   R41K, Q61E, H69K, V82I, L89M, I93LC
 11ZAKS11111ZAKS111KJ176393LPV   R41K, L63T, I64IL, H69K, V82I, L89M, I93LC
 11ZAKS10311ZAKS103KJ176385LPV   R41K, L63V, E65D, H69K, K70R, V77I, V82I, L89M, I93LC
 12ZAKS20812ZAKS208KJ176488LPV   R41K, R57K, D60E, H69K, V82I, L89M, I93LC
 11ZAKS11311ZAKS113KJ176395LPV  Q58ER41K, Q61E, L63P, H69K, V82I, L89M, I93LC
 11ZAKS10511ZAKS105KJ176387LPV   R41K, H69K, V82I, L89M, I93LC
 11ZAKS14411ZAKS144KJ176426LPV   R41K, D60E, Q61E, H69K, V82I, L89M, I93LC
 11ZAKS11711ZAKS117KJ176399LPV M46L, I47A, I84V R41K, K45R, L63P, H69Q, I72V, V82I, I93LC
 12ZAKS24712ZAKS247KJ176526LPV   R41K, D60E, Q61E, L63P, H69K, K70Q, V82I, L89M, I93LC
 12ZAKS29112ZAKS291KJ176570LPV M46I, I47A, I54VK43TR41K, R57K, D60E, L63P, H69K, A71V, V82I, L89M, I93LC
 12ZAKS26712ZAKS267KJ176546LPV   R41N, I62V, L63H, H69K, I72IV, V82I, L89I, I93LC